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1. 发明授权

US11154704B2 Heart assist system and methods 有权
公开(公告)号：US11154704B2
公开(公告)日：2021-10-26
申请号：US15847338
申请日：2017-12-19
申请人： Circulite, Inc.
发明人： Robert C. Farnan , Robert G. Hudgins , John Dockter
IPC分类号： A61M60/857 , A61M60/148 , A61M60/205
摘要： A system for drawing blood from a heart of a patient, includes a blood pump, an outflow cannula and a flexible cannula assembly. The cannula assembly further includes a flexible cannula body including a proximal end, a distal end, an inner wall defining a lumen, and an outer wall. A tip is coupled with the distal end of the cannula body, and an anchor is coupled to the tip. The anchor is configured to engage an internal structure of the heart and resists movement of the cannula assembly in at least one direction along the flexible cannula body. A ring member is configured to be coupled to the heart wall and is positioned at least partially around the outer wall of the cannula body proximally relative to the tip. The ring member is further configured to provide hemostasis between the heart wall and the cannula body.

2. 发明授权

US10449274B2 System and method of facilitating connection between cannulae and a blood pump 有权
公开(公告)号：US10449274B2
公开(公告)日：2019-10-22
申请号：US14313270
申请日：2014-06-24
申请人： CircuLite, Inc.
发明人： Bryan P. Fritz , Robert C. Farnan , Andrew J. Dusbabek , Oliver Marseille , Murat Camkiran , Grant Thompson , Scott A. Olson
IPC分类号： A61M1/10 , A61M1/36 , A61B17/04 , A61B17/34 , A61M1/12 , A61B17/32 , A61M25/01
摘要： A system for facilitating fluid connection between cannulae and a blood pump. The system includes a cannula having proximal and distal ends. The distal end of the cannula adapted to be in fluid communication with the circulatory system. The proximal end of the cannula configured to couple to an inlet of the blood pump. The system further includes a tunneling device configured to be inserted into a body of a patient to direct the proximal end of the cannula adjacent to the inlet for connection thereto. The cannula further includes a first connecting structure. The tunneling device further includes a second connecting structure. The first and second connecting structures are selectively engageable to allow connection and disconnection between the cannula and tunneling device.

3. 发明授权

US10350384B2 Two-piece transseptal cannula, delivery system, and method of delivery 有权
公开(公告)号：US10350384B2
公开(公告)日：2019-07-16
申请号：US14191792
申请日：2014-02-27
申请人： CircuLite, Inc.
发明人： Robert C. Farnan , Scott A. Olson , Elizabeth Jung , Andrew J. Dusbabek , Robert G. Hudgins
IPC分类号： A61M1/10 , A61M25/00 , A61M1/36 , A61M25/04 , A61M29/00 , A61M1/12 , A61B17/34 , A61M25/02
摘要： A cannula assembly for directing blood from the heart of a patient and a minimally invasive method of implanting the same. The cannula assembly includes a flexible cannula body having a proximal end and a distal end with a receiving portion, and a transseptal tip having a distal end and a proximal end with an engaging portion. First and second anchors are coupled to the transseptal tip and configured to be deployed from a contracted state to an expanded state. The engaging portion of the transseptal tip is operable to removably engage the receiving portion of the flexible cannula body in vivo.

4. 发明授权

US10265501B2 Malleable Cannula 有权
公开(公告)号：US10265501B2
公开(公告)日：2019-04-23
申请号：US15718629
申请日：2017-09-28
申请人： CircuLite, Inc.
发明人： Robert C. Farnan , Arielle Drummond
IPC分类号： A61M25/00 , A61M1/10 , A61M5/142 , A61M1/12
摘要： A malleable cannula (50) for fluidically coupling with an anatomical structure includes a flexible cannula body wall (64) having a proximal end (68), a distal end (70), and a lumen (72) extending longitudinally between the proximal end (68) and the distal end (70). The proximal end (68) defines a first opening (80) to the lumen (72) and the distal end (70) defining a second opening (82) to the lumen (72). A channel is defined by a portion of the cannula body wall and extends longitudinally from the distal end (70) toward the proximal end (68). The channel has a first end oriented toward the proximal end of the cannula body wall. A malleable member (100) is provided within the channel and is fixedly connected to the cannula body wall (64) at the first end of the channel. The malleable member (100) is configured to assume and maintain a formed shape of the cannula body wall (64).

5. 发明授权

US09717830B2 Inflow cannula and blood flow assist system 有权
公开(公告)号：US09717830B2
公开(公告)日：2017-08-01
申请号：US14924842
申请日：2015-10-28
申请人： CircuLite, Inc.
发明人： Robert C. Farnan
IPC分类号： A61N1/362 , A61M1/10 , A61M1/12 , A61M25/04 , A61M25/09 , A61M25/10
CPC分类号： A61M1/1008 , A61M1/122 , A61M25/04 , A61M25/09 , A61M25/10
摘要： A system and method of drawing blood from the heart of a patient. The system includes a blood pump, an outflow cannula, and a flexible cannula assembly. The flexible cannula assembly includes a cannula body, a tip, and first and second anchors. The cannula body includes a proximal end coupled to the inlet of the blood pump, a distal end including a first locking element coupled to the tip. The first anchor has a first plurality of arms and is coupled to the tip and adapted to engage the internal surface of the heart wall. The second anchor includes a second plurality of arms and a second locking element and is slidably positioned on the outer wall of the cannula body and adapted to engage the first locking element of the distal end of the cannula body to couple the second anchor to the external surface of the heart wall.

6. 发明授权

US09028393B2 Coaxial balloon delivery device and method of delivering a transseptal cannula to a heart 有权
标题翻译：同轴气囊输送装置和将经血管套管输送到心脏的方法
公开(公告)号：US09028393B2
公开(公告)日：2015-05-12
申请号：US13888641
申请日：2013-05-07
申请人： CircuLite, Inc.
发明人： Robert C. Farnan
IPC分类号： A61M25/10 , A61M1/10 , A61M25/04 , A61M27/00 , A61M1/12 , A61M25/00 , A61M25/01 , A61M25/06
CPC分类号： A61M1/122 , A61M1/10 , A61M1/1008 , A61M1/101 , A61M25/005 , A61M25/0069 , A61M25/0074 , A61M25/0082 , A61M25/0097 , A61M25/0194 , A61M25/04 , A61M25/1006 , A61M25/10182 , A61M27/00 , A61M2025/0681 , A61M2025/1061
摘要： A transseptal cannula having a flexible cannula body, a left atrial anchor coupled to the distal end of the flexible cannula body, and a right atrial anchor operable to be attached to the left atrial anchor in vivo. The left and right atrial anchors are implanted and deployed separately. Delivery of the transseptal cannula to a heart tissue can include a low profile coaxial balloon catheter comprising a tube body including an inner member and an outer member surrounding the inner member and thereby creating an inflation channel between the inner and outer members, a hub coupled to the proximal portion of the tube body and including a fluid space in fluid communication with the inflation channel; and a balloon coupled to the distal portion of the tube body, wherein the balloon is in fluid communication with the inflation channel. The hub of the coaxial balloon catheter is constructed with a low profile so that other surgical devices can be directed over the coaxial hub without deflating and removing the balloon.
摘要翻译：经套管，其具有柔性插管主体，耦合到柔性插管主体的远端的左心房锚和可操作以在体内附接到左心房锚的右心房锚。左心房和右心房锚点分别植入和展开。将经血管套管递送到心脏组织可以包括薄型同轴气囊导管，其包括管体，该管体包括内部构件和围绕内部构件的外部构件，从而在内部构件和外部构件之间形成充气通道，管体的近端部分并且包括与膨胀通道流体连通的流体空间; 以及气囊，其联接到所述管体的远端部分，其中所述气囊与所述充气通道流体连通。同轴气囊导管的轮毂被构造成具有低轮廓，使得其他手术装置可以被引导到同轴轮毂上，而不会放气和移除气囊。

7. 发明申请

US20140257018A1 MALLEABLE CANNULA 审中-公开
标题翻译：可恶性肛门
公开(公告)号：US20140257018A1
公开(公告)日：2014-09-11
申请号：US13788039
申请日：2013-03-07
申请人： CIRCULITE, INC.
发明人： Robert C. Farnan
IPC分类号： A61M1/10
摘要： A malleable cannula. The malleable cannula includes a polymeric jacket and a malleable member. The malleable member, being surrounded by the jacket, includes a proximal end, a distal end, and a lumen extending therebetween and along a lengthwise axis of the malleable cannula. The malleable member further includes a longitudinal strut that is parallel to the lengthwise axis and a plurality of transverse struts coupled to and extending laterally away from the longitudinal strut and at least a portion of the lumen. The malleable member is configured to assume and maintain a shape of the malleable cannula.
摘要翻译：有韧性的插管。可延展插管包括聚合物护套和可延展构件。由护套包围的可延展构件包括近端，远端和在其间延伸并且沿着可延展套管的纵向轴线延伸的内腔。可延展构件还包括平行于纵向轴线的纵向支柱和耦合到纵向支柱和横向远离纵向支柱以及内腔的至少一部分的多个横向支柱。可塑性构件构造成承担并保持可延展套管的形状。

8. 发明申请

US20130338426A1 CANNULA FOR HEART CHAMBER IMPLANTATION AND RELATED SYSTEMS AND METHODS 审中-公开
公开(公告)号：US20130338426A1
公开(公告)日：2013-12-19
申请号：US13974334
申请日：2013-08-23
申请人： CircuLite, Inc.
发明人： Oliver Marseille , Walid Aboulhosn
IPC分类号： A61M1/12
CPC分类号： A61M1/12 , A61B17/3421 , A61B2017/00252 , A61B2017/3425 , A61B2017/3488 , A61M1/1008 , A61M25/0068 , A61M25/0074 , A61M25/008 , A61M25/04
摘要： A cannula for implantation into a chamber of a heart includes an elongate body having a lumen extending along a longitudinal axis, a first end, and a second end. The first and second ends define openings into the lumen and the second end includes a flat portion. A flared tip portion extends from the flat portion of the second end in a direction toward the first end, and flares radially outward from the longitudinal axis and in such direction. A ring member extends around the axis of the elongate body and is spaced from the flared tip portion, and the ring member is adapted for retaining the elongate body in a position relative to a wall of the chamber. An embodiment of a flared tip portion may further include a barbed surface configured to contact tissue around an aperture in the wall of the heart when the cannula travels through the aperture.

9. 发明授权

US08460168B2 Transseptal cannula device, coaxial balloon delivery device, and methods of using the same 有权
标题翻译：经血管套管装置，同轴气囊输送装置及其使用方法
公开(公告)号：US08460168B2
公开(公告)日：2013-06-11
申请号：US12720012
申请日：2010-03-09
申请人： Robert C. Farnan
发明人： Robert C. Farnan
IPC分类号： A61N1/362
CPC分类号： A61M1/122 , A61M1/10 , A61M1/1008 , A61M1/101 , A61M25/005 , A61M25/0069 , A61M25/0074 , A61M25/0082 , A61M25/0097 , A61M25/0194 , A61M25/04 , A61M25/1006 , A61M25/10182 , A61M27/00 , A61M2025/0681 , A61M2025/1061
摘要： A transseptal cannula having a flexible cannula body, a left atrial anchor coupled to the distal end of the flexible cannula body, and a right atrial anchor operable to be attached to the left atrial anchor in vivo. The left and right atrial anchors are implanted and deployed separately. Delivery of the transseptal cannula to a heart tissue can include a low profile coaxial balloon catheter comprising a tube body including an inner member and an outer member surrounding the inner member and thereby creating an inflation channel between the inner and outer members, a hub coupled to the proximal portion of the tube body and including a fluid space in fluid communication with the inflation channel; and a balloon coupled to the distal portion of the tube body, wherein the balloon is in fluid communication with the inflation channel. The hub of the coaxial balloon catheter is constructed with a low profile so that other surgical devices can be directed over the coaxial hub without deflating and removing the balloon.
摘要翻译：经套管，其具有柔性插管主体，耦合到柔性插管主体的远端的左心房锚和可操作以在体内附接到左心房锚的右心房锚。左心房和右心房锚点分别植入和展开。将经血管套管递送到心脏组织可以包括薄型同轴气囊导管，其包括管体，该管体包括内部构件和围绕内部构件的外部构件，从而在内部构件和外部构件之间形成充气通道，管体的近端部分并且包括与膨胀通道流体连通的流体空间; 以及气囊，其联接到所述管体的远端部分，其中所述气囊与所述充气通道流体连通。同轴气囊导管的轮毂被构造成具有低轮廓，使得其他手术装置可以被引导到同轴轮毂上，而不会放气和移除气囊。

10. 发明授权

US08343029B2 Transseptal cannula, tip, delivery system, and method 有权
标题翻译：经口插管，尖端，输送系统和方法
公开(公告)号：US08343029B2
公开(公告)日：2013-01-01
申请号：US12256911
申请日：2008-10-23
申请人： Robert C. Farnan , Scott A. Olson , Elizabeth Jung , Andrew J. Dusbabek , Robert G. Hudgins
发明人： Robert C. Farnan , Scott A. Olson , Elizabeth Jung , Andrew J. Dusbabek , Robert G. Hudgins
IPC分类号： A61N1/362 , A61N1/00 , A61M5/00 , A61F2/00
CPC分类号： A61M1/3653 , A61M1/1008 , A61M1/12 , A61M1/3659 , A61M1/3666 , A61M1/3667 , A61M25/04 , A61M25/10 , A61M2025/0233
摘要： A transseptal cannula assembly for directing blood from the heart of a patient and a minimally invasive method of implanting the same. The transseptal cannula assembly includes a flexible cannula body having proximal and distal portions with a lumen therebetween, a tip coupled to the distal portion of the flexible cannula body, and first and second anchors coupled to the tip. The anchors can be configured to be deployed from a contracted state to an expanded state and are configured to engage opposite sides of the heart tissue when in the expanded state. The anchors resist movement of the cannula assembly along a lengthwise central axis of the flexible cannula body.
摘要翻译：一种用于从患者心脏引导血液的经血管插管组件和一种植入其的微创方法。经插管组件包括柔性插管主体，其具有近端部分和远端部分，其间具有内腔，连接到柔性插管主体的远端部分的尖端以及联接到尖端的第一和第二锚固件。锚固件可以构造成从收缩状态展开到展开状态，并且构造成在处于展开状态时接合心脏组织的相对侧。锚固件抵抗插管组件沿着柔性插管主体的纵向中心轴线的运动。

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