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    • 2. 发明授权
    • Substrate susceptor and deposition apparatus having same
    • 衬底感受器及其沉积设备
    • US09567673B2
    • 2017-02-14
    • US13811989
    • 2011-03-16
    • Yong Sung ParkSung Kwang LeeDong Yeul Kim
    • Yong Sung ParkSung Kwang LeeDong Yeul Kim
    • C23C16/46C23C16/455C23C16/458H01L21/67H01L21/687
    • C23C16/46C23C16/45551C23C16/45565C23C16/4581C23C16/4584H01L21/67109H01L21/68764H01L21/68771
    • The present disclosure relates to a deposition apparatus used to manufacture a semiconductor device including a process chamber; a substrate susceptor installed in the process chamber and including a plurality of concentrically arranged stages on which substrates are positioned; a plurality of members for supplying reaction gas; a member for supplying purge gas; a spray member including a plurality of baffles for independently spraying reaction gas and purge gas, supplied from the plurality of members supplying reaction gas and the member supplying purge gas, on the entirety of the treating surfaces of the substrate, in positions corresponding respectively to the substrates positioned on the stages; and a driving unit for rotating the substrate susceptor or the spray member in order for the baffles of the spray member to sequentially revolve each of the plurality of substrates positioned on the stages.
    • 本公开涉及一种用于制造包括处理室的半导体器件的沉积设备; 衬底基座,安装在所述处理室中并且包括多个同心布置的阶段,基板被放置在所述阶段上; 多个用于提供反应气体的构件; 供应吹扫气体的成员; 喷射构件,其包括多个挡板,用于独立地喷射反应气体和吹扫气体,所述反应气体和吹扫气体从供给反应气体的多个构件和供给吹扫气体的构件供给到基板的整个处理表面上,分别对应于 位于台架上的基板; 以及驱动单元,用于旋转基板基座或喷射构件,以便喷射构件的挡板顺序地旋转位于台上的多个基板中的每一个。
    • 4. 发明申请
    • SUBSTRATE SUSCEPTOR AND DEPOSITION APPARATUS HAVING SAME
    • 基板不锈钢和沉积装置
    • US20130118407A1
    • 2013-05-16
    • US13811989
    • 2011-03-16
    • Yong Sung ParkSung Kwang LeeDong Yeul Kim
    • Yong Sung ParkSung Kwang LeeDong Yeul Kim
    • C23C16/46
    • C23C16/46C23C16/45551C23C16/45565C23C16/4581C23C16/4584H01L21/67109H01L21/68764H01L21/68771
    • The present disclosure relates to a deposition apparatus used to manufacture a semiconductor device including a process chamber; a substrate susceptor installed in the process chamber and including a plurality of concentrically arranged stages on which substrates are positioned; a plurality of members for supplying reaction gas; a member for supplying purge gas; a spray member including a plurality of baffles for independently spraying reaction gas and purge gas, supplied from the plurality of members supplying reaction gas and the member supplying purge gas, on the entirety of the treating surfaces of the substrate, in positions corresponding respectively to the substrates positioned on the stages; and a driving unit for rotating the substrate susceptor or the spray member in order for the baffles of the spray member to sequentially revolve each of the plurality of substrates positioned on the stages.
    • 本公开涉及一种用于制造包括处理室的半导体器件的沉积设备; 衬底基座,安装在所述处理室中并且包括多个同心布置的阶段,基板被放置在所述阶段上; 多个用于提供反应气体的构件; 供应吹扫气体的成员; 喷射构件,其包括多个挡板,用于独立地喷射反应气体和吹扫气体,所述反应气体和吹扫气体从供给反应气体的多个构件和供给吹扫气体的构件供给到基板的整个处理表面上,分别对应于 位于台架上的基板; 以及驱动单元,用于旋转基板基座或喷射构件,以便喷射构件的挡板顺序地旋转位于台上的多个基板中的每一个。
    • 5. 发明申请
    • METHOD FOR PREDICTING ACTIVATION ENERGY USING ATOMIC FINGERPRINT DESCRIPTOR OR ATOMIC DESCRIPTOR
    • 使用原子指纹描述符或原子描述符预测激活能量的方法
    • US20120084012A1
    • 2012-04-05
    • US13277929
    • 2011-10-20
    • Ky Youb NamKyoung Tai NoDoo Nam KimWon Seok OhSung Kwang LeeJi Hoon JungKwang Hwi ChoChang Joon Lee
    • Ky Youb NamKyoung Tai NoDoo Nam KimWon Seok OhSung Kwang LeeJi Hoon JungKwang Hwi ChoChang Joon Lee
    • G06F19/10
    • G06F19/704G06F19/702G06F19/706G06F19/709
    • The present invention provides a method for constructing a database of atomic fingerprint descriptors. The invention provides a method for predicting activation energy using an atomic fingerprint descriptor and an atomic descriptor, the method comprising the steps of: (i) calculating the atomic fingerprint descriptor of a substrate; (ii) comparing the calculated atomic fingerprint descriptor with the constructed atomic fingerprint descriptor database to select an atomic position where cytochrome P450-mediated metabolism occurs; and (iii) predicting activation energy for the selected atomic position using an atomic descriptor. Also, the invention provides a method of predicting the activation energy of CYP450-mediated phase I metabolism using effective atomic descriptors. Specifically, the invention provides a method of predicting the activation energy either for cytochrome P450-mediated hydrogen abstraction or for tetrahedral intermediate formation in cytochrome P450-aromatic hydroxylation using equations including effective atomic descriptors.
    • 本发明提供了一种构建原子指纹描述符数据库的方法。 本发明提供一种使用原子指纹描述符和原子描述符来预测激活能的方法,该方法包括以下步骤:(i)计算衬底的原子指纹描述符; (ii)将计算的原子指纹描述符与构建的原子指纹描述符数据库进行比较,以选择细胞色素P450介导代谢发生的原子位置; 和(iii)使用原子描述符预测所选原子位置的活化能。 此外,本发明提供了使用有效原子描述符预测CYP450介导的I期代谢的活化能的方法。 具体地,本发明提供了一种使用包括有效原子描述符的方程式来预测细胞色素P450介导的氢提取或细胞色素P450-芳族羟基化中的四面体中间体形成的活化能的方法。
    • 7. 发明申请
    • METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR
    • US20110213558A1
    • 2011-09-01
    • US13001579
    • 2009-11-12
    • Ky Youb NamKyoung Tai NoDoo Nam KimWon Seok OhSung Kwang LeeJi Hoon JungKwang Hwi ChoChang Joon Lee
    • Ky Youb NamKyoung Tai NoDoo Nam KimWon Seok OhSung Kwang LeeJi Hoon JungKwang Hwi ChoChang Joon Lee
    • G06F19/00
    • G16C20/30G16C20/10G16C20/50G16C20/90
    • The present invention provides a method for constructing a database of atomic fingerprint descriptors. The invention provides a method for predicting activation energy using an atomic fingerprint descriptor and an atomic descriptor, the method comprising the steps of: (i) calculating the atomic fingerprint descriptor of a substrate; (ii) comparing the calculated atomic fingerprint descriptor with the constructed atomic fingerprint descriptor database to select an atomic position where cytochrome P450-mediated metabolism occurs; and (iii) predicting activation energy for the selected atomic position using an atomic descriptor. Also, the invention provides a method of predicting the activation energy of CYP450-mediated phase I metabolism using effective atomic descriptors. Specifically, the invention provides a method of predicting the activation energy either for cytochrome P450-mediated hydrogen abstraction or for tetrahedral intermediate formation in cytochrome P450-aromatic hydroxylation using equations including effective atomic descriptors. The method of the invention can rapidly predict activation energy for phase I metabolites at a practical level without having to perform a docking experiment between any additional CYP450 and the substrate, or a quantum mechanical calculation, thereby making it easier to develop new drugs using a computer. Also, the present invention may propose a strategy for increasing the bioavailability of drugs through the avoidance of metabolites based on the possibility of drug metabolism. Furthermore, the method of the present invention proposes new empirical approaches which can also be easily applied to activation energies for various chemical reactions, and makes it possible to explain physical and chemical factors that determine activation energy. In addition, through the prediction of activation energy according to the present invention, it is possible to predict i) metabolic products, ii) the relative rate of metabolism, iii) metabolic regioselectivity, iv) metabolic inhibition, v) drug-drug interactions, and vi) the toxicity of a metabolite.