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1. 发明授权

US08354426B2 Naphthyridine derivative monohydrate and method for producing the same 失效
标题翻译：萘啶衍生物一水合物及其制备方法
公开(公告)号：US08354426B2
公开(公告)日：2013-01-15
申请号：US12744633
申请日：2008-11-25
申请人： Taro Kiyoto , Masahiro Takebayashi , Yasutaka Baba , Muneo Syoji , Toshiya Noguchi , Fumihito Ushiyama , Hiroki Urabe , Hiromasa Horikiri
发明人： Taro Kiyoto , Masahiro Takebayashi , Yasutaka Baba , Muneo Syoji , Toshiya Noguchi , Fumihito Ushiyama , Hiroki Urabe , Hiromasa Horikiri
IPC分类号： A61K31/436 , A61K31/4353 , C07D471/04
CPC分类号： C07D519/00 , C07D309/40 , C07D491/04
摘要： Disclosed is 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate, which has strong antibacterial activity. The compound is highly safe and useful as an original drug for pharmaceutical preparations. Also disclosed is a method which is useful for producing 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate.
摘要翻译：公开了1-（2-（4 - （（2,3-二氢（1,4）二氧杂环己烯（2,3-c）吡啶-7-基甲基）氨基）哌啶-1-基）乙基） -1,5-二氮杂萘-2（1H） - 酮一水合物，具有很强的抗菌活性。该化合物作为药物制剂的原始药物是高度安全和有用的。还公开了可用于制备1-（2-（4 - （（2,3-二氢（1,4）二恶英（2,3-c）吡啶-7-基甲基）氨基）吡啶-2-基）乙基）-7-氟-1,5-二氮杂萘-2（1H） - 酮一水合物。

2. 发明申请

US20100249417A1 NOVEL NAPHTHYRIDINE DERIVATIVE MONOHYDRATE AND METHOD FOR PRODUCING THE SAME 失效
标题翻译：新型萘啶衍生物单硬脂酸酯及其制造方法
公开(公告)号：US20100249417A1
公开(公告)日：2010-09-30
申请号：US12744633
申请日：2008-11-25
申请人： Taro Kiyoto , Masahiro Takebayashi , Yasutaka Baba , Muneo Syoji , Toshiya Noguchi , Fumihito Ushiyama , Hiroki Urabe , Hiromasa Horikiri
发明人： Taro Kiyoto , Masahiro Takebayashi , Yasutaka Baba , Muneo Syoji , Toshiya Noguchi , Fumihito Ushiyama , Hiroki Urabe , Hiromasa Horikiri
IPC分类号： C07D491/056 , C07D315/00
CPC分类号： C07D519/00 , C07D309/40 , C07D491/04
摘要： Disclosed is 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate, which has strong antibacterial activity. The compound is highly safe and useful as an original drug for pharmaceutical preparations. Also disclosed is a method which is useful for producing 1-(2-(4-((2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)amino)piperidin-1-yl)ethyl)-7-fluoro-1,5-naphthyridin-2(1H)-one monohydrate.
摘要翻译：公开了1-（2-（4 - （（2,3-二氢（1,4）二氧杂环己烯（2,3-c）吡啶-7-基甲基）氨基）哌啶-1-基）乙基） -1,5-二氮杂萘-2（1H） - 酮一水合物，具有很强的抗菌活性。该化合物作为药物制剂的原始药物是高度安全和有用的。还公开了可用于制备1-（2-（4 - （（2,3-二氢（1,4）二恶英（2,3-c）吡啶-7-基甲基）氨基）吡啶-2-基）乙基）-7-氟-1,5-二氮杂萘-2（1H） - 酮一水合物。

3. 发明授权

US08017789B2 Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-OXO-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl]methoxy]phenyl]proprionate ester and intermediate for the process 有权
标题翻译：制备3- [5- [4-（环戊氧基）-2-羟基苯甲酰基] -2 - [（3-氧代-2-取代-2,3-二氢-1,2-苯并异恶唑-6-基）甲氧基 ]苯基]丙酸酯和该方法的中间体
公开(公告)号：US08017789B2
公开(公告)日：2011-09-13
申请号：US12280098
申请日：2007-02-19
申请人： Kenji Yonezawa , Tamotsu Takamatsu , Naokatu Aoki , Tomohiro Hashimoto , Masahiro Takebayashi , Yoshiaki Suzuki , Yuji Oonishi
发明人： Kenji Yonezawa , Tamotsu Takamatsu , Naokatu Aoki , Tomohiro Hashimoto , Masahiro Takebayashi , Yoshiaki Suzuki , Yuji Oonishi
IPC分类号： C07D261/20 , C07D311/02 , C07C69/612
CPC分类号： C07D261/20 , C07C67/03 , C07C67/303 , C07C69/738 , C07C2601/08 , C07D311/14
摘要： A preparation method using as an intermediate 6-(halomethyl)-1,2-benzisoxazol-3(2H)-one derivative represented by general formula wherein R5 is a methyl group that is substituted with one or more optionally substituted phenyl groups, or an optionally substituted oxygen-containing heterocyclic group; X represents a halogen atom, can be used as a method for safely and easily preparing 3-{5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-benzisoxazol-6-yl)methoxy]phenyl}propionic acid, which is useful as an antirheumatic agent, with a high yield.
摘要翻译：另外，作为中间体6-（卤代甲基）-1,2-苯并异恶唑-3（2H） - 酮衍生物的制备方法，其中R5是被一个或多个任意取代的苯基取代的甲基，或任选取代的含氧杂环基; X表示卤素原子，可用作安全且容易地制备3- {5- [4-（环戊氧基）-2-羟基苯甲酰基] -2 - [（3-羟基-1,2-苯并异恶唑-6-基）吡啶-2-基）甲氧基]苯基}丙酸，其可用作抗风湿剂，产率高。

4. 发明授权

US06179593B2 Displacement fluid machine 失效
标题翻译：排液机
公开(公告)号：US06179593B2
公开(公告)日：2001-01-30
申请号：US09044169
申请日：1998-03-19
申请人： Shunichi Mitsuya , Hirokatsu Kohsokabe , Masahiro Takebayashi , Koichi Inaba , Hiroaki Hata , Kenji Tojo
发明人： Shunichi Mitsuya , Hirokatsu Kohsokabe , Masahiro Takebayashi , Koichi Inaba , Hiroaki Hata , Kenji Tojo
IPC分类号： F01C102
CPC分类号： F04C18/04
摘要： Side wall surface of an orbiting piston and inner wall surface of a cylinder define therebetween a plurality of working chambers, a space for compressing (discharging) a working fluid is defined between spaces for sucking thereinto the working fluid among the working chambers in any operating condition, and one of end plates, between which the orbiting piston is axially interposed, is formed with suction ports or discharge ports while the other of end plates, opposing the end plate formed with the suction or discharge ports, is formed with holes, whereby it is possible to provide a highly efficient and reliable displacement fluid machine which can stabilize pressure balance in the working chambers, and which can greatly reduce fluid loss during discharge stroke.
摘要翻译：旋转活塞的侧壁表面和气缸的内壁表面限定了多个工作室，用于压缩（排出）工作流体的空间被限定在用于在任何操作条件下吸入工作室中的工作流体的空间之间并且其中轴向插入绕动活塞的端板之一形成有吸入口或排出口，而与形成有吸入口或排出口的端板相对的另一个端板形成有孔，由此其可以提供高效可靠的位移流体机械，其可以稳定工作室中的压力平衡，并且可以大大减少排放冲程期间的流体损失。

5. 发明授权

US5087170A Rotary compressor 失效
标题翻译：旋转压缩机
公开(公告)号：US5087170A
公开(公告)日：1992-02-11
申请号：US463556
申请日：1990-01-11
申请人： Hirokatu Kousokabe , Hiroshi Iwata , Masahiro Takebayashi
发明人： Hirokatu Kousokabe , Hiroshi Iwata , Masahiro Takebayashi
IPC分类号： F04C29/02 , F25B31/00
CPC分类号： F04C29/025 , F04C29/026 , F25B31/002 , Y10S417/902
摘要： A rotary compressor of the invention comprises an oil separating portion and an oil collecting portion located adjacent one end of a rotary shaft closely to a motor. An oil is separated through the oil separating portion and collected in the oil collecting portion in which the one end of the rotary shaft is submerged to lubricate a third bearing. The oil separating portion serves to separate oil mist which flows with gas flow. The one end of the rotary shaft is submerged in the oil as collected in the oil collecting portion under the influence of gravity to lubricate the bearing. This arrangement provides stable lubrication of the one end of the rotary shaft. The bearing is, thus, highly reliable while the rotary compressor is running at any speeds. Also, vibrations of the shaft can substantially be reduced particularly when the rotary compressor runs at a high speed.
摘要翻译：本发明的旋转压缩机包括油分离部分和靠近旋转轴的一端靠近马达的油收集部分。油通过油分离部分分离并收集在油回收部分中，旋转轴的一端被浸没在其中以润滑第三轴承。油分离部分用于分离与气流一起流动的油雾。旋转轴的一端在重力的作用下被收集在油收集部分中的油中，以润滑轴承。这种布置提供了旋转轴的一端的稳定的润滑。因此，在旋转式压缩机以任何速度运行的情况下，轴承是高度可靠的。此外，特别是当旋转式压缩机高速运转时，轴的振动也能够大幅降低。

6. 发明授权

US06406279B2 Displacement type fluid machine 失效
标题翻译：排量式流体机
公开(公告)号：US06406279B2
公开(公告)日：2002-06-18
申请号：US09808994
申请日：2001-03-16
申请人： Hirokatsu Kohsokabe , Masahiro Takebayashi , Shunichi Mitsuya , Hiroaki Hata , Yasuhiro Ohshima , Kenji Tojo
发明人： Hirokatsu Kohsokabe , Masahiro Takebayashi , Shunichi Mitsuya , Hiroaki Hata , Yasuhiro Ohshima , Kenji Tojo
IPC分类号： F01C102
CPC分类号： F04C18/04 , F01C21/106 , F04C27/001 , F04C2230/602 , F04C2240/30
摘要： A displacement type fluid machine has a sliding contact portion between a cylinder 4 and a displacer 5 made into a predetermined section, and the cylinder and the displacer so contoured that when they are made concentric, the normal distance in the sliding contact section between the cylinder contour and the displacer contour may be smaller than that of the remaining section, thereby to decrease the radial gap to lower the internal leakage of the working fluid and to improve the performance and the reliability.
摘要翻译：位移型流体机械在气缸4和制成预定部分的置换器5之间具有滑动接触部分，并且气缸和置换器具有如此轮廓，使得当它们同心时，气缸之间的滑动接触部分的正常距离轮廓和置换器轮廓可以小于剩余部分轮廓，从而减小径向间隙以降低工作流体的内部泄漏并提高性能和可靠性。

7. 发明授权

US6152714A Displacement type fluid machine having rotation suppression of an orbiting displacer 失效
标题翻译：具有旋转置换器的旋转抑制的位移式流体机械
公开(公告)号：US6152714A
公开(公告)日：2000-11-28
申请号：US932921
申请日：1997-09-18
申请人： Shunichi Mitsuya , Hirokatsu Kohsokabe , Masahiro Takebayashi , Koichi Inaba , Hiroaki Hata , Kenji Tojo
发明人： Shunichi Mitsuya , Hirokatsu Kohsokabe , Masahiro Takebayashi , Koichi Inaba , Hiroaki Hata , Kenji Tojo
IPC分类号： F01C1/04 , F01C17/06 , F04C23/00 , F04C29/00 , F01C21/04
CPC分类号： F04C23/008 , F01C1/04 , F01C17/066
摘要： A conventional displacement type fluid machine involves a problem that a mechanical friction loss and leakage in sliding portions are large, so that its reliability and performance are poor, and therefore it has not yet been put into practical use. In a displacement type fluid machine, a displacer makes an orbital motion within a cylinder to draw and discharge a working fluid. An compression element includes the displacer of a specified configuration, and the cylinder engaged with this displacer, and a connecting member (rotation prevention member), which abuts against the displacer and the cylinder, is provided inwardly of compression working chambers. With this construction, a rotating moment acting on the displacer can be completely avoided, thereby achieving the high efficiency and the high reliability.
摘要翻译：常规的排量型流体机械存在机械摩擦损失和滑动部分的泄漏大的问题，其可靠性和性能差，因此尚未投入实际应用。在位移式流体机器中，置换器在气缸内进行轨道运动以吸引和排出工作流体。压缩元件包括具有特定构造的置换器，并且与该置换器接合的气缸和抵靠置换器和气缸的连接构件（防旋转构件）设置在压缩工作室的内部。通过这种结构，可以完全避免作用在置换器上的旋转力矩，从而实现高效率和高可靠性。

8. 发明授权

US5938417A Scroll type fluid machine having wraps formed of circular arcs 失效
标题翻译：滚动式流体机器由圆弧形成
公开(公告)号：US5938417A
公开(公告)日：1999-08-17
申请号：US766468
申请日：1996-12-12
申请人： Kunihiko Takao , Hirokatsu Kohsokabe , Masahiro Takebayashi , Isao Hayase , Kenichi Oshima
发明人： Kunihiko Takao , Hirokatsu Kohsokabe , Masahiro Takebayashi , Isao Hayase , Kenichi Oshima
IPC分类号： F04C18/02 , F01C1/04
CPC分类号： F04C18/0246 , F04C18/0269
摘要： The present invention enables a scroll fluid machine to have a maximum design volume ratio without increasing an outside dimension of scrolls and allows the basic spiral curve of the scroll to be configured with simple curves. The basic spiral curve of a scroll wrap comprises a group of concentric semicircles, a group of circular arcs having a center different from that of the group of semicircles, and a group of straight lines or curves connecting the group of semicircles and the group of circular arcs together, and a diameter of the outer-most circumferential semicircle of a fixed scroll member is twice as large as radius of the outer-most circumferential circular arc of an orbiting scroll member. In addition, an outer diameter of an end plate of an orbiting scroll is equal to an outer diameter of the outer-most circumferential wrap of the scroll.
摘要翻译：本发明使得涡旋流体机器具有最大的设计体积比，而不增加涡卷的外部尺寸，并允许涡卷的基本螺旋曲线被配置成简单的曲线。涡卷的基本螺旋曲线包括一组同心半圆，一组具有与半圆组不同的中心的圆弧，以及一组连接半组的直线或曲线和圆形组弧形，并且固定涡旋构件的最外圆周半径的直径是绕动涡旋构件的最外周圆弧的半径的两倍。此外，绕动涡旋件的端板的外径等于涡卷的最外圆周包裹物的外径。

9. 发明授权

US06769888B2 Scroll compressor having a valved back pressure chamber and a bypass for overcompression 有权
标题翻译：涡旋压缩机具有带阀的背压室和用于过压的旁路
公开(公告)号：US06769888B2
公开(公告)日：2004-08-03
申请号：US10419232
申请日：2003-04-21
申请人： Isamu Tsubono , Masahiro Takebayashi , Isao Hayase , Koichi Inaba , Koichi Sekiguchi , Kenichi Oshima , Atsushi Shimada , Takehiro Akizawa
发明人： Isamu Tsubono , Masahiro Takebayashi , Isao Hayase , Koichi Inaba , Koichi Sekiguchi , Kenichi Oshima , Atsushi Shimada , Takehiro Akizawa
IPC分类号： F04C1804
CPC分类号： F04C28/16 , F04C18/0215 , F04C23/008 , F04C27/005 , Y10T137/7796
摘要： There is provided a scroll compressor having high overall adiabatic efficiency and reliability in a wide pressure operating range. A backside excess-suction-pressure region is provided such that pressure higher than suction pressure by a constant value is applied to a backside of scroll members to produce an attractive force to attract both scroll members. A control bypass is also provided for communicating compression chambers with a discharge system only when pressure in the compression chambers is high.
摘要翻译：提供了一种在广泛的压力操作范围内具有高整体绝热效率和可靠性的涡旋压缩机。设置背侧过剩吸入压力区域，使得高于吸入压力的压力恒定值的压力施加到涡旋件的背面以产生吸引两个涡旋件的吸引力。还提供控制旁路，用于仅在压缩室中的压力高时才将压缩室与排放系统连通。

10. 发明授权

US06494696B2 Scroll compressor 失效
标题翻译：涡旋压缩机
公开(公告)号：US06494696B2
公开(公告)日：2002-12-17
申请号：US09853587
申请日：2001-05-14
申请人： Toshiyuki Terai , Isao Hayase , Masahiro Takebayashi , Isamu Tsubono , Masaki Koyama , Koichi Sekiguchi
发明人： Toshiyuki Terai , Isao Hayase , Masahiro Takebayashi , Isamu Tsubono , Masaki Koyama , Koichi Sekiguchi
IPC分类号： F01C102
CPC分类号： F04C29/028
摘要： A scroll compressor comprising: a vessel; a compressing mechanism provided within said vessel, the compressing mechanism comprising an orbiting scroll and a non-orbiting scroll each having a spiral wrap formed in a base plate and an Oldham ring for preventing the orbiting scroll from rotating around its axis; an oil reservoir provided within a vessel; a crankshaft for transmitting a power for compressing a working fluid; and a frame on which a main bearing for supporting the crankshaft is provided, wherein the crankshaft is provided with oil supply passages for communicating a vicinity of an orbiting bearing and a vicinity of the main bearing, and openings of the oil supply passages in the vicinity of the orbiting bearing and in the vicinity of the main bearing are positioned so that a pressure of an oil film in the orbiting bearing opening generated during an operation of the compressor is higher than a pressure of an oil film in the-main bearing opening generated during an operation of the compressor.
摘要翻译：一种涡旋式压缩机，包括：容器; 设置在所述容器内的压缩机构，所述压缩机构包括绕动涡旋盘和非绕动涡旋盘，每个涡旋盘具有形成在基板中的螺旋涡卷和用于防止绕动涡旋件围绕其轴旋转的十字形环; 设在船只内的油库; 用于传送用于压缩工作流体的动力的曲轴; 在该框架上设置有用于支撑曲轴的主轴承，其中曲轴设有用于连通绕轴承附近和主轴承附近的供油通道以及附近的供油通道的开口的位置使得在压缩机的操作期间产生的绕动轴承开口中的油膜的压力高于主轴承开口中的油膜的压力，在压缩机的操作期间。

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