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1. 发明申请

WO2007054373A1 COMPOSITION AND ITS USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING, PROPHYLACTICALLY TREATING, PREVENTING CANCER AND/OR INFECTIONS IN THE URINARY TRACT 审中-公开
标题翻译：组合物及其制造用于治疗，预防性治疗，预防癌症和/或感染的药物在URNARY TRACT中的用途
公开(公告)号：WO2007054373A1
公开(公告)日：2007-05-18
申请号：PCT/EP2006/010924
申请日：2006-11-14
申请人： NOLABS AB , PETERS, Tor , WIKLUND, Peter
发明人： PETERS, Tor , WIKLUND, Peter
IPC分类号： A61K9/51 , A61K9/16 , A61K47/16 , A61K47/34 , A61K33/00 , A61P35/00
CPC分类号： A61K31/785 , A61K9/0034 , A61K33/00
摘要： A composition is provided that allows for treatment of cancer, prophylactic treatment, and treatment of infection in the urinary tract. The composition comprises a nitric oxide (NO) eluting polymer that elutes nitric oxide (NO) in a therapeutic dose. The nitric oxide (NO) eluting polymer may be integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO). The nitric oxide (NO) eluting polymer may be provided as a Solution or Suspension. Furthermore, a manufacturing method for said composition is disclosed, as well as uses of said composition in the urinary tract.
摘要翻译：提供了能够治疗癌症，预防性治疗和尿道感染治疗的组合物。该组合物包含以治疗剂量洗脱一氧化氮（NO）的一氧化氮（NO）洗脱聚合物。一氧化氮（NO）洗脱聚合物可以与载体材料整合，使得所述载体材料在使用中调节并控制所述治疗剂量的一氧化氮（NO）的洗脱。可以提供一氧化氮（NO）洗脱的聚合物作为溶液或悬浮液。此外，公开了所述组合物的制造方法，以及所述组合物在尿道中的用途。

2. 发明申请

WO2006100154A1 COSMETIC TREATMENT WITH NITRIC OXIDE, DEVICE FOR PERFORMING SAID TREATMENT AND MANUFACTURING METHOD THEREFOR 审中-公开
标题翻译：具有氧化氮的化妆品处理，用于实现其处理的设备及其制造方法
公开(公告)号：WO2006100154A1
公开(公告)日：2006-09-28
申请号：PCT/EP2006/050884
申请日：2006-02-13
申请人： NOLABS AB , PETERS, Tor
发明人： PETERS, Tor
IPC分类号： A61L15/44 , A61L27/34 , A61L27/54
CPC分类号： A61K8/19 , A61K8/0208 , A61K8/84 , A61K2800/54 , A61L15/44 , A61L2300/114 , A61L2300/602 , A61Q19/00 , A61Q19/06 , A61Q19/08
摘要： A cosmetic treatment method, and a device therefor, are provided that allow for cosmetic treatment of cosmetic disorders, caused by chronological age, environmental factors, changes in physiological functions of skin, such as psoriasis, dermatitis, acne, cellulites, and viral and/or bacteriological attacks. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the area to be cosmetically treated, such that a cosmetic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said cosmetic dosage of nitric oxide (NO). Furthermore, a manufacturing method for said device is provided.
摘要翻译：提供了一种美容治疗方法及其装置，其允许美容治疗由时间年龄，环境因素，皮肤的生理功能的变化引起的美容障碍，例如牛皮癣，皮炎，痤疮，脂肪团，以及病毒和/ 或细菌攻击。该装置包括一个一氧化氮（NO）洗脱聚合物，该聚合物被布置成接触待化妆处理的区域，使得化妆品剂量的一氧化氮从所述一氧化氮洗脱聚合物洗脱到所述区域。一氧化氮（NO）洗脱聚合物与载体材料整合，使得所述载体材料在使用中调节并控制所述化妆品剂量的一氧化氮（NO）的洗脱。此外，提供了用于所述装置的制造方法。

3. 发明申请

WO2006084911A2 IMPROVED DEVICE FOR APPLICATION OF MEDICAMENTS, MANUFACTURING METHOD THEREFOR, AND METHOD OF TREATMENT 审中-公开
标题翻译：用于应用药物的改进的装置，其制造方法和治疗方法
公开(公告)号：WO2006084911A2
公开(公告)日：2006-08-17
申请号：PCT/EP2006050890
申请日：2006-02-13
申请人： NOLABS AB , PETERS TOR
发明人： PETERS TOR
CPC分类号： A61K9/7023 , A61K31/04 , A61K31/155 , A61K31/16 , A61K31/785 , A61K33/00 , A61L15/44 , A61L26/0066 , A61L2300/104 , A61L2300/114 , A61L2300/402 , A61L2300/41 , A61L2300/45 , A61L2300/622 , A61K2300/00
摘要： A therapeutic treatment device is provided, which comprises a compound comprising a drug and a nitric oxide (NO) eluting polymer arranged to contact a treatment site in or on a body. The device is acting as a booster for drug eluting patches, e.g. pharmaceuticals, vitamins, nicotin, nitroglycerin, whereby with advantage two therapeutic treatments, of significant value, are combined in one treatment. A synergetic effect is achieved by such devices because NO that is eluted from the device boosts the effect of the drug, as the treatment site is more susceptible to said drug by the effect of the eluted NO.
摘要翻译：提供了一种治疗治疗装置，其包括包含药物和布置成接触体内或身体上的治疗部位的一氧化氮（NO）洗脱聚合物的化合物。该装置用作药物洗脱斑块的增强剂，例如药物，维生素，烟碱，硝酸甘油，其中两种具有重要价值的治疗方法在一种治疗中相结合。通过这种装置实现协同效应，因为从装置洗脱的NO增强了药物的作用，因为处理部位通过洗脱的NO的作用对所述药物更敏感。

4. 发明申请

WO2007023005A1 DEVICE, SYSTEM, AND METHOD COMPRISING MICROENCAPSULATED PROTON DONOR FOR RELEASE OF NITRIC OXIDE FROM A POLYMER 审中-公开
标题翻译：包含用于从聚合物中释放出氧化氮的微型放电原子发射器的装置，系统和方法
公开(公告)号：WO2007023005A1
公开(公告)日：2007-03-01
申请号：PCT/EP2006/050902
申请日：2006-02-13
申请人： NOLABS AB , PETERS, Tor
发明人： PETERS, Tor
IPC分类号： A61K9/70 , A61K9/50 , A61K33/00
CPC分类号： A61K9/7007 , A61K9/5057 , A61K9/5078 , A61K9/5084 , A61K9/70 , A61K9/7023 , A61K33/00
摘要： A device, comprising an NO eluting polymer is provided. Said device is furthermore provided with microencapsulated proton donor (102), such as water, body fluids, alcohols in micro-capsules (101), which water, body fluids, alcohols after breakage of said micro capsules, initiate elution of NO from said device. Furthermore, a manufacturing method for said device is disclosed.
摘要翻译：提供了包含NO洗脱聚合物的装置。所述装置还具有微胶囊化的质子供体（102），例如微胶囊（101）中的水，体液，醇，所述微胶囊破裂后的水，体液，醇开始从所述装置中溶出NO 。此外，公开了一种用于所述装置的制造方法。

5. 发明申请

WO2006100156A3 INTRAVASCULAR, INTERSTITIAL OR INTRAORGAN MEDICAL ACCESS DEVICE, AND MANUFACTURING METHOD THEREOF, INVOLVING NITRIC OXIDE 审中-公开
公开(公告)号：WO2006100156A3
公开(公告)日：2006-09-28
申请号：PCT/EP2006/050896
申请日：2006-02-13
申请人： NOLabs AB , PETERS, Tor
发明人： PETERS, Tor
IPC分类号： A61L27/54 , A61L29/16 , A61L31/16 , A61K31/785 , A61L29/08
摘要： A intravascular, interstitial or intraorgan medical device, and a manufacturing process of said medical device, is provided that allows for prevention of infection and obtainment of anti-thrombotic effect. The medical device comprises a nitric oxide (NO) eluting polymer arranged adjacent mammal tissue, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said mammal tissue. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO) . Furthermore, a manufacturing method for said device is disclosed.

6. 发明申请

WO2006100156A2 INTRAVASCULAR, INTERSTITIAL OR INTRAORGAN MEDICAL ACCESS DEVICE, AND MANUFACTURING METHOD THEREOF, INVOLVING NITRIC OXIDE 审中-公开
标题翻译：内镜，内窥镜或内窥镜医疗访问装置及其制造方法，涉及氧化氮
公开(公告)号：WO2006100156A2
公开(公告)日：2006-09-28
申请号：PCT/EP2006050896
申请日：2006-02-13
申请人： NOLABS AB , PETERS TOR
发明人： PETERS TOR
IPC分类号： A61L27/54 , A61K31/785 , A61L29/08 , A61L29/16 , A61L31/16
CPC分类号： A61L29/16 , A61K31/785 , A61L29/085 , A61L2300/114 , C08L79/08
摘要： A intravascular, interstitial or intraorgan medical device, and a manufacturing process of said medical device, is provided that allows for prevention of infection and obtainment of anti-thrombotic effect. The medical device comprises a nitric oxide (NO) eluting polymer arranged adjacent mammal tissue, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said mammal tissue. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO) . Furthermore, a manufacturing method for said device is disclosed.
摘要翻译：提供血管内，间质或者内部的医疗装置以及所述医疗装置的制造方法，其允许预防感染和获得抗血栓形成作用。医疗装置包括邻近哺乳动物组织布置的一氧化氮（NO）洗脱聚合物，使得治疗剂量的一氧化氮从所述一氧化氮洗脱聚合物洗脱到所述哺乳动物组织。一氧化氮（NO）洗脱聚合物与载体材料整合，使得所述载体材料在使用中调节并控制所述治疗剂量的一氧化氮（NO）的洗脱。此外，公开了一种用于所述装置的制造方法。

7. 发明申请

WO2006084910A2 DEVICE AND METHOD FOR TREATMENT OF DERMATOMYCOSIS, AND IN PARTICULAR ONYCHOMYCOSIS 审中-公开
标题翻译：用于治疗皮肤病和特别的自身免疫性疾病的装置和方法
公开(公告)号：WO2006084910A2
公开(公告)日：2006-08-17
申请号：PCT/EP2006/050889
申请日：2006-02-13
申请人： NOLABS AB , PETERS, Tor
发明人： PETERS, Tor
CPC分类号： A61K9/7023 , A61F13/064 , A61F13/068 , A61F13/10 , A61F13/105 , A61L15/26 , A61L15/44 , A61L2300/114 , A61L2300/404 , A61L2300/602 , C01B21/24 , C08L79/02
摘要： A device is provided that allows for target treatment of infections, caused by dermatophytes, yeast fungus, and 5 mould fungus, such as onychomycosis and dermatophytosis. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the infected area, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) 10 eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO). Furthermore, a corresponding manufacturing method is provided.
摘要翻译：提供了一种装置，其允许目标治疗由皮肤癣菌，酵母真菌和霉菌真菌引起的感染，例如甲真菌病和皮肤癣菌病。所述装置包括与所述感染区域接触的一氧化氮（NO）洗脱聚合物，使得治疗剂量的一氧化氮从所述一氧化氮洗脱聚合物洗脱到所述区域。一氧化氮（NO）10洗脱聚合物与载体材料整合，使得所述载体材料在使用中调节并控制所述治疗剂量的一氧化氮（NO）的洗脱。此外，提供了相应的制造方法。

8. 发明申请

WO2008116497A1 TOPICAL TERMAL DELIVERY DEVICE FOR NITRIC OXIDE DELIVERY 审中-公开
标题翻译：用于氮氧化物输送的局部输送装置
公开(公告)号：WO2008116497A1
公开(公告)日：2008-10-02
申请号：PCT/EP2007/052923
申请日：2007-03-27
申请人： NOLabs AB , LINDGREN, Lars , MÅRLIND, Linda , THORSEN, Rikard
发明人： LINDGREN, Lars , MÅRLIND, Linda , THORSEN, Rikard
IPC分类号： A61K9/70 , A61L15/44 , A61K33/00
CPC分类号： A61K9/703 , A61F2013/00646 , A61K9/7084 , A61K33/00 , A61L15/44 , A61L2300/114 , A61L2300/602 , A61M35/00
摘要： A topical dermal delivery device, such as a patch, for topical delivery of nitric oxide (NO) to treatment sites of mammals is disclosed. In an embodiment the patch has three layers; a backing with an activation window, a absorbent core as a reservoir and an NO permeable membrane with an adhesive layer towards the skin. The NO donor is applied into the device as a solution prior to application through the activation window. The window is closed after activation and the lid and backing is non-permeable for NO in order to increase the partial pressure of NO and thus the concentration of dissolved NO. The patch is fixated on the area to be treated with an adhesive layer that also assures sufficient contact throughout the treatment. The generated NO moves within the patch and can escape through the NO permeable membrane towards the area to be treated. Depending on therapy needed, the patch release curve differs and is chosen accordingly.
摘要翻译：公开了用于将一氧化氮（NO）局部递送到哺乳动物的处理部位的局部皮肤递送装置，例如贴片。在一个实施例中，贴片具有三层; 具有活化窗的背衬，作为储存器的吸收芯和具有朝向皮肤的粘合剂层的NO可渗透膜。 NO供体在通过激活窗口施加之前作为解决方案施加到设备中。活化后窗口关闭，盖子和背衬对于NO是不可渗透的，以增加NO的分压，从而增加溶解NO的浓度。该贴片固定在待处理的区域上，该粘合剂层在整个治疗过程中也保证足够的接触。所产生的NO在贴片内移动，并且可以通过NO渗透膜向待处理的区域逸出。根据需要的治疗，补片释放曲线不同，并相应地选择。

9. 发明申请

WO2006084910A3 DEVICE AND METHOD FOR TREATMENT OF DERMATOMYCOSIS, AND IN PARTICULAR ONYCHOMYCOSIS 审中-公开
标题翻译：用于治疗皮肤病和特别的自身免疫性疾病的装置和方法
公开(公告)号：WO2006084910A3
公开(公告)日：2007-03-08
申请号：PCT/EP2006050889
申请日：2006-02-13
申请人： NOLABS AB , PETERS TOR
发明人： PETERS TOR
IPC分类号： A61L15/44 , A61K47/30 , A61L27/34 , A61L27/54 , A61L31/12 , A61L31/16 , A61P31/10 , C01B21/24
CPC分类号： A61K9/7023 , A61F13/064 , A61F13/068 , A61F13/10 , A61F13/105 , A61L15/26 , A61L15/44 , A61L2300/114 , A61L2300/404 , A61L2300/602 , C01B21/24 , C08L79/02
摘要： A device is provided that allows for target treatment of infections, caused by dermatophytes, yeast fungus, and 5 mould fungus, such as onychomycosis and dermatophytosis. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the infected area, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) 10 eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO). Furthermore, a corresponding manufacturing method is provided.
摘要翻译：提供了一种装置，其允许目标治疗由皮肤癣菌，酵母真菌和霉菌真菌引起的感染，例如甲真菌病和皮肤癣菌病。所述装置包括与所述感染区域接触的一氧化氮（NO）洗脱聚合物，使得治疗剂量的一氧化氮从所述一氧化氮洗脱聚合物洗脱到所述区域。一氧化氮（NO）10洗脱聚合物与载体材料整合，使得所述载体材料在使用中调节并控制所述治疗剂量的一氧化氮（NO）的洗脱。此外，提供了相应的制造方法。

10. 发明申请

WO2006084913A3 DEVICE FOR TREATMENT OF RECTAL DISORDERS, AND MANUFACTURING PROCESS FOR THE SAME, INVOLVING NITRIC OXIDE 审中-公开
公开(公告)号：WO2006084913A3
公开(公告)日：2006-08-17
申请号：PCT/EP2006/050892
申请日：2006-02-13
申请人： NOLABS AB , PETERS, Tor
发明人： PETERS, Tor
IPC分类号： A61L27/54 , A61L29/16 , A61L31/16 , A61L27/34 , A61L29/08 , A61L31/10 , A61K31/74 , A61K31/785
摘要： A device for therapeutic treatment of rectal disorders, including fissures, ulcers, haemorrhoids, and levator spasm, is disclosed. The device comprises a nitric oxide (NO) eluting polymer configured for eluting a therapeutic dosage of nitrogen oxide (NO) when used for the treatment. Furthermore, the device is configured for exposing a rectal treatment site of said rectal disorder in or on a rectal region of a body to said nitric oxide when said polymer elutes nitrogen oxide (NO). The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO). Moreover a method of manufacturing such a rectal treatment device is disclosed.

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