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1. 发明授权

US07182727B2 Single port cardiac support apparatus 失效
标题翻译：单口心脏支持装置
公开(公告)号：US07182727B2
公开(公告)日：2007-02-27
申请号：US11057273
申请日：2005-02-11
申请人： Walid Najib Aboul-Hosn
发明人： Walid Najib Aboul-Hosn
IPC分类号： A61M1/10
CPC分类号： A61M1/122 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/1086 , A61M1/125 , A61M25/1011 , A61M2205/32 , A61M2205/3334
摘要： A minimal intrusive cardiac support apparatus is disclosed which requires only one incision into a main blood vessel or heart chamber. The apparatus includes a pair of generally coaxial and slideably arranged cannulae (one inner and one outer) communicatively coupled to a blood pump for providing right-heart and/or left-heart cardiac support during cardiac surgery. Optional balloons may be mounted on the outside of the inner and outer conduits which can be selectively inflated to seal off the sides surrounding vessel or to deliver cooling fluid or medication to the surrounding tissue. Using the apparatus, a method of pumping blood through the body is also disclosed.
摘要翻译：公开了一种最小的侵入性心脏支持装置，其仅需要一个切口进入主血管或心室。该装置包括一对通常同轴且可滑动地布置的套管（一个内部和一个外部），其通信地联接到血液泵，用于在心脏手术期间提供右心脏和/或左心脏心脏支架。可选择的气球可以安装在内部和外部导管的外侧上，该导管可以选择性地膨胀以密封容器周围的侧面或将冷却流体或药物输送到周围组织。还公开了一种通过身体抽血的方法。

2. 发明授权

US07090659B2 Apparatus and methods for entering cavities of the body 失效
标题翻译：用于进入身体空腔的装置和方法
公开(公告)号：US07090659B2
公开(公告)日：2006-08-15
申请号：US10764664
申请日：2004-01-26
申请人： Walid N Aboul-Hosn , William R Kanz , Roland W Zieglier , Kelly J McCrystle , Rosalind Castor , Allan deDios
发明人： Walid N Aboul-Hosn , William R Kanz , Roland W Zieglier , Kelly J McCrystle , Rosalind Castor , Allan deDios
IPC分类号： A61H9/00
CPC分类号： A61M25/0043 , A61B2017/00243 , A61M1/3653 , A61M1/3659 , A61M1/3666 , A61M1/3667 , A61M25/0068 , A61M25/007 , A61M25/0074 , A61M25/0075
摘要： Systems and methods for providing cardiac support provide a cannula body having an inlet and an outlet. The cannula includes a preformed bend sized and configured to extend within the heart chamber between the inlet and the outlet. The cannula is inserted through a first valve into a heart chamber and through a second valve out of the heart chamber. Blood is drawn into the cannula through the inlet and discharged from the cannula through the outlet, thereby bypassing the heart chamber.
摘要翻译：用于提供心脏支架的系统和方法提供具有入口和出口的插管主体。套管包括预定的弯曲部，其大小和构造成在入口和出口之间的心室内延伸。插管通过第一阀插入心脏腔并通过第二阀离开心室。血液通过入口被吸入插管，并通过出口从插管排出，从而绕过心室。

3. 发明授权

US07022100B1 Guidable intravascular blood pump and related methods 有权
标题翻译：可引导血管内血液泵及相关方法
公开(公告)号：US07022100B1
公开(公告)日：2006-04-04
申请号：US10070178
申请日：2000-09-01
申请人： Walid N Aboul-Hosn , William R Kanz , Bruce Baker
发明人： Walid N Aboul-Hosn , William R Kanz , Bruce Baker
IPC分类号： A61M37/00 , A61M1/10
CPC分类号： A61M1/125 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/102 , A61M1/1029 , A61M1/1031 , A61M1/1034 , A61M1/1086 , A61M1/1096 , A61M1/122 , A61M25/09 , A61M2025/0177 , A61M2025/0183 , A61M2205/3348 , Y10S415/90
摘要： An improved intravascular blood pump system (10) and related methods involving the broad inventive concept of equipping the intravascular blood pump (12) with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
摘要翻译：改进的血管内血液泵系统（10）和涉及将血管内血液泵（12）装备为具有引导特征的广泛创造性概念的相关方法，使得血管内血液泵可以选择性地定位在患者的循环系统内的预定位置。

4. 发明申请

US20050228212A1 Pulmonary and circulatory blood flow support devices and methods for heart surgery procedures 审中-公开
标题翻译：肺和循环血流支持装置和心脏手术程序的方法
公开(公告)号：US20050228212A1
公开(公告)日：2005-10-13
申请号：US11142721
申请日：2005-06-01
申请人： Walid Aboul-Hosn , William Kanz
发明人： Walid Aboul-Hosn , William Kanz
IPC分类号： A61F2/82 , A61M1/10 , A61M1/12
CPC分类号： A61F2/82 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/122 , A61M1/125
摘要： Pump and cannula systems inserted through the right side and/or left side of the heart provide protection against collapse of the heart chambers and veins and arteries and provide supplemental blood flow through same to enable beating heart bypass surgery on all vessels of the heart, including lateral and posterior vessels. The invention eliminates the use of cardiopulmonary bypass (CPB) machines. The invention further provides stents adapted for protecting from vein, artery, atrium and/or ventricle collapse during beating heart bypass surgery.
摘要翻译：通过心脏的右侧和/或左侧插入的泵和套管系统提供防止心室和静脉和动脉的塌陷的保护，并且通过其提供补充血液流动，以便能够在心脏的所有血管上进行心脏旁路手术，包括外侧和后侧血管。本发明消除了使用体外循环（CPB）机器。本发明还提供了适于在搏动心脏旁路手术期间保护静脉，动脉，心房和/或心室塌陷的支架。

5. 发明授权

US6086570A Hemostasis valve with membranes having offset apertures 有权
标题翻译：具有偏移孔的膜的止血阀
公开(公告)号：US6086570A
公开(公告)日：2000-07-11
申请号：US163103
申请日：1998-09-29
申请人： Walid N. Aboul-Hosn , Dale Scribner
发明人： Walid N. Aboul-Hosn , Dale Scribner
IPC分类号： A61M39/06 , A61M5/14
CPC分类号： A61M39/0606
摘要： A self-sealing hemostasis valve having a first membrane with an opening offset from the center and a second membrane with an opening offset from the center in a direction opposite of the offset in the first membrane. The two membranes are joined about their outer edges. Access through the two elastomeric membranes without tearing is available at the intersection of the openings in the membrane assembly when the two membranes are deformed by an instrument being inserted through the hemostasis valve.
摘要翻译：一种自密封止血阀，其具有从中心偏离的开口的第一膜和第二膜，所述第二膜在与第一膜的偏移方向相反的方向上偏离中心。两个膜围绕其外边缘连接。当两个膜被插入通过止血阀的器械变形时，在膜组件的开口的相交处可以通过两个弹性膜进入，而不会撕裂。

6. 发明申请

US20060100565A1 Transport pump and organ stabilization apparatus including related methods 审中-公开
标题翻译：运输泵和器官稳定装置包括相关方法
公开(公告)号：US20060100565A1
公开(公告)日：2006-05-11
申请号：US11312087
申请日：2005-12-20
申请人： Walid Aboul-Hosn
发明人： Walid Aboul-Hosn
IPC分类号： A61M1/12
CPC分类号： A61M1/3653 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1086 , A61M1/122 , A61M1/125 , A61M1/3659 , A61M2205/32 , A61M2205/3334 , Y10S415/90
摘要： A surgical pump suitable for bodily fluids, normally blood, usable in the course of surgical interventions as an alternative to the traditional CPB (cardio pulmonary bypass) making use of external blood pumps. It consists of an intake cannula which is inserted with its fist (distal) end in a first vessel, an outflow cannula coaxial for some length with, and larger than the first cannula, which is inserted with its first (distal) end in a second vessel, both second ends of the coaxial cannulas being connected with a pump housing having an inlet for the inner cannula and outflow windows for the outer cannula, a rotor impeller housed in the housing and connected with an electric motor rotating coaxially below the pump housing, the housing having inner and outer passageways which allow inflow, change of flow direction (reversal) and outflow of the fluid, thus producing two coaxial counter flowing flows in the coaxial cannulas. The pump can be used making use of a single portal. Inflatable balloons can be used to stabilize the cannulas in situ and to stabilize the walls of the organs or vessels where the cannulas are inserted.
摘要翻译：一种适用于体液（通常为血液）的外科手术泵，可在外科手术过程中使用，作为使用外部血液泵的传统CPB（心脏肺动脉旁路）的替代方法。它由入口套管组成，其插入第一容器中的第一（远端）端，与第一套管一同长度同轴并且大于第一插管的流出插管，第一插管将第一插管的第一（远端）容器，同轴插管的两个第二端与具有用于内套管的入口和外插管的泵壳体连接，转子叶轮，其容纳在壳体中并与同轴地在泵壳体下方旋转的电动机连接，壳体具有允许流入的流动方向（反转）和流体流出的内部和外部通道，从而在同轴插管中产生两个同轴的对流流动。该泵可以使用单个门户使用。充气气球可用于在原位稳定插管，并稳定插入插管的器官或血管的壁。

7. 发明申请

US20050234288A1 Pulmonary and circulatory blood flow support devices and methods for heart surgery procedures 失效
标题翻译：肺和循环血流支持装置和心脏手术程序的方法
公开(公告)号：US20050234288A1
公开(公告)日：2005-10-20
申请号：US11136126
申请日：2005-05-24
申请人： Walid Aboul-Hosn , William Kanz
发明人： Walid Aboul-Hosn , William Kanz
IPC分类号： A61F2/82 , A61M1/10 , A61M1/12
CPC分类号： A61F2/82 , A61M1/1008 , A61M1/101 , A61M1/1034 , A61M1/122 , A61M1/125 , G06F19/00
摘要： Pump and cannula systems inserted through the right side and/or left side of the heart provide protection against collapse of the heart chambers and veins and arteries and provide supplemental blood flow through same to enable beating heart or still heart surgery, such as bypass surgery, on all vessels of the heart, including lateral and posterior vessels. Pump and cannula systems are provided for supporting pulmonary and/or circulatory blood flow external of the heart during any beating heart or still heart surgical procedure, including value repair or replacement. The invention eliminates the use of cardiopulmonary bypass (CPB) machines in all heart surgery and utilizes the patient's lung(s) for providing oxygenated blood during heart surgery. The invention further provides stents adapted for protecting from vein, artery, atrium and/or ventricle collapse during beating heart bypass surgery.
摘要翻译：通过心脏的右侧和/或左侧插入的泵和套管系统提供防止心室和静脉和动脉的塌陷的保护，并且通过它们提供补充的血液流动，以使得能够打心脏或静止心脏手术，例如旁路手术，在心脏的所有血管上，包括外侧和后侧血管。提供泵和套管系统，用于在任何跳动的心脏或静止心脏手术过程中支持心脏外部的肺和/或循环血流，包括价值修复或更换。本发明消除了在所有心脏手术中使用体外循环（CPB）机器，并利用患者的肺在心脏手术期间提供含氧血液。本发明还提供了适于在搏动心脏旁路手术期间保护静脉，动脉，心房和/或心室塌陷的支架。

8. 发明授权

US06926662B1 Left and right side heart support 有权
标题翻译：左右右心支持
公开(公告)号：US06926662B1
公开(公告)日：2005-08-09
申请号：US09868973
申请日：1999-12-23
申请人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
发明人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
IPC分类号： A61M1/10 , A61M1/36
CPC分类号： A61M1/3621 , A61M1/1008 , A61M1/101 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/3663
摘要： A cannulation system for cardiac support uses an inner cannula disposed within an outer cannula. The outer cannula includes a fluid inlet for placement within the right atrium of a heart. The inner cannula includes a fluid inlet extending through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart. The cannulation system also employs a pumping assembly coupled to the inner and outer cannulas to withdraw blood from the right atrium for delivery to the pulmonary artery to provide right heart support, or to withdraw blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support, or both.
摘要翻译：用于心脏支架的插管系统使用设置在外套管内的内套管。外套管包括用于放置在心脏右心房内的流体入口。内套管包括延伸穿过外套管和心房隔膜的流体入口的流体入口，用于放置在心脏的左心房和左心室中的至少一个中。插管系统还采用耦合到内插管和外插管的抽吸组件，以从右心房抽取血液以递送到肺动脉以提供正确的心脏支持，或者从左心房和左心室中的至少一个抽出血液输送到主动脉以提供左心脏支持，或两者兼而有之。

9. 发明申请

US20050119599A1 Supplemental port for catheter perfusion of surgical site and methods of use 审中-公开
标题翻译：导管灌注手术部位补充口及使用方法
公开(公告)号：US20050119599A1
公开(公告)日：2005-06-02
申请号：US10991255
申请日：2004-11-17
申请人： William Kanz , Walid Aboul-Hosn
发明人： William Kanz , Walid Aboul-Hosn
IPC分类号： A61M1/10 , A61M37/00
CPC分类号： A61M1/1022 , A61M1/10 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1018 , A61M1/102 , A61M1/122
摘要： A blood pump having a supplemental outflow port and/or a supplemental inflow port. A supplemental outflow port can be used to supply blood to regions of the body during heart bypass operations, such as to perfuse heart tissue downstream from an anastomosis site during CABG procedures so as to reduce the damage to the heart tissue. A supplemental inflow port can be used to infuse blood and/or various other fluids or compositions into the patient's blood stream, such as may be helpful or advantageous during emergency situations in cardiac surgery.
摘要翻译：具有补充流出口和/或补充流入口的血泵。可以使用补充流出口在心脏旁路手术期间向身体的区域供血，例如在CABG手术过程中灌注吻合部位下游的心脏组织，以减少对心脏组织的损伤。补充流入口可以用于将血液和/或各种其它流体或组合物注入到患者的血液中，例如在心脏手术中的紧急情况期间可能是有帮助或有利的。

10. 发明申请

US20020128672A1 Anastomosis system and related Methods 失效
标题翻译：吻合系统及相关方法
公开(公告)号：US20020128672A1
公开(公告)日：2002-09-12
申请号：US10068777
申请日：2002-02-05
申请人： A-Med Systems, Inc.
发明人： Fred Dinger , Paul Charbonneau
IPC分类号： A61F002/06
CPC分类号： A61B17/11 , A61B17/32053 , A61B2017/1135 , A61B2017/1139 , A61F2/064
摘要： Devices and methods for sealingly joining a graft vessel, such as a coronary bypass graft, to the side wall of a target vessel, such as the aorta or a coronary artery, in an anastomosis.
摘要翻译：用于将诸如冠状动脉旁路移植物的移植血管密封地连接到靶血管（例如主动脉或冠状动脉）的侧壁中的吻合装置和方法。

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