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    • 6. 发明申请
    • Historic View on Column Tables Using a History Table
    • 使用历史表的列表上的历史视图
    • US20120310934A1
    • 2012-12-06
    • US13153333
    • 2011-06-03
    • Thomas PehWolfgang StephanAndreas Tonder
    • Thomas PehWolfgang StephanAndreas Tonder
    • G06F17/30
    • G06F16/219
    • A computer-implemented system and method for providing an historical view of a data record are disclosed. A data record is stored in main memory of a server computer. An instruction to update the data record is received, and the instruction to update the data record is executed to provide a most recent version of the data record. A history table is generated that includes a main table part that represents the most recent version of the data record after the data record is updated, and a history table part that represents one or more past versions of the data record before the data record is updated. The history table is stored in the main memory of the server computer.
    • 公开了一种用于提供数据记录的历史视图的计算机实现的系统和方法。 数据记录存储在服务器计算机的主存储器中。 接收到更新数据记录的指令,执行更新数据记录的指令以提供数据记录的最新版本。 生成历史表,其包括在更新数据记录之后表示数据记录的最新版本的主表部分,以及在更新数据记录之前表示数据记录的一个或多个过去版本的历史表部分 。 历史记录表存储在服务器计算机的主存储器中。
    • 10. 发明授权
    • Method of preparing a sterile plasma-protein solution containing
fibrinogen and Factor XIII
    • 制备含有纤连蛋白和因子XIII的纯等离子体蛋白质溶液的方法
    • US5099003A
    • 1992-03-24
    • US256531
    • 1988-10-12
    • Ronald KotitschkeAxel W. StembergerWolfgang Stephan
    • Ronald KotitschkeAxel W. StembergerWolfgang Stephan
    • A61K35/14A61K38/00A61K38/16A61K38/43A61L2/00C07K14/435C07K14/745C07K14/75C12N9/10
    • C12N9/1044A61L2/0088C07K14/75A61K38/00
    • A method of preparing a sterile and stable plasma-protein solution containing fibrinogen and Factor XIII from human blood plasma which has been stabilized with citrate, comprising treating the plasma with .beta.-propiolactone and irradiating it with ultraviolet light, removing the Factors II, VII, IX and X by adsorption onto anion exchangers that adsorb proteins, precipitating the companion proteins out by adding ethanol until the solution has a final concentration of about 9% by volume at -3.degree. C., centrifuging the precipitate off, dissolving the precipitate in a citrate buffer at a pH of about 6.35 and a temperature of about 37.degree. C., adjusting the protein level of the solution to about 13.3 g/l with sodium citrate solution, adding ethanol, a glycine citrate buffer, and a solution of sodium citrate to precipitate out the companion proteins, adding ethanol to the remaining solution until the solution has a final concentration of about 9% by volume at -3.degree. C., thereby precipitating fribrinogen and Factor XIII, dissolving the precipitate in a citrate buffer at a pH of about 6.35 and a temperature of about 37.degree. C., and filtering the solution.
    • 一种制备含有已经用柠檬酸盐稳定的人血浆中的纤维蛋白原和因子XIII的无菌且稳定的血浆蛋白溶液的方法,包括用β-丙内酯处理血浆并用紫外线照射,除去因子II, IX和X通过吸附到吸附蛋白质的阴离子交换剂上,通过加入乙醇沉淀出伴侣蛋白,直到溶液在-3℃下具有约9体积%的终浓度,离心沉淀,将沉淀物溶解在 柠檬酸盐缓冲液,pH约6.35,温度约37℃,用柠檬酸钠溶液调节溶液的蛋白质水平至约13.3g / l,加入乙醇,柠檬酸甘氨酸缓冲液和柠檬酸钠溶液 沉淀出伴侣蛋白质,向剩余的溶液中加入乙醇直到溶液在-3℃下具有约9体积%的终浓度,从而沉淀 稀释蛋白原和因子XIII,将沉淀溶解在约6.35的pH和约37℃的柠檬酸盐缓冲液中,并过滤溶液。