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1. 发明申请

US20140308325A1 HEMOSTATIC SPONGE 审中-公开
标题翻译： HEMOSTATIC海绵
公开(公告)号：US20140308325A1
公开(公告)日：2014-10-16
申请号：US14184543
申请日：2014-02-19
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： Hans Christian Hedrich , Joris Hoefinghoff
IPC分类号： A61L15/26 , A61L15/32 , A61L15/42
CPC分类号： A61L15/44 , A61F13/00063 , A61F2013/0011 , A61L15/18 , A61L15/225 , A61L15/26 , A61L15/325 , A61L15/425 , A61L24/0036 , A61L24/0094 , A61L2300/232 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/606 , A61L2400/04 , A61L2420/02 , C12Y304/21005
摘要： The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.
摘要翻译：本发明提供一种止血多孔复合海绵，其包括i）生物材料的基质和ii）包含反应性基团的一种亲水性聚合物组分，其中i）和ii）彼此相关联，使得保留聚合物组分的反应性，其中相关联的意思是将所述聚合物组分涂覆在生物材料的所述基质的表面上，或者所述基质用所述聚合物材料或两者浸渍。

2. 发明授权

US4872450A Wound dressing and method of forming same 失效
标题翻译：伤口敷料及其形成方法
公开(公告)号：US4872450A
公开(公告)日：1989-10-10
申请号：US759628
申请日：1985-07-26
申请人： Eric D. Austad
发明人： Eric D. Austad
IPC分类号： A61F5/058 , A61F13/00 , A61F13/02 , A61F13/04
CPC分类号： A61F13/04 , A61F13/00021 , A61F13/00063 , A61F5/058 , A61F2013/0011 , A61F2013/00157 , A61F2013/00519 , A61F2013/00536 , A61F2013/00625 , A61F2013/00634 , A61F2013/0074 , A61F2013/0091 , Y10S602/90
摘要： A conforming foam wound dressing and the method of forming it, wherein an enclosure is placed over the wounded area, an opening is formed in the enclosure and medical grade foam is injected through the opening. The foam is dispensible from a pressurized container and dries rapidly to form a solid body.
摘要翻译：符合要求的泡沫伤口敷料及其形成方法，其中将外壳放置在伤口区域上方，在外壳中形成开口，并且医疗级泡沫通过开口注入。泡沫从加压容器中是可分配的并且迅速干燥以形成固体。

3. 发明申请

US20100286591A1 Dispensing Device and Method for Forming Material 失效
标题翻译：分配装置及成型方法
公开(公告)号：US20100286591A1
公开(公告)日：2010-11-11
申请号：US12823205
申请日：2010-06-25
申请人： Ronald Alan Coffee
发明人： Ronald Alan Coffee
IPC分类号： A61B17/03 , A61N1/30 , A61B18/18
CPC分类号： A61F13/00063 , A61F13/069 , A61F13/36 , A61F2013/0011 , A61F2013/00157 , A61F2013/00519 , A61F2013/0091 , A61F2013/00914 , A61F2013/00923 , A61F2013/00927 , A61M15/0003 , A61M15/0011 , A61M15/02 , B05B1/044 , B05B1/06 , B05B1/14 , B05B5/0255 , B05B5/1691 , B05B7/061 , B05B12/1472 , D01D5/0084 , D01F1/10
摘要： A dispensing device and method for forming a least partially solid or gel-like material from a liquid. At least one liquid issuing from an outlet is subjected to an electric field causing the liquid to form at least one electrically charged jet which, after formation, forms a fiber (F) or breaks up into fiber fragments (FF) or particles (D). The thus formed at least partially solid or gel-like material may be directly deposited, by virtue of the energy in the electrical field, onto a surface area, for example an area of skin enabling, for example, formation of a dressing for a wound or burn which is of high specific area and extremely absorbent. A biologically active ingredient such as a pharmaceutical ingredient or biological matter such as DNA may be incorporated into the fibers (F), fragments (FF) or particles (D). Fibrils, particles or microcapsules incorporating a biologically active ingredient may be supplied for oral or nasal administration to an animal such as a human being.
摘要翻译：一种用于从液体形成至少部分固体或凝胶状材料的分配装置和方法。从出口排出的至少一种液体经受电场，导致液体形成至少一个带电的射流，其在形成后形成纤维（F）或分解成纤维碎片（FF）或颗粒（D）。由此形成的至少部分固体或凝胶状材料可以通过电场中的能量直接沉积到表面区域上，例如能够形成伤口敷料的皮肤区域或具有高比表面积和极度吸收性的燃烧。生物活性成分如药物成分或生物物质如DNA可以并入纤维（F），碎片（FF）或颗粒（D）中。可以向动物如人提供包含生物活性成分的原纤维，颗粒或微胶囊用于口服或鼻腔给药。

4. 发明授权

US07193124B2 Method for forming material 失效
标题翻译：材料成型方法
公开(公告)号：US07193124B2
公开(公告)日：2007-03-20
申请号：US09758716
申请日：2001-01-11
申请人： Ronald Alan Coffee
发明人： Ronald Alan Coffee
IPC分类号： A61F13/00
CPC分类号： A61F13/00995 , A61F13/00085 , A61F13/36 , A61F2013/0011 , A61F2013/00157 , A61F2013/00519 , A61F2013/0091 , A61F2013/00914 , A61F2013/00927 , A61M15/0003 , A61M15/0011 , A61M15/02 , B05B1/044 , B05B1/06 , B05B1/14 , B05B5/0255 , B05B5/1691 , B05B7/061 , B05B12/1472 , D01D5/0084 , D01F1/10
摘要： A dispensing device and method for forming a least partially solid or gel-like material from a liquid. At least one liquid issuing from an outlet is subjected to an electric field causing the liquid to form at least one electrically charged jet which, after formation, forms a fiber (F) or breaks up into fiber fragments (FF) or particles (D). The thus formed at least partially solid or gel-like material may be directly deposited, by virtue of the energy in the electrical field, onto a surface area, for example an area of skin enabling, for example, formation of a dressing for a wound or burn which is of high specific area and extremely absorbent. A biologically active ingredient such as a pharmaceutical ingredient or biological matter such as DNA may be incorporated into the fibers (F), fragments (FF) or particles (D). Fibrils, particles or microcapsules incorporating a biologically active ingredient may be supplied for oral or nasal administration to an animal such as a human being.
摘要翻译：一种用于从液体形成至少部分固体或凝胶状材料的分配装置和方法。从出口排出的至少一种液体经受电场，导致液体形成至少一个带电的射流，其在形成后形成纤维（F）或分解成纤维碎片（FF）或颗粒（D）。由此形成的至少部分固体或凝胶状材料可以通过电场中的能量直接沉积到表面区域上，例如能够形成伤口敷料的皮肤区域或具有高比表面积和极度吸收性的燃烧。生物活性成分如药物成分或生物物质如DNA可以并入纤维（F），碎片（FF）或颗粒（D）中。可以向动物如人提供包含生物活性成分的原纤维，颗粒或微胶囊用于口服或鼻腔给药。

5. 发明申请

US20010003148A1 Dispensing device and method for forming material 失效
标题翻译：点胶装置及成型方法
公开(公告)号：US20010003148A1
公开(公告)日：2001-06-07
申请号：US09758716
申请日：2001-01-11
发明人： Ronald Alan Coffee
IPC分类号： A61F013/00
CPC分类号： A61F13/00995 , A61F13/00085 , A61F13/36 , A61F2013/0011 , A61F2013/00157 , A61F2013/00519 , A61F2013/0091 , A61F2013/00914 , A61F2013/00927 , A61M15/0003 , A61M15/0011 , A61M15/02 , B05B1/044 , B05B1/06 , B05B1/14 , B05B5/0255 , B05B5/1691 , B05B7/061 , B05B12/1472 , D01D5/0084 , D01F1/10
摘要： A dispensing device and method for forming a least partially solid or gel-like material from a liquid. At least one liquid issuing from an outlet is subjected to an electric field causing the liquid to form at least one electrically charged jet which, after formation, forms a fiber (F) or breaks up into fiber fragments (FF) or particles (D). The thus formed at least partially solid or gel-like material may be directly deposited, by virtue of the energy in the electrical field, onto a surface area, for example an area of skin enabling, for example, formation of a dressing for a wound or burn which is of high specific area and extremely absorbent. A biologically active ingredient such as a pharmaceutical ingredient or biological matter such as DNA may be incorporated into the fibers (F), fragments (FF) or particles (D). Fibrils, particles or microcapsules incorporating a biologically active ingredient may be supplied for oral or nasal administration to an animal such as a human being.
摘要翻译：一种用于从液体形成至少部分固体或凝胶状材料的分配装置和方法。从出口排出的至少一种液体经受电场，导致液体形成至少一个带电的射流，其在形成后形成纤维（F）或分解成纤维碎片（FF）或颗粒（D）。由此形成的至少部分固体或凝胶状材料可以通过电场中的能量直接沉积到表面区域上，例如能够形成伤口敷料的皮肤区域或具有高比表面积和极度吸收性的燃烧。生物活性成分如药物成分或生物物质如DNA可以并入纤维（F），碎片（FF）或颗粒（D）中。可以向动物如人提供包含生物活性成分的原纤维，颗粒或微胶囊用于口服或鼻腔给药。

6. 发明授权

US08703170B2 Hemostatic sponge 有权
标题翻译：止血海绵
公开(公告)号：US08703170B2
公开(公告)日：2014-04-22
申请号：US13082114
申请日：2011-04-07
申请人： Hans Christian Hedrich , Joris Hoefinghoff
发明人： Hans Christian Hedrich , Joris Hoefinghoff
IPC分类号： A61F13/00
CPC分类号： A61L15/44 , A61F13/00063 , A61F2013/0011 , A61L15/18 , A61L15/225 , A61L15/26 , A61L15/325 , A61L15/425 , A61L24/0036 , A61L24/0094 , A61L2300/232 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/606 , A61L2400/04 , A61L2420/02 , C12Y304/21005
摘要： The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.
摘要翻译：本发明提供一种止血多孔复合海绵，其包括i）生物材料的基质和ii）包含反应性基团的一种亲水性聚合物组分，其中i）和ii）彼此相关联，使得保留聚合物组分的反应性，其中相关联的意思是将所述聚合物组分涂覆在生物材料的所述基质的表面上，或者所述基质用所述聚合物材料或两者浸渍。

7. 发明申请

US20120009275A1 In-situ forming hydrogel wound dressings containing antimicrobial agents 有权
标题翻译：含抗微生物剂的原位形成水凝胶伤口敷料
公开(公告)号：US20120009275A1
公开(公告)日：2012-01-12
申请号：US13135247
申请日：2011-06-28
申请人： Bruktawit T. Asfaw , John C. Jackson , Zhihua Lu , Xiaowen Zhai , Sameer Shums , Thomas Hirt , Xianbo Hu , Claude-Raymond René
发明人： Bruktawit T. Asfaw , John C. Jackson , Zhihua Lu , Xiaowen Zhai , Sameer Shums , Thomas Hirt , Xianbo Hu , Claude-Raymond René
IPC分类号： A01N59/16 , A01P1/00
CPC分类号： A01N59/16 , A01N25/04 , A61F2013/0011
摘要： A composition comprising a macromer that can be in situ polymerized into a hydrogel wound dressing directly on a wound and one or more antimicrobial agents intended to achieve bacteriostasis and/or be bacteriocidal. The antimicrobial agent is released upon application and trapped in the hydrogel upon its formation and also released over a period of time into the wound.
摘要翻译：包含大分子单体的组合物，其可原位聚合成直接在伤口上的水凝胶伤口敷料和一种或多种旨在实现抑菌和/或具有杀菌作用的抗微生物剂。抗微生物剂在施用时释放并在其形成时被捕获在水凝胶中，并且在一段时间内释放到伤口中。

8. 发明申请

US20090324713A1 SPRAY-ON, NON-WOVEN FABRIC SYSTEM AND MULTILAYER WOUND COVERINGS 审中-公开
标题翻译：喷涂，非织造织物系统和多层绕线罩
公开(公告)号：US20090324713A1
公开(公告)日：2009-12-31
申请号：US12164405
申请日：2008-06-30
申请人： John T. Ulman , Charlene Cheuk Ng
发明人： John T. Ulman , Charlene Cheuk Ng
IPC分类号： A61K9/00 , A61F13/00 , A61P17/02
CPC分类号： A61F13/00051 , A61F13/00017 , A61F2013/0011 , A61F2013/0017 , A61F2013/00536 , A61K9/0014 , A61K9/7015 , A61L15/00 , A61L26/0076
摘要： The invention is directed to a spray-on, non-woven fabric system and multilayer wound coverings for promoting wound healing, where the fabric system includes a first spray-on composition including a non-volatile carrier for keeping the wound moist and a second spray-on composition for covering the first composition and protecting the wound which includes fibers, a volatile carrier, and a binding agent, and where the multilayer wound covering includes a first layer formed from the first spray-on composition and a second layer covering the first layer, the second layer formed from the second spray-on composition.
摘要翻译：本发明涉及用于促进伤口愈合的喷涂非织造织物系统和多层伤口覆盖物，其中织物系统包括第一喷涂组合物，其包括用于保持伤口潮湿的非挥发性载体和第二喷雾 - 用于覆盖第一组合物并保护包括纤维，挥发性载体和粘合剂的伤口的组合物，并且其中多层缠绕覆盖物包括由第一喷射组合物形成的第一层和覆盖第一喷涂组合物的第二层层，由第二喷涂组合物形成的第二层。

9. 发明申请

US20080119772A1 Dispensing device and method for forming material 审中-公开
标题翻译：点胶装置及成型方法
公开(公告)号：US20080119772A1
公开(公告)日：2008-05-22
申请号：US11711378
申请日：2007-02-27
申请人： Ronald Alan Coffee
发明人： Ronald Alan Coffee
IPC分类号： A61F13/00
CPC分类号： A61F13/00063 , A61F13/069 , A61F13/36 , A61F2013/0011 , A61F2013/00157 , A61F2013/00519 , A61F2013/0091 , A61F2013/00914 , A61F2013/00923 , A61F2013/00927 , A61M15/0003 , A61M15/0011 , A61M15/02 , B05B1/044 , B05B1/06 , B05B1/14 , B05B5/0255 , B05B5/1691 , B05B7/061 , B05B12/1472 , D01D5/0084 , D01F1/10
摘要： A dispensing device and method for forming a least partially solid or gel-like material from a liquid. At least one liquid issuing from an outlet is subjected to an electric field causing the liquid to form at least one electrically charged jet which, after formation, forms a fiber (F) or breaks up into fiber fragments (FF) or particles (D). The thus formed at least partially solid or gel-like material may be directly deposited, by virtue of the energy in the electrical field, onto a surface area, for example an area of skin enabling, for example, formation of a dressing for a wound or burn which is of high specific area and extremely absorbent. A biologically active ingredient such as a pharmaceutical ingredient or biological matter such as DNA may be incorporated into the fibers (F), fragments (FF) or particles (D). Fibrils, particles or microcapsules incorporating a biologically active ingredient may be supplied for oral or nasal administration to an animal such as a human being.
摘要翻译：一种用于从液体形成至少部分固体或凝胶状材料的分配装置和方法。从出口排出的至少一种液体经受电场，导致液体形成至少一个带电的射流，其在形成后形成纤维（F）或分解成纤维碎片（FF）或颗粒（D）。由此形成的至少部分固体或凝胶状材料可以通过电场中的能量直接沉积到表面区域上，例如能够形成伤口敷料的皮肤区域或具有高比表面积和极度吸收性的燃烧。生物活性成分如药物成分或生物物质如DNA可以并入纤维（F），碎片（FF）或颗粒（D）中。可以向动物如人提供包含生物活性成分的原纤维，颗粒或微胶囊用于口服或鼻腔给药。

10. 发明申请

US20160317697A1 HEMOSTATIC SPONGE 审中-公开
标题翻译： HEMOSTATIC海绵
公开(公告)号：US20160317697A1
公开(公告)日：2016-11-03
申请号：US15181280
申请日：2016-06-13
申请人： Baxter International Inc. , Baxter Healthcare SA
发明人： Hans Christian Hedrich , Joris Hoefinghoff
IPC分类号： A61L15/44 , A61F13/00 , A61L15/22 , A61L15/42 , A61L15/18
CPC分类号： A61L15/44 , A61F13/00063 , A61F2013/0011 , A61L15/18 , A61L15/225 , A61L15/26 , A61L15/325 , A61L15/425 , A61L24/0036 , A61L24/0094 , A61L2300/232 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/606 , A61L2400/04 , A61L2420/02 , C12Y304/21005
摘要： The present invention provides a hemostatic porous composite sponge comprising: i) a matrix of a biomaterial; and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.
摘要翻译：本发明提供一种止血多孔复合海绵，其包括i）生物材料的基质和ii）包含反应性基团的一种亲水性聚合物组分，其中i）和ii）彼此相关联，使得保留聚合物组分的反应性，其中所述聚合物组分被涂覆在生物材料的所述基体的表面上，或 - 所述基质用所述聚合物材料浸渍，或 - 两者。

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