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1. 发明授权

US09317941B2 Method of image reconstruction for a filtered back projection in limited angle tomography 有权
标题翻译：用于有限角度层析成像中滤波反投影的图像重建方法
公开(公告)号：US09317941B2
公开(公告)日：2016-04-19
申请号：US14344230
申请日：2012-08-27
申请人： Tim Nielsen , Sebastian Hitziger , Michael Grass
发明人： Tim Nielsen , Sebastian Hitziger , Michael Grass
IPC分类号： G06K9/00 , G06T11/00 , A61B6/03
CPC分类号： G06T11/006 , A61B6/035 , G06T2210/41 , G06T2211/421 , G06T2211/436
摘要： The present invention is directed to a limited angle tomography in combination with a filtered back projection using a special filter operator X. The filter operator X used within the present invention makes it possible to perform region of interest reconstructions although delivering high quality reconstruction images as generated by high effort SART methods. The used filter operator is purely and solely mathematically determined and defined by the spatial geometry which is used for the limited angle tomography. Without having the need to perform several iterations, the present invention directly calculates a solution, i.e. reconstructed image, equivalent to known iteratively construction methods. Although, incomplete projection data p may only be used, the present invention provides for a high image quality.
摘要翻译：本发明涉及一种与使用特殊滤波器操作器X的滤波反投影相结合的有限角度断层摄影。本发明中使用的滤波器操作器X可以执行感兴趣的重建区域，尽管传送高质量的重建图像产生通过高效的SART方法。所使用的过滤器操作员纯粹且仅在数学上由用于有限角度层析成像的空间几何来确定和限定。在不需要进行多次迭代的情况下，本发明直接计算与已知的迭代构造方法相当的解，即重构图像。尽管可以仅使用不完全的投影数据p，但是本发明提供了高图像质量。

2. 发明授权

US07856079B2 Reconstruction method for computer tomography and computer tomograph 有权
标题翻译：计算机断层扫描和计算机断层扫描重建方法
公开(公告)号：US07856079B2
公开(公告)日：2010-12-21
申请号：US11719304
申请日：2005-11-07
申请人： Tim Nielsen , Michael Grass
发明人： Tim Nielsen , Michael Grass
IPC分类号： A61B6/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/424
摘要： It is an object of the invention to provide spiral computer tomography which has a high image quality. It relates to a reconstruction method for computer tomography of the heart, wherein the image is reconstructed from a data component of recordings of a partial detector path of a detector device and from a data component of recordings of a full detector path of the detector device, and to a computer tomograph having a beam source, a drive arrangement for driving the beam source in a spiral path around an object, a detector device for recording the radiation from the beam source which passes at least partially through the object, and a control device for reconstructing data components of a partial detector path and a full detector path.
摘要翻译：本发明的目的是提供具有高图像质量的螺旋计算机断层摄影。本发明涉及用于心脏计算机断层摄影的重建方法，其中根据检测器装置的部分检测器路径的记录的数据分量和检测器装置的完整检测器路径的记录的数据分量来重建图像，以及具有光束源的计算机断层摄影机，用于以围绕物体的螺旋路径驱动光束源的驱动装置，用于记录来自至少部分穿过物体的光束源的辐射的检测器装置，以及控制装置用于重构部分检测器路径和完整检测器路径的数据分量。

3. 发明申请

US20140348407A1 METHOD OF IMAGE RECONSTRUCTION FOR A FILTERED BACK PROJECTION IN LIMITED ANGLE TOMOGRAPHY 有权
标题翻译：用于有角度角度扫描的过滤背投影的图像重建方法
公开(公告)号：US20140348407A1
公开(公告)日：2014-11-27
申请号：US14344230
申请日：2012-08-27
申请人： Tim Nielsen , Sebastian Hitziger , Michael Grass
发明人： Tim Nielsen , Sebastian Hitziger , Michael Grass
IPC分类号： G06T11/00 , A61B6/03
CPC分类号： G06T11/006 , A61B6/035 , G06T2210/41 , G06T2211/421 , G06T2211/436
摘要： The present invention is directed to a limited angle tomography in combination with a filtered back projection using a special filter operator X. The filter operator X used within the present invention makes it possible to perform region of interest reconstructions although delivering high quality reconstruction images as generated by high effort SART methods. The used filter operator is purely and solely mathematically determined and defined by the spatial geometry which is used for the limited angle tomography. Without having the need to perform several iterations, the present invention directly calculates a solution, i.e. reconstructed image, equivalent to known iteratively construction methods. Although, incomplete projection data p may only be used, the present invention provides for a high image quality.
摘要翻译：本发明涉及一种与使用特殊滤波器操作器X的滤波反投影相结合的有限角度断层摄影。本发明中使用的滤波器操作器X可以执行感兴趣的重建区域，尽管传送高质量的重建图像产生通过高效的SART方法。所使用的过滤器操作员纯粹且仅在数学上由用于有限角度层析成像的空间几何来确定和限定。在不需要进行多次迭代的情况下，本发明直接计算与已知的迭代构造方法相当的解，即重构图像。尽管可以仅使用不完全的投影数据p，但是本发明提供了高图像质量。

4. 发明授权

US07630528B2 Motion compensation 有权
标题翻译：运动补偿
公开(公告)号：US07630528B2
公开(公告)日：2009-12-08
申请号：US10598421
申请日：2005-02-23
申请人： Thomas Kohler , Michael Grass , Tim Nielsen , Peter Koken
发明人： Thomas Kohler , Michael Grass , Tim Nielsen , Peter Koken
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T11/006 , G06T2211/412
摘要： Using only projection data in one temporal gating window around a certain target phase point may lead to motion artifacts such as blurred images. By using projection data corresponding to three temporal gating windows, which are slightly shifted with respect to each other but at least partially overlap, motion within the gating window may be estimated and, according to an exemplary embodiment of the present invention, this estimation may be used for improving the image quality. Advantageously, only the projection data inside the at least partially overlapping gating windows are used for reconstruction and motion compensation.
摘要翻译：在某个目标相位点周围的一个时间门控窗口中仅使用投影数据可能会导致运动伪影，如模糊图像。通过使用对应于相对于彼此略微偏移但至少部分重叠的三个时间门控窗口的投影数据，可以估计门控窗口内的运动，并且根据本发明的示例性实施例，该估计可以是用于提高图像质量。有利地，仅将至少部分重叠的门控窗口内的投影数据用于重建和运动补偿。

5. 发明授权

US07676018B2 Efficient iterative four-dimensional cardiac cone-beam CT reconstruction 有权
标题翻译：高效迭代四维心脏锥束CT重建
公开(公告)号：US07676018B2
公开(公告)日：2010-03-09
申请号：US12065615
申请日：2006-09-01
申请人： Michael Grass , Andy Ziegler , Tim Nielsen
发明人： Michael Grass , Andy Ziegler , Tim Nielsen
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/027 , A61B6/541 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： The increasing cone angle of current high-end and future CT systems leads to a decrease in image quality if approximate cone-beam reconstruction methods are used. According to an exemplary embodiment of the present invention, an iterative four-dimensional cardiac CT reconstruction is provided, in which phase volumes are selected from the four-dimensional data set, each having the same spatial volume at different phase points. Corresponding voxels inside these phase volumes are then forward projected onto the same projection. After calculation of a different projection, these voxels are updated. This may provide for an efficient implementation of an iterative four-dimensional cardiac cone-beam CT reconstruction.
摘要翻译：目前高端和未来CT系统锥角的增加导致使用近似锥束重建方法时图像质量下降。根据本发明的示例性实施例，提供了一种迭代的四维心脏CT重建，其中从四维数据集中选择相位体积，每个四维数据集在不同相位处具有相同的空间体积。然后将这些相位体积内的相应体素向前投影到相同的投影上。在计算了不同的投影之后，这些体素被更新。这可以提供迭代四维心脏锥束CT重建的有效实施。

6. 发明申请

US20080267480A1 Iterative Image Reconstruction of a Moving Object From Projection Data 审中-公开
标题翻译：投影数据中移动物体的迭代图像重建
公开(公告)号：US20080267480A1
公开(公告)日：2008-10-30
申请号：US12097544
申请日：2006-12-08
申请人： Tim Nielsen , Michael Grass , Andy Ziegler
发明人： Tim Nielsen , Michael Grass , Andy Ziegler
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/412 , G06T2211/424
摘要： Iterative methods for reconstructing an image sequence of a moving object based on projection data usually require a high computationally effort. According to embodiments of the present invention there is provided such a method wherein a first image representing the object at a first phase is used as an initial image for iteratively reconstructing a second image at a second phase. A first gating function is assigned to the first phase, a second gating function is assigned to the second phase. When executing a first iteration for reconstructing the second image only projection data corresponding to a non-overlapping part of the two gating functions are used. For executing further iterations the amount of projection data corresponding to the overlapping part of the two gating functions may be gradually increased. Therefore, for all further but the last iteration the computationally effort is significantly reduced. However, this low computationally expense has no negative impact on the quality of the finally reconstructed second image because the method benefits from the fact that the first image was used as the initial image for iteratively reconstructing the second image.
摘要翻译：基于投影数据重建移动物体的图像序列的迭代方法通常需要较高的计算量。根据本发明的实施例，提供了这样的方法，其中将表示第一阶段的对象的第一图像用作用于在第二阶段迭代重建第二图像的初始图像。第一门控功能被分配给第一阶段，第二门控功能被分配给第二阶段。当执行用于重构第二图像的第一次迭代时，仅使用与两个门控功能的非重叠部分相对应的投影数据。为了执行进一步的迭代，可以逐渐增加对应于两个门控功能的重叠部分的投影数据量。因此，对于所有进一步但最后的迭代，计算量的努力显着降低。然而，这种低的计算费用对最终重建的第二图像的质量没有负面影响，因为该方法受益于第一图像被用作用于迭代重建第二图像的初始图像的事实。

7. 发明申请

US20080267342A1 Efficient Iterative Four-Dimensional Cardiac Cone-Beam Ct Reconstruction 有权
标题翻译：高效迭代四维心脏锥束重建
公开(公告)号：US20080267342A1
公开(公告)日：2008-10-30
申请号：US12065615
申请日：2006-09-01
申请人： Michael Grass , Andy Ziegler , Tim Nielsen
发明人： Michael Grass , Andy Ziegler , Tim Nielsen
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/027 , A61B6/541 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： The increasing cone angle of current high-end and future CT systems leads to a decrease in image quality if approximate cone-beam reconstruction methods are used. According to an exemplary embodiment of the present invention, an iterative four-dimensional cardiac CT reconstruction is provided, in which phase volumes are selected from the four-dimensional data set, each having the same spatial volume at different phase points. Corresponding voxels inside these phase volumes are then forward projected onto the same projection. After calculation of a different projection, these voxels are updated. This may provide for an efficient implementation of an iterative four-dimensional cardiac cone-beam CT reconstruction.
摘要翻译：目前高端和未来CT系统锥角的增加导致使用近似锥束重建方法时图像质量下降。根据本发明的示例性实施例，提供了一种迭代的四维心脏CT重建，其中从四维数据集中选择相位体积，每个四维数据集在不同相位处具有相同的空间体积。然后将这些相位体积内的相应体素向前投影到相同的投影上。在计算了不同的投影之后，这些体素被更新。这可以提供迭代四维心脏锥束CT重建的有效实施。

8. 发明申请

US20090074133A1 Reconstruction Method for Computer Tomograph and Computer Tomograph 有权
标题翻译：计算机断层图和计算机图像重建方法
公开(公告)号：US20090074133A1
公开(公告)日：2009-03-19
申请号：US11719304
申请日：2005-11-07
申请人： Tim Nielsen , Michael Grass
发明人： Tim Nielsen , Michael Grass
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/424
摘要： It is an object of the invention to provide spiral computer tomography which has a high image quality. It relates to a reconstruction method for computer tomography of the heart, wherein the image is reconstructed from a data component of recordings of a partial detector path of a detector device and from a data component of recordings of a full detector path of the detector device, and to a computer tomograph having a beam source, a drive arrangement for driving the beam source in a spiral path around an object, a detector device for recording the radiation from the beam source which passes at least partially through the object, and a control device for reconstructing data components of a partial detector path and a full detector path.
摘要翻译：本发明的目的是提供具有高图像质量的螺旋计算机断层摄影。本发明涉及用于心脏计算机断层摄影的重建方法，其中根据检测器装置的部分检测器路径的记录的数据分量和检测器装置的完整检测器路径的记录的数据分量来重建图像，以及具有光束源的计算机断层摄影机，用于以围绕物体的螺旋路径驱动光束源的驱动装置，用于记录来自至少部分穿过物体的光束源的辐射的检测器装置，以及控制装置用于重构部分检测器路径和完整检测器路径的数据分量。

9. 发明申请

US20070183639A1 Motion compensation 有权
标题翻译：运动补偿
公开(公告)号：US20070183639A1
公开(公告)日：2007-08-09
申请号：US10598421
申请日：2005-02-23
申请人： Thomas Kohler , Michael Grass , Tim Nielsen , Peter Koken
发明人： Thomas Kohler , Michael Grass , Tim Nielsen , Peter Koken
IPC分类号： G06K9/00 , G06K9/40
CPC分类号： G06T11/006 , G06T2211/412
摘要： Using only projection data in one temporal gating window around a certain target phase point may lead to motion artifacts such as blurred images. By using projection data corresponding to three temporal gating windows, which are slightly shifted with respect to each other but at least partially overlap, motion within the gating window may be estimated and, according to an exemplary embodiment of the present invention, this estimation may be used for improving the image quality. Advantageously, only the projection data inside the at least partially overlapping gating windows are used for reconstruction and motion compensation.
摘要翻译：在某个目标相位点周围的一个时间门控窗口中仅使用投影数据可能会导致运动伪影，如模糊图像。通过使用对应于相对于彼此略微偏移但至少部分重叠的三个时间门控窗口的投影数据，可以估计门控窗口内的运动，并且根据本发明的示例性实施例，该估计可以是用于提高图像质量。有利地，仅将至少部分重叠的门控窗口内的投影数据用于重建和运动补偿。

10. 发明授权

US09848843B2 Dynamic perfusion imaging 有权
公开(公告)号：US09848843B2
公开(公告)日：2017-12-26
申请号：US14112047
申请日：2012-04-17
申请人： Michael Grass , Holger Schmitt
发明人： Michael Grass , Holger Schmitt
IPC分类号： A61B6/00
CPC分类号： A61B6/481 , A61B6/00 , A61B6/486 , A61B6/503 , A61B6/507 , A61B6/5217 , A61B6/542 , A61B6/545 , F04C2270/0421
摘要： A method includes scanning a region of interest, during a contrast agent based perfusion scan, at a predetermined temporal sampling rate during contrast agent uptake in the region of interest, and generating time frame data indicative of the scanned region of interest. The method further includes identifying a predetermined change in an amount of the contrast agent in the region of interest from the time frame data. The method further includes scanning the region of interest at a lower temporal sampling rate, which is lower than the temporal sampling rate during the contrast agent uptake, in response to identifying the predetermined change in the amount of the contrast agent in the region of interest.

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