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1. 发明授权

US11987784B2 Sampling system and method of using the same 有权
公开(公告)号：US11987784B2
公开(公告)日：2024-05-21
申请号：US17348961
申请日：2021-06-16
申请人： SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION
发明人： Clemens E. Zoellner , Thomas R. Nixon , Jonathon Wheatley
IPC分类号： C12M1/00 , B01L3/00 , B01L3/02 , C12M1/12 , C12M1/26 , G01N1/14
CPC分类号： C12M33/04 , B01L3/0293 , B01L3/502 , B01L13/00 , C12M23/22 , C12M23/28 , C12M23/38 , C12M37/00 , G01N1/14 , B01L2300/042 , B01L2300/168 , B01L2400/0406 , B01L2400/06 , G01N2001/1427
摘要： The present application is directed to a sampling system for sampling a fluid from a vessel, where the sampling system includes a sterile dispenser assembly operatively connected to the vessel, the sterile dispenser assembly including a valve operatively connected to the vessel, a membrane, and a needle, and a detachable sterile sampling container assembly operatively connected to the sterile dispenser assembly, the detachable sterile sampling container assembly including a sampling container, a membrane attached to the sampling container, and a sampling container housing enclosing the sampling container, where the sampling container housing includes a compressible portion having a deflated configuration and an expanded configuration.

2. 发明授权

US11872557B2 Apparatus and method for control of cell processing system 有权
公开(公告)号：US11872557B2
公开(公告)日：2024-01-16
申请号：US17579478
申请日：2022-01-19
申请人： Cellares Corporation
发明人： Tony Biz , Vladimir Azersky , Adam Newton Wold , Brian Alexander Pesch
IPC分类号： B01L1/00 , B01J19/00 , B01L3/00 , C12M3/00 , C12M1/00 , C12M1/36 , A61L2/04 , A61L2/20 , C12N5/00 , A61L2/08
CPC分类号： B01L3/502715 , A61L2/04 , A61L2/20 , A61L2/206 , A61L2/208 , B01J19/004 , B01L13/00 , C12M23/44 , C12M23/50 , C12M41/48 , C12N5/00 , C12N5/0081 , A61L2/08 , A61L2202/11 , A61L2202/122 , A61L2202/123 , A61L2202/14 , B01J2219/0002 , B01J2219/0074 , B01L2200/027 , B01L2300/049
摘要： Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

3. 发明授权

US11826756B2 Fluid connector 有权
公开(公告)号：US11826756B2
公开(公告)日：2023-11-28
申请号：US18141329
申请日：2023-04-28
申请人： Cellares Corporation
发明人： Vladimir Azersky , Fabian Gerlinghaus , Daniele Malleo , Brian Alexander Pesch , Bharat S. Thakkar , Wilson Wai Toy
IPC分类号： B01L3/00 , A61L2/04 , A61L2/20 , A61L2/08 , B01J19/00 , C12M3/00 , C12M1/00 , C12M1/36 , C12N5/00
CPC分类号： B01L3/502715 , A61L2/04 , A61L2/20 , A61L2/206 , A61L2/208 , B01J19/004 , B01L13/00 , C12M23/44 , C12M23/50 , C12M41/48 , C12N5/00 , C12N5/0081 , A61L2/08 , A61L2202/11 , A61L2202/122 , A61L2202/123 , A61L2202/14 , B01J2219/0002 , B01J2219/0074 , B01L2200/027 , B01L2300/049
摘要： Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

4. 发明授权

US11701654B2 Fluid connector 有权
公开(公告)号：US11701654B2
公开(公告)日：2023-07-18
申请号：US17992784
申请日：2022-11-22
申请人： Cellares Corporation
发明人： Vladimir Azersky , Fabian Gerlinghaus , Daniele Malleo , Brian Alexander Pesch , Bharat S. Thakkar , Wilson Wai Toy
IPC分类号： B01L3/00 , A61L2/04 , A61L2/20 , A61L2/08 , B01J19/00 , C12M3/00 , C12M1/00 , C12M1/36 , C12N5/00
CPC分类号： B01L3/502715 , A61L2/04 , A61L2/20 , A61L2/206 , A61L2/208 , B01J19/004 , B01L13/00 , C12M23/44 , C12M23/50 , C12M41/48 , C12N5/00 , C12N5/0081 , A61L2/08 , A61L2202/11 , A61L2202/122 , A61L2202/123 , A61L2202/14 , B01J2219/0002 , B01J2219/0074 , B01L2200/027 , B01L2300/049
摘要： Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

5. 发明公开

US20230149922A1 FLUID CONNECTOR 审中-公开
公开(公告)号：US20230149922A1
公开(公告)日：2023-05-18
申请号：US17992784
申请日：2022-11-22
申请人： Cellares Corporation
发明人： Bharat S. THAKKAR , Fabian GERLINGHAUS , Brian Alexander PESCH
IPC分类号： B01L3/00 , B01J19/00 , C12M3/00 , C12M1/00 , C12M1/36 , A61L2/04 , A61L2/20 , C12N5/00
CPC分类号： B01L3/502715 , B01L13/00 , B01J19/004 , C12M23/44 , C12M23/50 , C12M41/48 , A61L2/04 , A61L2/208 , A61L2/20 , A61L2/206 , C12N5/00 , C12N5/0081 , B01L2200/027 , B01L2300/049 , B01J2219/0002 , B01J2219/0074 , A61L2202/14 , A61L2202/122 , A61L2202/11 , A61L2/08
摘要： Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

6. 发明申请

US20150093786A1 Laboratory apparatus and method of using a laboratory apparatus 审中-公开
标题翻译：实验室仪器和使用实验室仪器的方法
公开(公告)号：US20150093786A1
公开(公告)日：2015-04-02
申请号：US14040419
申请日：2013-09-27
申请人： Eppendorf AG
发明人： Andreas THIEME , Judith LUCKE , Rusbeh GOECKE , Manfred EBERS , Helmut KNOFE , Harald ANDRULAT
IPC分类号： G01N35/00 , B01L7/00 , C12Q1/68
CPC分类号： G01N35/00584 , B01L1/025 , B01L13/00 , B01L13/02 , B01L2200/141 , B01L2300/0627 , B01L2300/0829 , C12Q1/686 , G01N2035/00277 , G01N2035/00316
摘要： The invention is related to a laboratory apparatus and method for the automated processing of liquid samples, in particular for the program controlled handling of liquid samples, having an electronic control device, which is adapted to process a program code for the program controlled processing of fluid samples, at least one processing space for receiving the fluid samples to be processed, at least one electronically controllable sample processing device for performing at least one program controlled process step on at least one sample, which is arranged in the processing space, at least one electronically controllable decontamination device for cleaning at least a part of the processing space, wherein the decontamination device is configured to be controlled by the control device and the control device is configured to digitally control the decontamination device.
摘要翻译：本发明涉及用于液体样品的自动处理的实验室设备和方法，特别是用于液体样品的程序控制处理，其具有电子控制装置，该电子控制装置适于处理程序控制的流体处理程序代码用于接收要处理的流体样品的至少一个处理空间，至少一个电子可控样品处理装置，用于在布置在处理空间中的至少一个样品上执行至少一个程序控制的处理步骤，至少一个电子可控净化装置，其用于清洁处理空间的至少一部分，其中所述净化装置被配置为由所述控制装置控制，并且所述控制装置被配置为数字地控制所述去污装置。

7. 发明申请

US20100300978A1 DEVICE, SYSTEM AND METHOD FOR WASHING AND ISOLATING MAGNETIC PARTICLES IN A CONTINOUS FLUID FLOW 审中-公开
标题翻译：用于在连续流体流中洗涤和分离磁性颗粒的装置，系统和方法
公开(公告)号：US20100300978A1
公开(公告)日：2010-12-02
申请号：US12679013
申请日：2007-09-19
申请人： Qasem Ramadan , Liang Zhu , Hongmiao Ji , Wen-Tso Liu
发明人： Qasem Ramadan , Liang Zhu , Hongmiao Ji , Wen-Tso Liu
IPC分类号： B03C1/02
CPC分类号： G01N33/54326 , B01L9/52 , B01L13/00 , B03C1/0332 , B03C1/288 , B03C2201/18
摘要： A device for washing and isolating magnetic particles from a continuous fluid flow in at least one fluidic channel having an inlet at one end and an outlet at another end, said device comprising at least one magnetic source carrier arranged proximate to the at least one fluidic channel. The at least one magnetic source carrier is moveable between a first position and a second position. The at least one magnetic source carrier comprises at least one first magnetic source, wherein a movement of the at least one magnetic source carrier to the first position places the at least one first magnetic source at a first spatial location along the at least one fluidic channel such that said at least one first magnetic source generates a maxima magnetic field at said first spatial location that attracts the magnetic particles from the continuous fluid flow and assembles said magnetic particles at said first spatial location. A movement of the at least one magnetic source carrier to the second position places the at least one first magnetic source distal from the first spatial location such that said magnetic field at said first spatial location is at a minima and the magnetic particles disperse from said first spatial location.
摘要翻译：一种用于在至少一个具有一端的入口和另一端的出口的流体通道中从连续的流体流中洗涤和分离磁性颗粒的装置，所述装置包括至少一个靠近所述至少一个流体通道布置的磁源载体。所述至少一个磁源载体可在第一位置和第二位置之间移动。所述至少一个磁源载体包括至少一个第一磁源，其中所述至少一个磁源载体到所述第一位置的移动将所述至少一个第一磁源置于沿所述至少一个流体通道的第一空间位置使得所述至少一个第一磁源在所述第一空间位置产生最大磁场，其吸引来自连续流体流的磁性颗粒，并在所述第一空间位置组装所述磁性颗粒。至少一个磁源载体到第二位置的移动将至少一个第一磁源远离第一空间位置放置，使得所述第一空间位置处的所述磁场处于最小值，并且磁性颗粒从所述第一空间位置分散空间位置。

8. 发明公开

US20230415154A1 FLUID CONNECTOR 审中-公开
公开(公告)号：US20230415154A1
公开(公告)日：2023-12-28
申请号：US18244047
申请日：2023-09-08
申请人： Cellares Corporation
发明人： Brian Alexander PESCH , Fabian GERLINGHAUS , Nicholas Scott REIMNITZ
IPC分类号： B01L3/00 , B01J19/00 , C12M3/00 , C12M1/00 , C12M1/36 , A61L2/04 , A61L2/20 , C12N5/00
CPC分类号： B01L3/502715 , A61L2/08 , B01J19/004 , C12M23/44 , C12M23/50 , C12M41/48 , A61L2/04 , A61L2/208 , A61L2/20 , A61L2/206 , C12N5/00 , C12N5/0081 , B01L2200/027 , B01L2300/049 , B01J2219/0002 , B01J2219/0074 , A61L2202/14 , A61L2202/122 , A61L2202/11 , B01L13/00
摘要： Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

9. 发明授权

US11786896B2 Fluid connector 有权
公开(公告)号：US11786896B2
公开(公告)日：2023-10-17
申请号：US17849422
申请日：2022-06-24
申请人： Cellares Corporation
发明人： Bharat S. Thakkar , Fabian Gerlinghaus , Brian Alexander Pesch
IPC分类号： B01L3/00 , B01J19/00 , C12M3/00 , C12M1/00 , C12M1/36 , A61L2/04 , A61L2/20 , C12N5/00 , A61L2/08
CPC分类号： B01L3/502715 , A61L2/04 , A61L2/20 , A61L2/206 , A61L2/208 , B01J19/004 , B01L13/00 , C12M23/44 , C12M23/50 , C12M41/48 , C12N5/00 , C12N5/0081 , A61L2/08 , A61L2202/11 , A61L2202/122 , A61L2202/123 , A61L2202/14 , B01J2219/0002 , B01J2219/0074 , B01L2200/027 , B01L2300/049
摘要： Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

10. 发明公开

US20230158496A1 FLUID LAYING DEVICE, FLUID LAYING METHOD, FLUID LAYING SYSTEM, COMPOSITE DEVICE, AND FLUID PASSAGE DEVICE 审中-公开
公开(公告)号：US20230158496A1
公开(公告)日：2023-05-25
申请号：US17919341
申请日：2020-04-20
申请人： MGI Tech Co., Ltd.
发明人： XINGYE CUI , JOON MO YANG , HONG XU , XIANGKUN SUI , Greg Bogdan
IPC分类号： B01L3/00 , B01L9/00 , C12M1/00
CPC分类号： B01L3/502738 , B01L3/502715 , B01L9/527 , C12M1/00 , B01L13/00 , B01L2200/027 , B01L2200/028 , B01L2200/0689 , B01L2300/0861 , B01L2300/0877 , B01L2400/0487 , B01L2400/0622
摘要： A fluid laying device includes a manifold block. The manifold block defines a first channel, and also defines a first fluid inlet, a first fluid outlet, and several carrier interfaces. Each carrier interface has a first hole connecting one of a channel inlet and channel outlets of the flow cell carrier. The manifold block is provided with an inlet valve device, a bypass valve device, and outlet valve devices. The inlet valve device and the outlet valve devices are one-to-one corresponding to the carrier interfaces, and disposed on a fluid path from the corresponding carrier interface to the first channel. The first channel includes a first section and a second section. A bypass valve device is between the first and second sections to control connection and disconnection between the first and second sections. The inlet valve device connects the first section, and the outlet valve devices connect the second section.

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