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1. 发明申请

US20200054842A1 TIP DETERMINER FOR AN INJECTION DEVICE 审中-公开
公开(公告)号：US20200054842A1
公开(公告)日：2020-02-20
申请号：US16610365
申请日：2018-05-03
申请人： ARES TRADING S.A.
发明人： Alim THAWER , Matthew J. HAYES , Quentin LE MASNE , Fabien JEANNEROT
IPC分类号： A61M5/42 , A61M5/32 , A61M5/20
摘要： A system determines the location of a tip of a hypodermic needle by moving a needle along a path, shining light from two sources onto respective portions of the path, and analysing signals received from the respective light sources that have been reflected by the needle.

2. 发明公开

US20240050563A1 Combination Treatment of Cancer 审中-公开
公开(公告)号：US20240050563A1
公开(公告)日：2024-02-15
申请号：US18251523
申请日：2021-11-01
申请人： Ares Trading S.A. , GlaxoSmithKline Intellectual Property (NO. 4) LTD.
发明人： Ada Sala-Hojman , Frank Czauderna , Ralph Lindemann , Roberta Ferretti , Shivapriya Ramaswamy
IPC分类号： A61K39/395 , A61P35/00 , A61K31/4709 , C07K16/28 , C07K14/71 , A61K38/17
CPC分类号： A61K39/3955 , A61P35/00 , A61K31/4709 , C07K16/2827 , C07K14/71 , A61K38/179 , C07K2319/30 , C07K2317/565 , A61K2039/505
摘要： The present disclosure relates to combination therapies useful for the treatment of cancer. In particular, the invention relates to the combined use of a PD-1 inhibitor, a TGF-beta inhibitor, and a MCT4 inhibitor to treat cancer.

3. 发明公开

US20230270629A1 DISPENSING CUP 审中-公开
公开(公告)号：US20230270629A1
公开(公告)日：2023-08-31
申请号：US18016110
申请日：2021-07-02
申请人： Ares Trading S.A.
发明人： Mike PATON , Theo KING , Darren SEYMOUR , Eric CHANIE , Francesco PIRAS
IPC分类号： A61J7/00 , A61J1/03 , B65D83/04 , B65D65/46 , B65D75/36 , B65D50/00 , B65D51/18 , B65D43/16
CPC分类号： A61J7/0046 , A61J1/035 , B65D83/0409 , B65D65/466 , B65D75/36 , B65D50/00 , B65D51/18 , B65D43/16 , B65D2251/0021 , B65D2251/0053 , B65D2251/1025 , B65D2251/105 , B65D2583/005 , B65D2543/00148
摘要： Described herein is dispensing cup for use with medicaments, which dispensing cup in use allows for the patient to (self) administer an oral medicament (tablet or capsule) without the need to come into direct (skin) contact with such medicament.

4. 发明公开

US20230152275A1 CAPILLARY GEL ELECTROPHORESIS AND ITS USE WITH COMPLEX BIOLOGICAL MOLECULES 审中-公开
公开(公告)号：US20230152275A1
公开(公告)日：2023-05-18
申请号：US17917430
申请日：2021-04-01
申请人： Ares Trading S.A.
发明人： Oscar Vassallo
IPC分类号： G01N27/447
CPC分类号： G01N27/44726
摘要： The invention described herein relates to an improved method for analytical capillary gel electrophoresis (CGE) for complex biologic molecules. The methods for the improved CGE include steps for the partial reduction of the biologic analyte molecule for use as calibration standard and use such partially reduced calibration sample to obtain an improved calibration curve for CGE to be used with biologic analyte molecules.

5. 发明授权

US11559634B2 Tip determiner for an injection device 有权
公开(公告)号：US11559634B2
公开(公告)日：2023-01-24
申请号：US16610365
申请日：2018-05-03
申请人： ARES TRADING S.A.
发明人： Alim Thawer , Matthew J. Hayes , Quentin Le Masne , Fabien Jeannerot
IPC分类号： A61M5/42 , A61M5/32 , A61M5/20
摘要： A system determines the location of a tip of a hypodermic needle by moving a needle along a path, shining light from two sources onto respective portions of the path, and analysing signals received from the respective light sources that have been reflected by the needle.

6. 发明申请

US20220354743A1 HOME STOCK MANAGEMENT SYSTEM 有权
公开(公告)号：US20220354743A1
公开(公告)日：2022-11-10
申请号：US17624403
申请日：2019-07-05
申请人： Ares Trading S.A.
发明人： Alessandro MACOR , Wim SAELEN
IPC分类号： A61J1/03 , G16H20/10 , G06K7/10
摘要： Described herein is a home stock management system (1) for packaged items comprising a stationary data collection module (10) configured to wirelessly collect data from one or more packaged items (11) and to transmit the collected data to a processing module (12) wherein the packaged item(s) (11) include(s) a wireless tag (15), a processing module (12) for receiving, storing and processing the collected data from the collection module (10), and a notification means (13), wherein, the data collection module (10) is configured to collect data from the one or more packaged items (11) present in the home without user intervention. The processing module (12) is configured to process the collected data to determine status information and the notification means (13) is configured to communicate to one or more authorized users the status information. The home stock management system (1) can be used for the monitoring of consumable packaged items in the house or for monitoring and managing the stock and use of medication in a patient home or residence.

7. 发明申请

US20220290259A1 NEW METHODS FOR SPECIES IDENTIFICATION 有权
公开(公告)号：US20220290259A1
公开(公告)日：2022-09-15
申请号：US17293493
申请日：2019-06-26
申请人： ARES TRADING S.A.
发明人： ALESSIA BACHMANN , FABIO LA NEVE
IPC分类号： C12Q1/6888
摘要： Provides herein is a method for identifying the specific cell lineage of cells in culture comprising the steps of determining from the nucleic acid molecules isolated from said recombinant cells in culture the presence of polymorphisms or SNPs at at least 5 different positions within at least five genes contained in said nucleic acid molecules, obtaining a genetic profile from the determination of the previous step, and identiyfing the cell lineage of said cells in culture from said genetic profile, and wherein the recombinant cells produce a recombinant protein.

8. 发明授权

US10526631B1 Method of reducing serine for asparagine misincorporation 有权
公开(公告)号：US10526631B1
公开(公告)日：2020-01-07
申请号：US15457597
申请日：2017-03-13
申请人： Ares Trading S.A.
发明人： Thomas Solacroup , Matthieu Stettler , Hervé Broly
IPC分类号： C12P21/02 , C07K16/24
摘要： The present invention relates to a method of reducing serine for asparagine misincorporation in a protein produced by a culture of cells in a cell culture method, the method comprising the addition of asparagine and iron to the cell culture medium.

9. 发明授权

US09534054B2 Monoclonal antibody directed against CXCR5 有权
标题翻译：针对CXCR5的单克隆抗体
公开(公告)号：US09534054B2
公开(公告)日：2017-01-03
申请号：US14787478
申请日：2014-04-30
申请人： ARES TRADING S.A.
发明人： Christine Power , Olivier Leger , Paul Bradfield , Horacio G. Nastri , Christel Iffland , Qi An
IPC分类号： A61K39/00 , A61K39/395 , A61K51/10 , C07K16/28
CPC分类号： C07K16/2866 , A61K39/00 , A61K39/395 , A61K2039/505 , C07K2317/21 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/732 , C07K2317/76 , C07K2317/92
摘要： The invention relates to monoclonal antibodies against human CXCR5 and to their use in the treatment of autoimmune or inflammatory diseases, as well as cancers.
摘要翻译：本发明涉及针对人CXCR5的单克隆抗体及其在治疗自身免疫性或炎性疾病以及癌症中的用途。

10. 发明授权

US09279014B2 Methods for preparing an active TNFR-Fc fusion protein 有权
标题翻译：制备活性TNFR-Fc融合蛋白的方法
公开(公告)号：US09279014B2
公开(公告)日：2016-03-08
申请号：US14239216
申请日：2012-08-17
申请人： Hye Soon Won , Byung Je Sung , Yong Ho Ahn , Sang Kyung Park
发明人： Hye Soon Won , Byung Je Sung , Yong Ho Ahn , Sang Kyung Park
IPC分类号： C07K14/705 , C07K14/715
CPC分类号： C07K14/70578 , C07K14/7151 , C07K2319/30
摘要： The present invention relates to a method for separating and preparing a TNFR-Fc fusion protein using hydrophobic interaction chromatography (HIC). More particularly, the present invention relates to a method for separating and preparing a highly pure active protein from clipped proteins due to displacement effect by adjusting the conductivity of a protein sample using a high concentration of salt solution and by adjusting a loading amount thereof, and a TNFR-Fc fusion protein prepared by the method.
摘要翻译：本发明涉及使用疏水相互作用色谱（HIC）分离和制备TNFR-Fc融合蛋白的方法。更具体地说，本发明涉及通过调节使用高浓度的盐溶液的蛋白质样品的电导率并调整其负载量，由于置换效应而从夹带蛋白质中分离和制备高纯度活性蛋白的方法，以及通过该方法制备的TNFR-Fc融合蛋白。

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