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1. 发明申请

US20070190021A1 Poly(diallylamine)-based bile acid sequestrants 审中-公开
标题翻译：聚（二烯丙基胺）为基础的胆汁酸多价螯合剂
公开(公告)号：US20070190021A1
公开(公告)日：2007-08-16
申请号：US11498309
申请日：2006-08-01
申请人： Stephen Holmes-Farley , Pradeep Dhal , John Petersen
发明人： Stephen Holmes-Farley , Pradeep Dhal , John Petersen
IPC分类号： A61K31/787
CPC分类号： B82Y5/00 , A61K31/785 , A61K31/787 , A61K31/795 , A61K47/6949 , C08G61/12 , Y10S514/824
摘要： The present invention relates to a method for removing bile acids from a patient and certain polymers of use in the method. The method comprises the step of administering to the patient a therapeutically effective amount of a polymer composition which includes a a poly(diallylamine)polymer which is substituted with hydrophobic groups. The hydrophobic groups can be a substituted or unsubstituted, straight chain or branched C3-C24-alkyl group, an aralkyl group or an aryl group.
摘要翻译：本发明涉及一种从患者中除去胆汁酸的方法和本方法中使用的某些聚合物。该方法包括向患者施用治疗有效量的聚合物组合物的步骤，该聚合物组合物包括被疏水基团取代的聚（二烯丙基胺）聚合物。疏水基团可以是取代或未取代的直链或支链C 3 -C 24 - 烷基，芳烷基或芳基。

2. 发明授权

US09037739B2 Method and system for sharing different web components between different web sites in a portal framework 有权
公开(公告)号：US09037739B2
公开(公告)日：2015-05-19
申请号：US12762087
申请日：2010-04-16
申请人： Dean Moses , Ed Anuff , Fergus Griffin , Jean Tessier , Hans Akesson , John Petersen , Tom Belunis , Edith Harbaugh , Noah Guyot , Dave MacLeod , Amy Phillips , Ethan Vonderweid
发明人： Dean Moses , Ed Anuff , Fergus Griffin , Jean Tessier , Hans Akesson , John Petersen , Tom Belunis , Edith Harbaugh , Noah Guyot , Dave MacLeod , Amy Phillips , Ethan Vonderweid
IPC分类号： G06F15/16 , H04L29/08 , G06F17/30 , G06Q10/10 , H04L29/06 , H04L12/24
CPC分类号： H04L67/1095 , G06F17/2247 , G06F17/30867 , G06F17/3089 , G06F17/30893 , G06Q10/10 , H04L29/06 , H04L41/22 , H04L41/28 , H04L63/105 , H04L67/10 , H04L67/1097 , H04L67/2838 , H04L67/2861 , H04L67/306 , H04L69/329
摘要： The sharing of objects may be executed by performing various share type administrations. Objects may be shared directly to a site or may be made available indirectly for reuse by a site. The objects shared and made available for reuse may be added to the site to which they are shared and made available for reuse. References to the objects shared and made available for reuse are stored in repositories in response to, and in accordance with, the share type administration performed. The storage of the references to objects is based on privileges associated with at least one of a repository, a site and a user. Objects made available for reuse by, and shared to, a site may be made unavailable for reuse by, and unshared to, the site through the execution of a share type administration.

3. 发明申请

US20120303765A1 SYSTEM USING CONTENT GENERATOR FOR DYNAMICALLY REGENERATING ONE OR MORE FRAGMENTS OF WEB PAGE BASED ON NOTIFICATION OF CONTENT CHANGE 有权
标题翻译：使用内容发生器的系统可以根据内容变更通知动态地再现一个或多个网页的页面
公开(公告)号：US20120303765A1
公开(公告)日：2012-11-29
申请号：US13566041
申请日：2012-08-03
申请人： N. Isaac Rajkumar , Mark McCalister , Expeditus Bolanus , Peter Hale , Mark Martin , Richard Nemec , Puhong You , Daun DeFrance , Ching-Fu Chang , Priya Reddy , Ladislav Kis , Robert L. Patterson , Tony Zgarba , Jeffrey M. Collins , Michael C. Tulkoff , Miles Chaston , Dean Moses , John Petersen , Ian Stahl , Lara Long
发明人： N. Isaac Rajkumar , Mark McCalister , Expeditus Bolanus , Peter Hale , Mark Martin , Richard Nemec , Puhong You , Daun DeFrance , Ching-Fu Chang , Priya Reddy , Ladislav Kis , Robert L. Patterson , Tony Zgarba , Jeffrey M. Collins , Michael C. Tulkoff , Miles Chaston , Dean Moses , John Petersen , Ian Stahl , Lara Long
IPC分类号： G06F15/16
CPC分类号： H04L67/2842 , G06F17/30769 , G06F17/30861 , G06F17/30893 , G06F17/30902 , H04L29/0809 , H04L67/02 , H04L67/2838 , H04L67/42
摘要： Disclosed herein are embodiments of a system and method for the provisioning of dynamically generated content. One embodiment can interface a content delivery system and a content management system at the fragment level. Depending upon how a page is organized, a fragment may refer to a block within the page, a portion of the page, or a content item presented on the page. When a content item is updated and published onto the content management system, one embodiment of the invention can operate to track dependencies of managed pages and invalidate/validate fragment(s) affected by the change(s) accordingly. The updated fragment(s) may then be dynamically assembled on-the-fly or on-demand. The updated fragment(s) may or may not be cached. In this way, changes made to a piece of content can be reflected in all pages which utilize this content almost simultaneously with the changes to the content itself.
摘要翻译：这里公开了用于提供动态生成的内容的系统和方法的实施例。一个实施例可以在片段级与内容传送系统和内容管理系统进行接口。根据页面的组织方式，片段可以引用页面中的块，页面的一部分或页面上呈现的内容项。当内容项目被更新并发布到内容管理系统上时，本发明的一个实施例可以操作以跟踪被管理页面的依赖性，并相应地使由变化影响的片段无效/验证。然后，可以动态或按需地动态地组合更新的片段。更新的片段可能被缓存或可能不被缓存。这样，对内容本身进行的更改几乎可以同时反映在所有使用此内容的页面中。

4. 发明授权

US07860820B1 System using content generator for dynamically regenerating one or more fragments of web page based on notification of content change 有权
标题翻译：使用内容生成器的系统基于内容更改的通知来动态地再现网页的一个或多个片段
公开(公告)号：US07860820B1
公开(公告)日：2010-12-28
申请号：US11444020
申请日：2006-05-31
申请人： N. Isaac Rajkumar , Mark McCalister , Expeditus Bolanos , Peter Hale , Mark Martin , Richard Nemec , Puhong You , Daun DeFrance , Ching-Fu Chang , Priya Reddy , Ladislav Kis , Robert L. Patterson , Tony Zgarba , Jeffrey M. Collins , Michael C. Tulkoff , Miles Chaston , Dean Moses , John Petersen , Ian Stahl , Lara Long
发明人： N. Isaac Rajkumar , Mark McCalister , Expeditus Bolanos , Peter Hale , Mark Martin , Richard Nemec , Puhong You , Daun DeFrance , Ching-Fu Chang , Priya Reddy , Ladislav Kis , Robert L. Patterson , Tony Zgarba , Jeffrey M. Collins , Michael C. Tulkoff , Miles Chaston , Dean Moses , John Petersen , Ian Stahl , Lara Long
IPC分类号： G06F7/00
CPC分类号： H04L67/2842 , G06F17/30769 , G06F17/30861 , G06F17/30893 , G06F17/30902 , H04L29/0809 , H04L67/02 , H04L67/2838 , H04L67/42
摘要： Disclosed herein are embodiments of a system and method for the provisioning of dynamically generated content. One embodiment can interface a content delivery system and a content management system at the fragment level. Depending upon how a page is organized, a fragment may refer to a block within the page, a portion of the page, or a content item presented on the page. When a content item is updated and published onto the content management system, one embodiment of the invention can operate to track dependencies of managed pages and invalidate/validate fragment(s) affected by the change(s) accordingly. The updated fragment(s) may then be dynamically assembled on-the-fly or on-demand. The updated fragment(s) may or may not be cached. In this way, changes made to a piece of content can be reflected in all pages which utilize this content almost simultaneously with the changes to the content itself.
摘要翻译：这里公开了用于提供动态生成的内容的系统和方法的实施例。一个实施例可以在片段级与内容传送系统和内容管理系统进行接口。根据页面的组织方式，片段可以引用页面中的块，页面的一部分或页面上呈现的内容项。当内容项目被更新并发布到内容管理系统上时，本发明的一个实施例可以操作以跟踪被管理页面的依赖性，并相应地使由变化影响的片段无效/验证。然后，可以动态或按需地动态地组合更新的片段。更新的片段可能被缓存或可能不被缓存。这样，对内容本身进行的更改几乎可以同时反映在所有使用此内容的页面中。

5. 发明申请

US20100274812A1 Method and System for Sharing Different Web Components Between Different Web Sites in a Portal Framework 有权
标题翻译：在门户框架中不同Web站点之间共享不同Web组件的方法和系统
公开(公告)号：US20100274812A1
公开(公告)日：2010-10-28
申请号：US12762087
申请日：2010-04-16
申请人： Dean Moses , Ed Anuff , Fergus Griffin , Jean Tessier , Hans Akesson , John Petersen , Tom Belunis , Edith Harbaugh , Noah Guyot , Dave MacLeod , Amy Phillips , Ethan Vonderweid
发明人： Dean Moses , Ed Anuff , Fergus Griffin , Jean Tessier , Hans Akesson , John Petersen , Tom Belunis , Edith Harbaugh , Noah Guyot , Dave MacLeod , Amy Phillips , Ethan Vonderweid
IPC分类号： G06F17/30
CPC分类号： H04L67/1095 , G06F17/2247 , G06F17/30867 , G06F17/3089 , G06F17/30893 , G06Q10/10 , H04L29/06 , H04L41/22 , H04L41/28 , H04L63/105 , H04L67/10 , H04L67/1097 , H04L67/2838 , H04L67/2861 , H04L67/306 , H04L69/329
摘要： The sharing of objects may be executed by performing various share type administrations. Objects may be shared directly to a site or may be made available indirectly for reuse by a site. The objects shared and made available for reuse may be added to the site to which they are shared and made available for reuse. References to the objects shared and made available for reuse are stored in repositories in response to, and in accordance with, the share type administration performed. The storage of the references to objects is based on privileges associated with at least one of a repository, a site and a user. Objects made available for reuse by, and shared to, a site may be made unavailable for reuse by, and unshared to, the site through the execution of a share type administration.
摘要翻译：可以通过执行各种共享类型管理来执行对象的共享。对象可以直接共享到一个站点，或者可以被间接地提供给站点重用。共享并可用于重用的对象可以添加到它们共享的站点，并可用于重用。共享并可用于重用的对象的引用响应于并根据执行的共享类型管理而存储在存储库中。对对象的引用的存储基于与存储库，站点和用户中的至少一个相关联的特权。可用于由站点重用和共享的对象可能通过执行共享类型管理而不可用于站点的重用和非共享。

6. 发明授权

US07784568B2 Method and apparatus for controlling tracked vehicles 有权
标题翻译：用于控制跟踪车辆的方法和装置
公开(公告)号：US07784568B2
公开(公告)日：2010-08-31
申请号：US12233284
申请日：2008-09-18
申请人： John Petersen , Eric Poulson
发明人： John Petersen , Eric Poulson
IPC分类号： B62D11/00
CPC分类号： B62D11/003 , B62D11/08
摘要： Apparatus for controlling a track on a tracked vehicle may comprise a drive system, a clutch, a brake, and a track control system to operate the clutch and the brake. A control signal generator operatively associated with the track control system produces control signals that vary at a first rate to cause the track control system to transition the clutch from an engaged state to a disengaged state and produces control signals that vary at a second rate to cause the track control system to transition the brake from an initial application state to a full application state, the second rate being less than the first rate.
摘要翻译：用于控制跟踪车辆上的轨道的装置可以包括驱动系统，离合器，制动器和用于操作离合器和制动器的轨道控制系统。与轨道控制系统可操作地相关联的控制信号发生器产生以第一速率变化的控制信号，以使轨道控制系统将离合器从接合状态转换到分离状态，并产生以第二速率变化的控制信号，轨道控制系统将制动器从初始应用状态转换到完全应用状态，第二速率小于第一速率。

7. 发明申请

US20080234629A1 WATER ELECTROLYSIS TO FACILITATE DRUG DELIVERY BY IONTOPHORESIS 审中-公开
标题翻译：水电解以通过IOPOPHORESIS促进药物递送
公开(公告)号：US20080234629A1
公开(公告)日：2008-09-25
申请号：US12052952
申请日：2008-03-21
申请人： John Petersen
发明人： John Petersen
IPC分类号： A61N1/30
CPC分类号： A61N1/0436 , A61N1/0448
摘要： The present invention is an iontophoretic system that electrolyzes water to enhance the iontophoretic delivery of an active agent. The invention provides a cartridge adapted for use in iontophoretic system comprising electronics associated with a working electrode capable of electrolyzing water and a conductive composition comprising water and at least one active agent wherein the conductive composition has an initial pH in the absence of the flow of current, wherein upon flow of current through the electrode, water is electrolyzed, and the pH of the composition is changed to a second pH thereby providing enhanced iontophoretic delivery of the active agent.
摘要翻译：本发明是电离水以增强活性剂的离子电渗疗法的离子电渗疗法。本发明提供了一种适用于离子电渗疗法的药筒，其包括与能够电解水的工作电极相连的电子器件和包含水和至少一种活性剂的导电组合物，其中导电组合物在不存在电流的情况下具有初始pH 其中，当电流通过电极时，水被电解，并且组合物的pH变为第二pH，从而提供活性剂的增强的离子电渗疗法。

8. 发明授权

US07293070B2 Method and system for deploying web components between portals in a portal framework 有权
标题翻译：在门户框架中的门户之间部署Web组件的方法和系统
公开(公告)号：US07293070B2
公开(公告)日：2007-11-06
申请号：US10091486
申请日：2002-03-07
申请人： Dean Moses , John Petersen , Edith Harbaugh , Miles Chaston , Hans Akesson , David Shue , Sandeep Chauhan , Jean Tessier
发明人： Dean Moses , John Petersen , Edith Harbaugh , Miles Chaston , Hans Akesson , David Shue , Sandeep Chauhan , Jean Tessier
IPC分类号： G06F15/16 , G06F9/44 , G06F9/445
CPC分类号： H04L67/1095 , G06F17/2247 , G06F17/30867 , G06F17/3089 , G06F17/30893 , G06Q10/10 , H04L29/06 , H04L41/22 , H04L41/28 , H04L63/105 , H04L67/10 , H04L67/1097 , H04L67/2838 , H04L67/2861 , H04L67/306 , H04L69/329
摘要： Disclosed are embodiments of a method, system and computer program product for deploying components of a site between systems in a portal framework. In one embodiment, file assets as well as non-file assets of at least one component of a site designated for export are stored as an export file. Non-file assets may be constructed as an extensible markup language fragment, such as an XML fragment, having a predetermined structure. In one embodiment, the site comprises a collection of software objects that can be manipulated by a set of users having assigned privileges defined by permissions associated with each software object in the collection of software objects. The export file is transferred to a remote system such as a web portal. The assets, which are configured to operate on the remote system, are extracted from the export file to a plurality of locations on the remote system.
摘要翻译：公开了用于在门户框架中的系统之间部署站点的组件的方法，系统和计算机程序产品的实施例。在一个实施例中，文件资产以及指定用于导出的站点的至少一个组件的非文件资产被存储为导出文件。非文件资产可以被构造为具有预定结构的可扩展标记语言片段，例如XML片段。在一个实施例中，站点包括软件对象的集合，该对象可以被具有由与软件对象的集合中的每个软件对象相关联的许可所定义的分配权限的一组用户操纵。导出文件被传输到远程系统，如门户网站。配置为在远程系统上操作的资产从导出文件中提取到远程系统上的多个位置。

9. 发明申请

US20070185432A1 ELECTROKINETIC SYSTEM AND METHOD FOR DELIVERING METHOTREXATE 审中-公开
标题翻译：电动系统及其输送方法
公开(公告)号：US20070185432A1
公开(公告)日：2007-08-09
申请号：US11538249
申请日：2006-10-03
申请人： Robert Etheredge , Dennis Goldberg , Phillip Friden , John Petersen
发明人： Robert Etheredge , Dennis Goldberg , Phillip Friden , John Petersen
IPC分类号： A61N1/30
CPC分类号： A61B17/205 , A61M37/0015 , A61M2037/0061
摘要： The electrokinetic methotrexate delivery system includes at least one applicator having a multiplicity of non-conductive micro-needles carried on a non-conductive surface of the applicator. The opposite surface is formed of electrically conductive material for contact with an active electrode. The applicator includes a matrix containing a medicament, e.g., methotrexate, or a carrier therefor between the opposite surfaces. When the applicator is applied to the individual's skin with the micro-needles penetrating the skin, an electrical current is completed through the power source, the active electrode, methotrexate, or electrically conductive carrier therefor, the targeted treatment site, the individual's body, a ground electrode and the power supply, thereby electokinetically driving the medicament through the non-conductive micro-needles into the targeted treatment site.
摘要翻译：电动氨甲蝶呤递送系统包括至少一个施用器，其具有承载在施用器的非导电表面上的多个非导电微针。相对表面由用于与有源电极接触的导电材料形成。施用器包括在相对表面之间包含药物，例如甲氨蝶呤或其载体的基质。当施用器被微针穿透皮肤施加到个体的皮肤上时，通过电源，有效电极，甲氨蝶呤或导电载体，目标治疗部位，个体的身体，接地电极和电源，从而通过非导电微针将药物电动驱动到目标治疗部位。

10. 发明授权

US08924411B2 System and method for the dynamic provisioning of static content 有权
标题翻译：动态配置静态内容的系统和方法
公开(公告)号：US08924411B2
公开(公告)日：2014-12-30
申请号：US11444023
申请日：2006-05-31
申请人： N. Isaac Rajkumar , Mark McCalister , Expeditus Bolanos , Peter Hale , Mark Martin , Richard Nemec , Puhong You , Daun DeFrance , Ching-Fu Chang , Priya Reddy , Ladislav Kis , Robert L. Patterson , Tony Zgarba , Jeffrey M. Collins , Michael C. Tulkoff , Miles Chaston , Dean Moses , John Petersen , Ian Stahl , Lara Long
发明人： N. Isaac Rajkumar , Mark McCalister , Expeditus Bolanos , Peter Hale , Mark Martin , Richard Nemec , Puhong You , Daun DeFrance , Ching-Fu Chang , Priya Reddy , Ladislav Kis , Robert L. Patterson , Tony Zgarba , Jeffrey M. Collins , Michael C. Tulkoff , Miles Chaston , Dean Moses , John Petersen , Ian Stahl , Lara Long
IPC分类号： G06F17/30 , G06F17/00
CPC分类号： G06F17/30893 , G06F17/30011 , G06F17/3089 , G06F17/30902 , H04L67/02
摘要： Disclosed herein are embodiments of a system and method for the dynamic provisioning of static content. In one embodiment, information presented on a content delivery system can be refreshed based on information published on a content management system. One embodiment can interface the content delivery system and the content management system at the page level. More specifically, content dependencies across pages employing the same content or portion(s) thereof can be tracked in a timely, accurate manner. Upon receiving a notification of a change to the content or a portion thereof from the content management system, a content generation system may operate to determine, based on the dependencies, what pages are affected by the change and, based on the determination, dynamically regenerate any and all affected pages. The regenerated pages may then be stored and/or pushed to the web tier for delivery to end users.
摘要翻译：这里公开了用于静态内容的动态供应的系统和方法的实施例。在一个实施例中，呈现在内容递送系统上的信息可以基于在内容管理系统上发布的信息来刷新。一个实施例可以在页面级别上与内容传送系统和内容管理系统接口。更具体地，可以以及时，准确的方式跟踪在采用相同内容或部分的页面上的内容相关性。在从内容管理系统接收到对内容或其一部分的改变的通知时，内容生成系统可以操作以基于相关性来确定哪些页面受到该改变的影响，并且基于该确定动态地再现任何和所有受影响的页面。然后可以将再生页面存储和/或推送到web层以递送给最终用户。

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