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1. 发明授权

US11261414B2 Apparatus for reconfiguration of components in a microphysiological system 有权
公开(公告)号：US11261414B2
公开(公告)日：2022-03-01
申请号：US16348835
申请日：2017-11-14
申请人： Arizona Board of Regents on Behalf of the University of Arizona , Universite du Luxembourg
发明人： Matthew Barrett , Marc Pol Mac Giolla Eain , Paul Wilmes , Frederic Zenhausern
IPC分类号： C12M1/00 , C12M3/06 , C12M3/00 , C12M1/12
摘要： Provided herein is a microphysiological system that may be used in various cell culture applications and biological system studies, that facilitates co-culture, monitoring, and study of functional interactions among different types of cellular and biological materials under various environmental conditions. The system is configured for fast assembly and disassembly, thereby minimizing damage or contamination of the biological materials and environmental conditions inside the system. The system comprises a base, a lid, and a plurality of clamps that are connected to the base and the lid. The base has a recess surface for receiving cell culture support layers. The lid has a stepped surface configured to exert a contact force to a top layer of one or more cell culture support layers during use. The clamp involves an engagement mechanism that generates a contact force allowing for sealing of the cell culture support layers in a manner that minimizes leakage of fluids.

2. 发明授权

US10612053B2 Isolated genes and transgenic organisms for producing biofuels 有权
公开(公告)号：US10612053B2
公开(公告)日：2020-04-07
申请号：US14429287
申请日：2013-09-18
申请人： THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE , UNIVERSITÉ DU LUXEMBOURG , Emilie Muller , Paul Wilmes , Paul S. Keim , John D. Gillece , James M. Schupp , Lance B. Price , David M. Engelthaler
发明人： Emilie Muller , Paul Wilmes , Paul S. Keim , John D. Gillece , James M. Schupp , Lance B. Price , David M. Engelthaler
IPC分类号： C12P7/64
CPC分类号： C12P7/649 , C12P7/6463
摘要： Methods for the production of lipids and biofuels with a culture of Candidatus Microthrix spp. grown on a medium such as wastewater or sewage sludge are provided. The Candidatus Microthrix spp. may be cultured with additional microorganisms that contribute to the accumulation of lipids from the growth medium such as Zoog!oea spp., Rhizobacter spp., Blautia spp., Hydrolatea spp., ODI genera incertae sedis. Further discloses are transformed organisms comprising genes isolated from Candidatus Microthrix parvicella, as well as methods and processes for producing lipids, fatty acids, or biofuels in vitro using the protein products of the isolated genes.

3. 发明授权

US09245810B2 Electrical and opto-electrical characterization of large-area semiconductor devices 有权
标题翻译：大面积半导体器件的电气和光电特性
公开(公告)号：US09245810B2
公开(公告)日：2016-01-26
申请号：US13266948
申请日：2010-04-27
申请人： Phillip Dale , Susanne Siebentritt
发明人： Phillip Dale , Susanne Siebentritt
IPC分类号： G01R31/02 , H01L21/66
CPC分类号： H01L22/14
摘要： The present invention relates to an electrical and/or opto-electrical characterisation method for testing large-area semiconductor devices in production, the method comprising the steps of providing a first electrode and placing it into electrical contact with a contact area of a conducting layer of a semiconductor device; providing a movable electrode assembly, comprising a container holding an electrolyte solution and at least a second electrode; immersing the second electrode into the electrolyte solution; positioning the electrode assembly such that the electrolyte solution places the second electrode into electrical contact with a top surface of the semiconductor device; and scanning the movable electrode assembly relative to the top surface of the semiconductor device while performing electrical measurements. It also relates to a corresponding electrical and/or opto-electrical characterisation device comprising a first electrode, a movable electrode assembly with a container holding an electrolyte solution and a second electrode immersed into it and scanning means.
摘要翻译：本发明涉及一种用于在生产中测试大面积半导体器件的电和/或光电表征方法，该方法包括以下步骤：提供第一电极并将其放置成与导电层的导电层的接触区域半导体器件; 提供可移动电极组件，包括容纳电解质溶液的容器和至少第二电极; 将第二电极浸入电解液中; 定位电极组件使得电解质溶液使第二电极与半导体器件的顶表面电接触; 以及在执行电测量时相对于半导体器件的顶表面扫描可动电极组件。它还涉及相应的电和/或光电表征装置，其包括第一电极，具有容纳电解质溶液的容器的可动电极组件和浸入其中的第二电极和扫描装置。

4. 发明授权

US10768273B2 Orthogonal phase modulation for detection and communication in radar 有权
公开(公告)号：US10768273B2
公开(公告)日：2020-09-08
申请号：US16612223
申请日：2018-05-09
申请人： IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. , UNIVERSITE DU LUXEMBOURG
发明人： Udo Schroder , Hans-Peter Beise , Thiemo Spielmann , Sayed Hossein Dokhanchi
IPC分类号： G01S7/00 , G01S13/32 , G01S13/87 , H04B7/06 , G01S13/931 , G01S7/02
摘要： A method of orthogonal modulation of radar waves of a phase-modulated continuous wave radar system. The method includes selecting an equidistant bi-phased or multi-phased phase-modulation sequence, phase-modulating the continuous radar wave, and transmitting the orthogonal phase-modulated continuous radar wave towards a scene. The method includes generating a detection sequence (s) by applying an outer coding (H) to the phase-modulation sequence, selecting a communication range (C) in the complex number plane, based on the selected phase-modulation, generating a communication sequence (c) having a plurality of sequence members, mapping the communication sequence (c) into the communication range (C) by applying an injective mapping function (Γ) to the sequence members, and calculating a numerical product of members of the detection sequence (s) with members of an image of the mapped communication sequence (c). Phase-modulating the continuous wave of the radar system is carried out according to the calculated numerical products.

5. 发明申请

US20140020738A1 SOLAR CELL, AND PROCESS FOR PRODUCING SOLAR CELL 审中-公开
标题翻译：太阳能电池和生产太阳能电池的方法
公开(公告)号：US20140020738A1
公开(公告)日：2014-01-23
申请号：US14008821
申请日：2012-03-28
申请人： Yasuhiro Aida , Valerie Depredurand , Susanne Siebentritt
发明人： Yasuhiro Aida , Valerie Depredurand , Susanne Siebentritt
IPC分类号： H01L31/032
CPC分类号： H01L31/0322 , H01L31/0749 , Y02E10/541 , Y02P70/521
摘要： A solar cell that can increase open-circuit voltage compared to the conventional solar cell, and as a result, can increase conversion efficiency. The solar cell includes a first absorber layer and a second absorber layer, wherein the first absorber layer is a p-type semiconductor layer containing a Ib group element, a IIIb group element, and a VIb group element and including a peak of luminescence whose half width is not less than 1 meV and not more than 15 meV in a photoluminescence spectrum or a cathodoluminescence spectrum; and the second absorber layer contains a Ib group element, a IIIb group element, and a VIb group element, the composition ratio of the Ib group element to the IIIb group element is not less than 0.1 and less than 1.0, and the second absorber layer is provided on the side of the light entering surface of the first absorber layer.
摘要翻译：与常规太阳能电池相比，可以增加开路电压的太阳能电池，结果可以提高转换效率。太阳能电池包括第一吸收层和第二吸收层，其中第一吸收层是包含Ib族元素，IIIb族元素和VIb族元素的p型半导体层，并且包括其半数的发光峰在光致发光光谱或阴极发光光谱中宽度不小于1meV且不大于15meV; 第二吸收体层含有Ib族元素，IIIb族元素和VIb族元素，Ib族元素与IIIb族元素的组成比为0.1以上且小于1.0，第二吸收体层设置在第一吸收体层的光入射面的一侧。

6. 发明申请

US20120115928A1 MIRNA AND ITS TARGETS RESPECTIVELY THE PROTEINS MADE BASED ON THE TARGETS AS A PROGNOSTIC, DIAGNOSTIC BIOMARKER AND THERAPEUTIC AGENT FOR CANCER 审中-公开
标题翻译： MIRNA及其目标相对于基于目标的蛋白质作为预防，诊断性生物标志物和癌症治疗剂
公开(公告)号：US20120115928A1
公开(公告)日：2012-05-10
申请号：US13260488
申请日：2010-03-26
申请人： Guillaume Vetter , Evelyne Friederich
发明人： Guillaume Vetter , Evelyne Friederich
IPC分类号： A61K31/7088 , A61P25/00 , G01N33/574 , A61P35/00 , C07H21/02 , C07K14/47
CPC分类号： C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2310/3231 , C12N2310/341 , C12N2330/10
摘要： A compound miRNA (miRNA661) (Nr MI0003669 or ENSG00000207574) the sequence of the mature miRNA-661 being 51-ugccugggucucuggccugcgcgu-74 for use as a medicament in the in the treatment and/or the diagnosis of cancer, neuronal disease and infection.
摘要翻译：复合miRNA（miRNA661）（Nr MI0003669或ENSG00000207574），成熟miRNA-661的序列是51 -ugugucucucuccuccgcgu-74，用作治疗和/或诊断癌症，神经元疾病和感染的药物。

7. 发明公开

US20230393945A1 RADIATION INDUCED FAULT SELF-PROTECTING CIRCUITS AND ARCHITECTURES 审中-公开
公开(公告)号：US20230393945A1
公开(公告)日：2023-12-07
申请号：US18269068
申请日：2022-01-28
申请人： UNIVERSITE DU LUXEMBOURG
发明人： Rafal GRACZYK , Marcus VÖLP , Paulo ESTEVES-VERÍSSIMO
IPC分类号： G06F11/14 , G06F11/07
CPC分类号： G06F11/1438 , G06F11/0793 , G06F2201/805
摘要： The present invention pertains to electronics (circuits and systems comprising such circuits, specifically like tiled multi- and manycore systems) for use in increased radiation environments. The invention provides (operating) methods and apparatuses (systems) for mitigating radiation effects in the (main) circuits (also denoted tiles) defining these apparatuses by adapting those or providing those with additional building blocks, enabling use of a depowering technique The invention also mitigates radiation effects in those building blocks (circuits or subcircuits) of the apparatuses themselves. The invention enables to retain full functionality on those resources of the chip that are not currently undergoing a depowering cycle, hence avoids power cycling those all simultaneously.

8. 发明授权

US11415664B2 Method and system for obtaining an adaptive angle-doppler ambiguity function in MIMO radars 有权
公开(公告)号：US11415664B2
公开(公告)日：2022-08-16
申请号：US16490824
申请日：2018-03-01
申请人： IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. , UNIVERSITE DU LUXEMBOURG
发明人： Christian Hammes , Yogesh Nijsure , Bjorn Ottersten , Thiemo Spielmann , Bhavani Shankar Mysore Rama Rao , Udo Schroder
IPC分类号： G01S13/58 , G01S7/35 , G01S13/00 , G01S13/42 , G01S13/536 , G01S13/931 , H01Q21/29 , G01S13/52
摘要： A method for obtaining an adaptive angle-Doppler ambiguity function (AF) for a target using multiple-input-multiple-output (MIMO) radar that includes a transmit antenna array having a plurality of antenna elements. The method includes generating transmit signals for transmission by the transmit antenna array, the transmit signals defining at least a first transmit trajectory of a phase center within the transmit antenna array; transmitting the transmit signals using the transmit antenna array and receiving receive signals from the target, the receive signals resulting from the incidence of the transmit signals upon the target; and obtaining at least an angle-Doppler ambiguity function (AF) from the receive signals. The first transmit trajectory is such that, in operation, the phase center undergoes random phase center motion (PCM), such that a phase center position within the transmit antenna array varies randomly with time. A system for obtaining an AF is also disclosed.

9. 发明申请

US20220002655A1 MICROFLUIDIC IN VITRO MODEL FOR ELUCIDATING THE MOLECULAR EFFECTS OF SIMULATED DIETARY REGIMENS ON GUT MICROBIOTA AND HOST CELLS 有权
公开(公告)号：US20220002655A1
公开(公告)日：2022-01-06
申请号：US17294587
申请日：2019-11-15
申请人： Universite Du Luxembourg
发明人： Paul Wilmes , Kacy Greenhalgh
IPC分类号： C12M1/34 , C12M3/06 , C12M1/00 , G01N33/50
摘要： A microfluidic cell culture device for performing dietary compounds—host microbiota cells molecular interactions, the microfluidic cells culture device comprising two or more channels, wherein at least two adjacent channels are cell culture channels separated by a permeable or semi permeable membrane adapted to prevent passage of cells thereacross, a first channel of the at least two adjacent channels supporting a culture of microbiota cells of a host and a second of the at least two channels supporting at least one probiotics culture and being perfused with a medium of dietary compound.

10. 发明授权

US10768291B2 Method and system for obtaining angle-doppler signatures in MIMO radars 有权
公开(公告)号：US10768291B2
公开(公告)日：2020-09-08
申请号：US16341269
申请日：2017-10-04
申请人： IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. , UNIVERSITE DU LUXEMBOURG
发明人： Christian Hammes , Yogesh Nijsure , Bjorn Ottersten , Udo Schroder
IPC分类号： G01S13/34 , G01S13/42 , G01S13/87 , G01S13/93 , G01S13/931
摘要： A method for obtaining an angle-Doppler signature for a target using sparse arrays in multiple-input-multiple-output (MIMO) radar, the MIMO radar including a transmit antenna array, the transmit antenna array being at least one-dimensional (e.g. 2-D, 3-D or 4-D) and having a plurality of antenna elements. The method includes generating transmit signals for transmission by the transmit antenna array, the transmit signals defining at least a first transmit trajectory (e.g. circular) of a phase center within the transmit antenna array, and transmitting the transmit signals using Amplitude Modulation on the transmit antenna array. The method further includes receiving receive signals from the target, the receive signals resulting from the incidence of the transmit signals upon the target, and determining the angle-Doppler signature from the receive signals. The first transmit trajectory is such that, in operation, the phase center undergoes non-linear motion within the transmit antenna array.

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