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1. 发明申请

US20150045515A1 NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT-FROM COMPOSITIONS 审中-公开
标题翻译：非反应性，抗微生物，抗组氨酸衍生物
公开(公告)号：US20150045515A1
公开(公告)日：2015-02-12
申请号：US14531383
申请日：2014-11-03
申请人： Jun LI , Zheng ZHANG , Chad C. HUVAL , Michael A. BOUCHARD , Christopher R. LOOSE , Arthur J. COURY
发明人： Jun LI , Zheng ZHANG , Chad C. HUVAL , Michael A. BOUCHARD , Christopher R. LOOSE , Arthur J. COURY
IPC分类号： C08F255/02 , C08G77/38 , C08G18/83 , C08G64/42
CPC分类号： C08F255/02 , A61L29/06 , A61L29/085 , A61L33/0088 , C08F291/00 , C08G18/836 , C08G64/42 , C08G77/38 , C08J7/16 , C08J7/18 , C08J2323/12 , C08J2369/00 , C08J2383/04 , C08J2433/14 , Y10T428/24355 , Y10T428/265 , Y10T442/30 , Y10T442/60 , C08F220/00
摘要： A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 μg/mL fibrinogen derived from human plasma containing 1.4 μg/mL I-125 radiolabeled fibrinogen.
摘要翻译：一种用于制备和产生的制品的方法，包括具有表面，表面下面的体积的基材和在基材表面上的接枝聚合物层，基底表面和接枝聚合物层的组合，构成具有在纤维蛋白原结合测定中纤维蛋白原吸附量小于约125ng / cm 2，其中将修饰的表面在37℃下在70μg/ mL来自含有1.4μg/ mL I-125放射性标记的纤维蛋白原的人血浆的纤维蛋白原中温育60分钟。

2. 发明申请

US20140194537A1 METHOD FOR PRODUCING DISPERSANT ADDITIVES 有权
标题翻译：生产分散添加剂的方法
公开(公告)号：US20140194537A1
公开(公告)日：2014-07-10
申请号：US14127861
申请日：2012-05-05
申请人： Bernd Göbelt , René Nagelsdiek , Jürgen Omeis , Frederik Piestert , Wolfgang Pritschins , Natasa Meznaric , Daniela Schröder , Werner Tiegs
发明人： Bernd Göbelt , René Nagelsdiek , Jürgen Omeis , Frederik Piestert , Wolfgang Pritschins , Natasa Meznaric , Daniela Schröder , Werner Tiegs
IPC分类号： B01F17/00
CPC分类号： B01F17/0092 , B01F17/0042 , B01F17/005 , B01F17/0064 , C08G18/0814 , C08G18/0819 , C08G18/0823 , C08G18/10 , C08G18/282 , C08G18/2825 , C08G18/283 , C08G18/284 , C08G18/2865 , C08G18/2875 , C08G18/3275 , C08G18/3281 , C08G18/61 , C08G18/615 , C08G18/7621 , C08G18/8064 , C08G18/836 , C08K5/5455 , C09D7/45
摘要： The present invention relates to a method for producing an additive composition which in particular contains specific urea urethanes. The additive composition is extremely suitable as a wetting agent and dispersant.
摘要翻译：本发明涉及特别包含特定尿素氨基甲酸酯的添加剂组合物的制备方法。添加剂组合物非常适合作为润湿剂和分散剂。

3. 发明授权

US3661857A Polymeric compositions 失效
标题翻译：聚合物组合物
公开(公告)号：US3661857A
公开(公告)日：1972-05-09
申请号：US3661857D
申请日：1970-04-13
申请人： MONSANTO CO
发明人： KERST AL F
IPC分类号： C08G18/83 , C08K5/5373 , C08G22/16 , C08F45/54 , C08G51/54
CPC分类号： C08G18/836 , C08K5/5373
摘要： A POLYMER COMPRISING A REACTIVE HYDROGEN CONTAINING MATERIAL SUCH AS POLYURETHANE, COPOLYMERIZED WITH SUBSTITUTED EPOXY ETHANE POLYPHOSPHONATE HAVING THE FORMULA

2-X,2-Y,3,3-BIS((R-O-)2-P(=O)-)OXIRANE

WHEREIN R IS HYDROGEN OR AN ORGANIC RADICAL AND X AND Y ARE HEREINAFTER DEFINED.

4. 发明申请

US20180346656A1 FUNCTIONALIZED FLAME-RETARDANT ACONITIC ACID-DERIVED MOLECULES 审中-公开
公开(公告)号：US20180346656A1
公开(公告)日：2018-12-06
申请号：US15611313
申请日：2017-06-01
申请人： International Business Machines Corporation
发明人： Sarah K. Czaplewski , Brandon M. Kobilka , Joseph Kuczynski , Jason T. Wertz , Jing Zhang
IPC分类号： C08G81/02 , C08G18/83 , C09J9/00 , C09J175/04 , C09J187/00 , H05K1/03
CPC分类号： C08G81/027 , C07C69/003 , C07C69/007 , C07F9/091 , C07F9/093 , C07F9/113 , C07F9/1411 , C07F9/1412 , C08G18/836 , C08K5/0066 , C08K5/521 , C08K5/524 , C08L2201/02 , C08L2666/84 , C09J9/00 , C09J175/04 , C09J187/005 , C09J2203/326 , C09J2453/00 , C09J2475/00 , H05K1/032
摘要： A functionalized flame-retardant aconitic acid-derived molecule, a process for forming a flame-retardant polymer, and an article of manufacture comprising a material that contains a functionalized flame-retardant aconitic acid-derived molecule are disclosed. The functionalized flame-retardant aconitic acid-derived molecule can have at least one phosphoryl or phosphonyl moiety with allyl functional groups, epoxy functional groups, propylene carbonate functional groups, or functionalized thioether substituents. The process for forming the flame-retardant polymer can include reacting an aconitic acid derivative with a flame-retardant phosphorus-based molecule to form a functionalized flame-retardant aconitic acid-derived molecule, and combining the functionalized flame-retardant aconitic acid-derived molecule with a polymer. The material in the article of manufacture can be a resin, plastic, polymer, or adhesive, and the article of manufacture can further comprise an electronic component.

5. 发明申请

US20110305872A1 NON-FOULING, ANTI-MICROBIAL, ANTI-THROMBOGENIC GRAFT-FROM COMPOSITONS 有权
标题翻译：抗微生物，抗细菌免疫组织化学
公开(公告)号：US20110305872A1
公开(公告)日：2011-12-15
申请号：US13156677
申请日：2011-06-09
申请人： Jun Li , Zheng Zhang , Chad C. Huval , Michael A. Bouchard , Arthur J. Coury , Christopher R. Loose
发明人： Jun Li , Zheng Zhang , Chad C. Huval , Michael A. Bouchard , Arthur J. Coury , Christopher R. Loose
IPC分类号： B32B3/00 , D03D15/00 , D04H13/00 , B05D3/10
CPC分类号： C08F255/02 , A61L29/06 , A61L29/085 , A61L33/0088 , C08F291/00 , C08G18/836 , C08G64/42 , C08G77/38 , C08J7/16 , C08J7/18 , C08J2323/12 , C08J2369/00 , C08J2383/04 , C08J2433/14 , Y10T428/24355 , Y10T428/265 , Y10T442/30 , Y10T442/60 , C08F220/00
摘要： A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 μg/mL fibrinogen derived from human plasma containing 1.4 μg/mL I-125 radiolabeled fibrinogen.
摘要翻译：一种用于制备和产生的制品的方法，包括具有表面，表面下面的体积的基材和在基材表面上的接枝聚合物层，基底表面和接枝聚合物层的组合，构成具有在纤维蛋白原结合测定中纤维蛋白原吸附量小于约125ng / cm 2，其中将修饰的表面在37℃下在70μg/ mL来自含有1.4μg/ mL I-125放射性标记的纤维蛋白原的人血浆的纤维蛋白原中温育60分钟。

6. 发明申请

US20020123599A1 Derivatized polyurethane compositions which exhibit enhanced stability in biological systems and methods of making the same 失效
标题翻译：在生物系统中表现出增强的稳定性的衍生的聚氨酯组合物及其制备方法
公开(公告)号：US20020123599A1
公开(公告)日：2002-09-05
申请号：US09985316
申请日：2001-11-02
发明人： Robert J. Levy , Ivan Alferiev
IPC分类号： C08G018/28
CPC分类号： C08G18/4854 , C08G18/6674 , C08G18/836
摘要： The invention relates to methods of making polyurethane derivatives which can be readily further derivatized using stabilizing agents such as anti-calcification agents, anti-thrombogenesis agents, and chemical and mechanical degradation-inhibiting agents. The invention also includes methods of making polyurethane derivatives so further derivatized and to polyurethanes derivatives made using such methods.
摘要翻译：本发明涉及制备聚氨酯衍生物的方法，其可以使用稳定剂如抗钙化剂，抗血栓形成剂和化学和机械降解抑制剂容易地进一步衍生化。本发明还包括制备如此进一步衍生的聚氨酯衍生物和使用这些方法制备的聚氨酯衍生物的方法。

7. 发明授权

US5914072A Phosphoric esters 失效
标题翻译：磷酸酯
公开(公告)号：US5914072A
公开(公告)日：1999-06-22
申请号：US691317
申请日：1996-08-02
申请人： Michael Zirnstein , Jorg Schroder , Robert Kreuzer
发明人： Michael Zirnstein , Jorg Schroder , Robert Kreuzer
IPC分类号： B01F17/00 , B01F17/14 , B01F17/52 , C07F9/09 , C08G18/32 , C08G18/50 , C08G18/83 , C08G63/692 , C08K5/52 , C08K5/521 , C09B67/20 , C09B67/46 , C09D7/02 , C09D7/12 , C09D11/02 , C09D17/00
CPC分类号： B01F17/0064 , C07F9/09 , C08G18/3271 , C08G18/5021 , C08G18/836 , C08G63/692 , C09B67/0085 , C09D17/00 , C09D7/02 , Y10S516/908
摘要： Phosphoric esters obtained bya) reacting a mono-, oligo- or polyamine with an alkylene oxide or alkylene carbonate to give an amino alcohol or amino mono-, oligo-, or polyether alcohol, from 50 to 100% of the alkoxylatable NH groups of the amine being alkoxylated,b) reacting the resulting amino (ether) alcohol with a hydroxycarboxylic acid or a dicarboxylic acid and a diol to give a mono-, oligo- or polyester, or reacting it with a diisocyanate and a diol to give a di-, oligo- or polyurethane, from 50 to 100% of the terminal hydroxyl groups in the amino (ether) alcohol being esterified or converted into urethane groups, andc) reacting the resulting amino (ether) ester or urethane with a phosphorus compound which forms phosphoric esters, from 5 to 100% of the terminal hydroxyl groups in the amino (ether) ester or urethane being converted into phosphoric ester groups, and the phosphorus atoms being mono- and/or di- and, if appropriate, tri-esterified,preparation of the phosphoric esters, and their use as dispersants for solids.
摘要翻译：通过以下方法获得的磷酸酯：a）使单 - ，多 - 或多胺与烯化氧或碳酸亚烃酯反应，得到氨基醇或氨基单 - ，低聚 - 或聚醚醇，50〜100％的可烷氧基NH基团所述胺被烷氧基化，b）使得到的氨基（醚）醇与羟基羧酸或二羧酸和二醇反应，得到单 - ，寡 - 或聚酯，或者使其与二异氰酸酯和二醇反应，得到二 - ，寡聚或聚氨酯，氨基（醚）醇中的50〜100％的末端羟基被酯化或转化为氨基甲酸酯基，和c）使得到的氨基（醚）酯或氨基甲酸酯与磷化合物反应，形成磷酸酯，氨基（醚）酯或氨基甲酸酯中的末端羟基的5至100％转化为磷酸酯基，磷原子为单 - 和/或二 - 并且如果合适的话，三酯化，磷酸盐的制备以及它们作为固体分散剂的用途。

8. 发明授权

US5453467A Polymer treatments 失效
标题翻译：聚合物处理
公开(公告)号：US5453467A
公开(公告)日：1995-09-26
申请号：US199285
申请日：1994-04-28
申请人： Clement H. Bamford , Kadem G. Al-Lamee , Yiannakis Yianni , Martin C. Wiles , Trevor O. Glasbey
发明人： Clement H. Bamford , Kadem G. Al-Lamee , Yiannakis Yianni , Martin C. Wiles , Trevor O. Glasbey
IPC分类号： A61L27/00 , A61L33/00 , B01D67/00 , C07F9/09 , C07F9/10 , C08F8/40 , C08F283/00 , C08F291/00 , C08G18/28 , C08G18/83 , C08J7/12 , C08J7/16 , C08L75/16 , G02B1/04 , C08F4/52 , C08F255/02 , C08F259/08 , C08F283/04
CPC分类号： B01D67/0093 , A61L33/0088 , C08F283/00 , C08F291/00 , C08F8/40 , C08G18/288 , C08G18/836 , C08J7/16 , C08L75/16 , G02B1/043 , B01D2323/38 , C08J2381/06
摘要： A graft polymer obtainable by grafting a polymer substrate with a compound of formula (I), in which the groups R are the same or different and each is a straight or branched C.sub.1 -C.sub.4 alkyl group; X is an aryl group or a straight or branched C.sub.1 -C.sub.20 alkylene group, optionally containing one or more carbon-carbon double or triple bonds, ether linkages or aryl groups; the aryl groups being unsubstituted or substituted by one or more C.sub.1-4 alkyl groups; n is from 2 to 4; and A is a reactive group, is useful as a biocompatible material in contact lenses, biomedical devices and blood-containing devices. In a preferred embodiment A is a polymerizable group and the graft polymer is produced by radical initiated polymerization of the compound of formula (I) on the substrate which is initiated by a radical-forming group on the substrate.
摘要翻译：通过用式（I）化合物接枝聚合物底物而获得的接枝聚合物，其中基团R相同或不同，并且各自为直链或支链C 1 -C 4烷基; X是任选含有一个或多个碳 - 碳双键或三键的芳基或直链或支链C 1 -C 20亚烷基，醚键或芳基; 芳基是未取代的或被一个或多个C 1-4烷基取代; n为2〜4; 并且A是反应性基团，可用作隐形眼镜，生物医学装置和含血装置中的生物相容性材料。在优选的实施方案中，A是可聚合基团，并且接枝聚合物通过由底物上的自由基形成基团引发的基底上的式（I）化合物的自由基引发聚合制备。

9. 发明授权

US4192927A Polyhydroxyl compounds containing phosphonormamidine groups 失效
标题翻译：含羟基脒基的多羟基化合物
公开(公告)号：US4192927A
公开(公告)日：1980-03-11
申请号：US30494
申请日：1979-04-16
申请人： Walter Schafer , Kuno Wagner , Kurt Findeisen
发明人： Walter Schafer , Kuno Wagner , Kurt Findeisen
IPC分类号： C08G18/38 , C08G18/46 , C08G18/50 , C08G18/79 , C08G18/83 , C08G18/06
CPC分类号： C08G18/797 , C08G18/3889 , C08G18/4684 , C08G18/509 , C08G18/836
摘要： The present invention relates to new polyols modified by phosphonoformamidine groups, to a process for the preparation thereof and the use thereof as starting component for the preparation of preferably foamed polyurethane plastics.The process involves (A) reacting diisocyanatocarbodiimides corresponding to the following general formula:OCN--R.sup.2 --N.dbd.C.dbd.N).sub.m R.sup.2 --NCOat a temperature of from about 25 to 130.degree. C., optionally in the presence of an inert solvent, with polyhydroxyl compounds corresponding to the following general formula:A--OH).sub.nin an OH/NCO-ratio of from 1.2:1 to 30:1 to form a polyhydroxyl compound containing carbodiimide groups and (B) completely or partially reacting the carbodiimide groups remaining in the product of step (A) by means of a basic catalyst at a temperature of from 25 to 150.degree. C., optionally in the presence of an inert solvent, with a phosphite corresponding to the following general formula: ##STR1## to form phosphonoformamidine groups, and (C) distilling off the inert solvent, if used; whereinm represents a number of from 1 to 10, andR.sup.1 represents a C.sub.1 -C.sub.18 aliphatic, C.sub.4 -C.sub.15 cycloaliphatic or C.sub.6 -C.sub.15 aromatic or araliphatic radical which may optionally contain a double bond and/or be branched and which may optionally be substituted by a group selected from the group of hydroxyl or trifluoromethyl groups, fluorine, chlorine, bromine or iodine;R.sup.2 represents a divalent aliphatic, cycloaliphatic, aromatic or araliphatic radical having from 4 to 25 carbon atoms obtained by removing the isocyanate groups from a diisocyanate;A represents an n-valent radical of the type obtained by removing the hydroxyl groups from a polyhydroxyl compound having a molecular weight of from 62 to 6000; andn represents an integer of from 2 to 8.
摘要翻译：本发明涉及通过膦酰基脒基改性的新的多元醇，其制备方法及其作为制备优选泡沫聚氨酯塑料的起始组分的用途。该方法包括（A）在约25至130℃的温度下任选在惰性溶剂存在下，使对应于下列通式的二异氰酸酯碳二亚胺与OCN-R2-N = C = N）mR2-NCO反应，与OH / NCO比为1.2:1至30:1的对应于以下通式的多羟基化合物：A-OH）n以形成含有碳二亚胺基团的多羟基化合物和（B）使碳二亚胺基团完全或部分反应通过碱性催化剂在25至150℃的温度下，任选在惰性溶剂存在下，残留在步骤（A）的产物中，其中亚磷酸酯对应于以下通式：形成膦酰基脒基，和（C）蒸出惰性溶剂（如果使用）其中m表示1-10的数，R1表示C1-C18脂族，C4-C15脂环族或C6-C15芳族或芳脂族基，其可以任选地含有双键和/或被支化并且可任选被取代通过选自羟基或三氟甲基的基团，氟，氯，溴或碘; R2表示通过从二异氰酸酯中除去异氰酸酯基而获得的具有4至25个碳原子的二价脂族，脂环族，芳族或芳脂族基团; A表示通过从分子量为62〜6000的多羟基化合物除去羟基得到的n价基团; n表示2〜8的整数。

10. 发明授权

US4174435A Polyhydroxyl compounds containing phosphonoformamidine groups prepared from diisocyanatocarbodiimides, polyhdroxyl compounds and a phosphite 失效
标题翻译：含有由二异氰酸酯碳二亚胺，多羟基化合物和亚磷酸酯制备的膦酰基脒基的多羟基化合物
公开(公告)号：US4174435A
公开(公告)日：1979-11-13
申请号：US889329
申请日：1978-03-23
申请人： Walter Schafer , Kuno Wagner , Kurt Findeisen
发明人： Walter Schafer , Kuno Wagner , Kurt Findeisen
IPC分类号： C08G18/38 , C08G18/46 , C08G18/50 , C08G18/79 , C08G18/83 , C08G18/06
CPC分类号： C08G18/836 , C08G18/3889 , C08G18/4684 , C08G18/509 , C08G18/797
摘要： The present invention relates to new polyols modified by phosphonoformamidine groups, to a process for the preparation thereof and the use thereof as starting component for the preparation of preferably foamed polyurethane plastics.The process involves (A) reacting diisocyanatocarbodiimides corresponding to the following general formula:OCN--R.sup.2 --N.dbd.C.dbd.N).sub.m R.sup.2 --NCOwith polyhydroxyl compounds corresponding to the following general formula:A--OH).sub.nto form a polyhydroxyl compound containing carbodiimide groups and (B) reacting the carbodiimide groups remaining in the product of step (A) by means of a basic catalyst with a phosphite corresponding to the following general formula: ##STR1## to form phosphonoformamidine groups wherein m represents a number of from 1 to 10, andR.sup.1 represents a C.sub.1 -C.sub.18 aliphatic, C.sub.4 -C.sub.15 cycloaliphatic or C.sub.6 -C.sub.15 aromatic or araliphatic radical which may optionally contain a double bond and/or be branched and which may optionally be substituted by a group selected from the group of hydroxyl or trifluoromethyl groups, fluorine, chlorine, bromine or iodine;R.sup.2 represents a divalent aliphatic, cycloaliphatic, aromatic or araliphatic radical having from 4 to 25 carbon atoms obtained by removing the isocyanate groups from a diisocyanate;A represents an n-valent radical of the type obtained by removing the hydroxyl groups from a polyhydroxyl compound having a molecular weight of from 62 to 6000; andn represents an integer of from 2 to 8.
摘要翻译：本发明涉及通过膦酰基脒基改性的新的多元醇，其制备方法及其作为制备优选泡沫聚氨酯塑料的起始组分的用途。该方法包括：（A）使对应于以下通式的二异氰酸酯碳二亚胺：OCN-R2-N = C = N）mR2-NCO与对应于以下通式的多羟基化合物反应：A-OH）n以形成含有碳二亚胺的多羟基化合物（B）使碱性催化剂与步骤（A）的产物中残留的碳二亚胺基与下列通式相对应的亚磷酸酯反应：形成膦酰基脒基，其中m表示1〜 10，并且R 1表示可以任选地含有双键和/或被支化的C 1 -C 18脂族，C 4 -C 15脂环族或C 6 -C 15脂环族或C 6 -C 15芳族或芳脂族基团，并且其可任选地被选自羟基的基团或三氟甲基，氟，氯，溴或碘; R2表示通过从二异氰酸酯中除去异氰酸酯基而获得的具有4至25个碳原子的二价脂族，脂环族，芳族或芳脂族基团; A表示通过从分子量为62〜6000的多羟基化合物除去羟基得到的n价基团; n表示2〜8的整数。

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