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1. 发明授权

US11292626B2 Binding device 有权
公开(公告)号：US11292626B2
公开(公告)日：2022-04-05
申请号：US16971880
申请日：2019-02-04
申请人： NICHIBAN CO., LTD. , MICROJENICS INC.
发明人： Masanori Sato , Toru Katada , Masahiko Noda
IPC分类号： B65B13/02 , B65B13/04 , B65B13/18 , A01G17/08 , B65B27/10
摘要： A binding device that prevents damage to binding tape including a biodegradable material as a base material comprises a pressing surface formed on a resin attachment which is detachably mounted on a head of a tape holding plate, and therefore it is possible to mount an attachment of a shape and material suitable for binding tape to be used. Furthermore, because the tape receiving plate is formed by a rubber plate, the tape receiving plate is able to absorb a shock generated by the pointed end of the tape holding plate entering the tape receiving plate. With this arrangement, it possible to prevent damage to fragile binding tape including a biodegradable material as a base material.

2. 发明申请

US20190167568A1 Transdermal Drug Delivery System and Method for Using Same 审中-公开
公开(公告)号：US20190167568A1
公开(公告)日：2019-06-06
申请号：US16313739
申请日：2017-06-29
申请人： SENJU USA, INC. , NICHIBAN CO., LTD.
发明人： Takahiro OGAWA , Akiharu ISOWAKI , Tetsuo KIDA , Koji KAWAHARA , Emiko TESHIMA , Teppei OSAKO
IPC分类号： A61K9/00 , A61K9/70 , A61K31/573
摘要： [PROBLEMS TO BE SOLVED]To provide a method of advantageously improving a transdermal permeation amount of a steroid drug to diseased portions when treating ophthalmic diseases such as chalazion, blepharitis, allergic conjunctivitis, vernal keratoconjunctivitis, and meibomian gland dysfunction.[SOLUTION]To provide the transdermal drug delivery system for administering a drug via the eyelid skins that have been treated with a microneedle array, featured in that the drug is a water-soluble steroid, and the transdermal drug delivery system is a water-containing base adhesive skin patch.

3. 发明申请

US20100217171A1 Patch Material 审中-公开
标题翻译：补丁材料
公开(公告)号：US20100217171A1
公开(公告)日：2010-08-26
申请号：US12675952
申请日：2008-06-03
申请人： Kenji Fukano , Hiromichi Fujisawa , Shuichi Watanabe
发明人： Kenji Fukano , Hiromichi Fujisawa , Shuichi Watanabe
IPC分类号： A61F13/02
CPC分类号： A61Q19/08 , A61F13/0243 , A61F13/0253 , A61F13/0256 , A61K8/0208
摘要： A patch having a layer structure that a pressure sensitive adhesive layer is provided on one surface of a base layer, wherein the base layer is an elastomer film having a thickness of 1 to 10 μm, the thickness of the pressure sensitive adhesive layer is 1 to 15 μm, the total thickness of the base layer and the pressure sensitive adhesive layer is within a range of from 2 to 20 μm, the 10% tensile load of the patch in each of machine and transverse directions is 0.01 to 1.2 N/10 mm, assuming that the 10% tensile load value of the patch in the machine direction is X (N/10 mm), the thickness value of the patch is Y (μm), and the thickness value of the base layer is Z (μm), the patch satisfies the relationship of XY=0.02 to 15, or XZ=0.01 to 7, and the pressure sensitive adhesive layer exhibits adhesive strength of 0.1 N/10 mm or more.
摘要翻译：具有压敏粘合剂层的层结构的贴片在基层的一个表面上设置，其中基层为厚度为1〜10μm的弹性体膜，压敏粘合剂层的厚度为1〜 15μm时，基层和压敏粘合剂层的总厚度在2〜20μm的范围内，贴片的纵向和横向各自的10％拉伸载荷为0.01〜1.2N / 10mm 假设贴片在机器方向的10％拉伸载荷值为X（N / 10mm）时，贴片的厚度值为Y（μm），基底层的厚度值为Z（μm），补片满足XY = 0.02〜15或XZ = 0.01〜7的关系，粘合剂层的粘合强度为0.1N / 10mm以上。

4. 发明申请

US20090155343A1 Tamsulosin-Containing Transdermal Patch 审中-公开
标题翻译：含有坦索罗辛的透皮贴剂
公开(公告)号：US20090155343A1
公开(公告)日：2009-06-18
申请号：US12226146
申请日：2007-04-03
申请人： Kouji Kawahara , Kenichi Nakao , Haruna Yamaki
发明人： Kouji Kawahara , Kenichi Nakao , Haruna Yamaki
IPC分类号： A61K9/70 , A61K31/18
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61K31/18
摘要： A tamsulosin-containing transdermal patch. A transdermal patch comprising a backing-layer and an adhesive layer on the backing-layer, characterized in that the adhesive layer contains an acrylic adhesive, further contains tamsulosin as an active ingredient in an amount of 0.1 to 20% by mass of the total mass of the adhesive layer and, if desired, a polyoxyethylene alkyl ether which is an additive playing a role in increasing solubility and a propylene glycol fatty acid ester which is an additive playing a role in promoting percutaneous absorption is provided. Further, a transdermal patch comprising a backing-layer and an adhesive layer on the backing-layer, characterized in that the adhesive layer contains a synthetic rubber adhesive, further contains tamsulosin as an active ingredient in an amount of 0.1 to 20% by mass of the total mass of the adhesive layer and a propylene glycol fatty acid ester which is an additive playing a role in promoting percutaneous absorption is provided.
摘要翻译：含有坦索罗辛的透皮贴剂。一种透皮贴剂，其包含背衬层和背衬层上的粘合剂层，其特征在于，所述粘合剂层含有丙烯酸粘合剂，还含有作为活性成分的坦索罗辛，其量为总质量的0.1〜20质量％的粘合剂层，并且如果需要，提供作为增加溶解性的添加剂的聚氧乙烯烷基醚和作为促进经皮吸收的作用的添加剂的丙二醇脂肪酸酯。此外，在背衬层上包含背衬层和粘合剂层的透皮贴剂，其特征在于，所述粘合剂层含有合成橡胶粘合剂，还含有作为活性成分的坦索罗辛，其量为0.1〜20质量％提供粘合剂层的总质量和作为促进经皮吸收作用的添加剂的丙二醇脂肪酸酯。

5. 发明授权

US4505891A Medicinal adhesive sheets for heart diseases and a process for the preparation thereof 失效
标题翻译：用于心脏病的药用粘合片及其制备方法
公开(公告)号：US4505891A
公开(公告)日：1985-03-19
申请号：US387885
申请日：1982-06-09
申请人： Toshio Ito
发明人： Toshio Ito
IPC分类号： A61K31/21 , A61K9/32 , A61K9/70 , A61L15/58 , A61M37/00 , A61P9/08 , A61P9/10 , A61F13/00 , A61L15/03
CPC分类号： A61K9/7061 , A61L15/58
摘要： A medicinal adhesive sheet for heart diseases having only slight irritation to the skin, which comprises an adhesive composition supported on a suitable base, the composition containing as essential ingredients a copolymer containing dodecyl methacrylate as main monomer component and a suitable amount of nitroglycerin, and the composition having an excellent nitroglycerin-releasing property and a good balance between adhesive strength and cohesive strength.
摘要翻译： PCT No.PCT / JP81 / 00291 Sec。 371日期1982年6月9日 102（e）日期1982年6月9日PCT提交1981年10月19日PCT公布。出版物WO82 / 01317 日本1982年4月29日。一种对皮肤轻微刺激的心脏病的药用粘合片，其包含负载在合适的基底上的粘合剂组合物，该组合物含有作为主要成分的含有作为主要单体成分的甲基丙烯酸十二烷基酯的共聚物和适量的硝酸甘油，并且具有优异的硝酸甘油释放性能和粘合强度与内聚强度之间良好平衡的组合物。

6. 发明授权

US4421737A Pressure-sensitive adhesive tape or pressure-sensitive adhesive sheet containing nitroglycerin 失效
标题翻译：含有硝酸甘油的压敏粘合带或压敏粘合片
公开(公告)号：US4421737A
公开(公告)日：1983-12-20
申请号：US247307
申请日：1981-03-25
申请人： Toshio Ito , Hiroshi Ninomiya , Kunio Yamagami
发明人： Toshio Ito , Hiroshi Ninomiya , Kunio Yamagami
IPC分类号： C09J7/02 , A61K9/70 , A61K31/21 , A61F13/02
CPC分类号： A61K9/7053 , A61K31/21 , A61K9/7076 , Y10T428/2839 , Y10T428/2896
摘要： Pressure-sensitive adhesive tapes or sheets containing nitroglycerin whose release and retention are regulated. Process for the production of pressure-sensitive adhesive tapes or sheets containing nitroglycerin, in which a rubber base adhesives applied on a backing is coated with softeners containing nitroglycerin and then covered with an impermeable protection sheet. Process for the production of pressure-sensitive adhesive tapes or sheets containing nitroglycerin, in which a backing is coated with adhesives comprising a rubber base adhesive basis and tackifiers, while a separator is coated with a solution of softeners for rubber base adhesives in which nitroglycerin is dissolved, and then the softener coated surface of the separator is laid on the adhesive-coated surface of the backing and they are kept at the temperature at which nitroglycerin is stable so that the nitroglycerin and softeners transfer into the adhesives.
摘要翻译：含有释放和保留的硝酸甘油压敏粘合带或片。用于生产含有硝酸甘油的压敏粘合带或片材的方法，其中施加在背衬上的橡胶基底粘合剂涂覆有含有硝酸甘油的软化剂，然后用不透水保护片材覆盖。用于生产含有硝酸甘油的压敏粘合带或片材的方法，其中背衬涂覆有包含橡胶基粘合剂基础的粘合剂和增粘剂，同时隔板涂覆有用于橡胶基粘合剂的软化剂溶液，其中硝酸甘油是溶解，然后将分离器的软化剂涂覆的表面铺设在背衬的粘合剂涂覆的表面上，并将其保持在硝酸甘油稳定的温度，以使硝酸甘油和软化剂转移到粘合剂中。

7. 发明申请

US20210086929A1 BINDING DEVICE 有权
公开(公告)号：US20210086929A1
公开(公告)日：2021-03-25
申请号：US16971880
申请日：2019-02-04
申请人： NICHIBAN CO., LTD. , MICROJENICS INC.
发明人： Masanori SATO , Toru KATADA , Masahiko NODA
IPC分类号： B65B13/02 , B65B13/18 , B65B13/04
摘要： Provided is a binding device that prevents damage to binding tape including a biodegradable material as a base material.
A pressing surface 106 is formed on an attachment 105 including resin, which is detachably mounted on a head 84 of a tape holding plate 83, and therefore it is possible to mount an attachment 105 of a shape and material suitable for binding tape 7 to be used. Furthermore, because the tape receiving plate 87 is formed by a rubber plate, the tape receiving plate 87 is able to absorb a shock generated by the pointed end 85 of the tape holding plate 83 entering the tape receiving plate 87. With this arrangement, it possible to prevent damage to fragile binding tape 7 including a biodegradable material as a base material.

8. 发明授权

US10822526B2 Adhesive resin pellets and method of manufacturing same 有权
公开(公告)号：US10822526B2
公开(公告)日：2020-11-03
申请号：US15561148
申请日：2015-12-18
申请人： NICHIBAN CO., LTD.
发明人： Syuji Ichimura , Mikihiro Endou , Yusuke Sugiyama
IPC分类号： B29B9/10 , B29C48/00 , B29B9/16 , C09J201/00 , B29B9/06 , C09J7/30 , C08J3/12 , C09J7/00 , B29B9/12 , B29B13/06 , C09J9/00 , C08K7/00 , B29C48/05 , B29C48/04 , C09J7/10
摘要： A method for manufacturing adhesive resin pellets includes adding an antiblocking agent to water, melting an adhesive resin and extruding the adhesive resin into the water, and cutting the adhesive resin extruded into the water to form adhesive resin pellets. Polyolefin fine particles used for the antiblocking agent have an average particle diameter of 1 μm or more and less than 18 μm, and the adhesive resin has an adhesive force of less than 15.00 N/25 mm.

9. 发明申请

US20200317964A1 SEPARATOR, AND ADHESIVE TAPE OR SHEET WITH SEPARATOR 审中-公开
公开(公告)号：US20200317964A1
公开(公告)日：2020-10-08
申请号：US16955474
申请日：2018-12-27
申请人： NICHIBAN CO., LTD.
发明人： Tomoyuki INAGAKI , Yukinori KOGA
IPC分类号： C09J7/40 , B32B3/30 , B32B7/06 , B32B27/32
摘要： The present invention provides an adhesive tape or sheet with a separator comprising an adhesive tape or sheet comprising a support layer and an adhesive layer laminated on the upper side of the support layer; and a separator located on the upper side of the adhesive layer, wherein the separator has a three-layer structure in which a first A layer, a B layer, and a second A layer are laminated in this order from the lower side; the first A layer and the second A layer are formed of the same type of unstretched polyolefin film, and the B layer is formed of a biaxially stretched polyolefin film; and the thickness of the first A layer is 70% or more and 130% or less of the thickness of the second A layer.

10. 发明授权

US09586388B2 Chip-resistant film 有权
标题翻译：耐芯片
公开(公告)号：US09586388B2
公开(公告)日：2017-03-07
申请号：US14564799
申请日：2014-12-09
申请人： NICHIBAN CO., LTD.
发明人： Syuji Ichimura , Masataka Sudo , Tomohisa Kato
IPC分类号： B32B37/12 , C09J5/00 , B32B27/32 , C09J7/02 , C09J133/02
CPC分类号： B32B37/12 , B32B27/32 , C09J5/00 , C09J7/29 , C09J133/02 , C09J2201/162 , C09J2423/006 , C09J2433/00 , Y10T156/10 , Y10T428/2848
摘要： A chip-resistant film includes a composite substrate having an ionomer layer and a polyolefin-based polymer layer, with a strength at upper yield point of 10 to 40 N/10 mm, wherein a pressure-sensitive adhesive, which may be an acrylic pressure-sensitive adhesive, is placed over the polyolefin-based polymer layer. The chip-resistant film may also include an intermediate adhesive layer positioned between the ionomer layer and the polyolefin-based polymer layer. The chip resistance of an object to which the chip-resistant film has been applied is improved.
摘要翻译：耐芯片膜包括具有离聚物层和聚烯烃类聚合物层的复合基材，其强度在10〜40N / 10mm的上屈服点，其中压敏粘合剂可以是丙烯酸压力敏感粘合剂，放置在聚烯烃基聚合物层上。耐芯片膜还可以包括位于离聚物层和聚烯烃基聚合物层之间的中间粘合剂层。提高了抗切屑膜的物体的耐芯片电阻。

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