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1. 发明授权

US07120276B1 Method and apparatus for image processing 有权
标题翻译：图像处理方法和装置
公开(公告)号：US07120276B1
公开(公告)日：2006-10-10
申请号：US09936998
申请日：2000-03-17
申请人： John Michael Brady , Paul Michael Hayton , Stephen Mark Smith
发明人： John Michael Brady , Paul Michael Hayton , Stephen Mark Smith
IPC分类号： G06K9/00
CPC分类号： G06K9/6206 , G06T7/277
摘要： An example system and method for processing image data of a plurality of time-separated images of a non-rigid body to detect movement of the body involves calculating and storing, for each of a plurality of sampling points in each image, a plurality of candidate movements together with the estimated probability of each candidate. For each sampling point, the probability of each of the candidate movements is recalculated based on the stored probability of that candidate movement and the probabilities of the candidate movements at neighboring sampling points. A motion field indicative of the non-rigid body movement is generated from the recalculated probabilities.
摘要翻译：用于处理非刚性体的多个时间分离图像的图像数据以检测身体移动的示例性系统和方法包括为每个图像中的多个采样点中的每一个计算和存储多个候选者运动以及每个候选人的估计概率。对于每个采样点，基于所存储的该候选移动的概率和相邻采样点处的候选移动的概率来重新计算每个候选移动的概率。从重新计算的概率产生指示非刚性身体运动的运动场。

2. 发明申请

US20050065734A1 Characterisation of progressive system dysfunction 有权
标题翻译：进行性系统功能障碍的表征
公开(公告)号：US20050065734A1
公开(公告)日：2005-03-24
申请号：US10921473
申请日：2004-08-19
申请人： Jerome Declerck , Thomas Wright , Robert McLaughlin
发明人： Jerome Declerck , Thomas Wright , Robert McLaughlin
IPC分类号： G06T7/00 , G06F19/00 , G01N33/48 , G01N33/50 , G01R31/00
CPC分类号： G06T7/0012
摘要： A technique for assessing the progression of multilateral dysfunction, e.g. bilateral diseases is described. The process consists of two stages: firstly, a ‘health measure’ is computed for each of the features of the multi-lateral dysfunction. One example is in terms of the progression of Parkinson's disease by applying it to the uptake of imaging agent in the two striata of the brain, which can be viewed using SPECT imaging. In this example, a characteristic graph for each striatum is matched to a family of such graphs in order to quantify the state of each striatum as a health measure. Then the lower health measure is plotted against the higher health measure. This point is then projected onto a previously computed disease progression trajectory which is used to assign a percentage to the progression of the disease, from 0% normal to 100% extreme progression of the disease. In addition to the disease progression percentage, the technique also provides a confidence measure of the accuracy of this estimation. The invention is applicable to other forms of multilateral dysfunction, including other human or animal conditions and dysfunction in non-biological systems such as mechanical, electrical or electronic systems.
摘要翻译：评估多发功能障碍进展的技术，例如描述双边疾病。该过程包括两个阶段：首先，为多侧功能障碍的每个特征计算“健康度量”。就帕金森氏病的进展而言，一个例子是通过将其应用于大脑两条纹状体中的成像剂的摄取，可以使用SPECT成像进行观察。在该示例中，每个纹状体的特征图与这样的图的族相匹配，以便将每个纹状体的状态量化为健康度量。然后，较低的健康指标与较高的健康度量相比较。然后将该点投影到先前计算的疾病进展轨迹上，该轨迹用于将疾病进展的百分比从疾病的0％正常到100％极端进展分配。除了疾病进展百分比，该技术还提供了该估计精度的置信度量度。本发明适用于其他形式的多边功能障碍，包括其他人或动物病症和非生物系统如机械，电气或电子系统中的功能障碍。

3. 发明授权

US07394924B2 Scatter correction in scanning imaging systems 失效
标题翻译：扫描成像系统中的散射校正
公开(公告)号：US07394924B2
公开(公告)日：2008-07-01
申请号：US10686382
申请日：2003-10-14
申请人： Bruno Ancelin , Ralph Philip Highnam
发明人： Bruno Ancelin , Ralph Philip Highnam
IPC分类号： G06K9/00 , G01N23/201
CPC分类号： A61B6/5282 , A61B6/06 , A61B6/502 , A61B6/508 , G06T5/003 , G06T5/20 , G06T2207/10116 , G06T2207/30068
摘要： A method of processing a radiographic image obtained with a slot-scanning radiographic system to compensate for scattering of the illuminating beam in the tissue being imaged. A conventional circularly symmetric scatter mask, for example a point spread function, is adjusted to take account of the shape of the detector and time delay integration used in the slot scanning system, the presence of an air gap between the detector and the bottom of the tissue being imaged, and the collimation of the radiation beam. The result is a sharpened and shortened point spread function.
摘要翻译：一种处理通过时隙扫描放射线照相系统获得的放射照相图像以补偿被成像的组织中的照射光束的散射的方法。调整传统的圆对称散射掩模，例如点扩散函数，以考虑到检测器的形状和在时隙扫描系统中使用的时间延迟积分，检测器与底部之间存在气隙成像的组织和辐射束的准直。结果是削尖和缩短点扩散功能。

4. 发明授权

US07020313B2 Registration of multi-modality data in imaging 失效
标题翻译：成像中多模态数据的注册
公开(公告)号：US07020313B2
公开(公告)日：2006-03-28
申请号：US10618565
申请日：2003-07-11
申请人： Jérôme Marie Joseph Declerck , Christian Peter Behrenbruch
发明人： Jérôme Marie Joseph Declerck , Christian Peter Behrenbruch
IPC分类号： G06K9/00
CPC分类号： G06T7/30 , G06T2207/30004
摘要： A method of registration of a functional emission image to another image, e.g. a structural/anatomical image, is disclosed in which the emission image is first processed to mask out regions of the background and lungs identified in a corresponding transmission image. Only areas which are not masked out in the emission image are matched to areas in the x-ray image. The x-ray image and masked emission image may then be displayed in superposition.
摘要翻译：将功能发射图像配准到另一图像的方法，例如。公开了结构/解剖图像，其中首先处理发射图像以掩蔽相应透射图像中识别的背景区域和肺。只有在发射图像中未被掩蔽的区域与x射线图像中的区域相匹配。然后可以叠加地显示x射线图像和掩蔽的发射图像。

5. 发明申请

US20050152617A1 Similarity measures 失效
标题翻译：相似度量
公开(公告)号：US20050152617A1
公开(公告)日：2005-07-14
申请号：US10935045
申请日：2004-09-07
申请人： Alexis Roche , Michael Brady , Jerome DeClerck , Olivier Corolleur
发明人： Alexis Roche , Michael Brady , Jerome DeClerck , Olivier Corolleur
IPC分类号： A61B5/00 , A61B5/055 , A61B6/03 , G06T7/00 , G06K9/62
CPC分类号： G06T7/30 , G06T2207/30016
摘要： A method of matching data sets, such as different images, by estimating a transformation which relates the two images. Different candidate transformations are scored by using a similarity measure calculated on the basis of probability density functions derived from the two data sets themselves. The probability density functions are based on local likelihood density estimation (LLDE). The technique is applicable to image registration, and also to data fusion.
摘要翻译：通过估计涉及两个图像的变换来匹配诸如不同图像的数据集的方法。通过使用基于从两个数据集本身导出的概率密度函数计算的相似性度量来对不同候选变换进行评分。概率密度函数基于局部似然密度估计（LLDE）。该技术适用于图像配准，也适用于数据融合。

6. 发明申请

US20040167395A1 Dynamic medical imaging 审中-公开
标题翻译：动态医学成像
公开(公告)号：US20040167395A1
公开(公告)日：2004-08-26
申请号：US10756953
申请日：2004-01-13
申请人： MIRADA SOLUTIONS LIMITED, British body corporate
发明人： Christian Peter Behrenbruch , Jerome Marie Joseph Declerck , John Michael Brady
IPC分类号： A61B005/05 , A61B006/00
CPC分类号： G06T7/20 , G06T7/0016 , G06T7/30 , G06T2207/30004
摘要： A method of dynamic medical imaging in which the quality of image registration or motion correction between the frames is assessed by examining the temporal behaviour of a region of interest through the sequence, and in particular how closely the behaviour follows expected behaviour. For a temporal sequence a temporal model of the expected behaviour of the region of interest is available and the quality of fit between the model and the data points from the dynamic imaging sequence can be calculated. In image regions of high patient motion the fit will be poor, whereas if there is no patient motion the fit will be better. The quality of fit can be displayed on the image as an indication of the validity of motion correction, and in areas of poor fit the motion correction can be re-executed using different parameters to try and improve the fit between the behaviour model and the actual data points. The invention is applicable to any contrast-enhanced medical imaging technique.
摘要翻译：一种动态医学成像方法，其中通过检查所述序列中的感兴趣区域的时间特征来评估帧之间的图像配准或运动校正的质量，特别是该行为遵循预期行为的密切程度。对于时间序列，感兴趣区域的期望行为的时间模型是可用的，并且可以计算来自动态成像序列的模型和数据点之间的拟合质量。在患者运动较高的图像区域中，适合度较差，而如果没有患者运动，则适合度将更好。可以在图像上显示合适的质量，作为运动校正的有效性的指示，并且在较差拟合的区域中，可以使用不同的参数重新执行运动校正，以尝试改善行为模型与实际之间的拟合数据点。本发明适用于任何对比度增强的医学成像技术。

7. 发明申请

US20040143449A1 Processing systems 审中-公开
标题翻译：处理系统
公开(公告)号：US20040143449A1
公开(公告)日：2004-07-22
申请号：US10734655
申请日：2003-12-11
申请人： Mirada Solutions Limited
发明人： Christian Peter Behrenbruch , John Michael Brady , Jerome Marie Joseph Declerck
IPC分类号： G06F017/60
CPC分类号： G06F19/3468 , A61B5/055 , G01R33/281 , G06F19/321 , G06T7/0012
摘要： A processing system which comprises a processing apparatus and a processing agent which is administered to a processing subject. The processing agent has a primary behaviour which provides the desired process result in conjunction with the apparatus, but also has a distinctive signature characteristic which is detected by test functionality in the processing system. The behaviour of the processing system can be modified in response to the test result. In an example such as a contrast enhanced medical imaging, the full functionality of the imaging equipment may be available only if a contrast agent having the particular distinctive signature characteristic is used, thus tying use of the apparatus to use of a particular agent.
摘要翻译：一种处理系统，包括对处理对象施加的处理装置和处理剂。处理代理具有与设备一起提供期望的处理结果的主要行为，而且具有由处理系统中的测试功能检测到的特征性特征。可以根据测试结果修改处理系统的行为。在诸如对比度增强的医学成像的例子中，成像设备的全部功能仅在使用具有特定特征性特征的造影剂时可用，因此使用该装置来使用特定的药剂。

8. 发明授权

US07315640B1 X-ray image processing 失效
标题翻译： X射线图像处理
公开(公告)号：US07315640B1
公开(公告)日：2008-01-01
申请号：US09914460
申请日：2000-02-21
申请人： John Michael Brady , Ralph Highnam
发明人： John Michael Brady , Ralph Highnam
IPC分类号： G06K9/00
CPC分类号： G06T5/002 , G06T5/003 , G06T2207/10116 , G06T2207/30068
摘要： A method of enhancing and normalizing x-ray images, particularly mammograms, by correcting the image for digitizer blur, glare from the intensifying screen and the anode-heel effect. The method also allows the calculation of the compressed thickness of the imaged breast and calculation of the contribution to the mammograms of the extra focal radiation. The correction of the image for glare from the intensifying screen allows the detection of noise, such as film shot noise, in the image, and in particular the differentiation between such noise and microcalcifications.
摘要翻译：通过校正数字化仪模糊的图像，来自增强屏幕的眩光和阳极 - 脚跟效应来增强和归一化X射线图像，特别是乳房X线照片的方法。该方法还允许计算成像乳房的压缩厚度并计算对额外焦点辐射的乳房X线照片的贡献。来自增强屏幕的用于眩光的图像的校正允许检测图像中的噪声，例如胶片拍摄噪声，并且特别地，这种噪声和微钙化之间的差异。

9. 发明授权

US07260254B2 Comparing images 有权
标题翻译：比较图像
公开(公告)号：US07260254B2
公开(公告)日：2007-08-21
申请号：US10303225
申请日：2002-11-25
申请人： Ralph Philip Highnam , Peter Eric Taylor , Bruno Ancelin , John Michael Brady
发明人： Ralph Philip Highnam , Peter Eric Taylor , Bruno Ancelin , John Michael Brady
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T2207/30068
摘要： Comparing first and second images taken on different imaging systems and under different exposure conditions is achieved by the steps of: applying a model to the data representing the first image, which model simulates at least one process step in the creation of said first image, to derive a representation of the first image at a level of processing common to the creation of the second image; and applying a further model to said representation, which model simulates at least one process step in the creation of said second image, to derive a further representation of the first image which corresponds to the same level of processing as said second image.
摘要翻译：比较在不同成像系统和不同曝光条件下拍摄的第一和第二图像是通过以下步骤实现的：将模型应用于表示第一图像的数据，该模型模拟创建所述第一图像中的至少一个处理步骤，在第二图像的创建共同的处理级别上导出第一图像的表示; 以及将另外的模型应用于所述表示，所述模型模拟所述第二图像的创建中的至少一个处理步骤，以导出对应于与所述第二图像相同的处理级别的第一图像的另外的表示。

10. 发明授权

US07200612B2 processing data for interpretation 有权
标题翻译：处理数据进行解释
公开(公告)号：US07200612B2
公开(公告)日：2007-04-03
申请号：US10221992
申请日：2001-03-23
申请人： John Michael Brady , Jacques Feldmar
发明人： John Michael Brady , Jacques Feldmar
IPC分类号： G06F7/00 , G06F17/30 , G06F17/00 , G06Q10/00 , G06Q50/00 , A61B5/00 , G06F19/00 , G06K9/00
CPC分类号： G06Q50/24 , G06F19/00 , G06F19/324 , G06F19/3418 , G06N5/04 , G06Q50/22 , G16H50/50 , Y10S707/99945 , Y10S707/99948
摘要： A system for improving sensor-based decision making provides for the automatic submission of data obtained locally from instrumentation (such as image data) together with the interpretation of that data, which can be the output of some software which has been checked and possibly corrected by a user according to his/her expertise, to a remote database via an internetwork. The submission to the remote database is preferably automatic so that the remote database grows over time. The local site can access the remote database to retrieve information to assist in interpretation of the locally produced data (for example similar images and their corresponding interpretations), or can retrieve updated or improved software or parameters improving the software used for processing the data. The information on the remote database can also be reprocessed by software agents to provide statistical information based on information from a variety of such local sites. The system is particularly useful in improving the interpretation of data which is difficult to interpret such as medical image data (e.g. mammographic or cardiac ultrasound data).
摘要翻译：用于改进基于传感器的决策的系统提供了从仪器（例如图像数据）本地获取的数据的自动提交以及该数据的解释，其可以是已经被检查并且可能由根据他/她的专业知识的用户，通过互联网络到远程数据库。远程数据库的提交最好是自动的，以便远程数据库随着时间的推移而增长。本地站点可以访问远程数据库以检索信息，以帮助解释本地生成的数据（例如类似图像及其对应的解释），或者可以检索更新或改进的软件或参数，以改进用于处理数据的软件。远程数据库上的信息也可以由软件代理重新处理，以根据来自各种这样的本地站点的信息提供统计信息。该系统特别可用于改进难以解释的数据的解释，例如医学图像数据（例如乳房X线照相术或心脏超声数据）。

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