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1. 发明授权

US07273759B2 Plate alignment and sample transfer indicia for a multiwell multiplate stack and method for processing biological/chemical samples using the same 失效
标题翻译：多孔堆叠的板对准和样品转移标记以及使用其进行生物/化学样品处理的方法
公开(公告)号：US07273759B2
公开(公告)日：2007-09-25
申请号：US10236953
申请日：2002-09-09
申请人： Jonathan L. Coffman , Hong Lu , Ernest J. Wodds, III
发明人： Jonathan L. Coffman , Hong Lu , Ernest J. Wodds, III
IPC分类号： G01N1/10
CPC分类号： B01L3/50255 , B01L3/5025 , G01N1/405 , G01N35/1095 , G01N2001/388 , G01N2035/00237 , G01N2035/00277 , G01N2035/00485 , Y10T436/2575
摘要： Device and method for processing samples are provided. A first multiwell plate is stacked atop a second multiwell plate. The first multiwell plate has x wells arranged in an array, each well is capable of receiving a sample and has an outlet. The second multiwell plate has y wells arranged in an array, each well being capable of receiving a separate sample. y>x. The outlets of the first multiwell plate register with inlets of a subset of wells of the second multiwell plate when the first plate is stacked atop the second plate. Also provided are a mechanism for aligning the plates and transfer indicia for tracking transfer of sample from the first to the second plate. A mechanism for sealing the first plate to the second plate is provided so that samples can be directly transferred between the plates without cross-contamination occurring in open wells of the second plate.
摘要翻译：提供了处理样品的装置和方法。第一多孔板堆叠在第二多孔板上。第一个多孔板具有排列成阵列的x个孔，每个孔能够接收样品并具有出口。第二个多孔板具有以阵列排列的y个孔，每个孔能够接收单独的样品。 y> x。当第一板堆叠在第二板顶上时，第一多孔板的出口对准第二多孔板的孔子集的入口。还提供了用于对准板和传送标记以跟踪样品从第一板到第二板的转移的机构。提供了将第一板密封到第二板的机构，使得样品可以在板之间直接传递，而不会在第二板的开放井中发生交叉污染。

2. 发明申请

US20010003915A1 Exhaust gas analyzing system 有权
标题翻译：废气分析系统
公开(公告)号：US20010003915A1
公开(公告)日：2001-06-21
申请号：US09729474
申请日：2000-12-04
发明人： Kaori Inoue , Masayuki Adachi
IPC分类号： G01N027/00
CPC分类号： G01N33/0018 , G01N1/2252 , G01N1/38 , G01N2001/2264 , G01N2001/388
摘要： The present invention provides an exhaust gas analyzing system utilizing a mini-diluter method in which measurement accuracy of the exhaust gas analyzing system can be evaluated by the system itself. In the exhaust gas analyzing system, a sampling flow path is connected to an exhaust gas flow path through which gas exhausted from an engine flows to sample a portion of the exhaust gas. The sampled exhaust gas is diluted with dilution gas introduced through a dilution gas flow path which is connected in parallel to the sampling flow path. A portion of the diluted exhaust gas is stored in a sample bag. The diluted exhaust gas in the sample bag is analyzed in a gas analyzing portion, wherein flow rate of the exhaust gas is measured, trace gas with a known concentration is introduced into the exhaust gas flow path upstream from a connecting point located between the exhaust gas flow path and the sampling flow path while monitoring flow rate of the trace gas, diluted trace gas is analyzed in the gas analyzing portion, and total mass of the trace gas calculated from a result of the analysis is compared with total mass of the introduced trace gas to evaluate measurement itself.
摘要翻译：本发明提供一种利用微型稀释法的废气分析系统，其中废气分析系统的测量精度可以通过系统本身进行评估。在废气分析系统中，采样流路连接到排气流路，废气从发动机排出的气体通过该排气流路对废气的一部分进行取样。将采样废气用通过与采样流路平行连接的稀释气体流路引入的稀释气体稀释。一部分稀释废气储存在样品袋中。在气体分析部分中分析样品袋中的稀释废气，其中测量排气的流量，将已知浓度的痕量气体引入排气流动路径中，位于排气之间的连接点流量路径和采样流程，同时监测痕量气体的流量，在气体分析部分分析稀释的痕量气体，并将从分析结果计算的痕量气体的总质量与引入痕量的总质量进行比较气体来评估测量本身。

3. 发明授权

US4801805A Method of measuring multicomponent constituency of gas emission flow 失效
标题翻译：测量气体排放流量多组分选区的方法
公开(公告)号：US4801805A
公开(公告)日：1989-01-31
申请号：US87171
申请日：1987-08-19
申请人： James W. Butler , Paul D. Maker , Thomas J. Korniski , Alex D. Colvin
发明人： James W. Butler , Paul D. Maker , Thomas J. Korniski , Alex D. Colvin
IPC分类号： G01J3/45 , G01J3/28 , G01J3/453 , G01N1/28 , G01N1/38 , G01N21/35 , G01N33/00 , G01N21/37
CPC分类号： G01N33/0016 , G01J3/453 , G01N21/3504 , G01J2003/2866 , G01N1/38 , G01N2001/383 , G01N2001/388 , G01N2021/3595 , G01N2201/1215
摘要： A method is disclosed of making an on-line gas analysis of a multicomponent gas emission flow by (a) continuously sequestering a sample flow from the gas emission flow, which sample flow has been filtered to substantially eliminate solid or liquid particles, diluted to lower its dew point to below room temperature, and changed in either temperature and/or pressure to be substantially the same in temperature and pressure as that of gases used to create reference transmission frequency spectral data deployed in step (d); (b) continuously irradiating the sample flow with an electromagnetic radiation beam while modulating the amplitude of infrared frequencies in the audio frequency range of the beam, either prior to or immediately subsequent to irradiation of the sample flow, to produce electromagnetic signals having discernible amplitude variations resulting from spectral interference patterns; (c) detecting and collecting the signals at a sufficiently high rate to substantially completely distinguish between adjacent spectral pattern amplitude peaks without mutual spectral interference and to permit analysis of the signals in real time; and (d) analyzing the signals in real time by (i) mathematically manipulating the signals in accordance with Beer's Law to create reformed background-corrected data, and (ii) applying reference transmission frequency spectral data to the reformed data for each suspected gaseous component to give a linear quantitative measure of the presence of each and every suspected gas component in the gas emission flow.

4. 发明申请

US20100170683A1 GAS ACTIVITY ANALYSIS IN THE GROUND 审中-公开
标题翻译：地下气体活动分析
公开(公告)号：US20100170683A1
公开(公告)日：2010-07-08
申请号：US12641579
申请日：2009-12-18
申请人： Michael HEISEL
发明人： Michael HEISEL
IPC分类号： E21B43/22
CPC分类号： E21B43/166 , E21B47/1015 , G01N2001/388
摘要： A method of introducing a propellant gas into the ground is described, wherein a trace gas that can be analysed above the ground or the earth's surface is added to said propellant gas. According to the invention hydrogen is used as the trace gas, whereby the proportion of the trace gas hydrogen in the propellant gas/trace gas mixture is a maximum of 10% by vol., preferably a maximum of 5% by vol.
摘要翻译：描述了将推进剂气体引入地面的方法，其中可以将分析在地面或地球表面上的痕量气体加入到所述推进剂气体中。根据本发明，使用氢作为痕量气体，由此推进剂气体/微量气体混合物中痕量气体氢的比例最大为10体积％，最好为5体积％。

5. 发明授权

US06464942B2 Plate alignment and sample transfer indicia for a multiwell multiplate stack and method for processing biological/chemical samples using the same 失效
标题翻译：多孔堆叠的板对准和样品转移标记以及使用其进行生物/化学样品处理的方法
公开(公告)号：US06464942B2
公开(公告)日：2002-10-15
申请号：US09316850
申请日：1999-05-21
申请人： Jonathan L. Coffman , Hong Lu , Ernest J. Woods, III
发明人： Jonathan L. Coffman , Hong Lu , Ernest J. Woods, III
IPC分类号： B01L300
CPC分类号： B01L3/50255 , B01L3/5025 , G01N1/405 , G01N35/1095 , G01N2001/388 , G01N2035/00237 , G01N2035/00277 , G01N2035/00485 , Y10T436/2575
摘要： Device and method for processing biological, biochemical or chemical samples are provided wherein a first multiwell plate is stacked atop a second multiwell plate. The first multiwell plate has x wells arranged in a regular array, each capable of receiving a separate sample. Each well of the x wells has an outlet at a lower surface of the first plate. The second multiwell plate has y wells arranged in a regular array, each well of the y wells being capable of receiving a separate sample, and wherein y>x. The outlets at the lower surface of the first multiwell plate are arrayed to register with corresponding inlets of a subset of the y wells of the second multiwell plate when the first plate is stacked atop the second plate. A mechanism for aligning the first plate to the second plate is provided, as well as transfer indicia for tracking transfer of sample from the first plate to the second plate. Also, a mechanism for sealing,the first plate to the second plate is provided so that samples can be directly transferred between the first plate and the second plate without cross-contamination occurring in open wells of the second plate.
摘要翻译：提供了用于处理生物，生化或化学样品的装置和方法，其中第一多孔板堆叠在第二多孔板上。第一个多孔板具有排列成规则阵列的x个孔，每个能够接收单独的样品。 x孔的每个孔在第一板的下表面具有出口。第二多孔板具有以规则阵列排列的y孔，y孔的每个孔能够接收单独的样品，并且其中y> x。第一多孔板的下表面处的出口排列成与第二多孔板的y阱的子集的相应入口对准，当第一板堆叠在第二板的顶部时。提供了用于将第一板与第二板对准的机构，以及用于跟踪将样品从第一板传递到第二板的标记。此外，设置用于密封第一板到第二板的机构，使得样品可以在第一板和第二板之间直接传递，而不会在第二板的开放井中发生交叉污染。

6. 发明授权

US06412333B2 Exhaust gas analyzing system 有权
标题翻译：废气分析系统
公开(公告)号：US06412333B2
公开(公告)日：2002-07-02
申请号：US09729474
申请日：2000-12-04
申请人： Kaori Inoue , Masayuki Adachi
发明人： Kaori Inoue , Masayuki Adachi
IPC分类号： G01N1910
CPC分类号： G01N33/0018 , G01N1/2252 , G01N1/38 , G01N2001/2264 , G01N2001/388
摘要： The present invention provides an exhaust gas analyzing system utilizing a mini-diluter method in which measurement accuracy of the exhaust gas analyzing system can be evaluated by the system itself. In the exhaust gas analyzing system, a sampling flow path is connected to an exhaust gas flow path through which gas exhausted from an engine flows to sample a portion of the exhaust gas. The sampled exhaust gas is diluted with dilution gas introduced through a dilution gas flow path which is connected in parallel to the sampling flow path. A portion of the diluted exhaust gas is stored in a sample bag. The diluted exhaust gas in the sample bag is analyzed in a gas analyzing portion, wherein flow rate of the exhaust gas is measured, trace gas with a known concentration is introduced into the exhaust gas flow path upstream from a connecting point located between the exhaust gas flow path and the sampling flow path while monitoring flow rate of the trace gas, diluted trace gas is analyzed in the gas analyzing portion, and total mass of the trace gas calculated from a result of the analysis is compared with total mass of the introduced trace gas to evaluate measurement itself.
摘要翻译：本发明提供一种利用微型稀释法的废气分析系统，其中废气分析系统的测量精度可以通过系统本身进行评估。在废气分析系统中，采样流路连接到排气流路，废气从发动机排出的气体通过该排气流路对废气的一部分进行取样。将采样废气用通过与采样流路平行连接的稀释气体流路引入的稀释气体稀释。一部分稀释废气储存在样品袋中。在气体分析部分中分析样品袋中的稀释废气，其中测量排气的流量，将已知浓度的痕量气体引入排气流动路径中，位于排气之间的连接点流量路径和采样流程，同时监测痕量气体的流量，在气体分析部分分析稀释的痕量气体，并将从分析结果计算的痕量气体的总质量与引入痕量的总质量进行比较气体来评估测量本身。

7. 发明申请

US20160071713A1 ION IMPLANTATION SYSTEM AND PROCESS FOR ULTRASENSITIVE DETERMINATION OF TARGET ISOTOPES 有权
标题翻译：离子植入系统和目标同位素超敏检测方法
公开(公告)号：US20160071713A1
公开(公告)日：2016-03-10
申请号：US14482332
申请日：2014-09-10
申请人： Orville T. Farmer, III , Martin Liezers
发明人： Orville T. Farmer, III , Martin Liezers
IPC分类号： H01J49/04 , H01J49/00 , H01J37/317
CPC分类号： H01J49/0459 , G01N1/405 , G01N1/44 , G01N2001/388 , H01J37/05 , H01J37/3171 , H01J49/04
摘要： A system and process are disclosed for ultrasensitive determination of target isotopes of analytical interest in a sample. Target isotopes may be implanted in an implant area on a high-purity substrate to pre-concentrate the target isotopes free of contaminants. A known quantity of a tracer isotope may also be implanted. Target isotopes and tracer isotopes may be determined in a mass spectrometer. The present invention provides ultrasensitive determination of target isotopes in the sample.
摘要翻译：公开了用于对样品中分析感兴趣的目标同位素进行超灵敏测定的系统和方法。目标同位素可以植入高纯度底物的植入区域，以预先浓缩没有污染物的目标同位素。也可以植入已知量的示踪剂同位素。目标同位素和示踪剂同位素可以在质谱仪中测定。本发明提供样品中目标同位素的超敏感测定。

8. 发明申请

US20030008412A1 Plate alignment and sample transfer indicia for a multiwell multiplate stack and method for processing biological/chemical samples using the same 失效
标题翻译：多孔堆叠的板对准和样品转移标记以及使用其进行生物/化学样品处理的方法
公开(公告)号：US20030008412A1
公开(公告)日：2003-01-09
申请号：US10236953
申请日：2002-09-09
申请人： CIPHERGEN BIOSYSTEMS, INC.
发明人： Jonathan L. Coffman , Hong Lu , Ernest J. Woods III
IPC分类号： B01L003/00 , G01N001/10
CPC分类号： B01L3/50255 , B01L3/5025 , G01N1/405 , G01N35/1095 , G01N2001/388 , G01N2035/00237 , G01N2035/00277 , G01N2035/00485 , Y10T436/2575
摘要： Device and method for processing samples are provided. A first multiwell plate is stacked atop a second multiwell plate. The first multiwell plate has x wells arranged in an array, each well is capable of receiving a sample and has an outlet. The second multiwell plate has y wells arranged in an array, each well being capable of receiving a separate sample. y>x. The outlets of the first multiwell plate register with inlets of a subset of wells of the second multiwell plate when the first plate is stacked atop the second plate. Also provided are a mechanism for aligning the plates and transfer indicia for tracking transfer of sample from the first to the second plate. A mechanism for sealing the first plate to the second plate is provided so that samples can be directly transferred between the plates without cross-contamination occurring in open wells of the second plate.
摘要翻译：提供了处理样品的装置和方法。第一多孔板堆叠在第二多孔板上。第一个多孔板具有排列成阵列的x个孔，每个孔能够接收样品并具有出口。第二个多孔板具有以阵列排列的y个孔，每个孔能够接收单独的样品。 y> x。当第一板堆叠在第二板顶上时，第一多孔板的出口对准第二多孔板的孔子集的入口。还提供了用于对准板和传送标记以跟踪样品从第一板到第二板的转移的机构。提供了将第一板密封到第二板的机构，使得样品可以在板之间直接转移，而不会在第二板的开放井中发生交叉污染。

9. 发明申请

US20020182746A1 Method and device for sample introduction of volatile analytes 审中-公开
标题翻译：用于样品引入挥发性分析物的方法和装置
公开(公告)号：US20020182746A1
公开(公告)日：2002-12-05
申请号：US09867663
申请日：2001-05-31
发明人： Zoltan Mester , Ralph Sturgeon
IPC分类号： G01N001/38
CPC分类号： G01N1/40 , G01N2001/388 , Y10T436/24 , Y10T436/255 , Y10T436/2575 , Y10T436/25875
摘要： The present invention relates to a simple thermal desorption gas introduction interface for sample introduction of volatile analytes into an atomic spectroscopic detector. An injector is connected to the atomic spectroscopic detector via a first port. The injector further comprises a sealed second port for inserting the volatile analyte bound to an extraction phase. A heating block surrounding the injector heats the injector to a predetermined temperature and keeps it substantially at the predetermined temperature. A carrier gas flow of inert gas is provided into the injector through a third port of the injector located in proximity to the second port. An auxiliary gas flow of inert gas is provided via forth port located between the third port and the atomic spectroscopic detector. The volatile analyte bound to an extraction phase is inserted into the injector, wherein the extraction phase is inserted through the seal of the second port for sealed exposure within the injector. The volatile analyte is then rapidly thermally desorbed from the extraction phase through application of the heat and provision of the carrier gas flow and transported to the atomic spectroscopic detector in a gas flow comprising the carrier gas flow and the auxiliary gas flow.
摘要翻译：本发明涉及用于将挥发性分析物引入原子光谱检测器的简单热解吸气体引入界面。注射器通过第一端口连接到原子光谱检测器。注射器还包括用于插入与提取相结合的挥发性分析物的密封的第二端口。围绕喷射器的加热块将喷射器加热至预定温度并将其保持在预定温度。通过位于第二端口附近的喷射器的第三端口将惰性气体的载气流提供到喷射器中。通过位于第三端口和原子光谱检测器之间的第四端口提供惰性气体的辅助气流。与萃取相结合的挥发性分析物被插入到喷射器中，其中提取阶段通过第二端口的密封件插入，用于在喷射器内密封曝光。挥发性分析物然后通过施加热和提供载气流从萃取相快速解吸，并以包含载气流和辅助气流的气流输送到原子光谱检测器。

10. 发明授权

US5145750A Rubber product identification by tagging 失效
标题翻译：橡胶产品通过标签识别
公开(公告)号：US5145750A
公开(公告)日：1992-09-08
申请号：US602543
申请日：1990-10-24
申请人： James A. Davis , Kenneth R. Lucas
发明人： James A. Davis , Kenneth R. Lucas
IPC分类号： C08J5/18 , C08K3/00 , C08K3/22 , C08K3/30 , C08L21/00 , E04D5/06 , G01N1/38 , G01N33/44 , G06K19/06
CPC分类号： G06K19/06009 , C08K3/22 , C08K3/30 , G01N33/445 , C08K2003/2262 , C08K2003/3045 , G01N2001/388 , Y10S428/917 , Y10T428/256 , Y10T428/31826
摘要： The present invention provides for a method for positive product identification using tagging materials such as barium sulfate, manganese dioxide or mixtures thereof. Such materials may be employed, for example, in the dusting agent used in roofing materials, and applied to one or both sides of rubber roofing sheeting or admixed with the compounding ingredients during the preparation of the sheeting composition. The tagging materials can be detected and identified in the finished product by X-ray fluorescence spectroscopy.

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