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1. 发明授权

US11004692B2 Method for ultra-shallow etching using neutral beam processing based on gas cluster ion beam technology 有权
公开(公告)号：US11004692B2
公开(公告)日：2021-05-11
申请号：US15758436
申请日：2016-07-22
申请人： Exogenesis Corporation
发明人： Sean R. Kirkpatrick , Richard C. Svrluga
IPC分类号： H01L21/311 , H01L21/3213 , C03C15/02 , H01L21/02 , H01L21/306 , H01L21/3065 , H01L21/3105 , C03C15/00 , H01L21/265 , H01L21/308
摘要： A method for shallow etching a substrate surface forms a shallow modified substrate layer overlying unmodified substrate using an accelerated neutral beam and etches the modified layer, stopping at the unmodified substrate beneath, producing controlled shallow etched substrate surfaces.

2. 发明申请

US20200083048A1 Method and Apparatus to Eliminate Contaminant Particles from an Accelerated Neutral Atom Beam and Thereby Protect a Beam Target 审中-公开
公开(公告)号：US20200083048A1
公开(公告)日：2020-03-12
申请号：US16566649
申请日：2019-09-10
申请人： Exogenesis Corporation
发明人： Allen R. Kirkpatrick
IPC分类号： H01L21/263 , H01J37/147 , H01J37/305
摘要： An improved ANAB system or process substantially or fully eliminating contaminant particles from reaching a beam target by adding to the usual primary (first) ionizer of the ANAB system or process an additional (second) ionizer to ionize contaminant particles and means to block or retard the ionized particles to prevent their reaching the beam target.

3. 发明申请

US20160140143A1 SYSTEM AND METHOD FOR A GEOSPATIAL DATABASE 审中-公开
标题翻译：地质数据库的系统和方法
公开(公告)号：US20160140143A1
公开(公告)日：2016-05-19
申请号：US14942285
申请日：2015-11-16
申请人： Exogenesis Corporation
发明人： Sean Michael Anklam , John Beakes Tuthill, III , Barnabas Sprague
IPC分类号： G06F17/30
CPC分类号： G06F16/29
摘要： The present disclosure describes methods, systems, and program products for generating an enhanced database, such as a geospatial database, and for searching an enhanced database, such as a geospatial database. The disclosed methods, systems, and program products incorporate a process for assigning labels to objects, such as polygons, linestrings, and points, based on the relationship between such polygons, linestrings, and points.
摘要翻译：本公开描述了用于生成诸如地理空间数据库的增强数据库以及用于搜索诸如地理空间数据库的增强数据库的方法，系统和程序产品。所公开的方法，系统和程序产品包括基于这样的多边形，线条和点之间的关系来为诸如多边形，线形和点之类的对象分配标签的过程。

4. 发明授权

US09315798B2 Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby 有权
标题翻译：改善表面和物体表面生物活性特征的方法得以改善
公开(公告)号：US09315798B2
公开(公告)日：2016-04-19
申请号：US14238774
申请日：2012-08-22
申请人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga
发明人： Joseph Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga
IPC分类号： A61F2/02 , H01J37/317 , H01J37/05 , A61L27/14 , C12N13/00 , A61L27/06 , A61L27/16 , A61L27/38 , A61L27/50
CPC分类号： A61L27/38 , A61L27/06 , A61L27/16 , A61L27/18 , A61L27/50 , A61L2300/64 , A61L2400/18 , C12N13/00 , C08L27/18
摘要： A method for improving bioactivity of a surface of an implantable object comprising titania, titanium, an alloy of titanium, and/or polytetrafluoroethylene (PTFE) and implantable objects prepared thereby provides forming an accelerated neutral beam derived from an accelerated gas-cluster ion-beam (GCIB) in a reduced-pressure chamber, introducing an implantable object into the reduced-pressure chamber, and irradiating at least a first portion of the surface of said implantable object with a GCIB-derived neutral beam.
摘要翻译：包括二氧化钛，钛，钛合金和/或聚四氟乙烯（PTFE）的可植入物体的表面的生物活性的改善方法和由此制备的可植入物体形成加速的中性束，其由加速的气体 - 团簇离子束（GCIB）在减压室中，将可植入物体引入减压室中，以及用GCIB衍生的中性光束照射所述可植入物体的表面的至少第一部分。

5. 发明授权

US08847148B2 Method and apparatus for neutral beam processing based on gas cluster ion beam technology 有权
公开(公告)号：US08847148B2
公开(公告)日：2014-09-30
申请号：US13215514
申请日：2011-08-23
申请人： Sean R. Kirkpatrick , Allen R. Kirkpatrick
发明人： Sean R. Kirkpatrick , Allen R. Kirkpatrick
IPC分类号： H01J37/00 , H01J37/147 , H01J37/317 , H01J37/05
CPC分类号： G03F1/80 , B24B37/04 , G03F1/82 , H01J37/05 , H01J37/147 , H01J37/317 , H01J37/3171 , H01J2237/0041 , H01J2237/0812 , H01J2237/15 , H01L21/02115 , H01L21/02274 , H01L21/26506 , H01L21/26513 , H01L21/26566 , H01L21/31105 , H01L21/31111 , H01L29/36 , H05H3/02 , Y10T428/24355 , Y10T428/24479 , Y10T428/30
摘要： An apparatus, method and products thereof provide an accelerated neutral beam derived from an accelerated gas cluster ion beam for processing materials.

6. 发明申请

US20130138213A1 MEDICAL DEVICE FOR BONE IMPLANT AND METHOD FOR PRODUCING SUCH A DEVICE 审中-公开
标题翻译：用于骨植入的医疗装置和用于生产这种装置的方法
公开(公告)号：US20130138213A1
公开(公告)日：2013-05-30
申请号：US13746795
申请日：2013-01-22
申请人： EXOGENESIS CORPORATION
发明人： Richard C. Svrluga , Laurence B. Tarrant , Stephen M. Blinn
IPC分类号： C23C14/22 , A61F2/28
CPC分类号： A61F2/28 , A61C8/0012 , A61C8/0018 , A61F2/30771 , A61F2002/30677 , A61F2002/3068 , A61F2002/30795 , A61F2250/0068 , A61F2310/00796 , A61L27/10 , A61L27/50 , A61L27/54 , A61L2300/406 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/602 , A61L2300/606 , A61L2400/18 , B05D3/068 , C23C14/221 , C23C14/48
摘要： A method of modifying a surface of implantable medical device provides coating at least a first portion of the surface of the medical device with a therapeutic agent to form a coated surface region; and irradiating at least a portion of the coated surface region with a gas cluster ion beam infusing the therapeutic agent into the at least a portion of the coated surface region.
摘要翻译：修改可植入医疗装置的表面的方法提供用医疗装置的表面的至少第一部分涂覆治疗剂以形成涂覆的表面区域; 以及将所述涂覆的表面区域的至少一部分用喷射所述治疗剂的气体团簇离子束照射到所述涂覆的表面区域的至少一部分中。

7. 发明申请

US20130105710A1 DIAGNOSTIC METHOD AND APPARATUS FOR CHARACTERIZATION OF A NEUTRAL BEAM AND FOR PROCESS CONTROL THEREWITH 有权
标题翻译：诊断方法和装置，用于表征中性束及其过程控制
公开(公告)号：US20130105710A1
公开(公告)日：2013-05-02
申请号：US13660295
申请日：2012-10-25
申请人： Sean R. Kirkpatrick , Allen R. Kirkpatrick
发明人： Sean R. Kirkpatrick , Allen R. Kirkpatrick
IPC分类号： G01T7/00
CPC分类号： H01J37/244 , H01J37/304 , H01J37/317 , H01J2237/0812 , H01J2237/24514 , H01L21/26566
摘要： An apparatus and method for characterizing a particle beam provides receiving a particle beam in a central region of a reduced pressure enclosure; impacting the received beam against a beam strike that is thermally isolated from the enclosure; measuring a temperature change of the beam strike due to the impacting beam; measuring a pressure change in the enclosure due to receiving the beam; and processing the measured temperature change and the measured pressure change to determine beam characteristics.
摘要翻译：用于表征粒子束的装置和方法提供了在减压外壳的中心区域中接收粒子束; 撞击接收的梁抵抗与外壳热隔离的梁撞击; 测量由于冲击梁造成的射束的温度变化; 测量由于接收光束而导致的外壳中的压力变化; 并处理测量的温度变化和测量的压力变化以确定光束特性。

8. 发明授权

US08217372B2 Gas-cluster-jet generator and gas-cluster ion-beam apparatus utilizing an improved gas-cluster-jet generator 有权
标题翻译：采用改进型气体簇射流发生器的气体簇射流发生器和气体簇离子束装置
公开(公告)号：US08217372B2
公开(公告)日：2012-07-10
申请号：US12825504
申请日：2010-06-29
申请人： Stanley Harrison
发明人： Stanley Harrison
IPC分类号： H01J37/08 , H01J37/317 , G21K5/10
CPC分类号： H01J37/08 , H01J37/301 , H01J2237/045 , H01J2237/0812 , H01J2237/083 , H01J2237/31
摘要： A gas-cluster-jet generator with improved vacuum management techniques and apparatus is disclosed. The gas-cluster-jet generator comprises a substantially conically shaped vacuum chamber for housing the nozzle and jet exit portions of the gas-cluster-jet generator. A skimmer may be located at the narrow end of the conical chamber and a close-coupled vacuum pump is located at the wide end of the conical chamber. Support members for the nozzle are high conductivity “spider” supports that provide support rigidity while minimizing gas flow obstruction for high pumping speed. The conically shaped vacuum chamber redirects un-clustered gas in a direction opposite the direction of the gas-cluster-jet for efficient evacuation of the un-clustered gas. The nozzle and a skimmer may have fixed precision relative alignment, or may optionally have a nozzle aiming adjustment feature for aligning the gas-cluster-jet with the skimmer and downstream beamline components. Also disclosed are various configurations of gas-cluster ion-beam processing tools employing the improved gas-cluster-jet generator.
摘要翻译：公开了一种具有改进的真空管理技术和设备的气体簇射流发生器。气体簇喷射发生器包括用于容纳喷气发生器的喷嘴和喷射出口部分的大致锥形的真空室。撇渣器可以位于锥形室的窄端，并且紧密联接的真空泵位于锥形室的宽端。喷嘴的支撑构件是高导电性“蜘蛛”支撑，其提供支撑刚度，同时最大限度地减少气流阻塞以实现高泵送速度。圆锥形真空室沿着与气体簇射流方向相反的方向重新定向未聚集的气体，以有效排出未聚集的气体。喷嘴和撇渣器可以具有固定的精确度相对对准，或者可以可选地具有用于使气体簇射流与分离器和下游束线部件对准的喷嘴瞄准调整特征。还公开了采用改进的气体 - 簇射流发生器的气体 - 团簇离子束加工工具的各种构造。

9. 发明申请

US20060204534A1 Drug delivery system and method of manufacturing thereof 有权
标题翻译：药物输送系统及其制造方法
公开(公告)号：US20060204534A1
公开(公告)日：2006-09-14
申请号：US11349483
申请日：2006-02-07
申请人： Stephen Blinn , Barry Zide
发明人： Stephen Blinn , Barry Zide
IPC分类号： A61L33/00 , A61F13/02
CPC分类号： C23C14/022 , A61F2/82 , A61F2/86 , A61F2250/0067 , A61L31/14 , A61L31/16 , A61L2300/00 , B05D1/02 , B05D3/0493 , B05D3/06 , C23C14/221 , C23C14/24 , C23C14/505 , C23C14/5833
摘要： Medical devices implanted or otherwise used in a mammal are made less prone to trigger adverse reactions by use of gas cluster ion-beam (GCIB) surface modification adhere various drug molecules directly into or onto the surface of medical devices, and optionally building adhered drug layers upon the first adhered layer to obtain a desired drug elution profile. This is accomplished without the need for a polymer or any other binding agent to retain the drug.
摘要翻译：通过使用气体簇离子束（GCIB）表面改性将植入或以其他方式用于哺乳动物的医疗装置不易于引发不良反应，将各种药物分子直接粘附到医疗装置的表面或其表面上，以及任选地建立附着的药物层在第一粘附层上获得所需的药物洗脱曲线。这是在不需要聚合物或任何其它结合剂来保留药物的情况下完成的。

10. 发明授权

US11698582B2 Method for modifying the wettability and/or other biocompatibility characteristics of a surface of a biological material by the application of gas cluster ion beam technology and biological materials made thereby 有权
公开(公告)号：US11698582B2
公开(公告)日：2023-07-11
申请号：US16239272
申请日：2019-01-03
申请人： Exogenesis Corporation
发明人： Joseph B. Khoury , Laurence B. Tarrant , Sean R. Kirkpatrick , Richard C. Svrluga
IPC分类号： H01J37/05 , H01J37/317 , H01L21/265 , H01L21/311 , H01L21/02 , H05H3/02 , G03F1/80 , G03F1/82 , H01J37/147 , H01L29/36 , B24B37/04
CPC分类号： G03F1/80 , G03F1/82 , H01J37/05 , H01J37/147 , H01J37/317 , H01J37/3171 , H01L21/02115 , H01L21/02274 , H01L21/26506 , H01L21/26513 , H01L21/26566 , H01L21/31105 , H01L21/31111 , H05H3/02 , B24B37/04 , H01J2237/0041 , H01J2237/0812 , H01J2237/15 , H01L29/36 , Y10T428/24355 , Y10T428/24479 , Y10T428/30
摘要： A method for preparing a biological material for implanting provides irradiating at least a portion of the surface of the material with an accelerated Neutral Beam.

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