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1. 发明申请

US20090208951A1 DETECTION OF T-DNA 审中-公开
标题翻译：检测T-DNA
公开(公告)号：US20090208951A1
公开(公告)日：2009-08-20
申请号：US12259810
申请日：2008-10-28
申请人： Perikles Simon
发明人： Perikles Simon
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6888 , C12Q2600/16
摘要： The present invention relates to a method for the detection of transgenic DNA (tDNA) in a living being and to a kit for performing such a method.
摘要翻译：本发明涉及用于检测活体中的转基因DNA（tDNA）的方法和用于进行这种方法的试剂盒。

2. 发明授权

US06913894B2 Antibodies directed against signal regulator proteins 失效
标题翻译：针对信号调节蛋白的抗体
公开(公告)号：US06913894B2
公开(公告)日：2005-07-05
申请号：US10158415
申请日：2002-05-29
申请人： Hans-Jörg Bühring , Axel Ullrich , Zhengjun Chen , Charles Cant
发明人： Hans-Jörg Bühring , Axel Ullrich , Zhengjun Chen , Charles Cant
IPC分类号： C07K16/18 , C12N5/08 , C07K16/28 , C12P21/08 , G01N33/543 , G01N33/567 , G01N33/577
CPC分类号： C07K16/18 , A61K2039/505
摘要： Monoclonal antibodies which bind specifically to the extracellular domain of the SIRP cell surface glycoproteins, and which, in some cases, block the interaction of SIRP with the surface molecule CD47, are described.
摘要翻译：描述了特异性结合SIRP细胞表面糖蛋白的细胞外结构域，并且在某些情况下阻止SIRP与表面分子CD47的相互作用的单克隆抗体。

3. 发明申请

US20100294141A1 METHOD AND DEVICE FOR THE TREATMENT OF MILK, ESPECIALLY BREAST MILK 审中-公开
标题翻译：用于治疗奶酪，特别是乳制品的方法和装置
公开(公告)号：US20100294141A1
公开(公告)日：2010-11-25
申请号：US12833875
申请日：2010-07-09
申请人： Gerhard Jahn , Christian P. Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
发明人： Gerhard Jahn , Christian P. Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
IPC分类号： A23C3/02 , A23C3/04
CPC分类号： A23C3/03 , A23C9/206
摘要： A device for treating milk contained in a container is disclosed. The device comprises at least one heat source that comprises an air bath, a device for setting the container in motion and exposing the container to the heat source for a defined period of time, and a cooling source for cooling the milk.
摘要翻译：公开了一种用于处理容纳在容器中的牛奶的装置。该装置包括至少一个包括空气浴的热源，用于设置容器运动并将容器暴露于热源一定时间的装置，以及用于冷却牛奶的冷却源。

4. 发明授权

US06847847B2 Retina implant assembly and methods for manufacturing the same 有权
标题翻译：视网膜植入组件及其制造方法
公开(公告)号：US06847847B2
公开(公告)日：2005-01-25
申请号：US10011641
申请日：2001-11-07
申请人： Wilfried Nisch , Alfred Stett , Markus Schubert , Michael Graf , Heinz Gerhard Graf , Hugo Hämmerle , Eberhart Zrenner , Martin Stelzle , Helmut Sachs
发明人： Wilfried Nisch , Alfred Stett , Markus Schubert , Michael Graf , Heinz Gerhard Graf , Hugo Hämmerle , Eberhart Zrenner , Martin Stelzle , Helmut Sachs
IPC分类号： A61F2/14 , A61F9/08 , A61N1/36
CPC分类号： A61N1/0543 , A61F2/14 , A61F9/08 , A61N1/3787
摘要： A retina implant including a chip adapted to be implanted into the interior of eye in subretinal contact with the retina. The chip has a plurality of pixel elements on a side thereof facing the lens for receiving an image projected into the retina and a plurality of electrodes for stimulating retina cells. The implants further includes a receiver coil for inductively coupling thereinto electromagnetic energy. The receiver coil coupled to a means for converting an alternating voltage induced into the receiver coil in a direct voltage suited for supplying the chip. The receiver coil is configured as a component separate from the chip, and for being positioned on the eye ball outside the sclera. The chip is connected to the receiver coil via a connecting lead which, in the implanted condition interconnects the interior and the exterior of the eye ball.
摘要翻译：一种视网膜植入物，包括适于植入眼睛内部的芯片，视网膜视网膜与视网膜接触。该芯片在面向透镜的一侧具有多个像素元件，用于接收投影到视网膜中的图像，以及多个用于刺激视网膜细胞的电极。植入物还包括用于感应地耦合到其中的电磁能的接收器线圈。接收器线圈耦合到用于将感应到接收器线圈的交流电压以适于供应芯片的直流电压的装置。接收器线圈被配置为与芯片分离的部件，并且用于定位在巩膜外的眼球上。芯片通过连接引线连接到接收器线圈，该连接引线在植入条件下将眼球的内部和外部互连。

5. 发明授权

US08290568B2 Method for determining a property map of an object, particularly of a living being, based on at least a first image, particularly a magnetic resonance image 有权
标题翻译：基于至少第一图像，特别是磁共振图像来确定对象，特别是生物的属性图的方法
公开(公告)号：US08290568B2
公开(公告)日：2012-10-16
申请号：US12351429
申请日：2009-01-09
申请人： Bernd Pichler , Matthias Hofmann , Bernhard Schölkopf , Florian Steinke
发明人： Bernd Pichler , Matthias Hofmann , Bernhard Schölkopf , Florian Steinke
IPC分类号： A61B5/05
CPC分类号： G01R33/481 , A61B6/037 , G06T7/33 , G06T2207/10088 , G06T2207/30004 , G06T2207/30196
摘要： It is disclosed a system and method (12) for determining a property map (82) of an object, particularly a human being, based on at least a first image (84), particularly an magnetic resonance (MR) image, of the object. In the method (12), a structure of reference pairs is defined in a first step (96), wherein each reference pair (16-26) comprises at least two entries (62). The first entry represents a property value, particularly an attenuation value. The second entry (62) preferably represents a group of image points (67) belonging together, which is extracted particularly from MR images (28) and comprises an interesting image point corresponding to the property value. In another step (98) of the method (12) a plurality of training pairs (16-26) is provided. A structure of the training pairs (16-26) corresponds to the structure of reference pairs, and the entries of respective training pairs (16-26) are known. In another step (100) of the method (12), an assignment between the first entries and the other entries (62-66) of the training pairs (16-26) is determined by machine learning, thus allowing prediction of a property value (88) corresponding to an arbitrary point (90) of the first image (84).
摘要翻译：公开了一种用于基于至少第一图像（84），特别是磁共振（MR）图像来确定对象，特别是人类的属性图（82）的系统和方法（12）。在方法（12）中，在第一步骤（96）中定义参考对的结构，其中每个参考对（16-26）包括至少两个条目（62）。第一项表示属性值，特别是衰减值。第二条目（62）优选地表示属于一组的一组图像点（67），其特别是从MR图像（28）提取并包括与该属性值对应的有趣图像点。在方法（12）的另一步骤（98）中，提供了多个训练对（16-26）。训练对（16-26）的结构对应于参考对的结构，并且各训练对（16-26）的条目是已知的。在方法（12）的另一步骤（100）中，训练对（16-26）的第一条目和其他条目（62-66）之间的分配由机器学习确定，从而允许预测属性值（88）对应于第一图像（84）的任意点（90）。

6. 发明申请

US20120252062A1 Method for diagnosing and/or predicting the development of neurodegenerative diseases 审中-公开
标题翻译：诊断和/或预测神经变性疾病发展的方法
公开(公告)号：US20120252062A1
公开(公告)日：2012-10-04
申请号：US13416203
申请日：2012-03-09
申请人： Saskia Biskup , Natalja Funk
发明人： Saskia Biskup , Natalja Funk
IPC分类号： C12Q1/06
CPC分类号： G01N33/5091 , G01N33/5094 , G01N2800/28
摘要： The present invention relates to a method for diagnosing and/or predicting the development of neurodegenerative diseases; in the method, white blood cells are isolated and enriched or cultivated for forming colony-forming units, wherein CFU-M and other CFU are formed. Subsequently, the relative number of CFU-M formed in the previous cultivation(/enrichment step relative to the other CFUs formed are determined.
摘要翻译：本发明涉及诊断和/或预测神经变性疾病发展的方法。在该方法中，白细胞被分离并富集或培养以形成集落形成单位，其中形成CFU-M和其它CFU。随后，确定在先前培养（/富集步骤相对于其它形成的CFU）中形成的CFU-M的相对数量。

7. 发明授权

US07638489B2 Modulation of angiogenesis by Bartonella henselae 有权
标题翻译：调节巴氏杆菌血管生成
公开(公告)号：US07638489B2
公开(公告)日：2009-12-29
申请号：US11429657
申请日：2006-05-04
申请人： Volkhard Kempf , Tanja Riess , Ingo Autenrieth , Kari Alitalo , Siv Anderson
发明人： Volkhard Kempf , Tanja Riess , Ingo Autenrieth , Kari Alitalo , Siv Anderson
IPC分类号： A01N37/18 , A61K39/00 , A61K39/38 , A61K39/02 , A61K38/00 , A61K38/16
CPC分类号： A61K35/74 , A61K38/164 , A61K39/02 , A61K2039/552 , C07K14/195 , G01N33/56911 , G01N2469/20
摘要： The present invention relates to Bartonella henselae as a component of a pharmaceutical composition for the modulation of the angiogenesis; a nucleic acid molecule that is derived from the gene encoding the Bartonella henselae adhesin A protein (BadA), a vector comprising said nucleic acid molecule; a host containing said nucleic acid molecule or said vector; a (poly)peptide encoded by said nucleic acid molecule; a composition comprising Bartonella henselae bacteria; a composition comprising aforesaid (poly)peptide; a method for treating a human or animal being in need of the modulation of the angiogenesis, a method for detecting an infection by Bartonella in a human or animal being, as well as a method for immunizing a cat.
摘要翻译：本发明涉及作为调节血管发生的药物组合物的组分的巴氏杆菌（Bartonella henselae）衍生自编码巴曲利杆菌粘附素A蛋白（BadA）的基因的核酸分子，包含所述核酸分子的载体; 含有所述核酸分子或所述载体的宿主; 由所述核酸分子编码的（多）肽; 一种组合物，包括黑麦草细菌; 包含上述（多）肽的组合物; 用于治疗需要调节血管发生的人或动物的方法，用于检测人或动物中巴尔多奈氏杆菌感染的方法以及用于免疫猫的方法。

8. 发明授权

US06902899B2 Detection of human papillomaviruses 失效
标题翻译：检测人乳头状瘤病毒
公开(公告)号：US06902899B2
公开(公告)日：2005-06-07
申请号：US10227638
申请日：2002-08-22
申请人： Thomas Iftner
发明人： Thomas Iftner
IPC分类号： G01N33/53 , C12N15/09 , C12N15/37 , C12Q1/68 , C12Q1/70 , G01N33/566 , G01N33/569 , C12P19/34
CPC分类号： C12Q1/708 , C12Q1/6818 , C12Q1/6851 , C12Q1/686
摘要： A method for detecting human papillomaviruses (HPV) in biological material is described, in which method nucleic acids are extracted/isolated from biological material and HPV-specific DNA is detected in the isolated nucleic acids. This method uses at least one of the nucleotide sequences SEQ ID No. 1 or SEQ ID No. 2 from the enclosed sequence listing or sequences which bind to sequences to which one of the sequences SEQ ID No. 1 or SEQ ID No. 2 binds or sequences which are complementary to the abovementioned sequences.
摘要翻译：描述了用于检测生物材料中人乳头状瘤病毒（HPV）的方法，其中方法从生物材料提取/分离核酸，并在分离的核酸中检测HPV特异性DNA。该方法使用来自封闭序列表的核苷酸序列SEQ ID No.1或SEQ ID No.2中的至少一个或与序列SEQ ID No.1或SEQ ID No.2之一结合的序列的序列或与上述序列互补的序列。

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