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1. 发明申请

US20100189334A1 FUNDUS OCULI OBSERVATION DEVICE, FUNDUS OCULI IMAGE PROCESSING DEVICE, AND FUNDUS OCULI OBSERVATION METHOD 审中-公开
标题翻译：基金OCULI观察设备，FUNDUS OCULI图像处理设备和基金OCULI观察方法
公开(公告)号：US20100189334A1
公开(公告)日：2010-07-29
申请号：US12733559
申请日：2008-09-09
申请人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
发明人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
IPC分类号： G06K9/00
CPC分类号： A61B3/102 , A61B3/0058 , A61B3/1225 , A61B3/14
摘要： A fundus oculi observation device 1 has a function of forming a tomographic image of a fundus oculi Ef and a function of capturing a two-dimensional image of the surface of the fundus oculi Ef (a fundus oculi image Ef′). An arithmetic and control unit 200: specifies a vascular region in the tomographic image and a vascular region in the fundus oculi image Ef′; obtains a common region of the vascular region in the tomographic image and the vascular region in the fundus oculi image Ef′ and specifies the common region in the tomographic image; erases an image of the common region from the tomographic image and estimates a layer position within the common region to add an image representing this layer position to the common region; and obtains the layer thickness of the fundus oculi Ef in the common region based on the image representing this layer position.
摘要翻译：眼底观察装置1具有形成眼底Ef的断层图像和捕获眼底Ef（眼底图像Ef'）的表面的二维图像的功能的功能。算术和控制单元200：指定断层图像中的血管区域和眼底图像Ef'中的血管区域; 获取眼底图像中的血管区域的共同区域和眼底图像Ef'中的血管区域，并指定断层图像中的共同区域; 从断层图像中擦除公共区域的图像，并估计公共区域内的层位置，以将表示该层位置的图像添加到公共区域; 并且基于表示该层位置的图像，获得公共区域中眼底Ef的层厚度。

2. 发明授权

US08096658B2 Fundus oculi observation device and program for controlling the same 有权
标题翻译：眼底观察装置及其控制程序
公开(公告)号：US08096658B2
公开(公告)日：2012-01-17
申请号：US12600865
申请日：2008-04-08
申请人： Tsutomu Kikawa , Hiroyuki Aoki
发明人： Tsutomu Kikawa , Hiroyuki Aoki
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61B5/0059 , A61B3/102 , A61B5/0066 , G01N21/4795 , G01N21/64
摘要： A fundus oculi observation device 1 can form a near-infrared motion image and a color image (still image) of a fundus oculi Ef. The device 1 specifies an image region within the near-infrared motion image corresponding to a region of interest within the color image while the near-infrared motion image is being formed. The device 1 scans with a signal light LS based on the specified image region, thereby forming a tomographic image along the scanning line. According to the device 1, it is possible to determine a region of interest within a still image having a comparatively high image quality, specify the image region within the motion image corresponding to this region of interest, set a measurement site for the tomographic image.
摘要翻译：眼底观察装置1可以形成眼底Ef的近红外运动图像和彩色图像（静止图像）。设备1在形成近红外运动图像的同时指定与彩色图像内的感兴趣区域相对应的近红外运动图像内的图像区域。装置1基于指定的图像区域用信号光LS扫描，从而沿着扫描线形成断层图像。根据装置1，可以确定具有较高图像质量的静止图像内的感兴趣区域，指定与该感兴趣区域相对应的运动图像内的图像区域，设置断层图像的测量位置。

3. 发明授权

US07828437B2 Fundus oculi observation device and fundus oculi image processing device 有权
标题翻译：眼底观察装置和眼底图像处理装置
公开(公告)号：US07828437B2
公开(公告)日：2010-11-09
申请号：US12035879
申请日：2008-02-22
申请人： Tsutomu Kikawa , Takashi Fujimura , Hiroyuki Aoki , Jun Suehiro , Yasufumi Fukuma
发明人： Tsutomu Kikawa , Takashi Fujimura , Hiroyuki Aoki , Jun Suehiro , Yasufumi Fukuma
IPC分类号： A61B3/14
CPC分类号： G01B9/02044 , A61B3/102 , G01B9/0203 , G01B9/02083 , G01B9/02089 , G01B9/02091 , G01B2290/65
摘要： A fundus oculi observation device comprises: an image forming part configured to optically acquire data and form a tomographic image of a fundus oculi of an eye; a storage configured to store optical information representing a state of an ocular optical system of the eye; a calculator configured to calculate a magnification of the ocular optical system, based on the optical information; and an analyzer configured to analyze the tomographic image, based on the magnification.
摘要翻译：眼底观察装置包括：图像形成部，被配置为光学地获取数据并形成眼睛的眼底的断层图像; 存储器，被配置为存储表示眼睛的眼睛光学系统的状态的光学信息; 计算器，被配置为基于所述光学信息计算所述眼睛光学系统的倍率; 以及分析器，其被配置为基于所述放大率来分析所述断层图像。

4. 发明授权

US08348426B2 Optical image measurement device and image processing device 有权
标题翻译：光学图像测量装置和图像处理装置
公开(公告)号：US08348426B2
公开(公告)日：2013-01-08
申请号：US12052187
申请日：2008-03-20
申请人： Hisashi Tsukada , Hiroyuki Aoki , Yasufumi Fukuma , Tsutomu Kikawa
发明人： Hisashi Tsukada , Hiroyuki Aoki , Yasufumi Fukuma , Tsutomu Kikawa
IPC分类号： A61B3/14
CPC分类号： A61B3/102 , G01B9/0203 , G01B9/02044 , G01B9/02085 , G01B9/02087 , G01B9/02091 , G01B2290/65 , G06T3/4007
摘要： An optical image measurement device is configured to form a tomographic image at each of a plurality of cross sections of a measurement object, and the optical image measurement device comprises: an image processor configured to execute an arithmetic operation based on a tomographic image at one cross section of the plurality of cross sections and another tomographic image at each of one or more cross sections other than the one cross section, thereby forming a new tomographic image at the one cross section.
摘要翻译：光学图像测量装置被配置为在测量对象的多个横截面中的每一个处形成断层图像，并且所述光学图像测量装置包括：图像处理器，被配置为在一个十字交叉处执行基于断层图像的算术运算所述多个横截面的截面和在所述一个横截面以外的一个或多个横截面中的每一个处的另一断层图像，从而在所述一个横截面处形成新的断层图像。

5. 发明授权

US07905596B2 Fundus observation device, an ophthalmologic image processing unit, an ophthalmologic image processing program, and an ophthalmologic image processing method 有权
标题翻译：眼底观察装置，眼科图像处理单元，眼科图像处理程序和眼科图像处理方法
公开(公告)号：US07905596B2
公开(公告)日：2011-03-15
申请号：US11760314
申请日：2007-06-08
申请人： Hiroyuki Aoki , Takashi Fujimura , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
发明人： Hiroyuki Aoki , Takashi Fujimura , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
IPC分类号： A61B3/14 , A61B3/10 , A61B3/00
CPC分类号： A61B3/102 , G06T7/12 , G06T7/174 , G06T7/181 , G06T2207/10101 , G06T2207/30041
摘要： First image forming part forms a two-dimensional surface image of a fundus oculi of an eye based on optically obtained data. Second image forming part forms tomographic images of fundus oculi based on data obtained by optically scanning a region of the surface of fundus oculi corresponding to at least part of two-dimensional image. Accumulated image generating part generates an accumulated image by accumulating the formed tomographic images in a depth-wise direction. Extracting part extracts first vascular territory corresponding to a fundus oculi vessel from two-dimensional image formed by first image forming part, and also extracts second vascular territory corresponding to a fundus oculi vessel from accumulated image generated by accumulated image generating part. Specification part specifies a position of a vascular cross sectional region corresponding to a cross section of a fundus oculi vessel in the tomographic image based on extracted first vascular territory and extracted second vascular territory.
摘要翻译：第一图像形成部件基于光学获得的数据形成眼睛的眼底的二维表面图像。第二图像形成部分基于通过光学扫描与至少部分二维图像相对应的眼底表面的区域获得的数据来形成眼底的断层图像。累积图像生成部通过在深度方向累积形成的断层图像来生成累积图像。提取部分从由第一图像形成部分形成的二维图像中提取与眼底容器相对应的第一血管区域，并且从由累积图像生成部分生成的累积图像中提取与眼底容器对应的第二血管区域。规格部分基于提取的第一血管区域和提取的第二血管区域来指定与断层图像中的眼底血管的横截面对应的血管横截面区域的位置。

6. 发明授权

US07756311B2 Optical image measuring device, optical image measuring program, fundus observation device, and fundus observation program 有权
标题翻译：光学图像测量装置，光学图像测量程序，眼底观察装置和眼底观察程序
公开(公告)号：US07756311B2
公开(公告)日：2010-07-13
申请号：US11545270
申请日：2006-10-10
申请人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
发明人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
IPC分类号： G06K9/00 , G01B9/02
CPC分类号： G01N21/4795 , A61B3/102 , A61B3/145 , G01N2021/1787
摘要： An optical image measuring device which can form a highly reliable image even if an object moves during scanning of a signal light is provided. An optical image forming device 1 comprises: an interferometer that splits a low coherence light L0 into a signal light LS and a reference light LR and generates an interference light LC by overlaying the signal light LS reflected by a fundus oculi with the reference light LR reflected by a reference mirror 14; a CCD 34 which receives the interference light LC and outputs a detection signal; Galvanometer mirrors 22 and 23 to scan the signal light LS in a main scanning direction and a sub-scanning direction; and a computer 40 forming tomographic images G1 to Gm along the main scanning direction at different positions of the sub-scanning direction. The Galvanometer mirrors 22 and 23 scan the signal light LS in a given direction crossing the main scanning direction, and the computer 40 forms a tomographic image for correction GR along the given direction to correct displacement of each topographic image Gi based on the tomographic image for correction GR.
摘要翻译：提供了即使在信号光的扫描期间物体移动时也可以形成高可靠性图像的光学图像测量装置。光学图像形成装置1包括：干涉仪，其将低相干光L0分解成信号光LS和参考光LR，并通过将由眼底反射的信号光LS与反射的参考光LR重叠而产生干涉光LC 通过参考反射镜14; CCD34，其接收干涉光LC并输出检测信号; 电流计镜22和23在主扫描方向和副扫描方向扫描信号光LS; 以及在副扫描方向的不同位置沿着主扫描方向形成断层图像G1〜Gm的计算机40。电流计反射镜22和23沿与主扫描方向相交的给定方向扫描信号光LS，并且计算机40沿着给定方向形成用于校正GR的断层图像，以校正基于断层图像的每个地形图像Gi的位移校正GR。

7. 发明申请

US20070222946A1 Fundus Observation Device 有权
标题翻译：眼底观察装置
公开(公告)号：US20070222946A1
公开(公告)日：2007-09-27
申请号：US11689090
申请日：2007-03-21
申请人： Yasufumi Fukuma , Hiroyuki Aoki , Hisashi Tsukada , Tsutomu Kikawa
发明人： Yasufumi Fukuma , Hiroyuki Aoki , Hisashi Tsukada , Tsutomu Kikawa
IPC分类号： A61B3/14
CPC分类号： A61B3/102
摘要： Image forming part 220 forms a 2-dimensional image of the surface of the fundus oculi Ef (fundus oculi image) and a tomographic image of the fundus oculi Ef. The fundus oculi image 212a and the tomographic image Ga captured at the first examination time and the fundus oculi image 212b and the tomographic image Gb captured at the second examination time are stored in an image storage part 212. Position information generating part 214 generates the position information 213a indicating the position of the tomographic image Ga in the fundus oculi image 212a and the position information 213b indicating the position of the tomographic image Gb in the fundus oculi image 212b. The generated position information 213a and 213b are stored in information storage part 213. Image processing part 230 adjusts the position between the tomographic images Ga and Gb based on such position information 213a and 213b.
摘要翻译：图像形成部220形成眼底Ef（眼底图像）的表面的二维图像和眼底Ef的断层图像。在第一检查时间拍摄的眼底图像212a和眼底图像212b和在第二检查时间捕获的断层图像Gb被存储在图像存储部分212中。位置信息生成部214生成表示眼底图像212a中的断层图像Ga的位置的位置信息213a和表示眼底图像212b中的断层图像Gb的位置的位置信息213b。所生成的位置信息213a和213b被存储在信息存储部分213中。图像处理部分230基于这样的位置信息213a和213b来调整断层图像Ga和Gb之间的位置。

8. 发明授权

US08408704B2 Fundus oculi observation device, ophthalmologic image processing device, and program 有权
标题翻译：眼底观察装置，眼科图像处理装置和程序
公开(公告)号：US08408704B2
公开(公告)日：2013-04-02
申请号：US12733485
申请日：2008-09-09
申请人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
发明人： Atsuo Tomidokoro , Shinsuke Konno , Makoto Araie , Hiroyuki Aoki , Takashi Fujimura , Tsutomu Kikawa
IPC分类号： A61B3/14
CPC分类号： A61B3/102
摘要： A fundus oculi observation device capable of defining which part in the result of analysis of the layer thickness of a fundus oculi is a part obtained by analyzing a vascular region is provided. A fundus oculi observation device 1 forms a plurality of tomographic images G1-Gm of a fundus oculi Ef. A layer thickness distribution calculator 231 calculates layer thickness distribution of the fundus oculi Ef in a cross section of a tomographic image G based on the tomographic images G1-Gm. A vascular region specifying part 234 specifies a vascular region in the tomographic image G. A controller 210 controls a display 240A to display layer thickness distribution information representing the layer thickness distribution and to also display vascular position information representing the position of the vascular region on the layer thickness distribution information.
摘要翻译：本发明提供一种眼底观察装置，其能够确定眼底层厚度的分析结果中的哪一部分是通过分析血管区域获得的部分。眼底观察装置1形成眼底Ef的多个断层图像G1-Gm。层厚度分布计算器231基于断层图像G1-Gm计算断层图像G的横截面中眼底Ef的层厚度分布。血管区域指定部234指定断层图像G中的血管区域。控制器210控制显示器240A以显示表示层厚度分布的层厚度分布信息，并且还显示表示血管区域的位置的血管位置信息层厚度分布信息。

9. 发明授权

US07641338B2 Fundus observation device 有权
标题翻译：眼底观察装置
公开(公告)号：US07641338B2
公开(公告)日：2010-01-05
申请号：US11689090
申请日：2007-03-21
申请人： Yasufumi Fukuma , Hiroyuki Aoki , Hisashi Tsukada , Tsutomu Kikawa
发明人： Yasufumi Fukuma , Hiroyuki Aoki , Hisashi Tsukada , Tsutomu Kikawa
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61B3/102
摘要： Image forming part 220 forms a 2-dimensional image of the surface of the fundus oculi Ef (fundus oculi image) and a tomographic image of the fundus oculi Ef. The fundus oculi image 212a and the tomographic image Ga captured at the first examination time and the fundus oculi image 212b and the tomographic image Gb captured at the second examination time are stored in an image storage part 212. Position information generating part 214 generates the position information 213a indicating the position of the tomographic image Ga in the fundus oculi image 212a and the position information 213b indicating the position of the tomographic image Gb in the fundus oculi image 212b. The generated position information 213a and 213b are stored in information storage part 213. Image processing part 230 adjusts the position between the tomographic images Ga and Gb based on such position information 213a and 213b.
摘要翻译：图像形成部220形成眼底Ef（眼底图像）的表面的二维图像和眼底Ef的断层图像。在第一检查时间拍摄的眼底图像212a和眼底图像Ga以及在第二检查时间捕获的眼底图像212b和断层图像Gb被存储在图像存储部212中。位置信息生成部214生成位置指示眼底图像212a中的断层图像Ga的位置的信息213a和指示眼底图像212b中的断层图像Gb的位置的位置信息213b。所生成的位置信息213a和213b被存储在信息存储部分213中。图像处理部分230基于这样的位置信息213a和213b来调整断层图像Ga和Gb之间的位置。

10. 发明申请

US20070285619A1 Fundus Observation Device, An Ophthalmologic Image Processing Unit, An Ophthalmologic Image Processing Program, And An Ophthalmologic Image Processing Method 有权
标题翻译：眼底观察装置，眼科图像处理单元，眼科图像处理程序和眼科图像处理方法
公开(公告)号：US20070285619A1
公开(公告)日：2007-12-13
申请号：US11760314
申请日：2007-06-08
申请人： Hiroyuki Aoki , Takashu Fujimura , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
发明人： Hiroyuki Aoki , Takashu Fujimura , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
IPC分类号： A61B3/14
CPC分类号： A61B3/102 , G06T7/12 , G06T7/174 , G06T7/181 , G06T2207/10101 , G06T2207/30041
摘要： First image forming part forms a two-dimensional surface image of a fundus oculi of an eye based on optically obtained data. Second image forming part forms tomographic images of fundus oculi based on data obtained by optically scanning a region of the surface of fundus oculi corresponding to at least part of two-dimensional image. Accumulated image generating part generates an accumulated image by accumulating the formed tomographic images in a depth-wise direction. Extracting part extracts first vascular territory corresponding to a fundus oculi vessel from two-dimensional image formed by first image forming part, and also extracts second vascular territory corresponding to a fundus oculi vessel from accumulated image generated by accumulated image generating part. Specification part specifies a position of a vascular cross sectional region corresponding to a cross section of a fundus oculi vessel in the tomographic image based on extracted first vascular territory and extracted second vascular territory.
摘要翻译：第一图像形成部件基于光学获得的数据形成眼睛的眼底的二维表面图像。第二图像形成部分基于通过光学扫描与至少部分二维图像相对应的眼底表面的区域获得的数据来形成眼底的断层图像。累积图像生成部通过在深度方向累积形成的断层图像来生成累积图像。提取部分从由第一图像形成部分形成的二维图像中提取对应于眼底容器的第一血管区域，并且从累积图像生成部分生成的累积图像中提取与眼底容器对应的第二血管区域。规格部分基于提取的第一血管区域和提取的第二血管区域来指定与断层图像中的眼底血管的横截面对应的血管横截面区域的位置。

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