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    • 2. 发明申请
    • METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND
    • 用于生产光学活性萘基化合物的方法
    • US20150152082A1
    • 2015-06-04
    • US14240466
    • 2012-08-24
    • Koji MatsuyamaMasanori HatsudaMasahiko YoshinagaMitsuhiro YadaKoichi Tanimoto
    • Koji MatsuyamaMasanori HatsudaMasahiko YoshinagaMitsuhiro YadaKoichi Tanimoto
    • C07D401/04C07C255/03C07C25/06
    • C07D401/04C07B53/00C07C25/06C07C255/03
    • The present invention provides an industrially advantageous method for producing an optically active naphthalene compound useful as a therapeutic agent for dermatitis or the like. Specifically, the present invention provides a method for producing an optically active naphthalene compound [I], which comprises: a step of reacting a compound [a-1] and a compound [b-1] with each other in the presence of a base and a catalyst that is composed of a Pd compound and a tertiary phosphine ligand (step a); a step of asymmetrically hydrogenating a compound [c-1] in the presence of a hydrogen donor and a complex that is prepared from a ruthenium compound and a chiral ligand, or alternatively in the presence of an optically active oxazaborolidine compound (a CBS catalyst) and a boron hydride compound (step b); and a step of treating a compound [d-1] with a reducing agent (step c). (In the above formulae, Ra and Rb represent the same or different lower alkyl groups; and X1 represents a halogen atom.)
    • 本发明提供了用于制造用作皮炎等的治疗剂的光学活性萘化合物的工业上有利的方法。 具体而言,本发明提供了一种光学活性萘化合物[I]的制造方法,其特征在于,在碱的存在下,使化合物[a-1]和化合物[b-1] 和由Pd化合物和叔膦配体组成的催化剂(步骤a); 在氢供体和由钌化合物和手性配体制备的络合物的存在下,或者在光学活性的恶唑硼烷化合物(CBS催化剂)存在下,不对称地氢化化合物[c-1] 和硼氢化合物(步骤b); 和用还原剂处理化合物[d-1](步骤c)的步骤。 (上式中,Ra和Rb表示相同或不同的低级烷基,X1表示卤素原子。)
    • 10. 发明授权
    • Rotating electric machine with rotor cooling slots
    • 旋转电机带转子冷却槽
    • US08076805B2
    • 2011-12-13
    • US12057592
    • 2008-03-28
    • Yasuo KabataMasafumi FujitaMikio TakabatakeHitoshi KatayamaMikio KakiuchiKoji MatsuyamaYoshiyuki Shimoda
    • Yasuo KabataMasafumi FujitaMikio TakabatakeHitoshi KatayamaMikio KakiuchiKoji MatsuyamaYoshiyuki Shimoda
    • H02K9/00
    • H02K1/32H02K1/26H02K3/487
    • A rotor of a rotating electric machine includes a cylindrical rotor core, a plurality of coil slots provided on an outer periphery of the rotor core along a rotor axis direction, rotor coils disposed in the coil slots by laminating a plurality of field conductors through an insulation material, a rotor wedge disposed at an opening end portion of the coil slot so as to support the rotor coil, a coil ventilation duct formed in the coil slot so as to pass through the rotor coils, the rotor wedge and the insulation material, and sub-slots provided at bottom portions of the coil slots so as to be communicated with rotor core ends and the coil ventilation ducts. In such a rotor of a rotating electric machine, the coil slot, the sub-slots and the coil ventilation duct constitute a cooling gas channel for distributing a cooling gas to thereby cool the rotor coils. A depth in a diameter direction of each sub-slot from the rotor coil end to a nearest coil ventilation duct is larger than a depth of the sub-slot at a portion near a center of the rotor core.
    • 旋转电机的转子包括圆柱形转子芯,沿着转子轴线方向设置在转子芯的外周上的多个线圈槽,通过绝缘层叠多个场导体而设置在线圈槽中的转子线圈 材料,设置在所述线圈槽的开口端部的转子楔,以支撑所述转子线圈,形成在所述线圈槽中以便通过所述转子线圈,所述转子楔和绝缘材料的线圈通风管道,以及 设置在线圈槽的底部以与转子芯端部和线圈通风导管连通的副槽。 在旋转电机的转子中,线圈槽,副槽和线圈通风管构成用于分配冷却气体从而冷却转子线圈的冷却气体通道。 从转子线圈端到最近的线圈通风管的每个子槽的直径方向的深度大于在转子芯的中心附近的部分处的子槽的深度。