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1. 发明授权

US08282568B2 Method for estimating cardiac pumping capacity 有权
标题翻译：估计心脏抽吸能力的方法
公开(公告)号：US08282568B2
公开(公告)日：2012-10-09
申请号：US12149400
申请日：2008-04-30
申请人： Ole Jakob Elle , Erik Fosse , Per Steinar Halvorsen
发明人： Ole Jakob Elle , Erik Fosse , Per Steinar Halvorsen
IPC分类号： A61B5/0402
CPC分类号： A61B5/029 , A61B5/1107 , A61B2562/0219 , A61N1/36578
摘要： A system and a method for estimating changes in cardiac pumping capacity in response to an intervention from data recorded by an accelerometer positioned on an outer surface of the heart. Interventions such as intravenous administration of nitroprusside, betablocker, epinephrine (adrenaline), or changes in the intravascular volume such as by fluid filling, are considered. It is shown that it is possible to directly correlate changes in cardiac pumping capacity to changes in parameters or graphical representation derived from signals characteristic to the acceleration an outer surface of the heart. In particular, it is shown how the effect of the interventions can be directly read from these parameters or graphical representations, and can thereby assist in decisions regarding the treatment of a cardiac surgery patient. The invention is preferably used in a post-surgery monitoring unit for surveillance of cardiac surgery patients.
摘要翻译：一种系统和方法，用于根据位于心脏外表面上的加速度计记录的数据进行干预，来估计心脏泵送能力的变化。考虑静脉内施用硝普钠，betablocker，肾上腺素（肾上腺素）或血管内体积变化（如通过液体灌注）等干预措施。显示了可以直接将心脏抽吸能力的变化与参考的变化或从心脏的外表面加速度特征的信号导出的图形表示相关联。特别地，示出了如何从这些参数或图形表示直接阅读干预的效果，从而可以帮助关于心脏手术患者的治疗的决定。本发明优选用于手术后监测单元，用于监控心脏手术患者。

2. 发明申请

US20090029979A1 5-HTX MODULATORS 审中-公开
标题翻译： 5-HTX调制器
公开(公告)号：US20090029979A1
公开(公告)日：2009-01-29
申请号：US11994738
申请日：2006-07-07
申请人： Jo Klaveness , Bjarne Brudeli , Finn Olav Levy
发明人： Jo Klaveness , Bjarne Brudeli , Finn Olav Levy
IPC分类号： A61K31/5365 , C07D209/04 , A61K31/404 , C07D401/06 , A61K31/517 , C07D401/04 , C07D405/14 , A61K31/496 , A61K31/4439 , A61K31/454 , C07D401/12 , C07D498/04
CPC分类号： C07D211/62 , C07D207/14 , C07D209/42 , C07D209/80 , C07D211/22 , C07D211/26 , C07D211/58 , C07D211/70 , C07D295/26 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D405/14 , C07D471/04
摘要： This invention relates to compounds which bind to serotonin receptors inside or outside the central nervous system, in particular compounds which bind to the 5-HT2 or 5-HT7 receptors, their preparation and use, compositions containing them, and methods of treatment using them.
摘要翻译：本发明涉及在中枢神经系统内部或外部结合血清素受体的化合物，特别是与5-HT2或5-HT7受体结合的化合物，其制备和用途，含有它们的组合物，以及使用它们的治疗方法。

3. 发明申请

US20080281214A1 Method for estimating cardiac pumping capacity 有权
标题翻译：估计心脏抽吸能力的方法
公开(公告)号：US20080281214A1
公开(公告)日：2008-11-13
申请号：US12149400
申请日：2008-04-30
申请人： Ole Jakob Elle , Erik Fosse , Per Steinar Halvorsen
发明人： Ole Jakob Elle , Erik Fosse , Per Steinar Halvorsen
IPC分类号： A61B5/02
CPC分类号： A61B5/029 , A61B5/1107 , A61B2562/0219 , A61N1/36578
摘要： The present invention provides a system and a method for estimating changes in cardiac pumping capacity in response to an intervention from data recorded by an accelerometer positioned on an outer surface of the heart. Interventions such as intravenous administration of nitroprusside, betablocker, epinephrine (adrenaline), or changes in the intravascular volume such as by fluid filling, are considered. It is shown that it is possible to directly correlate changes in cardiac pumping capacity to changes in parameters or graphical representation derived from signals characteristic to the acceleration an outer surface of the heart. In particular, it is shown how the effect of the interventions can be directly read from these parameters or graphical representations, and can thereby assist in decisions regarding the treatment of a cardiac surgery patient. The invention is preferably used in a post-surgery monitoring unit for surveillance of cardiac surgery patients.
摘要翻译：本发明提供了一种系统和方法，用于响应于由位于心脏外表面上的加速度计记录的数据的干预来估计心脏泵送能力的变化。考虑静脉内施用硝普钠，betablocker，肾上腺素（肾上腺素）或血管内体积变化（例如通过液体灌注）的干预措施。显示了可以直接将心脏抽吸能力的变化与参考的变化或从心脏的外表面加速度特征的信号导出的图形表示相关联。特别地，示出了如何从这些参数或图形表示直接阅读干预的效果，从而可以帮助关于心脏手术患者的治疗的决定。本发明优选用于手术后监测单元，用于监控心脏手术患者。

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