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1. 发明授权

US06217774B1 Simulated moving bed separation apparatus 失效
标题翻译：模拟移动床分离装置
公开(公告)号：US06217774B1
公开(公告)日：2001-04-17
申请号：US09476354
申请日：2000-01-03
申请人： Shinji Nagamatsu , Koichi Murazumi
发明人： Shinji Nagamatsu , Koichi Murazumi
IPC分类号： B01D1508
CPC分类号： B01D15/1828 , B01D15/1842 , B01D2215/023
摘要： This invention is intended to provide a simulated moving bed separation apparatus which is able to monitor concentration distribution of components in the fluid circulation passage or a simulated moving bed separation apparatus which is able to automatically control the operation conditions to optimum and provides a simulated moving bed apparatus provided with concentration detectors installed in the fluid circulation passage and means for measuring concentrations installed at outlets of the fluid circulation passage.
摘要翻译：本发明旨在提供一种模拟移动床分离装置，其能够监测流体循环通道中的部件的浓度分布或模拟移动床分离装置，其能够自动控制操作条件以最佳化并提供模拟移动床设置有安装在流体循环通道中的浓度检测器的装置和用于测量安装在流体循环通道的出口处的浓度的装置。

2. 发明授权

US6117343A Filler-packing apparatus, filler-packing method, and filler-packed column assembly 失效
标题翻译：填料包装设备，填料填充方法和填料填充柱组件
公开(公告)号：US6117343A
公开(公告)日：2000-09-12
申请号：US91890
申请日：1998-06-26
申请人： Shinji Nagamatsu , Koichi Murazumi
发明人： Shinji Nagamatsu , Koichi Murazumi
IPC分类号： B01D15/02 , B01J8/02 , B65B3/00 , G01N30/56 , B01D24/38
CPC分类号： G01N30/56 , G01N2030/565
摘要： A filler-packing apparatus comprises a bundled filler-receiving space assembly, a movable bottom stopper assembly having bottom stoppers which are insertable into bottom openings of the filler-receiving spaces of said assembly, and top stoppers which are respectively insertable into top openings of the filler-receiving spaces and enabling packing filler in a plurality of columns in a short period of time. A filler-packing method uses this apparatus and thereby enables packing of the filler into the filler-receiving spaces in short period of time uniformly. An assembly of columns is uniformly packed with a filler and assembled by using the filler-packing apparatus and the filler-packing method.
摘要翻译： PCT No.PCT / JP96 / 03708 Sec。 371日期：1998年6月26日 102（e）日期1998年6月26日PCT 1996年12月19日PCT PCT。出版物WO97 / 24612 PCT 日期1997年7月10日一种填料包装设备包括一个捆扎的填料容纳空间组件，一个可移动的底部止动器组件，其具有可以插入到所述组件的填料容纳空间的底部开口中的底部止动器，以及分别可插入的顶部止动件在填充物接收空间的顶部开口中，并且能够在短时间内使多个列中的包装填料成为可能。填料填充方法使用该装置，从而能够在短时间内将填料填充到填料接收空间中。柱的组装均匀地填充填料并通过使用填料填充装置和填料填充方法组装。

3. 发明授权

US5032281A Separating membrane and separation method 失效
标题翻译：分离膜和分离方法
公开(公告)号：US5032281A
公开(公告)日：1991-07-16
申请号：US556293
申请日：1990-07-20
申请人： Shinji Nagamatsu , Yoshikazu Tanaka , Tohru Shibata
发明人： Shinji Nagamatsu , Yoshikazu Tanaka , Tohru Shibata
IPC分类号： A61M1/16 , A61M1/34 , B01D39/16 , B01D61/00 , B01D67/00 , B01D69/02 , C12Q1/68 , G01N33/544
CPC分类号： B01D67/0093 , B01D39/16 , B01D61/00 , B01D69/02 , C12Q1/68 , G01N33/544 , A61M1/1656 , A61M1/3455
摘要： A separating membrane having a porous membrane structure with a pore size distribution such that the membrane does not permeate 90 percent or more of particles having a size of 0.5 micron when the membrane is 0.1 mm thick. The membrane is composed of a material having a nitrogen-containing compound and is liquid-permeable to adsorb and retain phosphopolyols contained in a liquid.

4. 发明授权

US4909942A Process for removing pyrogens 失效
标题翻译：去除热原的方法
公开(公告)号：US4909942A
公开(公告)日：1990-03-20
申请号：US256729
申请日：1988-10-12
申请人： Tadashi Sato , Taizo Watanabe , Satoshi Minobe , Takashi Nishimura , Masahiro Kagotani , Tomonobu Ase , Zenjiro Honda , Shinji Nagamatsu
发明人： Tadashi Sato , Taizo Watanabe , Satoshi Minobe , Takashi Nishimura , Masahiro Kagotani , Tomonobu Ase , Zenjiro Honda , Shinji Nagamatsu
IPC分类号： A61K9/08 , A61L2/02 , B01D15/00 , B01D61/14 , B01D61/58 , C02F1/28 , C02F1/44
CPC分类号： B01D61/145 , A61L2/022 , B01D15/00 , C02F1/444
摘要： Pyrogens are removed out of a solution thereof by (1) treating the solution with a membrane and then (2) treating the resulting solution with a pyrogen adsorbent. The obtained solution is useful in pharmaceutical fields.

5. 发明授权

US06544413B1 Simulated moving bed device 有权
标题翻译：模拟移动床装置
公开(公告)号：US06544413B1
公开(公告)日：2003-04-08
申请号：US09869574
申请日：2001-10-09
申请人： Shinji Nagamatsu , Oliver Ludemann-Hombourger , Julien Filou
发明人： Shinji Nagamatsu , Oliver Ludemann-Hombourger , Julien Filou
IPC分类号： B01D35157
CPC分类号： B01D15/1842 , B01D2215/023
摘要： This invention provides an ultra-micro simulated moving bed apparatus employing valve devices, each of which is applied to each unit column and comprises an eluent valve that opens or closes a first communication passage connecting an eluent feeding cul-de-sac passage with the circulation passage, an extract valve that opens or closes a second communication passage connecting an extract draw-out cul-de-sac passage with the circulation passage, a feedstock mixture valve that opens or closes a third communication passage connecting a feedstock mixture feeding cul-de-sac passage with the circulation passage, and a raffinate valve that opens or closes a fourth communication passage connecting a raffinate draw-out cul-de-sac passage with the circulation passage. By employment of the valve devices can be provided an ultra-micro simulated moving bed apparatus that has a small volume of the fluid flowable spaces, good operation stability, quick return to a stable operation after changing the operation conditions, and high separation efficiency.
摘要翻译：本发明提供了一种采用阀装置的超微型模拟移动床装置，每个装置应用于每个单元柱，并且包括洗脱阀，其将打开或关闭连接洗脱液进料通道与循环的第一连通通道通道，打开或关闭连接抽出物抽出通道与循环通道的第二连通通道的抽取阀，打开或关闭连接原料混合物的第三连通通道的原料混合阀，具有循环通道的通道;以及抽吸阀，其打开或关闭连接抽出物抽出通道与循环通道的第四连通通道。通过使用阀门装置，可以提供具有体积小的流体流动空间的超微型模拟移动床装置，操作稳定性好，改变操作条件后快速恢复到稳定的操作，并且分离效率高。

6. 发明授权

US5136032A Method for separating phosphopolyol compounds using a separating agent 失效
标题翻译：使用分离剂分离磷酸酯化合物的方法
公开(公告)号：US5136032A
公开(公告)日：1992-08-04
申请号：US619937
申请日：1990-11-29
申请人： Shinji Nagamatsu , Yoshikazu Tanaka , Thoru Shibata
发明人： Shinji Nagamatsu , Yoshikazu Tanaka , Thoru Shibata
IPC分类号： C12N15/09 , A61M1/16 , A61M1/34 , B01D15/00 , B01D39/14 , B01D39/16 , B01D61/00 , B01D67/00 , B01D69/00 , B01D69/02 , B01J20/26 , C02F1/28 , C02F1/44 , C12N15/00 , C12Q1/68 , G01N33/544
CPC分类号： B01D67/0093 , B01D39/14 , B01D39/16 , B01D61/00 , B01D69/02 , C12Q1/68 , G01N33/544 , A61M1/1656 , A61M1/3455 , B01D2323/30
摘要： A phosphopolyol compound, such as pyrogens, is separated from a solution to be used in the pharmaceutical field by bringing the solution into contact with a porous adsorbent which has a pore size of 1 nm to 20 microns and comprises a base material and a functional chain group of an aliphatic amine having a chain length of 2 to 50, bonded to the base material.
摘要翻译：通过使溶液与孔径为1nm至20微米的多孔吸附剂接触，将磷光多酚化合物（例如热原）与用于制药领域的溶液分离，并且包含基材和功能链一组链长为2〜50的脂肪族胺，与基材结合。

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