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1. 发明申请

US20080262814A1 Method and system for generating a four-chamber heart model 有权
标题翻译：用于产生四室心脏模型的方法和系统
公开(公告)号：US20080262814A1
公开(公告)日：2008-10-23
申请号：US12082143
申请日：2008-04-09
申请人： Yefeng Zheng , Adrian Barbu , Bogdan Georgescu , Michael Lynch , Michael Scheuering , Dorin Comaniciu
发明人： Yefeng Zheng , Adrian Barbu , Bogdan Georgescu , Michael Lynch , Michael Scheuering , Dorin Comaniciu
IPC分类号： G06G7/60
CPC分类号： G06F19/3437 , G06F19/00 , G06F19/34 , G06T2207/30048 , G16H50/50
摘要： A method and system for building a statistical four-chamber heart model from 3D volumes is disclosed. In order to generate the four-chamber heart model, each chamber is modeled using an open mesh, with holes at the valves. Based on the image data in one or more 3D volumes, meshes are generated and edited for the left ventricle (LV), left atrium (LA), right ventricle (RV), and right atrium (RA). Resampling to enforce point correspondence is performed during mesh editing. Important anatomic landmarks in the heart are explicitly represented in the four-chamber heart model of the present invention.
摘要翻译：公开了一种用于从3D体积构建统计四室心脏模型的方法和系统。为了产生四腔心脏模型，每个腔室都使用开放的网格进行建模，在阀门处有孔。基于一个或多个3D体积中的图像数据，为左心室（LV），左心房（LA），右心室（RV）和右心房（RA）生成并编辑网格。在网格编辑期间执行重新采样以强制点对应。在本发明的四腔心脏模型中明确地表示心脏中的重要解剖学标志。

2. 发明授权

US09275190B2 Method and system for generating a four-chamber heart model 有权
标题翻译：用于产生四室心脏模型的方法和系统
公开(公告)号：US09275190B2
公开(公告)日：2016-03-01
申请号：US12082143
申请日：2008-04-09
申请人： Yefeng Zheng , Adrian Barbu , Bogdan Georgescu , Michael Lynch , Michael Scheuering , Dorin Comaniciu
发明人： Yefeng Zheng , Adrian Barbu , Bogdan Georgescu , Michael Lynch , Michael Scheuering , Dorin Comaniciu
IPC分类号： G06F19/00
CPC分类号： G06F19/3437 , G06F19/00 , G06F19/34 , G06T2207/30048 , G16H50/50
摘要： A method and system for building a statistical four-chamber heart model from 3D volumes is disclosed. In order to generate the four-chamber heart model, each chamber is modeled using an open mesh, with holes at the valves. Based on the image data in one or more 3D volumes, meshes are generated and edited for the left ventricle (LV), left atrium (LA), right ventricle (RV), and right atrium (RA). Resampling to enforce point correspondence is performed during mesh editing. Important anatomic landmarks in the heart are explicitly represented in the four-chamber heart model of the present invention.
摘要翻译：公开了一种用于从3D体积构建统计四室心脏模型的方法和系统。为了产生四腔心脏模型，每个腔室都使用开放的网格进行建模，在阀门处有孔。基于一个或多个3D体积中的图像数据，为左心室（LV），左心房（LA），右心室（RV）和右心房（RA）生成并编辑网格。在网格编辑期间执行重新采样以强制点对应。在本发明的四腔心脏模型中明确地表示心脏中的重要解剖学标志。

3. 发明授权

US08218845B2 Dynamic pulmonary trunk modeling in computed tomography and magnetic resonance imaging based on the detection of bounding boxes, anatomical landmarks, and ribs of a pulmonary artery 有权
标题翻译：基于检测边界框，解剖标志和肺动脉肋骨的计算机断层扫描和磁共振成像中的动态肺动脉造影
公开(公告)号：US08218845B2
公开(公告)日：2012-07-10
申请号：US12315343
申请日：2008-12-01
申请人： Michael Lynch , Razvan Ionasec , Bogdan Georgescu , Dorin Comaniciu , Dime Vitanovski
发明人： Michael Lynch , Razvan Ionasec , Bogdan Georgescu , Dorin Comaniciu , Dime Vitanovski
IPC分类号： G06K9/00 , A61B5/05
CPC分类号： G06T7/38 , G06T7/33 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/30048
摘要： A method and system for modeling the pulmonary trunk in 4D image data, such as 4D CT and MRI data, is disclosed. Bounding boxes are detected in frames of the 4D image data. Anatomic landmarks are detected in the frames of the 4D image data based on the bounding boxes. Ribs or centerlines of the pulmonary artery are detected in the frames of the 4D image data based on the anatomic landmarks, and a physiological pulmonary trunk model is fit the frames of the 4D image data based on the detected ribs and anatomic landmarks. The boundary of the pulmonary trunk is detected in order to refine the boundary of the pulmonary trunk model in the frames of the 4D image data, resulting in a dynamic model of the pulmonary trunk. The pulmonary trunk can be quantitatively evaluated using the dynamic model.
摘要翻译：公开了4D图像数据（如4D CT和MRI数据）对肺动脉干线进行建模的方法和系统。在4D图像数据的帧中检测边界框。基于边界框在4D图像数据的帧中检测解剖标志。基于解剖标志，在4D图像数据的帧中检测肺动脉的肋或中心线，并且基于检测到的肋和解剖标志将生理性肺动脉干模型拟合为4D图像数据的帧。检测肺动脉干的边界，以便在4D图像数据的帧中改善肺动脉干模型的边界，得到肺动脉的动态模型。可以使用动态模型定量评估肺动脉干。

4. 发明申请

US20090154785A1 Method and system for dynamic pulmonary trunk modeling in computed tomography and magnetic resonance imaging 有权
标题翻译：计算机断层扫描和磁共振成像中动态肺动脉造影的方法和系统
公开(公告)号：US20090154785A1
公开(公告)日：2009-06-18
申请号：US12315343
申请日：2008-12-01
申请人： Michael Lynch , Razvan Ionasec , Bogdan Georgescu , Dorin Comaniciu , Dime Vitanovski
发明人： Michael Lynch , Razvan Ionasec , Bogdan Georgescu , Dorin Comaniciu , Dime Vitanovski
IPC分类号： G06T7/00
CPC分类号： G06T7/38 , G06T7/33 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/30048
摘要： A method and system for modeling the pulmonary trunk in 4D image data, such as 4D CT and MRI data, is disclosed. Bounding boxes are detected in frames of the 4D image data. Anatomic landmarks are detected in the frames of the 4D image data based on the bounding boxes. Ribs or centerlines of the pulmonary artery are detected in the frames of the 4D image data based on the anatomic landmarks, and a physiological pulmonary trunk model is fit the frames of the 4D image data based on the detected ribs and anatomic landmarks. The boundary of the pulmonary trunk is detected in order to refine the boundary of the pulmonary trunk model in the frames of the 4D image data, resulting in a dynamic model of the pulmonary trunk. The pulmonary trunk can be quantitatively evaluated using the dynamic model.
摘要翻译：公开了4D图像数据（如4D CT和MRI数据）对肺动脉干线进行建模的方法和系统。在4D图像数据的帧中检测边界框。基于边界框在4D图像数据的帧中检测解剖标志。基于解剖标志，在4D图像数据的帧中检测肺动脉的肋或中心线，并且基于检测到的肋和解剖标志，生理性肺动脉干模型适合4D图像数据的帧。检测肺动脉干的边界，以便在4D图像数据的帧中改善肺动脉干模型的边界，得到肺动脉的动态模型。可以使用动态模型定量评估肺动脉干。

5. 发明申请

US20140117622A1 Curved Instrument for the Sport of Object Manipulation 审中-公开
标题翻译：对象操纵运动的弯曲仪器
公开(公告)号：US20140117622A1
公开(公告)日：2014-05-01
申请号：US13665468
申请日：2012-10-31
申请人： David Lynch , Michael Lynch
发明人： David Lynch , Michael Lynch
IPC分类号： A63B67/08
CPC分类号： A63B67/08 , A63B69/00
摘要： A Curved Instrument for the Sport of Object Manipulation is described as being a solid mold made of soft plastic which is used by but not limited to whirling, twirling, spinning, tossing, grasping, catching, bumping and flipping in the air to oneself, another person and among an unlimited number of persons with virtually any portion of the body. The present invention is composed of at least two portions attached to one another by a third portion where each portion contains at least one curve. A third portion also contains at least on curve with an addition of an indention located in the center of the portion for grip and reference point. The present invention has curves and indentions which makes the instrument safer and easier to use in the sport of object manipulation as the curved instrument is safer and easier to whirl, twirl, spin, toss, grasp, catch, bump and flip with virtually any portion of the body.
摘要翻译：用于对象操作的弯曲仪器被描述为由软塑料制成的实心模具，其被使用但不限于在空气中旋转，旋转，旋转，折腾，抓取，碰撞，碰撞和翻转，另一个人和无限数量的身体几乎任何部分的人。本发明由至少两个部分组成，其中每个部分包含至少一条曲线，第三部分彼此相连。第三部分至少在曲线上还包含位于该夹持部分和参考点部分的中心的凹槽。本发明具有曲线和凹痕，这使得仪器在对象操作的运动中更安全和更容易地使用，因为弯曲的乐器更安全，更容易旋转，旋转，旋转，折叠，抓住，捕捉，碰撞和翻转，几乎任何部分的身体。

6. 发明授权

US08710101B2 Co-crystals of agomelatine, a process for there preparation and pharmaceutical compositions containing them 有权
标题翻译： agomelatine的共晶体，其制备方法和含有它们的药物组合物
公开(公告)号：US08710101B2
公开(公告)日：2014-04-29
申请号：US13492095
申请日：2012-06-08
申请人： Philippe Letellier , Michael Lynch , Jean-Manuel Pean
发明人： Philippe Letellier , Michael Lynch , Jean-Manuel Pean
IPC分类号： A01N37/18 , A61K31/16 , C07C233/00 , C07C235/00 , C07C237/00 , C07C239/00
CPC分类号： C07C233/18 , A61K9/2018 , A61K9/2054 , C07B2200/13 , C07C55/06 , C07C55/08 , C07C55/12 , C07C57/145 , C07C59/265 , C07C65/03
摘要： New co-crystal of agomelatine composed of: agomelatine, or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide of formula (I) and an organic acid. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.
摘要翻译：由agomelatine或式（I）的N- [2-（7-甲氧基-1-萘基）乙基]乙酰胺和有机酸组成的新颖的agomelatine共晶体。含有该药物的药物可用于治疗褪黑激素系统的疾病。

7. 发明申请

US20130299230A1 High Voltage Cable and Insulator Shield 有权
标题翻译：高压电缆和绝缘体屏蔽
公开(公告)号：US20130299230A1
公开(公告)日：2013-11-14
申请号：US13466778
申请日：2012-05-08
申请人： Michael Lynch
发明人： Michael Lynch
IPC分类号： H02G7/00
CPC分类号： H01B17/00 , H02G7/00
摘要： A plastic shield for a cable and insulator is described having a center section for covering the insulator. The center section has an opening at both its ends for the cable. Proximate each opening is a pivotable flange, where the flange pivots at one end of the flange. An arm extends from each of the cable openings of the center section, and each arm covers the cable exiting the center section. Each arm is pivotally attached to the other end of the associated flange. The length of the flange will typically be about 2-3 inches. The flange allows its associated arm to be moved over a wide range of lateral angles (e.g., up to 45 degrees) and allows the arms to have a lateral offset relative to the center line of the center section and insulator to accommodate a cable that is offset from the center line.
摘要翻译：描述了一种用于电缆和绝缘体的塑料屏蔽件，其具有用于覆盖绝缘体的中心部分。中心部分的两端都有一个开口用于电缆。近似每个开口是可枢转的法兰，其中法兰在凸缘的一端枢转。臂从中心部分的每个电缆开口延伸，并且每个臂覆盖离开中心部分的电缆。每个臂可枢转地连接到相关法兰的另一端。凸缘的长度通常为2-3英寸。凸缘允许其相关联的臂在宽范围的横向角度（例如，最多45度）上移动，并且允许臂相对于中心部分和绝缘体的中心线具有横向偏移，以容纳电缆偏离中心线。

8. 发明申请

US20130267357A1 Curved Instrument for the Sport of Object Manipulation 审中-公开
标题翻译：对象操纵运动的弯曲仪器
公开(公告)号：US20130267357A1
公开(公告)日：2013-10-10
申请号：US13666129
申请日：2012-11-01
申请人： David Lynch , Michael Lynch
发明人： David Lynch , Michael Lynch
IPC分类号： A63B67/08
CPC分类号： A63B67/08
摘要： A Curved Instrument for the Sport of Object Manipulation is described as being a solid mold made of soft plastic which is used by but not limited to whirling, twirling, spinning, tossing, grasping, catching, bumping and flipping in the air to oneself, another person or among an unlimited number of persons with virtually any portion of the body. The present invention is composed of four portions attached to one another where each portion contains at least one curve in addition to an indention located in the center of the portion for grip and reference point. Each portion is identical to the other three portions and is a minor image of its respectable opposite portion. The present invention has curves and indentions which makes the instrument safer and easier to use in the sport of object manipulation as the curved instrument is safer and easier to whirl, twirl, spin, toss, grasp, catch, bump and flip with virtually any portion of the body.
摘要翻译：用于对象操作的弯曲仪器被描述为由软塑料制成的实心模具，其被使用但不限于在空气中旋转，旋转，旋转，折腾，抓取，碰撞，碰撞和翻转，另一个人或无限数量的身体几乎任何部分的人。本发明由彼此附接的四个部分组成，其中每个部分除了位于用于抓握和参考点的部分的中心的凹槽之外还包含至少一个曲线。每个部分与其他三个部分相同，并且是其相对相对部分的次要图像。本发明具有曲线和凹痕，这使得仪器在对象操作的运动中更安全和更容易地使用，因为弯曲的乐器更安全并且更容易旋转，旋转，旋转，折腾，抓住，捕捉，碰撞和翻转几乎任何部分的身体。

9. 发明申请

US20130167010A1 AUTOMATED GENERATION OF MULTIPLE VERSIONS OF A PUBLICATION 审中-公开
标题翻译：自动生成多个版本的出版物
公开(公告)号：US20130167010A1
公开(公告)日：2013-06-27
申请号：US13691377
申请日：2012-11-30
申请人： Shahriar Reza Karim , Michael Lynch
发明人： Shahriar Reza Karim , Michael Lynch
IPC分类号： G06F17/24
CPC分类号： G06F17/248 , G06F17/212 , G06F17/2247 , G06F17/2288
摘要： In one embodiment, a method for generating a publication is provided. The method includes determining a template for one or more pages of the publication. A structured document for the publication is generated where the structured document includes entry fields corresponding to the one or more addressable blocks. The structured document is then sent to one or more entities to allow users to input information for different versions of the publication. After the entities enter in information, a structured document is received from each of the plurality of entities. Information in the structured document refers to version information. A design application version of the structured document is then generated from the different structured documents received from the plurality of entities. The plurality of versions of the publication is then automatically generated.
摘要翻译：在一个实施例中，提供了一种用于生成出版物的方法。该方法包括确定出版物的一个或多个页面的模板。生成用于发布的结构化文档，其中结构化文档包括与一个或多个可寻址块相对应的输入字段。然后将结构化文档发送到一个或多个实体，以允许用户输入不同版本的发布的信息。在实体输入信息之后，从多个实体中的每一个接收结构化文档。结构化文档中的信息是指版本信息。然后，从从多个实体接收到的不同结构化文档生成结构化文档的设计应用版本。然后自动生成出版物的多个版本。

10. 发明申请

US20120061087A1 CONTINUOUS FLOW DRILLING SYSTEMS AND METHODS 有权
标题翻译：连续流动钻井系统和方法
公开(公告)号：US20120061087A1
公开(公告)日：2012-03-15
申请号：US13227260
申请日：2011-09-07
申请人： David Iblings , Thomas F. Bailey , R. K. Bansal , Adrian Steiner , Michael Lynch , Simon J. Harrall
发明人： David Iblings , Thomas F. Bailey , R. K. Bansal , Adrian Steiner , Michael Lynch , Simon J. Harrall
IPC分类号： E21B34/00 , E21B7/00
CPC分类号： E21B21/002 , E21B19/16 , E21B21/10 , E21B21/106 , E21B21/12 , E21B2034/005
摘要： A method for drilling a wellbore includes drilling the wellbore by injecting drilling fluid into a top of a tubular string disposed in the wellbore at a first flow rate and rotating a drill bit. The tubular string includes: the drill bit disposed on a bottom thereof, tubular joints connected together, a longitudinal bore therethrough, a port through a wall thereof, and a sleeve operable between an open position where the port is exposed to the bore and a closed position where a wall of the sleeve is disposed between the port and the bore. The method further includes moving the sleeve to the open position; and injecting drilling fluid into the port at a second flow rate while adding a tubular joint(s) to the tubular string. The injection of drilling fluid into the tubular string is continuously maintained between drilling and adding the joint(s).
摘要翻译：一种用于钻井井的方法包括：通过将钻井流体以第一流量喷射到设置在井筒中的管状柱的顶部中并旋转钻头来钻井孔。管柱包括：设置在其底部的钻头，连接在一起的管状接头，穿过其中的纵向孔，通过其壁的端口以及可在端口暴露于孔的打开位置和可关闭的位置之间操作的套筒套筒的壁设置在端口和孔之间的位置。该方法还包括将套筒移动到打开位置; 以及在第二流量下将钻井流体注入到所述端口中，同时向所述管状管道添加管状接头。在钻孔和加入接头之间，连续地保持将钻井液注入管柱中。

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