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1. 发明授权

US10031054B2 Solid-phase microextraction 有权
公开(公告)号：US10031054B2
公开(公告)日：2018-07-24
申请号：US13953389
申请日：2013-07-29
申请人： CTC Analytics AG
发明人： Kai Heinrich Schueler , Melchior Zumbach
IPC分类号： B01L9/06 , G01N1/40 , G01N1/22
摘要： In a method for performing a solid-phase micro-extraction, a holding device connected to an extraction device and secured on an adapter is held, while an actuating device connected to a guide device is moved. A device for performing a solid-phase microextraction comprises an actuating device connected to a guide device, and a holding device connected to an extraction device, wherein the extraction device is guided at least partially in the guide device, and wherein the extraction device is movable relative to the guide device by means of an actuation of the actuating device.

2. 发明授权

US10031051B2 Sample deposition device 有权
公开(公告)号：US10031051B2
公开(公告)日：2018-07-24
申请号：US15168943
申请日：2016-05-31
申请人： CTC Analytics AG
发明人： Werner Doebelin , Thomas Maetzke , Chris C. E. Van Tilburg
IPC分类号： G01N1/14 , G01N35/10 , B08B3/08 , B08B9/023 , B08B9/032 , G01N1/10 , G01N30/02
摘要： A device for collecting a sample and for depositing the sample in a sample-receiving port of a measuring apparatus comprises a first connection element (8) with three connections for fluid, and a second connection element (7), and a hollow needle (5) for collecting and depositing the sample. A first feed line (9) for a first washing liquid is connected via a first pump to a first connection for fluid of the first connection element (8). A second feed line (10) for a second washing liquid is connected via a second pump to a second connection for fluid of the first connection element (8). A connection for fluid of the second connection element (7) is connected to the third connection for fluid of the first connection element (8), and the second connection element (7) is connected to a dosing device (1) and to the hollow needle (5). A valve (2) is arranged between the third connection for fluid of the first connection element (8) and the second connection element (7).

3. 发明申请

US20170285055A1 METHOD FOR OPERATING A DOSING DEVICE 审中-公开
公开(公告)号：US20170285055A1
公开(公告)日：2017-10-05
申请号：US15472777
申请日：2017-03-29
申请人： CTC Analytics AG
发明人： Lucas LUETHY , Beat LUETHY
IPC分类号： G01N35/10
CPC分类号： G01N35/1016 , G01F23/2921 , G01N35/1004 , G01N35/1011 , G01N2035/1006 , G01N2035/1025
摘要： The present application relates to a method for operating a dosing device with a control unit and a dosing unit. The dosing unit has a cannula with a first volume and a tip, and also a sampling container fluidically connected to the cannula. In a first step, the dosing unit is moved linearly at a predetermined speed in a first direction along an axis, such that the cannula is moved into a vessel containing at least one liquid. At the same time, fluid is aspirated constantly through the cannula with a predetermined volumetric flow by a pump device. At least one optical parameter of the aspirated fluid is measured by at least one optical sensor, which is arranged between the cannula and the sampling container. When a change of the at least one optical parameter is detected, a first position of the dosing unit on the axis is stored by the control unit and the movement of the dosing unit is interrupted. The control unit then calculates a second position of the dosing unit on the axis, at which second position the tip of the cannula has penetrated a first phase boundary, in particular upon immersion into the liquid. The calculation is performed on the basis of the first position, the predetermined speed, the first volume and the predetermined volumetric flow.

4. 发明申请

US20160320354A1 DEVICE FOR EXTRACTING A VOLATILE COMPONENT 审中-公开
标题翻译：提取挥发成分的装置
公开(公告)号：US20160320354A1
公开(公告)日：2016-11-03
申请号：US15141984
申请日：2016-04-29
申请人： CTC Analytics AG
发明人： Stefan Anton CRETNIK , Kai Heinrich SCHUELER , Melchior ZUMBACH
IPC分类号： G01N30/04
CPC分类号： G01N1/2226 , G01N30/16 , G01N30/18 , G01N2001/2229 , G01N2030/121 , G01N2030/128
摘要： The present application relates to a device for extracting volatile components from a sample. The device comprises a sample vessel for receiving the sample with a supply line and with a discharge line, wherein the sample vessel is closed in a gas-tight manner, and also a gas reservoir, which is connected to the supply line. Moreover, the device has a trap element, which is fluidically connected to the discharge line and which has at least one absorber material. The trap element is connected releasably to the discharge line, wherein the trap element has a gas outlet such that, when the trap element is connected to the discharge line, a gas from the gas reservoir can flow through said trap element.
摘要翻译：本申请涉及一种用于从样品中提取挥发性成分的装置。该装置包括用于用供应管线和排放管线接收样品的样品容器，其中样品容器以气密方式封闭，以及连接到供应管线的气体储存器。此外，该装置具有捕集元件，其流体连接到排出管线并且具有至少一个吸收材料。捕集元件可释放地连接到排放管线，其中捕集元件具有气体出口，使得当捕集元件连接到排出管线时，来自气体储存器的气体可以流过所述捕集元件。

5. 发明申请

US20160320271A1 DEVICE FOR EXTRACTING VOLATILE COMPONENTS 审中-公开
标题翻译：提取挥发性成分的装置
公开(公告)号：US20160320271A1
公开(公告)日：2016-11-03
申请号：US15135001
申请日：2016-04-21
申请人： CTC Analytics AG
发明人： Kai Heinrich SCHUELER , Melchior ZUMBACH , Stefan Anton CRETNIK
IPC分类号： G01N1/24 , G01N1/22
CPC分类号： G01N1/24 , G01N1/2214 , G01N1/2226 , G01N1/405 , G01N30/12 , G01N2001/2229 , G01N2001/2282 , G01N2001/247 , G01N2030/121
摘要： The present application relates to a device for extracting volatile components from a sample received in a sample vessel, wherein the sample vessel is closed in a gas-tight manner. The device moreover has a discharge line and a supply line, which protrude into the sample vessel. The supply line comprises a first valve with which a flow of gas through the supply line can be throttled and/or interrupted. A suction opening of a pump is fluidically connected to the discharge line via a first fluid line, such that the pressure conditions in the device can be controlled by the capacity of the pump and by the setting of the first valve. A second fluid line fluidically connects the supply line to an output opening of the pump, such that sample vessel, supply line, discharge line and pump form a closed gas circuit. A trap element with at least one sorption material is fluidically connected to the first fluid line or the second fluid line.
摘要翻译：本申请涉及一种用于从容纳在样品容器中的样品中提取挥发性组分的装置，其中样品容器以气密方式封闭。此外，该装置具有突出到样品容器中的排出管线和供给管线。供应管线包括第一阀，通过供应管线的气体流可以通过该第一阀节流和/或中断。泵的吸入口经由第一流体管线流体地连接到排放管线，使得可以通过泵的容量和第一阀的设定来控制装置中的压力条件。第二流体管线将供应管路流体地连接到泵的输出开口，使得样品容器，供应管线，排出管线和泵形成封闭的气体回路。具有至少一种吸附材料的捕集元件与第一流体管线或第二流体管线流体连接。

6. 发明申请

US20160274003A1 SAMPLE DEPOSITION DEVICE 审中-公开
标题翻译：样品沉积装置
公开(公告)号：US20160274003A1
公开(公告)日：2016-09-22
申请号：US15168943
申请日：2016-05-31
申请人： CTC Analytics AG
发明人： Werner DOEBELIN , Thomas MAETZKE , Chris C. E. VAN TILBURG
IPC分类号： G01N1/14 , B08B9/023 , B08B9/032 , B08B3/08
CPC分类号： G01N1/14 , B08B3/08 , B08B9/023 , B08B9/0325 , G01N1/10 , G01N30/02 , G01N35/1004 , G01N35/1097 , G01N2030/027
摘要： A device for collecting a sample and for depositing the sample in a sample-receiving port of a measuring apparatus comprises a first connection element (8) with three connections for fluid, and a second connection element (7), and a hollow needle (5) for collecting and depositing the sample. A first feed line (9) for a first washing liquid is connected via a first pump to a first connection for fluid of the first connection element (8). A second feed line (10) for a second washing liquid is connected via a second pump to a second connection for fluid of the first connection element (8). A connection for fluid of the second connection element (7) is connected to the third connection for fluid of the first connection element (8), and the second connection element (7) is connected to a dosing device (1) and to the hollow needle (5). A valve (2) is arranged between the third connection for fluid of the first connection element (8) and the second connection element (7).
摘要翻译：用于收集样品并将样品沉积在测量装置的样品接收端口中的装置包括具有用于流体的三个连接的第一连接元件（8）和第二连接元件（7）和中空针（5））用于收集和沉积样品。用于第一洗涤液体的第一供给管线（9）经由第一泵连接到用于第一连接元件（8）的流体的第一连接件。用于第二洗涤液体的第二进料管线（10）经由第二泵连接到用于第一连接元件（8）的流体的第二连接件。用于第二连接元件（7）的流体的连接件连接到用于第一连接元件（8）的流体的第三连接件，并且第二连接元件（7）连接到计量装置（1）和中空针（5）。在用于第一连接元件（8）和第二连接元件（7）的流体的第三连接件之间布置有阀（2）。

7. 发明申请

US20090206970A1 DEVICE FOR COUPLING AN ATTACHMENT 审中-公开
标题翻译：用于耦合附件的装置
公开(公告)号：US20090206970A1
公开(公告)日：2009-08-20
申请号：US11718744
申请日：2005-11-07
申请人： Hansjörg Cueni , Heiner Scherrer
发明人： Hansjörg Cueni , Heiner Scherrer
IPC分类号： H01F7/02
CPC分类号： G01N35/04 , G01N35/0099 , G01N2035/041 , G01N2035/0465 , G01N2035/0477
摘要： A coupling ring (13), which on its underside has a plurality of permanent magnets (16) that are preferably disposed concentrically and with angular offset, and which is disposed laterally on that part of the transport device which is moved in the Z direction, serves to temporarily couple an instrument (10) or tool onto a transport mechanism. The coupling ring cooperates with a coupling plate (17), which is disposed on the upper side of the respective instrument to be coupled-on, and which has permanent magnets (19) of correspondingly opposite polarity disposed with the same distribution.
摘要翻译：耦合环（13）在其下侧具有多个永久磁铁（16），所述多个永磁体优选地同心地并且具有角偏移地设置，并且横向设置在沿Z方向移动的输送装置的该部分上，用于将仪器（10）或工具临时耦合到传送机构上。联接环与联接板（17）配合，联接板（17）设置在要耦合的相应仪器的上侧，并具有以相同分布布置的相应极性的永磁体（19）。

8. 发明授权

US10001431B2 Extraction device 有权
公开(公告)号：US10001431B2
公开(公告)日：2018-06-19
申请号：US14172545
申请日：2014-02-04
申请人： CTC Analytics AG
发明人： Kai Heinrich Schueler , Christophe Schillig
IPC分类号： G01N1/00 , G01N1/40 , G01N1/08 , G01N1/22 , G01N30/00
CPC分类号： G01N1/405 , G01N1/08 , G01N1/2226 , G01N2030/009 , Y10T436/255
摘要： A device (1) for extracting an extraction material, in particular for solid-phase micro-extraction, comprises an extractor (130) and a tip (100) for penetrating a separating layer, wherein the extractor (130) is connected to the tip (100). In a method for extracting an extraction material from a container with an extraction device (1), a separating layer of the container is penetrated by a tip (100) of an extractor (130), and the extraction material is extracted.

9. 发明授权

US08695444B2 Tool for handling a sample 有权
标题翻译：用于处理样品的工具
公开(公告)号：US08695444B2
公开(公告)日：2014-04-15
申请号：US12814169
申请日：2010-06-11
申请人： Roland Hiltbrand
发明人： Roland Hiltbrand
IPC分类号： G01N1/14
CPC分类号： G01N35/1002 , G01N30/24 , G01N35/00871 , G01N35/0099 , G01N35/1009 , G01N35/1065 , G01N35/1072 , G01N35/1079 , G01N35/1081 , G01N35/109 , G01N2035/00346
摘要： In the case of a tool (140) for handling a sample, which comprises a fastening device (141) for detachably fastening the tool to a tool holder of a sample handling apparatus, and comprises a sample manipulation device, for example realized as a syringe (150), fastened to the fastening device (141), this tool comprises a holding device, for example in the form of a needle guide (160), which, on the one hand, is fastened to the fastening device (141) so as to be movable in a coupling direction (165) and, on the other hand, can be coupled to and decoupled from the tool holder in the coupling direction (165).
摘要翻译：在用于处理样品的工具（140）的情况下，其包括用于将工具可拆卸地紧固到样品处理装置的工具架上的紧固装置（141），并且包括样品操作装置，例如实现为注射器（150），其紧固到所述紧固装置（141），所述工具包括保持装置，所述保持装置例如是针引导件（160）的形式，所述保持装置一方面被紧固到所述紧固装置（141），从而可以在联接方向（165）上移动，另一方面，可以在联接方向（165）上联接到工具架上并与工具夹分离。

10. 发明申请

US20140030818A1 SOLID-PHASE MICROEXTRACTION 审中-公开
标题翻译：固相微萃取
公开(公告)号：US20140030818A1
公开(公告)日：2014-01-30
申请号：US13953389
申请日：2013-07-29
申请人： CTC Analytics AG
发明人： Kai Heinrich SCHUELER , Melchior ZUMBACH
IPC分类号： G01N1/40
CPC分类号： G01N1/405 , G01N1/2214 , Y10T436/255
摘要： In a method for performing a solid-phase micro-extraction, a holding device connected to an extraction device and secured on an adapter is held, while an actuating device connected to a guide device is moved. A device for performing a solid-phase microextraction comprises an actuating device connected to a guide device, and a holding device connected to an extraction device, wherein the extraction device is guided at least partially in the guide device, and wherein the extraction device is movable relative to the guide device by means of an actuation of the actuating device.
摘要翻译：在执行固相微萃取的方法中，保持连接到提取装置并固定在适配器上的保持装置，同时连接到引导装置的致动装置移动。用于执行固相微萃取的装置包括连接到引导装置的致动装置和连接到提取装置的保持装置，其中所述提取装置至少部分地被引导到所述引导装置中，并且其中所述提取装置是可移动的通过致动装置的致动相对于引导装置。

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