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1. 发明申请

US20060228793A1 Microsystem for separating serum from blood 审中-公开
标题翻译：用于从血液中分离血清的微系统
公开(公告)号：US20060228793A1
公开(公告)日：2006-10-12
申请号：US11348946
申请日：2006-02-06
申请人： Yoon-kyoung Cho , Tae-gon Kim , Seung-yong Hwang , Kwang-wook Oh , Jin-goo Park , Won-ho Ji
发明人： Yoon-kyoung Cho , Tae-gon Kim , Seung-yong Hwang , Kwang-wook Oh , Jin-goo Park , Won-ho Ji
IPC分类号： C12M1/34 , G01N9/30
CPC分类号： B01L3/502715 , B01L3/5021 , B01L3/502723 , B01L3/502753 , B01L2300/0861 , B01L2300/0867 , B01L2300/087 , B01L2400/0409
摘要： A microsystem for separating serum from blood using a centrifuge is provided. The microsystem includes various chambers and channels. When blood is injected into the channels and centrifuged, serum and blood cells in the injected blood are distributed into different chambers. Thus, the serum can be separated from the blood.
摘要翻译：提供了使用离心机从血液中分离血清的微系统。微系统包括各种室和通道。当将血液注入通道并离心时，注射血液中的血清和血细胞分布在不同的室中。因此，血清可以与血液分离。

2. 发明授权

US07329535B2 Apparatus for circulating carrier fluid 失效
标题翻译：载体流体循环装置
公开(公告)号：US07329535B2
公开(公告)日：2008-02-12
申请号：US10292012
申请日：2002-11-11
申请人： Kwang-wook Oh , Geun-bae Lim , Young-sun Lee , Yoon-kyoung Cho
发明人： Kwang-wook Oh , Geun-bae Lim , Young-sun Lee , Yoon-kyoung Cho
IPC分类号： C12M1/34 , C12M3/00 , F16K13/00 , B01L11/00 , B32B5/02
CPC分类号： B01L7/525 , B01L3/502738 , B01L2200/0673 , B01L2300/0816 , B01L2300/087 , B01L2300/1822 , B01L2300/185 , B01L2400/0421 , B01L2400/043 , B01L2400/0487 , B01L2400/0688 , B01L2400/0694 , Y10T137/4643 , Y10T137/4651
摘要： Provided are an apparatus for circulating a carrier fluid having two or more chambers or sections, an apparatus for amplifying a nucleic acid using the same, and a chip containing the same. The apparatus for circulating a carrier fluid includes two or more chambers maintained at different temperatures, each chamber having an inlet valve containing a pneumatic air pressure port for controlling inflow of the carrier fluid to the chamber (inlet pneumatic air pressure port), and an outlet valve containing a pneumatic air pressure for controlling outflow of the carrier fluid from the chamber (outlet pneumatic air pressure port), wherein the chambers are sequentially connected such that the outlet valve of one chamber is connected to the inlet valve of an adjacent chamber in a direction the fluid flows.
摘要翻译：提供一种用于循环具有两个或更多个室或部分的载体流体的装置，用于使用其的核酸的放大装置和含有该核酸的芯片的装置。用于循环载体流体的装置包括保持在不同温度的两个或更多个室，每个室具有入口阀，该入口阀包含用于控制载体流体流入室（进气气压端口）的气动空气压力端口，以及出口阀包含用于控制从腔室（出口气动空气压力端口）流出的载气的气动空气压力，其中腔室顺序地连接，使得一个室的出口阀连接到相邻室的入口阀方向流体流动。

3. 发明授权

US08697433B2 Polymerase chain reaction (PCR) module and multiple PCR system using the same 失效
标题翻译：聚合酶链反应（PCR）模块和多重PCR系统使用相同
公开(公告)号：US08697433B2
公开(公告)日：2014-04-15
申请号：US12843552
申请日：2010-07-26
申请人： Kwang-wook Oh , Jin-tae Kim , Kak Namkoong , Chin-sung Park , Yoon-kyoung Cho
发明人： Kwang-wook Oh , Jin-tae Kim , Kak Namkoong , Chin-sung Park , Yoon-kyoung Cho
IPC分类号： C12M1/00 , C12M1/36 , C12M1/38 , C12M1/34 , C12M3/00
CPC分类号： B01L7/52 , B01L3/502715 , B01L3/50851 , B01L2300/0627 , B01L2300/18
摘要： Provided are a PCR module and a multiple PCR system using the same. More particularly, provided are a PCR module with a combined PCR thermal cycler and PCR product detector, and a multiple PCR system using the same.
摘要翻译：提供了PCR模块和使用该PCR模块的多重PCR系统。更具体地，提供了具有组合的PCR热循环仪和PCR产物检测器的PCR模块，以及使用其的多重PCR系统。

4. 发明申请

US20050164281A1 Polymerase chain reaction (PCR) module and multiple PCR system using the same 有权
标题翻译：聚合酶链反应（PCR）模块和多重PCR系统使用相同
公开(公告)号：US20050164281A1
公开(公告)日：2005-07-28
申请号：US11080705
申请日：2005-03-15
申请人： Kwang-wook Oh , Jin-tae Kim , Kak Namkoong , Chin-sung Park , Yoon-kyoung Cho
发明人： Kwang-wook Oh , Jin-tae Kim , Kak Namkoong , Chin-sung Park , Yoon-kyoung Cho
IPC分类号： B01L3/00 , B01L7/00 , G01N21/03 , G01N21/64 , C12Q1/68 , C12M1/34 , G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： G01N21/6486 , B01L3/50851 , B01L7/52 , B01L2300/0627 , B01L2300/18 , G01N21/0332
摘要： Provided are a DNA PCR module and a multiple PCR system using the same. More particularly, provided are a DNA PCR module with a combined PCR thermal cycler and PCR product detector, and a multiple PCR system using the same.
摘要翻译：提供了DNA PCR模块和使用其的多重PCR系统。更具体地，提供了具有组合的PCR热循环仪和PCR产物检测器的DNA PCR模块，以及使用其的多重PCR系统。

5. 发明申请

US20060140051A1 Microfluidic device including microchannel on which plurality of electromagnets are disposed, and methods of mixing sample and lysing cells using the microfluidic device 审中-公开
标题翻译：微流体装置包括其上设置有多个电磁体的微通道，以及使用微流体装置混合样品和裂解细胞的方法
公开(公告)号：US20060140051A1
公开(公告)日：2006-06-29
申请号：US11285924
申请日：2005-11-22
申请人： Jin-tae Kim , Kwang-wook Oh , Yoon-kyoung Cho , Sang-hyun Peak , Sook-young Kim , Chin-sung Park , Kak Namkoong
发明人： Jin-tae Kim , Kwang-wook Oh , Yoon-kyoung Cho , Sang-hyun Peak , Sook-young Kim , Chin-sung Park , Kak Namkoong
IPC分类号： B01F13/08
CPC分类号： C12N1/066 , B01F13/0059 , B01F13/0809
摘要： Provided is a microfluidic device including at least one inlet, at least one outlet, and a microchannel connecting the inlet and the outlet. The microfluidic device includes two or more electromagnets disposed on sidewalls of the microchannel and oriented in a predetermined direction with respect to the direction in which the microchannel extends.
摘要翻译：提供了一种微流体装置，其包括连接入口和出口的至少一个入口，至少一个出口和微通道。微流体装置包括设置在微通道的侧壁上并相对于微通道延伸的方向在预定方向上定向的两个或多个电磁体。

6. 发明授权

US07209237B2 Optical system for analyzing multi-channel samples and multi-channel sample analyzer employing the same 有权
标题翻译：用于分析多通道样品的光学系统和采用该多通道样品的多通道样品分析仪
公开(公告)号：US07209237B2
公开(公告)日：2007-04-24
申请号：US11227385
申请日：2005-09-15
申请人： Gyeong-sik Ok , Yoon-kyoung Cho , Jin-tae Kim , Kwang-wook Oh
发明人： Gyeong-sik Ok , Yoon-kyoung Cho , Jin-tae Kim , Kwang-wook Oh
IPC分类号： G01N21/25
CPC分类号： G01N21/645
摘要： Provided are an optical system for analyzing multi-channel samples which uses a mirror rotating at high speeds and an aspherical mirror, and a multi-channel sample analyzer employing the optical system. The optical system for analyzing multi-channel samples, includes a light source unit which emits light traveling along an optical axis; a semi-spheroid aspherical mirror disposed in rotational symmetry about the optical axis; and an inclined mirror which reflects the light exiting the light source unit to the semi-spheroid aspherical mirror, while rotating about the optical axis, wherein an opening is formed in the center of the semi-spheroid aspherical mirror such that the light exiting the light source unit enters the inclined mirror through the semi-spheroid aspherical mirror.
摘要翻译：提供了一种用于分析使用高速旋转的反射镜的多通道样品和非球面镜的光学系统，以及采用该光学系统的多通道样本分析仪。用于分析多通道样品的光学系统包括发射沿着光轴行进的光的光源单元; 围绕光轴旋转对称设置的半球体非球面镜; 以及倾斜镜，其在围绕光轴旋转的同时将离开光源单元的光反射到半球形非球面镜，其中在半球镜非球面镜的中心形成开口，使得离开光的光源单元通过半球体非球面镜进入倾斜镜。

7. 发明授权

US07799557B2 Polymerase chain reaction (PCR) module and multiple PCR system using the same 有权
标题翻译：聚合酶链反应（PCR）模块和多重PCR系统使用相同
公开(公告)号：US07799557B2
公开(公告)日：2010-09-21
申请号：US11080705
申请日：2005-03-15
申请人： Kwang-wook Oh , Jin-tae Kim , Kak Namkoong , Chin-sung Park , Yoon-kyoung Cho
发明人： Kwang-wook Oh , Jin-tae Kim , Kak Namkoong , Chin-sung Park , Yoon-kyoung Cho
IPC分类号： C12M1/34 , C12M3/00
CPC分类号： G01N21/6486 , B01L3/50851 , B01L7/52 , B01L2300/0627 , B01L2300/18 , G01N21/0332
摘要： Provided are a DNA PCR module and a multiple PCR system using the same. More particularly, provided are a DNA PCR module with a combined PCR thermal cycler and PCR product detector, and a multiple PCR system using the same.
摘要翻译：提供了DNA PCR模块和使用其的多重PCR系统。更具体地，提供了具有组合的PCR热循环仪和PCR产物检测器的DNA PCR模块，以及使用其的多重PCR系统。

8. 发明授权

US07112452B2 Method and sensor for detecting the binding of biomolecules by shear stress measurement 有权
标题翻译：用于通过剪切应力测量检测生物分子的结合的方法和传感器
公开(公告)号：US07112452B2
公开(公告)日：2006-09-26
申请号：US10278691
申请日：2002-10-23
申请人： Yoon-kyoung Cho , Sun-hee Kim , Kwang-wook Oh , Geun-bae Lim , Dae-sung Yoon
发明人： Yoon-kyoung Cho , Sun-hee Kim , Kwang-wook Oh , Geun-bae Lim , Dae-sung Yoon
IPC分类号： G01N33/543
CPC分类号： C12Q1/6825 , Y10S436/806 , C12Q2565/107 , C12Q2565/607
摘要： A method and sensor are provided for detecting the binding of a probe and a target biomolecule by measuring a difference in the shear stress on the surface of the sensor before and after hybridization of the target molecule to the probe, such as nucleic acids or proteins. The shear stress may be measured sensitively and conveniently as an electrical signal without additional fluorescent labeling and without use of expensive additional devices.
摘要翻译：提供了一种方法和传感器，用于通过测量靶分子与探针如核酸或蛋白质杂交前后的传感器表面上的剪切应力差异来检测探针和靶生物分子的结合。剪切应力可以作为电信号被灵敏地和方便地测量，而不需要额外的荧光标记，而不使用昂贵的附加装置。

9. 发明授权

US08252569B2 Microfluidic device and method for concentration and lysis of cells or viruses 有权
标题翻译：用于细胞或病毒浓缩和溶解的微流控装置和方法
公开(公告)号：US08252569B2
公开(公告)日：2012-08-28
申请号：US13034857
申请日：2011-02-25
申请人： Yoon-kyoung Cho , Jeong-gun Lee , Sung-young Jeong
发明人： Yoon-kyoung Cho , Jeong-gun Lee , Sung-young Jeong
IPC分类号： C12N13/00 , C12N1/08 , G01N33/00
CPC分类号： B01L3/50273 , B01L3/502746 , B01L3/502761 , B01L2200/10 , B01L2300/1861 , B01L2400/0421 , B01L2400/0424 , B01L2400/043 , B01L2400/0439 , C12M47/02 , C12M47/04 , C12M47/06 , Y10T436/25 , Y10T436/2575
摘要： A microfluidic device for the concentration and lysis of cells or viruses and a method of concentrating and lysing cells or viruses using the microfluidic device include: magnetic beads, a reaction chamber in which the magnetic beads are accommodated and a laser source. The reaction chamber includes a plurality of electrodes which cross each other and are separated by a dielectric to generate an electric field and a vibrating part agitating the magnetic beads in the chamber. The laser source radiates a laser onto the magnetic beads in the reaction chamber.
摘要翻译：用于细胞或病毒的浓缩和裂解的微流体装置以及使用微流体装置浓缩和裂解细胞或病毒的方法包括：磁珠，容纳磁珠的反应室和激光源。反应室包括彼此交叉并被电介质隔开以产生电场的多个电极以及搅拌室中的磁珠的振动部分。激光源将激光辐射到反应室中的磁珠上。

10. 发明授权

US08057759B2 Microfluidic system and apparatus and method of controlling the same 有权
标题翻译：微流体系统及其控制方法
公开(公告)号：US08057759B2
公开(公告)日：2011-11-15
申请号：US11835461
申请日：2007-08-08
申请人： Jeong-gun Lee , Yoon-kyoung Cho , Beom-seok Lee , Jong-myeon Park
发明人： Jeong-gun Lee , Yoon-kyoung Cho , Beom-seok Lee , Jong-myeon Park
IPC分类号： B01L3/02 , B01L3/00 , G01N15/06 , G01N33/00
CPC分类号： B01L3/502715 , B01L3/5027 , B01L3/50273 , B01L3/502738 , B01L2200/14 , B01L2300/0806 , B01L2300/1861 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K99/0032 , F16K2099/0084 , F16K2099/0086 , G01N35/00069 , Y10T436/11 , Y10T436/25375 , Y10T436/2575
摘要： Provided are an apparatus and a method of controlling a microfluidic system, and the microfluidic system. The apparatus of controlling the microfluidic system includes a central control block controlling an operation of the microfluidic system, a rotator control block controlling a rotator, a position control block controlling the position of a moving unit, the moving unit moving to a position of the microfluidic structure, and a radiation energy source control block controlling energy of a radiation energy source, the radiation energy source using an electromagnetic wave to scan over a position of the microfluidic structure. Such a configuration allows effective control of a miniaturized portable microfluidic system.
摘要翻译：提供了一种控制微流体系统和微流体系统的装置和方法。控制微流体系统的装置包括控制微流体系统的操作的中央控制块，控制旋转器的旋转体控制块，控制移动单元的位置的位置控制块，移动到微流体位置的移动单元结构以及辐射能量源控制块，其控制辐射能源的能量，所述辐射能源使用电磁波扫描微流体结构的位置。这种配置允许有效地控制微型便携式微流体系统。

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