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1. 发明申请

US20110166584A1 CLIP APPLIER AND METHODS OF USE 有权
公开(公告)号：US20110166584A1
公开(公告)日：2011-07-07
申请号：US12987792
申请日：2011-01-10
申请人： Thomas J. Palermo , William M. Belef , Michael T. Carley , Richard S. Ginn , Ronald J. Jabba , Anthony Pantages
发明人： Thomas J. Palermo , William M. Belef , Michael T. Carley , Richard S. Ginn , Ronald J. Jabba , Anthony Pantages
IPC分类号： A61B17/08 , A61B17/00
CPC分类号： A61B17/064 , A61B17/0057 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/1227 , A61B17/1285 , A61B2017/00637 , A61B2017/00672
摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.

2. 发明授权

US08926656B2 Clip applier and methods of use 有权
标题翻译：夹子施放器和使用方法
公开(公告)号：US08926656B2
公开(公告)日：2015-01-06
申请号：US12987792
申请日：2011-01-10
申请人： Thomas J Palermo , William M Belef , Michael T Carley , Richard S Ginn , Ronald J Jabba , Anthony Pantages
发明人： Thomas J Palermo , William M Belef , Michael T Carley , Richard S Ginn , Ronald J Jabba , Anthony Pantages
IPC分类号： A61B17/00 , A61B17/068 , A61B17/122 , A61B17/064 , A61B17/128
CPC分类号： A61B17/064 , A61B17/0057 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/1227 , A61B17/1285 , A61B2017/00637 , A61B2017/00672
摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.
摘要翻译：一种用于将闭合元件输送到形成在血管或其他体腔中的开口中的装置及其制造和使用方法。该装置构造成保持封闭元件，使得封闭元件基本上设置在该装置内。该装置还可以将封闭件基本上邻近开口附近的血管壁接合并定位。在封闭元件的展开过程中，该装置将闭合元件膨胀超过封闭元件的自然横截面，使得封闭元件在展开时构造成与大量的血管壁和/或组织接合。接合血管壁和/或组织，闭合元件进一步构造成返回到自然横截面，从而将所接合的血管壁和/或组织基本上闭合和/或密封，使得开口内止血增强。

3. 发明授权

US07867249B2 Clip applier and methods of use 有权
公开(公告)号：US07867249B2
公开(公告)日：2011-01-11
申请号：US10638115
申请日：2003-08-08
申请人： Thomas J Palermo , William M Belef , Michael T Carley , Richard S Ginn , Ronald J Jabba , Anthony Pantages
发明人： Thomas J Palermo , William M Belef , Michael T Carley , Richard S Ginn , Ronald J Jabba , Anthony Pantages
IPC分类号： A61B17/08
CPC分类号： A61B17/064 , A61B17/0057 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/1227 , A61B17/1285 , A61B2017/00637 , A61B2017/00672
摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.

4. 发明授权

US09579091B2 Closure system and methods of use 有权
标题翻译：封闭系统和使用方法
公开(公告)号：US09579091B2
公开(公告)日：2017-02-28
申请号：US11396731
申请日：2006-04-03
申请人： Richard S. Ginn , William N. Aldrich , W. Martin Belef , Steven N. Roe , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui , Janina Sagastegui
发明人： Richard S. Ginn , William N. Aldrich , W. Martin Belef , Steven N. Roe , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
IPC分类号： A61B17/08 , A61B17/00 , A61B17/064
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/0643 , A61B17/083 , A61B2017/00637 , A61B2017/00654 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641
摘要： A closure system and methods of use are provided for use in sealing an opening in a body tissue, such as a vascular puncture site. A method of closing the opening in the body tissue can be performed with the closure system having a closure clip. The method can include positioning the closure clip in a first closure clip position adjacent to the opening in the body tissue such that a plurality of spikes of the closure clip are inserted into the tissue at a location outward from a central axis of the opening. Subsequently, the closure clip can be positioned in a second closure clip position such that the plurality of spikes are pulled inward toward the central axis of the opening so as to pull the tissue between the opening and each of the spikes together and close the opening.
摘要翻译：提供封闭系统和使用方法用于密封诸如血管穿刺部位的身体组织中的开口。可以在具有闭合夹的封闭系统中执行关闭身体组织中的开口的方法。该方法可以包括将闭合夹定位在与身体组织中的开口相邻的第一闭合夹具位置中，使得闭合夹的多个尖峰在从开口的中心轴线向外的位置插入到组织中。随后，闭合夹可以被定位在第二闭合夹夹位置中，使得多个钉被向内朝向开口的中心轴线向内拉，以便将开口和每个钉之间的组织拉到一起并关闭开口。

5. 发明授权

US07828817B2 Apparatus and methods for delivering a closure device 有权
标题翻译：用于传送闭合装置的装置和方法
公开(公告)号：US07828817B2
公开(公告)日：2010-11-09
申请号：US11198811
申请日：2005-08-04
申请人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
发明人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
IPC分类号： A61B17/08
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/064 , A61B17/128 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641
摘要： An apparatus for delivering a clip to close an opening through tissue includes a sheath and a carrier assembly including a clip therein that is slidable on the sheath. An actuator assembly is connectable to the sheath, and telescoping actuator members extend from the handle that are connectable to the carrier assembly for advancing the carrier assembly along the sheath. An obturator on the actuator assembly includes splines that may be deployed beyond a distal end of the sheath, and expanded to a transverse expanded configuration for positioning the sheath before deploying the clip. The actuator members include cooperating detents that selectively release the actuator members as the carrier assembly reaches predetermined positions along the sheath for deploying the clip from the carrier assembly, and that collapse the splines to allow removal of the apparatus after deploying the clip.
摘要翻译：用于递送夹子以封闭通过组织的开口的装置包括护套和载体组件，其包括可在护套上滑动的夹子。致动器组件可连接到护套，并且可伸缩的致动器构件从手柄延伸，所述手柄可连接到托架组件，用于沿着护套推进托架组件。致动器组件上的密封件包括可以部署在鞘的远端之外的花键，并且在展开夹子之前扩展成横向扩展构型以定位护套。致动器构件包括配合的棘爪，当托架组件沿着护套到达预定位置时，选择性地释放致动器构件，用于将夹子从承载器组件展开，并且在使用夹子之后使花键折叠以允许移除装置。

6. 发明授权

US06942674B2 Apparatus and methods for delivering a closure device 有权
公开(公告)号：US06942674B2
公开(公告)日：2005-09-13
申请号：US10081723
申请日：2002-02-21
申请人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
发明人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
IPC分类号： A61B17/00 , A61B17/064 , A61B17/08 , A61B17/128 , A61B19/00 , A61B17/10
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/064 , A61B17/128 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641
摘要： An apparatus for delivering a clip to close an opening through tissue includes a sheath and a carrier assembly including a clip therein that is slidable on the sheath. An actuator assembly is connectable to the sheath, and telescoping actuator members extend from the handle that are connectable to the carrier assembly for advancing the carrier assembly along the sheath. An obturator on the actuator assembly includes splines that may be deployed beyond a distal end of the sheath, and expanded to a transverse expanded configuration for positioning the sheath before deploying the clip. The actuator members include cooperating detents that selectively release the actuator members as the carrier assembly reaches predetermined positions along the sheath for deploying the clip from the carrier assembly, and that collapse the splines to allow removal of the apparatus after deploying the clip.

7. 发明授权

US06749621B2 Sheath apparatus and methods for delivering a closure device 有权
公开(公告)号：US06749621B2
公开(公告)日：2004-06-15
申请号：US10081725
申请日：2002-02-21
申请人： Anthony Pantages , Ronald J. Jabba , Richard S. Ginn
发明人： Anthony Pantages , Ronald J. Jabba , Richard S. Ginn
IPC分类号： A61B1704
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/08 , A61B2017/00004 , A61B2017/00637 , A61B2017/00659 , A61B2017/00668 , A61B2017/00672 , A61B2017/0641
摘要： An apparatus for delivering a clip includes an introducer sheath including an outer surface extending between its proximal and distal ends. A clip is carried on the outer surface, e.g., on a carrier assembly that is slidable along the outer surface from the proximal end towards the distal end. A skin overlies the outer surface of the sheath and the carrier assembly that is separable from the outer surface as the carrier assembly is advanced from the proximal end towards the distal end of the sheath. During use, the distal end of the sheath is inserted into an opening through tissue, e.g., into a puncture communicating with a blood vessel. The carrier assembly is advanced towards the distal end of the sheath, causing the skin to separate from the outer surface of the elongate member, and the clip is deployed from the carrier to seal the opening.

8. 发明授权

US06695867B2 Plunger apparatus and methods for delivering a closure device 有权
标题翻译：柱塞装置和用于传送闭合装置的方法
公开(公告)号：US06695867B2
公开(公告)日：2004-02-24
申请号：US10081717
申请日：2002-02-21
申请人： Richard S. Ginn , Anthony Pantages
发明人： Richard S. Ginn , Anthony Pantages
IPC分类号： A61B1708
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/08 , A61B2017/00004 , A61B2017/00637 , A61B2017/00659 , A61B2017/00668 , A61B2017/00672 , A61B2017/0641
摘要： An apparatus for delivering a clip includes an introducer sheath including an outer surface extending between its proximal and distal ends, and a hub on the proximal end that includes spacer elements spaced away from the outer surface. An annular clip includes a plurality of tines extending from its distal end and its proximal end is held away from the outer surface of the sheath by the spacer elements. A handle assembly is attached to the hub that includes an actuator member slidable between the spacer elements and the outer surface of the sheath. The actuator member includes radial protrusions for coupling with the clip, whereby distal movement of the actuator member advances the clip towards the distal end of the sheath. Optionally, a skin overlies the outer surface of the sheath and the clip that is separable from the outer surface as the clip is advanced.
摘要翻译：用于递送夹子的装置包括导引鞘，其包括在其近端和远端之间延伸的外表面，以及在近端上的毂，其包括与外表面间隔开的间隔元件。环形夹具包括从其远端延伸的多个尖齿，并且其近端通过间隔元件远离护套的外表面。手柄组件附接到毂，其包括可在间隔元件和护套的外表面之间滑动的致动器构件。致动器构件包括用于与夹子联接的径向突起，由此致动器构件的远端运动使夹子朝向护套的远端前进。任选地，当夹子前进时，皮肤覆盖护套的外表面和夹子，该夹子可与外表面分离。

9. 发明授权

US08007512B2 Plunger apparatus and methods for delivering a closure device 有权
标题翻译：柱塞装置和用于传送闭合装置的方法
公开(公告)号：US08007512B2
公开(公告)日：2011-08-30
申请号：US10682459
申请日：2003-10-08
申请人： Richard S. Ginn , Anthony Pantages
发明人： Richard S. Ginn , Anthony Pantages
IPC分类号： A61B17/08 , A61B17/10 , A61D1/00
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/08 , A61B2017/00004 , A61B2017/00637 , A61B2017/00659 , A61B2017/00668 , A61B2017/00672 , A61B2017/0641
摘要： An apparatus for delivering a clip includes an introducer sheath including an outer surface extending between its proximal and distal ends, and a hub on the proximal end that includes spacer elements spaced away from the outer surface. An annular clip includes a plurality of tines extending from its distal end and its proximal end is held away from the outer surface of the sheath by the spacer elements. A handle assembly is attached to the hub that includes an actuator member slidable between the spacer elements and the outer surface of the sheath. The actuator member includes radial protrusions for coupling with the clip, whereby distal movement of the actuator member advances the clip towards the distal end of the sheath. Optionally, a skin overlies the outer surface of the sheath and the clip that is separable from the outer surface as the clip is advanced.
摘要翻译：用于递送夹子的装置包括导引鞘，其包括在其近端和远端之间延伸的外表面，以及在近端上的毂，其包括与外表面间隔开的间隔元件。环形夹具包括从其远端延伸的多个尖齿，并且其近端通过间隔元件远离护套的外表面。手柄组件附接到毂，其包括可在间隔元件和护套的外表面之间滑动的致动器构件。致动器构件包括用于与夹子联接的径向突起，由此致动器构件的远端运动使夹子朝向护套的远端前进。任选地，当夹子前进时，皮肤覆盖护套的外表面和夹子，该夹子可与外表面分离。

10. 发明申请

US20070032798A1 Vascular suturing device with needle capture 有权
标题翻译：带针捕获的血管缝合装置
公开(公告)号：US20070032798A1
公开(公告)日：2007-02-08
申请号：US11199496
申请日：2005-08-08
申请人： Anthony Pantages , Brian Ellingwood , Erik Walberg
发明人： Anthony Pantages , Brian Ellingwood , Erik Walberg
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/06004 , A61B2017/00637 , A61B2017/00663 , A61B2017/0454 , A61B2017/0464 , A61B2017/06009
摘要： A surgical device of suturing vascular vessels is described, as well as methods for suturing tissue employing the surgical device. The device includes at least one needle advanceable through tissue and into a needle capture element within a distal end of the surgical device to draw lengths of suture material which can then be used to close various puncture wounds, particularly in vascular tissue.
摘要翻译：描述缝合血管的手术装置，以及使用手术装置缝合组织的方法。该装置包括至少一个能够穿过组织前进的针并且进入外科手术装置的远端内的针捕获元件，以抽取缝合材料的长度，然后缝合材料可用于封闭各种穿刺伤口，特别是在血管组织中。

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