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1. 发明申请

US20060180255A1 Pneumatic tire with tread having electrically conductive component underlying and extending through its tread 有权
标题翻译：具有胎面的气动轮胎具有导电部件，并且穿过其胎面延伸
公开(公告)号：US20060180255A1
公开(公告)日：2006-08-17
申请号：US11349833
申请日：2006-02-08
申请人： Peter Marriott , David Jenkins , Howard Waldron
发明人： Peter Marriott , David Jenkins , Howard Waldron
IPC分类号： B60C19/08
CPC分类号： B60C19/08 , Y10S152/02
摘要： This invention relates to a pneumatic rubber tire having a circumferential tread containing an outer tread rubber layer, wherein said outer tread rubber layer contains an outer tire running surface, comprised of an electrically insulating (poorly electrically conducting) rubber composition and wherein said tread additionally contains a circumferential tread component in a form of an inverted “T” configuration comprised of a relatively electrically conducting rubber composition (relative to said outer tread rubber strip) wherein the stem of said inverted “T” configured tread component extends through said outer tread rubber layer to its running surface to thereby provide a path of least electrical resistance through said outer tread strip to its running surface and wherein the base of said “T” configured tread component underlies a portion of said outer tread rubber layer and is less than, and therefore not entirely co-extensive with, the axial width of said outer tread rubber layer.
摘要翻译：本发明涉及一种具有包含外胎面橡胶层的周向胎面的气动橡胶轮胎，其中所述外胎面橡胶层包含外轮胎运行表面，其由电绝缘（导电不良）橡胶组合物组成，并且其中所述胎面还包含由相对导电的橡胶组合物（相对于所述外胎面橡胶条）组成的倒置“T”构型形式的周向胎面部件，其中所述倒置的“T”构造的胎面部件的柄部延伸穿过所述外胎面橡胶层到其运行表面，从而提供通过所述外胎面带到其运行表面的最小电阻的路径，并且其中所述“T”构造的胎面部件的底部位于所述外胎面橡胶层的一部分之下，并且因此小于不完全与所述外胎面橡胶层的轴向宽度共同扩大。

2. 发明授权

US09290573B2 Therapeutic low density lipoprotein-related protein 6 (LRP6) multivalent antibodies 有权
标题翻译：治疗性低密度脂蛋白相关蛋白6（LRP6）多价抗体
公开(公告)号：US09290573B2
公开(公告)日：2016-03-22
申请号：US13696372
申请日：2011-05-05
申请人： Feng Cong , Seth Ettenberg , David Jenkins , Ming Lei , Andreas Loew , Karen Vincent , Li Zhou
发明人： Feng Cong , Seth Ettenberg , David Jenkins , Ming Lei , Andreas Loew , Karen Vincent , Li Zhou
IPC分类号： C07K16/28 , C07K16/46 , A61K39/395 , A61K39/00
CPC分类号： C07K16/2863 , A61K39/395 , A61K39/3955 , A61K2039/505 , C07K16/28 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/55 , C07K2317/622 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/00
摘要： The present disclosure relates to an antibody or antigen binding fragment having at least two receptor binding domains for two different binding sites of LRP6 and compositions and methods of use thereof.
摘要翻译：本公开涉及具有至少两个LRP6的两个不同结合位点的受体结合结构域的抗体或抗原结合片段及其组合物及其使用方法。

3. 发明授权

US08207306B2 Targeted binding agents directed to sonic hedgehog homolog and uses thereof 失效
标题翻译：针对声音刺猬蛋白同源物的靶向结合剂及其用途
公开(公告)号：US08207306B2
公开(公告)日：2012-06-26
申请号：US12562435
申请日：2009-09-18
申请人： David Jenkins , Neil Michaud , Naomi Laing , Jaspal Singh Kang
发明人： David Jenkins , Neil Michaud , Naomi Laing , Jaspal Singh Kang
IPC分类号： C07K16/00 , C12P21/08 , C07K1/00
CPC分类号： C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The invention relates to targeted binding agents against human sonic hedgehog homolog (Shh) and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to Shh. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of Shh and as diagnostics.
摘要翻译：本发明涉及针对人类声波刺猬蛋白同源物（Shh）的靶向结合剂及其用途。更具体地，本发明涉及针对Shh的完全人单克隆抗体。所描述的靶向结合剂可用于治疗与Shh的活性和/或过量产生相关的疾病和作为诊断。

4. 发明授权

US08192738B2 Targeted antibodies directed to DLL4 有权
标题翻译：针对DLL4的靶向抗体
公开(公告)号：US08192738B2
公开(公告)日：2012-06-05
申请号：US12562268
申请日：2009-09-18
申请人： Vahe Bedian , David Jenkins , Ian Foltz
发明人： Vahe Bedian , David Jenkins , Ian Foltz
IPC分类号： A61K39/395 , C07K16/18 , C07K14/435
CPC分类号： C07K16/28 , A61K39/395 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/475 , C07K16/22 , C07K2317/565 , C07K2317/92
摘要： The invention relates to targeted binding agents against DLL4 and uses of such agents. More specifically, the invention relates to fully human monoclonal antibodies directed to DLL4. The described targeted binding agents are useful in the treatment of diseases associated with the activity and/or overproduction of DLL4 and as diagnostics.
摘要翻译：本发明涉及针对DLL4的靶向结合剂及其用途。更具体地，本发明涉及针对DLL4的完全人单克隆抗体。所描述的靶向结合剂可用于治疗与DLL4的活性和/或过量产生相关的疾病和作为诊断。

5. 外观设计

USD641888S1 Baby bottle 有权
标题翻译：婴儿奶瓶
公开(公告)号：USD641888S1
公开(公告)日：2011-07-19
申请号：US29368511
申请日：2010-08-25
申请人： David Jenkins , Ashley Jenkins
设计人： David Jenkins , Ashley Jenkins

6. 发明申请

US20070292077A1 Beam steering element with built-in detector and system for use thereof 失效
公开(公告)号：US20070292077A1
公开(公告)日：2007-12-20
申请号：US11796550
申请日：2007-04-27
申请人： Roger Holmstrom , Miriam Qunell , David Jenkins
发明人： Roger Holmstrom , Miriam Qunell , David Jenkins
IPC分类号： G02B26/08 , B05D5/06 , G02B6/26 , H01L21/84 , C23F1/00
CPC分类号： G02B6/3588 , G02B6/26 , G02B6/3512 , G02B26/08 , G02B26/0841
摘要： An all-optical cross-connect switching system provides optical switching that may reduce processing requirements by three orders of magnitude over conventional techniques by associating at least one optical detector with an optical beam steering element. In one embodiment, a first beam steering element, having a reflective surface in optical association with a first optical fiber array, and a second beam steering element, having a reflective surface in optical association with a second optical fiber array, are optically arranged to direct an optical beam from a first optical fiber in the first optical fiber array to a second optical fiber in the second optical fiber array. The optical detector provides information about a first position of the optical beam on the second beam steering element. Based on this information, the angle of the first beam steering element may be adjusted to cause the optical beam to change to a second position on the second beam steering element.

7. 发明授权

US07231114B2 Multimode fiber optical fiber transmission system with offset launch single mode long wavelength vertical cavity surface emitting laser transmitter 有权
标题翻译：多模光纤光纤传输系统具有偏移发射单模长波长垂直腔表面发射激光发射器
公开(公告)号：US07231114B2
公开(公告)日：2007-06-12
申请号：US10851484
申请日：2004-05-22
申请人： David Jenkins , Christopher Park
发明人： David Jenkins , Christopher Park
IPC分类号： G02B6/42
CPC分类号： G02B6/4206 , G02B6/3893 , G02B6/4246 , G02B6/4292 , H01S5/02284
摘要： A multimode fiber optical fiber transmission system includes an improved configuration for launching a single mode long wavelength transmission signal into existing multimode optical fiber networks. More specifically, the invention utilizes new single mode long wavelength VCSEL devices to realize a novel transmitter/transceiver for multimode fiber links where offset launch with controlled mode conditioning is achieved without the use of a mode conditioning patchcord, and in some embodiments, without the use of any collecting or focusing elements.
摘要翻译：多模光纤传输系统包括将单模长波发射信号发射到现有多模光纤网络中的改进配置。更具体地，本发明利用新的单模长波长VCSEL设备来实现用于多模光纤链路的新型发射机/收发器，其中在不使用模式调制跳频的情况下实现具有受控模式调节的偏移发射，并且在一些实施例中，不使用的任何收集或聚焦元素。

8. 发明授权

US07211045B2 Method and system for using ultrasound in cardiac diagnosis and therapy 有权
标题翻译：在心脏诊断和治疗中使用超声的方法和系统
公开(公告)号：US07211045B2
公开(公告)日：2007-05-01
申请号：US10620517
申请日：2003-07-16
申请人： Praveen Dala-Krishna , Charles Bryan Byrd , David Jenkins , Charles Lee Byrd
发明人： Praveen Dala-Krishna , Charles Bryan Byrd , David Jenkins , Charles Lee Byrd
IPC分类号： A61B8/06
CPC分类号： A61B8/0883 , A61B8/065 , A61B8/12 , A61B8/543
摘要： A method and system for estimating the volume of blood ejected from the left ventricle of the heart to a succeeding chamber/conduit, or vice-versa, while imaging the intersection of such structures is described. The process utilizes either the M-mode to estimate volume differences in a view of the ventricle over time or Doppler processing techniques to obtain flow profiles across intersections (e.g., valves), or blood vessels, which are then utilized to calculate output. This process can be combined with ECG guidance/triggering to measure/track changes in output from beat to beat, or during the course of an evaluation or therapeutic procedure. This process can be specifically used for the placement of permanent pacemaker electrodes.
摘要翻译：描述了在对这种结构的交叉进行成像时估计从心脏左心室向后续腔室/导管喷射的血液的体积或反之亦然的方法和系统。该过程利用M模式来估计随时间的心室视图中的体积差异或多普勒处理技术以获得跨越交叉点（例如，阀）或血管的流量分布，然后将其用于计算输出。该过程可以与ECG指导/触发相结合，以测量/跟踪从节拍到节拍的输出变化，或在评估或治疗过程中。该过程可以专门用于放置恒定起搏器电极。

9. 发明授权

US06969181B1 Fully recessed unit equipment luminaire 有权
标题翻译：全嵌入式单元设备灯具
公开(公告)号：US06969181B1
公开(公告)日：2005-11-29
申请号：US09851367
申请日：2001-05-08
申请人： Glenn Eric Bailey , Robert J. Riffel , David Jenkins
发明人： Glenn Eric Bailey , Robert J. Riffel , David Jenkins
IPC分类号： F21S2/00 , F21S8/02 , F21S9/02 , F21V7/00 , F21V11/02 , F21V14/04 , F21V15/01 , F21V17/00 , F21V17/16 , F21V21/04 , F21V21/30
CPC分类号： F21S9/022 , F21S2/00 , F21S8/02 , F21S8/024 , F21S8/026 , F21V7/0025 , F21V11/02 , F21V14/04 , F21V17/164 , F21V21/04 , F21V21/30
摘要： A fully recessed unit equipment luminaire for providing emergency lighting to a path of egress. The luminaire has batteries, a battery box, a housing, a charger/emergency switching circuit mounted on a chassis, lamps, reflector assemblies, and a cover. The luminaire may be configured for either wall or ceiling mounting with the use of wall or ceiling mount lenses, respectively. Reflector assemblies supporting the lamps are rotatably engaged by the cover. Each reflector assembly has a substantially semi-frustoconical shape and intersects the lamp's conical shaped beam of light to redirect the beam into a narrow, elongated pattern. The reflector assemblies may have a plurality of planar reflecting surfaces which approximate the semi-frustoconical shape.
摘要翻译：一个完全凹陷的单元设备灯具，用于向出口的路径提供应急照明。灯具具有电池，电池盒，外壳，安装在底盘上的充电器/紧急开关电路，灯，反射器组件和盖。灯具可以分别使用墙壁或天花板安装透镜来配置为墙壁或天花板安装。支撑灯的反射器组件由盖可旋转地接合。每个反射器组件具有基本上半截头圆锥形的形状并且与灯的锥形光束相交，以将光束重定向成窄的细长图案。反射器组件可以具有接近半截头圆锥形状的多个平面反射表面。

10. 发明授权

US06908434B1 Ultrasound imaging catheter isolation system with temperature sensor 有权
标题翻译：超声成像导管隔离系统带温度传感器
公开(公告)号：US06908434B1
公开(公告)日：2005-06-21
申请号：US10345806
申请日：2003-01-16
申请人： David Jenkins , Simcha Borovsky
发明人： David Jenkins , Simcha Borovsky
IPC分类号： A61B8/12 , A61B8/14
CPC分类号： A61B8/12
摘要： An ultrasonic imaging catheter is disclosed that includes a thermistor mounted on the catheter in the vicinity of the ultrasound transducer for monitoring the temperature in the vicinity thereof. The electrical signal from the thermistor can be used to control the output of the ultrasound transducer to thereby control the temperature of the same. In a further aspect of the invention, an isolation box is provided that is external to the ultrasound machine itself and is connected to the same by a cable. Ideally, the isolation box which houses a sufficient number of isolation transformers, is small, so it can be placed easily on or near the patient's bed.
摘要翻译：公开了一种超声成像导管，其包括安装在超声波换能器附近的导管上的热敏电阻，用于监测其附近的温度。来自热敏电阻的电信号可用于控制超声波换能器的输出，从而控制其温度。在本发明的另一方面，提供了一种在超声波机器本身外部并通过电缆与其连接的隔离盒。理想情况下，容纳足够数量的隔离变压器的隔离箱很小，因此可以方便地放置在患者床上或附近。

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