专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08182768B2 Interface assembly for pre-concentrating analytes in chromatography 有权
标题翻译：用于在色谱中预浓缩分析物的界面组件
公开(公告)号：US08182768B2
公开(公告)日：2012-05-22
申请号：US11251187
申请日：2005-10-14
申请人： Andrew Tipler , John H. Vanderhoef , James E. Botelho
发明人： Andrew Tipler , John H. Vanderhoef , James E. Botelho
IPC分类号： G01N30/02
CPC分类号： G01N30/16 , G01N35/1095 , G01N2030/085 , Y10T436/25 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A system for interfacing a sampling device and a chromatograph and for pre-concentrating analytes in a sample prior to introducing the sample into the chromatographic column is generally disclosed comprising an interface housing with a first channel and an adsorbent housing with a second channel, which contains at least one adsorbent. Valveless conduits permit fluid to be communicated between the sampling device and the first channel, between the first channel and the second channel, and the first channel and the column. In some embodiments, fluid flows in one direction when the analytes are adsorbed and in the opposite direction when analytes are desorbed. In certain embodiments, two different adsorbents are disposed in the second channel to adsorb different types of analytes.
摘要翻译：通常公开了用于在将样品引入色谱柱之前将取样装置和色谱仪连接并用于预先浓缩样品中的分析物的系统，其包括具有第一通道的界面壳体和具有第二通道的吸附剂壳体，其包含至少一种吸附剂。无阀管道允许流体在采样装置和第一通道之间，第一通道和第二通道之间以及第一通道和塔之间连通。在一些实施方案中，当分析物被吸附时，流体沿一个方向流动，并且当分析物被解吸时在相反方向流动。在某些实施方案中，两个不同的吸附剂设置在第二通道中以吸附不同类型的分析物。

2. 发明申请

US20110300564A1 DIAGNOSIS OF PRE-ECLAMPSIA 有权
标题翻译：前列腺炎的诊断
公开(公告)号：US20110300564A1
公开(公告)日：2011-12-08
申请号：US13213802
申请日：2011-08-19
申请人： Lucilla POSTON , Paul Townsend SEED , Beverley Jane HUNT , Lucy Charlotte Chappell
发明人： Lucilla POSTON , Paul Townsend SEED , Beverley Jane HUNT , Lucy Charlotte Chappell
IPC分类号： G01N33/566 , G06F19/10
CPC分类号： G01N33/74 , G01N2333/8132 , G01N2800/52 , G06F19/00
摘要： The present invention relates to a method of predicting pre-eclampsia (PE). The present invention also relates to a diagnostic kit for performing a method of predicting PE. In particular, the method determining the level of two or more markers selected from placenta growth factor (PlGF), plasminogen activator inhibitor-1 (PAI-1), plasminogen activator inhibitor-2 (PAI-2) and leptin.
摘要翻译：本发明涉及一种预测先兆子痫（PE）的方法。本发明还涉及一种用于执行预测PE的方法的诊断套件。特别地，确定选自胎盘生长因子（PlGF），纤溶酶原激活物抑制剂-1（PAI-1），纤溶酶原激活物抑制剂-2（PAI-2）和瘦蛋白的两种或更多种标志物的水平的方法。

3. 发明授权

US07711523B2 System for remote monitoring and control of an instrument 有权
标题翻译：用于远程监测和控制仪器的系统
公开(公告)号：US07711523B2
公开(公告)日：2010-05-04
申请号：US11932380
申请日：2007-10-31
申请人： Richard Linley , John A. Olbert
发明人： Richard Linley , John A. Olbert
IPC分类号： G06F17/00 , G06F19/00
CPC分类号： G06F17/3089 , G06F19/00 , G06F19/3418
摘要： The invention relates to a web-based instrument and data management system and method including software executing on an instrument controller computer system that receives a web file from a web browsing software executing on a remote computer. The web-based interface also extracts a user identifier and a requested action, determines with the user is authorized for the requested action and performs the action is the user is authorized. If not the web-based interface generates and transmits a web file indicating that the user is not authorized for the requested action.
摘要翻译：本发明涉及一种基于网络的仪器和数据管理系统和方法，包括在仪器控制器计算机系统上执行的软件，所述仪器控制器计算机系统从在远程计算机上执行的web浏览软件接收web文件。基于Web的界面还提取用户标识符和请求的动作，用户确定被授权为被请求的动作，并且执行用户被授权的动作。如果基于Web的接口不是生成并发送指示用户未被授权请求的动作的Web文件。

4. 发明授权

US07709267B2 System and method for extracting headspace vapor 有权
标题翻译：用于提取顶空蒸气的系统和方法
公开(公告)号：US07709267B2
公开(公告)日：2010-05-04
申请号：US11251310
申请日：2005-10-14
申请人： Andrew Tipler , Christopher Mazza
发明人： Andrew Tipler , Christopher Mazza
IPC分类号： G01N30/24 , G01N1/22 , G01N35/10 , G01N30/02 , G01N30/08
CPC分类号： G01N1/2226 , G01N30/06 , G01N2001/2229 , G01N2030/085 , G01N2030/121 , Y10T436/11 , Y10T436/25 , Y10T436/25375 , Y10T436/255 , Y10T436/25875 , G01N30/32 , G01N2030/405
摘要： A system and method for extracting headspace vapor is generally disclosed comprising pressurizing a vessel containing headspace vapor with a carrier gas and subsequently venting the sample mixture through an adsorbent trap and out a vent. A flow controller is employed to gradually increase the flow therethrough as the pressure drops as a result of the gradual depletion of headspace vapor in the vessel and, in certain embodiments, the flow controller maintains a constant flow rate. Due to the time saved, in some embodiments, multiple pressurization-venting cycles are implemented to maximize the amount of vapor extracted from the vial. Due to the constant flow rate, in certain embodiments, the pressure decay is monitored and compared to reference values in order to determine whether the sample vessel has a leak or other defect.
摘要翻译：通常公开了一种用于提取顶空蒸气的系统和方法，包括用载气加压含有顶空蒸气的容器，随后将样品混合物通过吸附剂阱并排出出口。采用流量控制器随着压力下降而逐渐增加流量，这是由于容器中顶部空气蒸气逐渐消耗的结果，并且在某些实施例中，流量控制器保持恒定的流速。由于节省了时间，在一些实施例中，实施多个加压 - 排气循环以最大化从小瓶中提取的蒸气的量。由于恒定的流速，在某些实施例中，监测压力衰减并与参考值进行比较，以确定样品容器是否具有泄漏或其他缺陷。

5. 发明授权

US07638287B2 Detecting and predicting pre-eclampsia 有权
标题翻译：检测和预测先兆子痫
公开(公告)号：US07638287B2
公开(公告)日：2009-12-29
申请号：US11623480
申请日：2007-01-16
申请人： Lucilla Poston , Andrew Shennan
发明人： Lucilla Poston , Andrew Shennan
IPC分类号： G01N33/68 , G01N33/53
CPC分类号： G01N33/689 , G01N33/6863 , G01N33/6893 , G01N2333/475 , G01N2333/715 , G01N2333/96486 , G01N2800/368 , G06F19/00
摘要： The technology described herein relates to methods of detecting or predicting pre-eclampsia (PE). The technology described herein also relates to commercial packages, such as diagnostic kits, for performing a method of detecting or predicting PE. In particular, the technology described herein provides methods of predicting pre-eclampsia when determining the levels of biochemical markers.
摘要翻译：本文描述的技术涉及检测或预测先兆子痫（PE）的方法。本文描述的技术还涉及用于执行检测或预测PE的方法的商业包装，例如诊断套件。特别地，本文所述的技术提供了当确定生物化学标记物水平时预测先兆子痫的方法。

6. 发明申请

US20090253156A1 MASS SPECTROMETRY METHODS FOR MULTIPLEXED QUANTIFICATION OF PROTEIN KINASES AND PHOSPHATASES 审中-公开
标题翻译：蛋白激酶和磷酸酶多重定量的质谱方法
公开(公告)号：US20090253156A1
公开(公告)日：2009-10-08
申请号：US11744705
申请日：2007-05-04
申请人： Wayne F. Patton , Bing Xie
发明人： Wayne F. Patton , Bing Xie
IPC分类号： C12Q1/48 , C12Q1/37
CPC分类号： G01N33/573 , G01N33/6848 , G01N2333/912 , G01N2333/916
摘要： The inventions relates to methods and kits for capture and/or analysis of kinases and/or phosphatases in one or more samples. In some embodiments, a kinase inhibitor, e.g. staurosporine or its derivative, is used to capture kinases from a sample. In some embodiments, a phosphatase inhibitor, e.g. microcystin or its derivative, is used to capture phosphatases from a sample. Methods for quantitative analysis of captured kinases and/or proteases are also provided. In some embodiments, quantitative analysis is accomplished using mass spectrometry. In addition, the invention provides kits related to same.
摘要翻译：本发明涉及用于在一个或多个样品中捕获和/或分析激酶和/或磷酸酶的方法和试剂盒。在一些实施方案中，激酶抑制剂，例如，星形孢菌素或其衍生物，用于从样品中捕获激酶。在一些实施方案中，磷酸酶抑制剂，例如，微囊藻毒素或其衍生物用于从样品中捕获磷酸酶。还提供了捕获的激酶和/或蛋白酶的定量分析方法。在一些实施方案中，使用质谱法进行定量分析。此外，本发明提供了与其相关的试剂盒。

7. 发明授权

US07572319B2 Analyte pre-concentrator for gas chromatography 有权
标题翻译：用于气相色谱的分析物预浓缩器
公开(公告)号：US07572319B2
公开(公告)日：2009-08-11
申请号：US11963938
申请日：2007-12-24
申请人： Andrew Tipler , Gary Campbell , Mark Collins
发明人： Andrew Tipler , Gary Campbell , Mark Collins
IPC分类号： B01D53/22
CPC分类号： B01D53/025 , B01D2253/102 , G01N30/12 , G01N2001/2229 , G01N2030/085 , G01N2030/121 , G01N2030/127 , G01N2030/128
摘要： An analyte pre-concentrator for gas chromatography is disclosed generally comprising a tube packed with an adsorbent, wherein the tube may serve as the liner of a chromatographic injector, as an adsorbent trap coupled to a chromatographic column, and/or as an adsorbent trap coupled to a headspace sampler. Preferably, a heating device allows the tube to be heated. In a preferred embodiment, the analyte pre-concentrator further comprises a column isolating accessory so that a chromatographic column can be temporarily isolated from substances flowing through the tube.
摘要翻译：公开了用于气相色谱的分析物预浓缩器，其通常包括填充有吸附剂的管，其中该管可用作色谱注射器的衬垫，作为与色谱柱耦合的吸附阱，和/或作为吸附阱捕获到顶空进样器。优选地，加热装置允许管被加热。在优选实施方案中，分析物预浓缩器还包括柱分离附件，使得色谱柱可以暂时与流过管的物质隔离。

8. 发明申请

US20090133511A1 FLUID HANDLING DEVICE WITH ULTRASOUND SENSOR AND METHODS AND SYSTEMS USING SAME 有权
标题翻译：具有超声波传感器的流体处理装置和使用该传感器的方法和系统
公开(公告)号：US20090133511A1
公开(公告)日：2009-05-28
申请号：US11945193
申请日：2007-11-26
申请人： Karl R. Heinze , Lee Brady , William J. Austhof
发明人： Karl R. Heinze , Lee Brady , William J. Austhof
IPC分类号： G01N1/10 , F04B41/02 , F04B41/06
CPC分类号： G01F23/2962 , G01N35/1011 , G01N2035/1025 , Y10T137/85978 , Y10T137/86131
摘要： A device comprising a sampling probe configured to sample a fluid, and an ultrasound sensor coupled to the sampling probe and configured to transmit and receive ultrasound energy, the ultrasound sensor further configured to generate a first signal by receiving ultrasound energy reflected from a fluid surface of the fluid is provided. Fluid handling systems and methods of using the fluid handling devices and systems are also disclosed.
摘要翻译：一种包括被配置为对流体进行采样的采样探针的装置以及耦合到所述采样探针并被配置为发射和接收超声能量的超声波传感器，所述超声传感器进一步经配置以通过接收从流体表面反射的超声波产生第一信号提供流体。还公开了流体处理系统和使用流体处理装置和系统的方法。

9. 发明授权

US07536926B2 Dispensing apparatus having means for loading pipette tips in a dispense head 有权
标题翻译：分配装置具有用于将移液管尖端装载到分配头中的装置
公开(公告)号：US07536926B2
公开(公告)日：2009-05-26
申请号：US11267011
申请日：2005-11-04
申请人： Richard A. Carl
发明人： Richard A. Carl
IPC分类号： G01N1/00
CPC分类号： B01L9/543 , B01L3/0279 , B01L2300/0829 , G01N35/1074 , G01N2035/103
摘要： A self contained dispensing head apparatus wherein a modified pipette tip box tray carrier is utilized to furnish pipette tips, carried in a standard pipette tip box, by a pipette tip box tray carrier to the head apparatus and wherein means are provided to engage the pipette tip box tray carrier in a manner whereby the pipette tips are loaded into corresponding internal cylinders formed in the dispense block head. The dispense block head comprises a solid block of material having a plurality of internal cylinders to engage the pipette tips in a sealing arrangement. The pipette tips are modified from the conventional design in that a disk-shaped ring portion is interposed adjacent one end of the pipette tip, a tapered end of the tip allowing a seal to be formed with the dispense block head internal cylinders.
摘要翻译：一种自包装的分配头设备，其中利用改进的移液管吸头盒托盘托架，通过移液管吸头托盘托架向头部设备提供携带在标准移液管吸头盒中的移液管吸头，并且其中提供了用于接合移液管吸头盒托盘托架，其中移液器吸头被装载到形成在分配块头部中的相应的内部气缸中。分配块头包括具有多个内部圆柱体的固体块材料，以密封装置接合移液管尖端。移液器吸头从现有技术的设计改进而成，其中盘形环部分邻近移液管尖端的一端插入，尖端的锥形端允许用分配块头内部圆筒形成密封。

10. 发明授权

US07459313B2 Method for measuring effective temperature inside a sealed container 有权
标题翻译：用于测量密封容器内的有效温度的方法
公开(公告)号：US07459313B2
公开(公告)日：2008-12-02
申请号：US10621942
申请日：2003-07-17
申请人： Andrew Tipler
发明人： Andrew Tipler
IPC分类号： G01N7/00
CPC分类号： G01K11/00 , G01K11/02 , Y10T436/25875
摘要： A method of measuring the effective temperature inside a sealed container having a headspace is provided. A liquid solvent is added to the container, and a solid compound is added to the liquid solvent to create a saturated solution. Vapor of the saturated solution is allowed to equilibrate in the headspace of the sealed container, and a volume thereof is transferred to a chromatographic column, where chromatographic readings of the equilibrated vapor are taken. A temperature within the sealed container is then calculated based upon the chromatographic readings of the equilibrated vapor, wherein the temperature calculation is based upon the concentrations of the liquid solvent and the solid compound in the equilibrated vapor.
摘要翻译：提供一种测量具有顶部空间的密封容器内的有效温度的方法。将液体溶剂加入到容器中，并将固体化合物加入到液体溶剂中以产生饱和溶液。允许饱和溶液的蒸气在密封容器的顶部空间中平衡，并将其体积转移到色谱柱，其中取平衡蒸气的色谱读数。然后基于平衡蒸气的色谱读数计算密封容器内的温度，其中温度计算基于平衡蒸气中的液体溶剂和固体化合物的浓度。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式