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1. 发明授权

US5164186A Drug-releaser 失效
标题翻译：药物释放者
公开(公告)号：US5164186A
公开(公告)日：1992-11-17
申请号：US617376
申请日：1990-11-21
申请人： Sumiaki Tsuru , Ichiro Masuno
发明人： Sumiaki Tsuru , Ichiro Masuno
IPC分类号： A61K9/00 , A61K9/20
CPC分类号： A61K9/0024 , A61K9/2009 , A61K9/2027 , A61K9/205
摘要： Disclosed is a drug-releaser comprising a porous body of biocompatibility filled with a medicine. Specifically, such porous body is made of baked calcium phosphate, 2-hydroxyethylmethacrylate, chitin, chitosan or their delivatives. Implantation or artery-injection of such drug-releaser causes a discernible curing effect on affected parts of the living body without causing any irritativeness. The steady release of the medicine from HAP particles to affected parts and the blockade of surrounding capillary vessels leading to such affected parts causes a remarkable tumor inhibitory effect.
摘要翻译：公开了一种药物释放剂，其包含填充有药物的生物相容性的多孔体。具体地说，这种多孔体由焙烧的磷酸钙，甲基丙烯酸2-羟基乙酯，壳多糖，壳聚糖或其衍生物制成。这种药物释放剂的植入或动脉注射对生物体的受影响部位产生明显的固化作用，而不引起任何刺激性。药物从HAP颗粒稳定释放到受影响的部位，以及阻断周围的毛细血管，导致这些受影响的部位导致显着的肿瘤抑制作用。

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