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1. 发明授权

US11099179B2 Device and method for detecting substances present in biological or chemical samples 有权
公开(公告)号：US11099179B2
公开(公告)日：2021-08-24
申请号：US15868571
申请日：2018-01-11
申请人： Torsten Matthias
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G01N33/543 , G01N35/00 , G01N35/02
摘要： The present invention relates to a device and a method for detecting substances which are present in biological or chemical samples, each substance producing an optically detectable signal upon reaction with a reagent. The device further comprises a sample carrier with at least two receptacles for receiving samples and is characterized in that at least part of the receptacle is equipped to receive at least 2 reagents each, and in that a camera for recording an image which shows at least one receptacle filled with at least two reagents for the detection of different substances, and an evaluation device for evaluating the samples which device is designed such as to evaluate each image by analyzing the signals in the image. Said method comprises the following steps: Introducing at least two reagents into one receptacle of a sample carrier, and optionally immobilizing the reagents, adding the sample to the receptacle, recording an image by means of a camera such that the image shows the receptacle which is loaded with at least two reagents, and evaluating the image by analyzing the color spectrum of the samples in the image.

2. 发明授权

US09734421B2 Method and device for inspecting the volume and the composition of at least one sample 有权
公开(公告)号：US09734421B2
公开(公告)日：2017-08-15
申请号：US14354908
申请日：2012-10-29
申请人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G06K9/32 , G06K9/00 , G06F19/00 , G01N1/14 , G01N21/59 , G06T7/00
CPC分类号： G06K9/3216 , G06T7/0012
摘要： The present invention relates to a method and a device for inspecting a volume and/or a composition of at least one, especially fluid, sample. The method comprises the steps of making available at least one pipette, in which an interface is formed between a sample and a fluid which is adjacent to the sample. That interface being optically perceptible outside the pipette as an interface line between the sample and at least one fluid that extends approximately (about) horizontally A camera is arranged in an image so that the marking and at least a first section of the at least one pipette is shown in a recorded imageThe present invention thus provides an apparatus and method for a singular approach to detecting, evaluation and recording results.

3. 发明授权

US11099178B2 Device and method for detecting substances present in biological or chemical samples 有权
公开(公告)号：US11099178B2
公开(公告)日：2021-08-24
申请号：US14354910
申请日：2012-10-29
申请人： Torsten Matthias
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G01N33/543 , G01N35/00 , G01N35/02
摘要： The present invention relates to a device and a method for detecting substances which are present in biological or chemical samples, each substance producing an optically detectable signal upon reaction with a reagent. The device further comprises a sample carrier with at least two receptacles for receiving samples and is characterized in that at least part of the receptacle is equipped to receive at least 2 reagents each, and in that a camera for recording an image which shows at least one receptacle filled with at least two reagents for the detection of different substances, and an evaluation device for evaluating the samples which device is designed such as to evaluate each image by analyzing the signals in the image. Said method comprises the following steps: Introducing at least two reagents into one receptacle of a sample carrier, and optionally immobilizing the reagents, adding the sample to the receptacle, recording an image by means of a camera such that the image shows the receptacle which is loaded with at least two reagents, and evaluating the image by analyzing the color spectrum of the samples in the image.

4. 发明授权

US09734420B2 Device and method for inspecting a volume of a sample 有权
公开(公告)号：US09734420B2
公开(公告)日：2017-08-15
申请号：US14354782
申请日：2012-10-29
申请人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
发明人： Torsten Matthias , Hans-Peter Schimon , Jens Blecken , Markus Wulf
IPC分类号： G06K9/32 , G06K9/00 , G06F19/00 , G01N1/14 , G01N21/59 , G01F23/292 , G01N35/10 , G06T7/00
CPC分类号： G06K9/3216 , G01F23/292 , G01N35/1016 , G01N2035/1025 , G06T7/0012
摘要： The present invention relates to a device useful for inspecting a sample. The device includes a camera in order to arrange that camera in an image field so that an interface line and a marker of the camera can be imaged as a recorded image. The device also has an evaluation unit which allows an evaluation of the recorded image and the marking in order to provide information to the observer.

5. 发明授权

US08142719B2 Analysis device 有权
标题翻译：分析装置
公开(公告)号：US08142719B2
公开(公告)日：2012-03-27
申请号：US12291375
申请日：2008-11-07
申请人： Torsten Matthias , Hugo Ribeiro , Hans-Peter Schimon , Peter Van Praet
发明人： Torsten Matthias , Hugo Ribeiro , Hans-Peter Schimon , Peter Van Praet
IPC分类号： G01N21/00 , B01J19/00
CPC分类号： G01N35/025 , G01N35/028 , G01N35/1083 , G01N2035/0455 , Y10T436/11 , Y10T436/111666 , Y10T436/114998
摘要： A device is disclosed, being an analysis device for the study of biological or chemical samples by means of a reagent liquid supplied via a pipette. The device has an instrument housing with a base plate, a working plate arranged on the base plate horizontally to receive the samples in a sample holder having several wells, a robot manipulator arranged above the working plate, which carries a horizontal support arm with a slide. A needle system is fastened to the slide and can move in the Z direction, carrying 3 needles and being brought into vertical positions by a first vertical drive. The needle tips can be placed in an upper position above and in a lower position below a well. The middle needle can move vertically relative to the other two needles, which can be raised and lowered by a second vertical drive. The horizontal spacing of the three needles is so small that all three needles can be positioned with their tips inside the same wells. In particular, the working plate is mounted on the base plate so that it can turn.
摘要翻译：公开了一种用于通过经由移液管供应的试剂液体来研究生物或化学样品的分析装置。该装置具有带有基板的工具壳体，水平地布置在基板上的工作板，用于接收具有多个井的样本保持器中的样本;布置在工作板上方的机器人操纵器，其携带具有滑块的水平支撑臂。针系统固定在滑块上，可沿Z方向移动，携带3针，并通过第一垂直驱动器进入垂直位置。针头可以放置在井下方的上部位置和下部位置。中针可以相对于另外两个针垂直移动，这两个针可以通过第二个垂直驱动器升高和降低。三针的水平间距非常小，以至于所有三个针都可以放置在同一个孔内。特别地，工作板安装在基板上，使其可以转动。

6. 发明申请

US20090280572A1 Analysis device 有权
标题翻译：分析装置
公开(公告)号：US20090280572A1
公开(公告)日：2009-11-12
申请号：US12291375
申请日：2008-11-07
申请人： Hugo Ribeiro , Hans-Peter Schimon , Peter Van Praet
发明人： Hugo Ribeiro , Hans-Peter Schimon , Peter Van Praet
IPC分类号： G01N21/00 , B01J19/00
CPC分类号： G01N35/025 , G01N35/028 , G01N35/1083 , G01N2035/0455 , Y10T436/11 , Y10T436/111666 , Y10T436/114998
摘要： A device is disclosed, being an analysis device for the study of biological or chemical samples by means of a reagent liquid supplied via a pipette. The device has an instrument housing with a base plate, a working plate arranged on the base plate horizontally to receive the samples in a sample holder having several wells, a robot manipulator arranged above the working plate, which carries a horizontal support arm with a slide. A needle system is fastened to the slide and can move in the Z direction, carrying 3 needles and being brought into vertical positions by a first vertical drive. The needle tips can be placed in an upper position above and in a lower position below a well. The middle needle can move vertically relative to the other two needles, which can be raised and lowered by a second vertical drive. The horizontal spacing of the three needles is so small that all three needles can be positioned with their tips inside the same wells. In particular, the working plate is mounted on the base plate so that it can turn.
摘要翻译：公开了一种用于通过经由移液管供应的试剂液体来研究生物或化学样品的分析装置。该装置具有带有基板的工具壳体，水平地布置在基板上的工作板，用于接收具有多个井的样本保持器中的样本;布置在工作板上方的机器人操纵器，其携带具有滑块的水平支撑臂。针系统固定在滑块上，可沿Z方向移动，携带3针，并通过第一垂直驱动器进入垂直位置。针头可以放置在井下方的上部位置和下部位置。中针可以相对于另外两个针垂直移动，这两个针可以通过第二个垂直驱动器升高和降低。三针的水平间距非常小，以至于所有三个针都可以放置在同一个孔内。特别地，工作板安装在基板上，使其可以转动。

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