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    • 1. 发明申请
    • METHOD FOR REGULATING THE GROWTH OF PREADIPOCYTES USING SONIC VIBRATION
    • 使用声波振幅调节预处理器生长的方法
    • WO2009142454A3
    • 2010-03-04
    • PCT/KR2009002712
    • 2009-05-22
    • UNIV DONGGUK IND ACAD COOPPARK JUNG KENGYOON MOON YOUNGHAN MI JUNG
    • PARK JUNG KENGYOON MOON YOUNGHAN MI JUNG
    • C12N5/0775
    • C12N5/0667C12N2521/10
    • The present invention relates to a method of regulating the growth of preadipocytes by using sonic vibration, involving: treating preadipocytes with sonic vibration having a frequency range of 1 to 10 Hz so as to stimulate the growth of preadipocytes; or alternatively, treating preadipocytes with sonic vibration having a frequency range of 11 to 50 Hz so as to suppress the growth of preadipocytes. The method of the present invention can prevent or treat obesity in a safe and effective manner by suppressing the growth of preadipocytes using sonic vibration with a specific frequency range. Further, when an implantable biomaterial is prepared by using preadipocytes and transplanted into the body, the method of the present invention can stimulate the growth of preadipocytes, and thereby, promote the engraftment of the implantable biomaterial.
    • 本发明涉及通过使用声音振动来调节前脂肪细胞生长的方法,涉及:用频率范围为1〜10Hz的声音振动处理前脂肪细胞,以刺激前脂肪细胞的生长; 或者以具有11〜50Hz的频率范围的声音振动处理前脂肪细胞,以抑制前脂肪细胞的生长。 本发明的方法可以通过使用具有特定频率范围的声音振动来抑制前脂肪细胞的生长而以安全有效的方式预防或治疗肥胖。 此外,当通过使用前脂肪细胞并移植到体内制备可植入生物材料时,本发明的方法可以刺激前脂肪细胞的生长,从而促进可植入生物材料的移植。