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    • 7. 发明授权
    • Elongated cylindrical medicinal tablet having two layers
    • 细长的圆柱形药片,有两层
    • US5460827A
    • 1995-10-24
    • US978638
    • 1992-11-19
    • Richard SandersonRonald Adams
    • Richard SandersonRonald Adams
    • A61J3/10B29C43/00B30B11/08A61K9/20
    • B30B15/32A61J3/10B29C43/006B30B11/085B29C2043/3618
    • An apparatus for forming a generally cylindrical two-layer, vertically-compressed tablet having a longitudinal axis longer than its diameter is provided in which a generally cylindrical die cavity is provided on a die table with the longitudinal axis of the die cavity being vertically disposed. An upper punch provided above the die cavity rides on an upper cam assembly which controls the movement of the upper punch to and from the die cavity. A lower punch provided below the die cavity rides on a lower cam assembly which raises and lowers the lower punch relative to the die cavity. In operation, the lower punch is positioned and a first powder is added in a metered amount to the die cavity. The upper punch then tamps down the first powder within the die cavity. The lower punch is positioned to receive a metered amount of a second powder in the die cavity above the first powder. The powder in the die cavity is compressed by shifting pressure wheels which prevent the powders from adhering to the wall of the die cavity. After the powder is compressed to form a tablet, the tablet is ejected from die cavity and taken out an ejection chute.
    • 提供一种用于形成具有长于其直径的纵向轴线的大致圆柱形的两层垂直压缩片剂的装置,其中在模具台上设置大致圆柱形的模腔,其中模腔的纵向轴线垂直设置。 设置在模腔上方的上冲头骑在上凸轮组件上,上凸轮组件控制上冲头到模腔的移动。 设置在模腔下方的下冲头骑在下凸轮组件上,下凸轮组件相对于模腔升高并降低下冲头。 在操作中,定位下冲头,并将第一粉末以计量的量加入模腔。 上冲头然后将模具腔内的第一粉末压下。 下冲头定位成在第一粉末上方的模腔中接收计量量的第二粉末。 模腔中的粉末通过移动压力轮来压缩,这防止粉末粘附到模腔的壁上。 粉末被压缩形成片剂后,片剂从模腔中排出并取出排出槽。
    • 8. 发明授权
    • Method and apparatus for making two-layer tablets in a twin rotor
pressing machine
    • 在双转子压片机中制作双层片剂的方法和装置
    • US5350548A
    • 1994-09-27
    • US67635
    • 1993-05-26
    • Jurgen HinzpeterIngo SchmidtHelmut Brommrowitz
    • Jurgen HinzpeterIngo SchmidtHelmut Brommrowitz
    • B30B11/08B29C43/20
    • B30B11/005B30B11/085
    • A method of making two-layer tablets or pellets in a twin rotor pressing machine, in which method during a normal manufacturing period powdery or particulate material is fed into die bores of a die rotor so as to form first layers, said first layers are compressed in a first step by plungers synchronously rotating with the die rotor so as to form first layer pressed articles, the two layers within the die bores are compressed in a second step by said plungers so as to obtain two-layer tablets or pellets, and said two-layer tablets or pellets are removed at a main discharge station, and in which method during an inspection period first layer pressed articles removed at an intermediate discharge station or two-layer tablets or pellets removed at said main discharge station are fed to an inspection station, characterized in that during the inspection period said first layers are compressed more than in said first step during the normal manufacturing period before samples thereof are withdrawn at said intermediate discharge station, and in that the second layers are compressed and the resulting second layer pressed articles are fed either to a scrap path or to said inspection station at least after removal of said samples of the first layer pressed articles.
    • 在双转子压制机中制造双层片剂或丸粒的方法,其中在正常制造期间将粉末状或颗粒状材料的方法进料到模具转子的模孔中以形成第一层,所述第一层被压缩 在第一步骤中,柱塞与模具转子同步旋转以形成第一层压制品,模具孔内的两层在第二步中被所述柱塞压缩,以获得双层片剂或丸粒,并且所述 在主放电站移除双层片剂或丸粒,在检查期间,在中间放电站除去的第一层压制物或在所述主放电站除去的两层片剂或丸粒的方法中, 站,其特征在于,在检查期间,在正常制造期间,所述第一层被压缩得比其在所述第一步骤之前的样品被抽出 在所述中间放电站处被拉出,并且第二层被压缩,并且所得到的第二层压制品至少在移除所述第一层压制品的所述样品之后被馈送到废料路径或所述检查站。