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1. 发明申请

US20090253658A1 Fat Accumulation Inhibitor 审中-公开
标题翻译：脂肪蓄积抑制剂
公开(公告)号：US20090253658A1
公开(公告)日：2009-10-08
申请号：US12296222
申请日：2007-04-06
申请人： Reo Tanaka , Tomoyuki Isogai , Yuko Haruta , Susumu Miura , Ken Kato , Toshimitsu Yoshioka , Hiroshi Kawakami , Satoshi Higurashi , Hiroaki Matsuyama
发明人： Reo Tanaka , Tomoyuki Isogai , Yuko Haruta , Susumu Miura , Ken Kato , Toshimitsu Yoshioka , Hiroshi Kawakami , Satoshi Higurashi , Hiroaki Matsuyama
IPC分类号： A61K31/66 , C07F9/06
CPC分类号： A61K35/20 , A23L2/52 , A23L33/19 , A23V2002/00 , A61K31/661 , A23V2200/332 , A23V2250/1844
摘要： To provide a fat accumulation inhibitor and a food or drink for inhibiting fat accumulation, a visceral fat accumulation inhibitor and a food or drink for inhibiting visceral fat accumulation, or an agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.A fat accumulation inhibitor for a fat cell, which comprises a milk-derived phospholipid as an active ingredient, and a food or drink for inhibiting fat accumulation in a fat cell, which comprises a milk-derived phospholipid. A visceral fat accumulation inhibitor comprising a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for inhibiting visceral fat accumulation. An agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which comprises a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.
摘要翻译：提供一种脂肪蓄积抑制剂和用于抑制脂肪蓄积的食物或饮料，内脏脂肪蓄积抑制剂和用于抑制内脏脂肪蓄积的食品或饮料，或用于加速和/或抑制血液中脂联素浓度降低的试剂，以及用于促进血液中脂联素浓度增加和/或抑制降低的食物或饮料。一种脂肪蓄积抑制剂，其包含乳源性磷脂作为活性成分的脂肪蓄积抑制剂，以及包含乳源性磷脂的脂肪细胞中抑制脂肪蓄积的食品或饮料。含有鞘氨醇的磷脂或其衍生物作为活性成分的内脏脂肪蓄积抑制剂和抑制内脏脂肪蓄积的食品或饮料。用于促进增加和/或抑制血液中脂联素浓度降低的药物，其包含含鞘氨醇的磷脂或其衍生物作为活性成分，以及用于加速和/或抑制脂联素浓度降低的食品或饮料在血中

2. 发明申请

US20120077780A1 Fat Accumulation Inhibitor and Method of Use Thereof 审中-公开
标题翻译：脂肪蓄积抑制剂及其使用方法
公开(公告)号：US20120077780A1
公开(公告)日：2012-03-29
申请号：US13240739
申请日：2011-09-22
申请人： Reo Tanaka , Tomoyuki Isogai , Yuko Haruta , Susumu Miura , Ken Kato , Toshimitsu Yoshioka , Hiroshi Kawakami , Satoshi Higurashi , Hiroaki Matsuyama
发明人： Reo Tanaka , Tomoyuki Isogai , Yuko Haruta , Susumu Miura , Ken Kato , Toshimitsu Yoshioka , Hiroshi Kawakami , Satoshi Higurashi , Hiroaki Matsuyama
IPC分类号： A61K31/688 , A61K31/685 , A61P3/04 , A61K31/683
CPC分类号： A61K35/20 , A23L2/52 , A23L33/19 , A23V2002/00 , A61K31/661 , A23V2200/332 , A23V2250/1844
摘要： The present disclosure relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a fat accumulation inhibitor for a fat cell which includes a milk-derived phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of inhibiting a visceral fat accumulation in a subject, which includes administering the visceral fat accumulation inhibitor which includes a sphingosine-containing phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which includes administering an agent which includes a sphingosine-containing phospholipid as an active ingredient to the blood. The present disclosure also relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a milk-derived phospholipid to a subject.
摘要翻译：本公开涉及抑制受试者中的脂肪细胞的脂肪蓄积的方法，其包括向受试者施用包含作为有效成分的乳源性磷脂的脂肪细胞的脂肪蓄积抑制剂。本公开还涉及抑制受试者内脏脂肪蓄积的方法，其包括向受试者施用含有鞘氨醇的磷脂作为活性成分的内脏脂肪蓄积抑制剂。本公开还涉及一种促进血液中脂联素浓度增加和/或抑制降低的方法，其包括向血液中施用含有鞘氨醇的磷脂作为活性成分的药剂。本公开还涉及抑制受试者中的脂肪细胞的脂肪蓄积的方法，其包括向受试者施用乳源性磷脂。

3. 发明授权

US08921342B2 Liver function-protecting agent 有权
标题翻译：肝功能保护剂
公开(公告)号：US08921342B2
公开(公告)日：2014-12-30
申请号：US12811744
申请日：2009-01-15
申请人： Tomoyuki Isogai , Yukio Kadooka , Reo Tanaka , Akira Tomizawa
发明人： Tomoyuki Isogai , Yukio Kadooka , Reo Tanaka , Akira Tomizawa
IPC分类号： A61K35/20 , A61K47/24 , A61K31/7032 , A23L1/30 , A23L2/52 , A23K1/16
CPC分类号： A23L1/30 , A23K20/158 , A23L2/52 , A23L33/10 , A23L33/115 , A61K31/7032 , A61K35/20
摘要： Disclosed is a liver function-protecting agent which comprises a phospholipid as an active ingredient, and which can exhibit an excellent prophylactic and ameliorating effect on the deterioration in the liver function when ingested orally. Also disclosed is a liver function-protecting food, beverage or feed. The phospholipid is preferably one derived from milk or a milk material. Alternatively, the phospholipid may be used in the form of a phospholipid-containing composition prepared from milk or a milk material and containing the phospholipid in an amount of 10 wt % or more relative to the total solid content.
摘要翻译：公开了一种肝功能保护剂，其包含磷脂作为活性成分，并且对于口服摄入时肝脏功能的退化具有优异的预防和改善作用。还公开了肝功能保护食品，饮料或饲料。磷脂最好是从牛奶或乳制品中得到的。或者，磷脂可以以由乳或乳材料制备并含有相对于总固体含量为10重量％以上的量的磷脂的含磷脂组合物的形式使用。

4. 发明申请

US20100279985A1 LIVER FUNCTION-PROTECTING AGENT 有权
标题翻译：肝功能保护剂
公开(公告)号：US20100279985A1
公开(公告)日：2010-11-04
申请号：US12811744
申请日：2009-01-15
申请人： Tomoyuki Isogai , Yukio Kadooka , Reo Tanaka , Akira Tomizawa
发明人： Tomoyuki Isogai , Yukio Kadooka , Reo Tanaka , Akira Tomizawa
IPC分类号： A61K31/7028 , A61P1/16 , C07F9/09
CPC分类号： A23L1/30 , A23K20/158 , A23L2/52 , A23L33/10 , A23L33/115 , A61K31/7032 , A61K35/20
摘要： Disclosed is a liver function-protecting agent which comprises a phospholipid as an active ingredient, and which can exhibit an excellent prophylactic and ameliorating effect on the deterioration in the liver function when ingested orally. Also disclosed is a liver function-protecting food, beverage or feed. The phospholipid is preferably one derived from milk or a milk material. Alternatively, the phospholipid may be used in the form of a phospholipid-containing composition prepared from milk or a milk material and containing the phospholipid in an amount of 10 wt % or more relative to the total solid content.
摘要翻译：公开了一种肝功能保护剂，其包含磷脂作为活性成分，并且对于口服摄入时肝脏功能的退化具有优异的预防和改善作用。还公开了肝功能保护食品，饮料或饲料。磷脂最好是从牛奶或乳制品中得到的。或者，磷脂可以以由乳或乳材料制备并含有相对于总固体含量为10重量％以上的量的含磷脂的组合物的形式使用。

5. 发明授权

US09695780B2 Internal combustion engine 有权
公开(公告)号：US09695780B2
公开(公告)日：2017-07-04
申请号：US14365355
申请日：2012-03-05
申请人： Takahiro Sadamitsu , Atsushi Nakagaki , Osamu Maeda , Tomoyuki Isogai , Tatsuo Iida , Koichi Yonezawa
发明人： Takahiro Sadamitsu , Atsushi Nakagaki , Osamu Maeda , Tomoyuki Isogai , Tatsuo Iida , Koichi Yonezawa
IPC分类号： F02B47/08 , F02M25/07 , F02B39/00 , F01M13/02 , F01D17/10 , F02B37/16 , F02M25/08
CPC分类号： F02M26/09 , F01D17/105 , F01M13/022 , F01M2013/027 , F02B37/16 , F02B39/00 , F02M25/08 , F05D2220/40 , F05D2260/14 , F05D2260/606 , Y02T10/144
摘要： A second recirculation passage recirculates blow-by gas at an upstream section, which is upstream of an impeller of a turbocharger in an intake passage. A first passage branches and extends from a downstream section, which is downstream of the impeller in the intake passage. A second passage that forms part of the second recirculation passage connects the first passage and the upstream section to each other. A third passage, which is provided separately from the second passage, connects the first passage and the upstream section to each other. A change mechanism changes, in different manners, the flow rate of compressed gas recirculating to the upstream section through the second passage, and the flow rate of compressed gas recirculating to the upstream section through the third passage.

6. 发明授权

US09388821B2 Compressor housing and exhaust turbine supercharger 有权
标题翻译：压缩机外壳和排气涡轮增压器
公开(公告)号：US09388821B2
公开(公告)日：2016-07-12
申请号：US14113293
申请日：2011-07-25
申请人： Tomoyuki Isogai
发明人： Tomoyuki Isogai
IPC分类号： F04D29/16 , F01D25/24 , F02B33/02 , F02C6/12
CPC分类号： F04D29/162 , F01D25/24 , F02B33/02 , F02C6/12 , F05D2220/40 , F05D2240/11
摘要： A compressor housing is provided with a shroud member, which surrounds a compressor impeller, and a sealing member. The shroud member has a facing surface that is located at a position on a radially outside of the compressor impeller on an inner circumferential surface of the shroud member. The sealing member is provided on the facing surface. The sealing member is formed from a cylindrical material that has free-cutting property to the compressor impeller. The sealing member is press-fitted into the facing surface of the shroud member.
摘要翻译：压缩机壳体设置有围绕压缩机叶轮的护罩构件和密封构件。护罩构件具有面对表面，该面对面位于在护罩构件的内周面上的压缩机叶轮的径向外侧的位置。密封构件设置在相对表面上。密封构件由对压缩机叶轮具有自由切割性的圆柱形材料形成。密封构件被压配合到护罩构件的相对表面中。

7. 发明申请

US20140119907A1 TURBINE HOUSING AND EXHAUST GAS TURBINE SUPERCHARGER 有权
标题翻译：涡轮机外壳和排气涡轮增压器
公开(公告)号：US20140119907A1
公开(公告)日：2014-05-01
申请号：US13511060
申请日：2011-07-06
申请人： Osamu Maeda , Kouji Nagai , Tomoyuki Isogai , Hiroki Matsui , Masanori Saeki
发明人： Osamu Maeda , Kouji Nagai , Tomoyuki Isogai , Hiroki Matsui , Masanori Saeki
IPC分类号： F04D29/40
CPC分类号： F04D29/40 , F01D9/026 , F02C6/12 , F05D2220/40 , F05D2230/54
摘要： A turbine housing includes an outer housing member, which has a proximal housing portion and a distal housing portion, and an inner housing member, which is provided inside the outer housing member and has a shroud surface that faces a turbine wheel in an axial direction. A distal portion of the inner housing member serves as a slide portion slidable in the axial direction. Further, a proximal portion of the inner housing member is fixed to the proximal housing portion at a part closer to a distal side than a proximal portion of the proximal housing portion. Further, a scroll portion is formed by the inner housing member and a proximal scroll portion of the proximal housing portion located closer to a proximal side than the inner housing member.
摘要翻译：涡轮壳体包括具有近侧壳体部分和远侧壳体部分的外部壳体构件和设置在外部壳体构件内部并且具有沿轴向面向涡轮机叶轮的护罩表面的内部壳体构件。内部壳体构件的远端部分用作可沿轴向滑动的滑动部分。此外，内壳体构件的近端部分在近侧壳体部分的近侧部分处更靠近远端侧的部分处固定到近侧壳体部分。此外，涡卷部分由内壳体构件和近侧壳体部分的近侧涡卷部分形成，其位于比内壳体构件更靠近基端侧。

8. 发明授权

US09435346B2 Compressor housing for supercharger and method for manufacturing the same 有权
标题翻译：增压器用压缩机壳体及其制造方法
公开(公告)号：US09435346B2
公开(公告)日：2016-09-06
申请号：US13642934
申请日：2011-03-30
申请人： Ryu Osuka , Hiroki Matsui , Tomoyuki Isogai
发明人： Ryu Osuka , Hiroki Matsui , Tomoyuki Isogai
IPC分类号： F02B39/00 , F04D29/02 , B22C9/24 , B22D17/00 , F04D29/42 , F04D29/44 , F04D29/62 , B23P17/00
CPC分类号： F04D29/023 , B22C9/24 , B22D17/00 , F04D29/4206 , F04D29/441 , F04D29/624 , F05D2220/40 , F05D2230/21 , F05D2250/52 , F05D2260/37 , Y10T29/49243
摘要： In a compressor housing, a scroll piece includes a cylindrical intake port forming section, a scroll wall surface forming section that forms an air-intake side wall surface of a discharge scroll chamber, and a scroll outer circumferential section that covers an outer circumferential side of the discharge scroll chamber. A shroud piece of the housing includes a cylindrical shroud press fitted section press fitted into the intake port forming section, and a shroud wall surface forming section that forms an inner circumferential side wall surface of the discharge scroll chamber and also forms a shroud surface that opposes an impeller and a diffuser surface. An outer circumferential annular piece of the housing includes an outer circumferential annular press fitted section press fitted inside the scroll outer circumferential section, and an outer circumferential annular wall surface forming section that forms an outer circumferential side wall surface of the discharge scroll chamber.
摘要翻译：在压缩机壳体中，涡旋件包括圆柱形进气口形成部分，形成排出涡旋室的进气侧壁面的涡旋壁表面形成部分和覆盖排出涡旋室的进气侧壁面的涡旋壁外周部分，排出涡旋室。所述壳体的护罩片包括压入到所述进气口形成部中的圆筒形罩压配合部，以及形成所述排出涡旋室的内周侧壁面的护罩壁形成部，并且还形成与所述排出侧壁叶轮和扩散器表面。壳体的外周环状片包括压配合在涡旋外周部内的外周环形压配合部分和形成排出涡旋室的外周侧壁面的外周环形壁面形成部。

9. 发明授权

US09261109B2 Turbine housing and exhaust gas turbine supercharger 有权
标题翻译：涡轮机外壳和废气涡轮增压器
公开(公告)号：US09261109B2
公开(公告)日：2016-02-16
申请号：US13511060
申请日：2011-07-06
申请人： Osamu Maeda , Kouji Nagai , Tomoyuki Isogai , Hiroki Matsui , Masanori Saeki
发明人： Osamu Maeda , Kouji Nagai , Tomoyuki Isogai , Hiroki Matsui , Masanori Saeki
IPC分类号： F04D29/40 , F01D9/02 , F02C6/12
CPC分类号： F04D29/40 , F01D9/026 , F02C6/12 , F05D2220/40 , F05D2230/54
摘要： A turbine housing includes an outer housing member, which has a proximal housing portion and a distal housing portion, and an inner housing member, which is provided inside the outer housing member and has a shroud surface that faces a turbine wheel in an axial direction. A distal portion of the inner housing member serves as a slide portion slidable in the axial direction. Further, a proximal portion of the inner housing member is fixed to the proximal housing portion at a part closer to a distal side than a proximal portion of the proximal housing portion. Further, a scroll portion is formed by the inner housing member and a proximal scroll portion of the proximal housing portion located closer to a proximal side than the inner housing member.
摘要翻译：涡轮壳体包括具有近侧壳体部分和远侧壳体部分的外部壳体构件和设置在外部壳体构件内部并且具有沿轴向面向涡轮机叶轮的护罩表面的内部壳体构件。内部壳体构件的远端部分用作可沿轴向滑动的滑动部分。此外，内壳体构件的近端部分在近侧壳体部分的近侧部分处更靠近远端侧的部分处固定到近侧壳体部分。此外，涡卷部分由内壳体构件和近侧壳体部分的近侧涡卷部分形成，其位于比内壳体构件更靠近基端侧。

10. 发明申请

US20130323034A1 ROTARY MACHINE 有权
标题翻译：旋转机
公开(公告)号：US20130323034A1
公开(公告)日：2013-12-05
申请号：US13985137
申请日：2012-02-01
申请人： Tomoyuki Isogai
发明人： Tomoyuki Isogai
IPC分类号： F01D11/12
CPC分类号： F01D11/122 , F01D5/20 , F04D29/023 , F04D29/162 , F04D29/4206 , F05D2220/40 , F05D2230/10
摘要： In a compressor (11) of a turbocharger (1), a compressor wheel (14) is provided in a housing (12) to be capable of rotating. When the wheel (14) rotates, air suctioned through an inlet of the housing (12) is compressed and then discharged through an outlet of the housing, (12). Further, an abradable seal layer (16) formed on an inner surface of the housing (12) is abraded by a vane (13) of the rotating wheel (14) such that a tip clearance between the vane (13) and a part of the inner surface of the housing (12) that opposes the vane (13) is adjusted. A corner portion (13a) of the vane (13) on the outlet side of the housing (12) is shaped to move gradually further away from a shroud curve (Lc) of the seal layer (16) toward an end portion of the vane (13) on the outlet side of the housing (12).
摘要翻译：在涡轮增压器（1）的压缩机（11）中，压缩机叶轮（14）设置在壳体（12）中以能够旋转。当轮（14）旋转时，通过壳体（12）的入口抽吸的空气被压缩，然后通过壳体（12）的出口排出。此外，形成在壳体（12）的内表面上的可磨损的密封层（16）被旋转轮（14）的叶片（13）磨损，使得叶片（13）和一部分调节与叶片（13）相对的壳体（12）的内表面。在壳体（12）的出口侧上的叶片（13）的角部（13a）被成形为逐渐远离密封层（16）的护罩曲线（Lc）朝向叶片的端部（13）在所述壳体（12）的出口侧。

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