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1. 发明申请

US20220354906A1 Probiotic Immunomodulatory Compositions 有权
公开(公告)号：US20220354906A1
公开(公告)日：2022-11-10
申请号：US17714205
申请日：2022-04-06
申请人： Uute Scientific Oy
发明人： Aki Sinkkonen , Mira Grõnroos , Heikki Hyöty , Olli-Heikki Laitinen , Noora Nurminen , Sami Oikarinen
IPC分类号： A61K35/742 , A61K8/96 , A61K8/99 , A61K9/00 , A61K35/10 , A61K35/747
摘要： The invention discloses an immunomodulatory composition comprising non-culturable bacteria, a method of production and an article and an apparatus for its use and administration.

2. 发明授权

US11376231B2 Compositions of bioactive fulvate fractions and uses thereof 有权
$Compositions of bioactive fulvate fractions and uses thereof$
公开(公告)号：US11376231B2
公开(公告)日：2022-07-05
申请号：US16805606
申请日：2020-02-28
申请人： OMNI BIOCEUTICAL INNOVATIONS, INC.
发明人： Gary W. Black , Jane Christensen , Farhan Taghizadeh
IPC分类号： A61K31/194 , A61K8/96 , A61Q19/00 , A61K31/352 , A61Q19/08 , A61K35/10 , A61K8/36 , A61K8/64 , A61K9/00 , A61K45/06
摘要： Compositions with fulvate fractions alone or in combination with growth factors, bioactive fragmented peptides, or combinations thereof are disclosed herein. Also disclosed are methods of using said compositions for the catalyzing cellular regeneration, including the healing, treatment, or prevention of skin disorders. Also disclosed are methods for extracting, isolating, and purifying fulvate fractions for use in the manufacture of said compositions.

3. 发明申请

US20200368189A1 COMPOSITIONS OF BIOACTIVE FULVATE FRACTIONS AND USES THEREOF 审中-公开
公开(公告)号：US20200368189A1
公开(公告)日：2020-11-26
申请号：US16805606
申请日：2020-02-28
申请人： OMNI BIOCEUTICAL INNOVATIONS, INC.
发明人： Gary W. Black , Jane Christensen , Farhan Taghizadeh
IPC分类号： A61K31/194 , A61K8/96 , A61Q19/00 , A61K31/352 , A61Q19/08 , A61K35/10 , A61K8/36 , A61K8/64 , A61K9/00 , A61K45/06
摘要： Compositions with fulvate fractions alone or in combination with growth factors, bioactive fragmented peptides, or combinations thereof are disclosed herein. Also disclosed are methods of using said compositions for the catalyzing cellular regeneration, including the healing, treatment, or prevention of skin disorders. Also disclosed are methods for extracting, isolating, and purifying fulvate fractions for use in the manufacture of said compositions.

4. 发明申请

US20190274972A1 CBD Alkaline Water With Fulvic Acid 审中-公开
公开(公告)号：US20190274972A1
公开(公告)日：2019-09-12
申请号：US15919156
申请日：2018-03-12
申请人： Michael Ochoa
发明人： Michael Ochoa
IPC分类号： A61K31/05 , A61K35/10
摘要： Disclosed herein is an alkaline water solution including CBD oil mixed homogeneously with the alkaline water. In a second exemplary embodiment, Fulvic Acid is added to the solution of CBD oil and alkaline water. In general, the CBD oil makes up no more than 3% of the alkaline water solution and no more than 2000 mg in a 15 ounce container. In the solution including Fulvic Acid, a 15 ounce solution contains between 5 mg and 15 mg.

5. 发明授权

US08894993B2 Mitochondria-targeted antioxidants 有权
标题翻译：线粒体靶向的抗氧化剂
公开(公告)号：US08894993B2
公开(公告)日：2014-11-25
申请号：US11881630
申请日：2007-07-27
申请人： Shibnath Ghosal
发明人： Shibnath Ghosal
IPC分类号： A61K38/43 , A61K38/54 , A61K31/122 , A23L1/30 , A23L2/52 , A61K8/34 , A61K8/44 , A61K31/37 , A61K35/10 , A61Q19/08 , A61Q17/04
CPC分类号： A61K31/122 , A23L2/52 , A23L33/10 , A61K8/347 , A61K8/442 , A61K31/37 , A61K35/10 , A61Q17/04 , A61Q19/08 , A61K2300/00
摘要： The present invention relates to a pharmaceutical or veterinary or nutritional or personal care composition comprising coenzyme Q10 (CoQ10), reduced CoQ10, or mixtures thereof and oxygenated dibenzo-α-pyrone or an amino acyl ester thereof. The composition of the present invention is able to support and/or provide therapy to individuals at risk and/or under treatment for dysfunctions of energy metabolism, and specifically, for mitochondrial diseases.
摘要翻译：本发明涉及包含辅酶Q10（CoQ10），还原的CoQ10或其混合物和含氧二苯并-α-吡喃酮或其氨基酰基酯的药物或兽医或营养或个人护理组合物。本发明的组合物能够支持和/或提供治疗患有风险和/或治疗能力代谢功能障碍，特别是针对线粒体疾病的个体。

6. 发明授权

US5486538A Precious metal humates and their preparations 失效
标题翻译：贵金属腐殖酸及其制备方法
公开(公告)号：US5486538A
公开(公告)日：1996-01-23
申请号：US298419
申请日：1994-08-29
申请人： Bernhard Seubert , Anton F. Haase
发明人： Bernhard Seubert , Anton F. Haase
IPC分类号： A61K35/10 , C08H99/00 , A61K31/28 , C07F1/12 , C07F15/00
CPC分类号： C08H99/00 , A61K35/10
摘要： A precious metal salt of a low molecular humic acid containing 1 to 5% by weight of the precious metal processes for their preparation and a method of stabilizing alkali metal humate and their medical uses.
摘要翻译：含有1至5重量％贵金属制备方法的低分子腐殖酸的贵金属盐以及稳定碱金属腐殖酸盐及其医疗用途的方法。

7. 发明授权

US4487766A Growth stimulants and compositions containing same 失效
标题翻译：生长兴奋剂和含有它的组合物
公开(公告)号：US4487766A
公开(公告)日：1984-12-11
申请号：US469129
申请日：1983-02-23
申请人： Walter J. Mach
发明人： Walter J. Mach
IPC分类号： A23K20/10 , A23K20/111 , A23K20/20 , A23K50/30 , A61K35/10 , C07H1/00 , A61K31/715
CPC分类号： A23K50/30 , A23K20/10 , A23K20/111 , A23K20/30
摘要： Biochemically active materials having anabolic bioactivity for favorably influencing the intracellular and systemic metabolism of higher organisms are disclosed. The materials consist of water-soluble acid carbonization products of lignoid natural materials in the form of decationized alkali salts and have their catabolic activity at least in part inhibited by reaction with trace metal ions. The active material carbonization products are produced by treating lignoid natural material with an aqueous alkali hydroxide solution. The resulting solution is adjusted to a weakly acid pH and treated with a trace metal salt solution. The reaction mixture thus obtained was dried, optionally after addition of a suitable carrier product. Also described are growth-promoting agents, particularly suited for animal feed supplements, as well as therapeutic agents which contain this active material useful in treating metabolism disturbances of higher organisms or for use with disturbances of the metabolism.
摘要翻译：公开了具有合成代谢生物活性以有利地影响高等生物体的细胞内和全身代谢的生物活性物质。该材料由木质素天然材料的水溶性酸性碳酸化产物组成，其形式为脱碱化的碱式盐，并且其分解代谢活性至少部分地被微量金属离子反应抑制。通过用碱金属氢氧化物水溶液处理木质素天然材料来生产活性物质碳化产物。将所得溶液调节至弱酸性pH并用痕量金属盐溶液处理。将如此获得的反应混合物干燥，任选地在加入合适的载体产物之后。还描述了特别适用于动物饲料补充剂的生长促进剂，以及含有用于治疗高等生物体的代谢紊乱或用于代谢紊乱的活性物质的治疗剂。

8. 发明授权

US11065298B1 Compositions and methods for treating or preventing viral infections 有权
公开(公告)号：US11065298B1
公开(公告)日：2021-07-20
申请号：US16896092
申请日：2020-06-08
申请人： Chanda Zaveri , Meng Teng Lim
发明人： Chanda Zaveri , Meng Teng Lim
IPC分类号： A61K38/10 , A61K9/00 , A61P31/14 , A61K35/10 , A61P31/22 , A61P31/16
摘要： Compositions and methods disclosed herein may be used for treating or preventing viral infections. The compositions may be administered orally to subjects in need of preventative or therapeutic treatment and/or the compositions may be used to disinfect surfaces in order to prevent or limit the spread of disease through surface contact.

9. 发明申请

US20170327790A1 METHOD OF PREPARING AUTOLOGOUS CELLS AND METHODS OF USE FOR THERAPY 审中-公开
公开(公告)号：US20170327790A1
公开(公告)日：2017-11-16
申请号：US15664988
申请日：2017-07-31
申请人： BioCardia, Inc.
发明人： Didier Rouy , Peter A. Atlman , Benjamin Koziner
IPC分类号： C12N5/0775 , A61K35/10 , A61K9/00 , A61K35/00 , A61K35/28 , C12Q1/68 , A61K35/12
CPC分类号： C12N5/0663 , A61K9/0019 , A61K35/00 , A61K35/10 , A61K35/28 , A61K2035/124 , C12N2500/84 , C12N2502/11 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158
摘要： A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium which can be used in a clinical setting, and a business method for performing such expansions in the future as a service for patients. A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium including a diagnostic kit for the autologous cell therapy to determine whether a patient will respond to the autologous cell therapy for treatment of a disease, in which said kit comprising a system for detecting gene and protein expression comprising at least two isolated DNA molecules wherein each isolated DNA molecule detects expression of a gene that is differentially expressed in the tissue of the patient that is intended to be the source of the autologous cell therapy.

10. 发明授权

US09752123B2 Method of preparing autologous cells and methods of use for therapy 有权
公开(公告)号：US09752123B2
公开(公告)日：2017-09-05
申请号：US15055418
申请日：2016-02-26
申请人： BioCardia, Inc.
发明人： Didier Rouy , Peter A. Atlman , Benjamin Koziner
IPC分类号： C12N5/00 , C12N5/0775 , A61K35/00 , A61K35/10 , A61K9/00 , A61K35/28 , A61K35/12 , C12Q1/68
CPC分类号： C12N5/0663 , A61K9/0019 , A61K35/00 , A61K35/10 , A61K35/28 , A61K2035/124 , C12N2500/84 , C12N2502/11 , C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158
摘要： A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium which can be used in a clinical setting, and a business method for performing such expansions in the future as a service for patients. A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium including a diagnostic kit for the autologous cell therapy to determine whether a patient will respond to the autologous cell therapy for treatment of a disease, in which said kit comprising a system for detecting gene and protein expression comprising at least two isolated DNA molecules wherein each isolated DNA molecule detects expression of a gene that is differentially expressed in the tissue of the patient that is intended to be the source of the autologous cell therapy.

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