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1. 发明授权

US06641610B2 Valve designs for left ventricular conduits 失效
标题翻译：阀门设计用于左心室导管
公开(公告)号：US06641610B2
公开(公告)日：2003-11-04
申请号：US09368393
申请日：1999-08-04
申请人： Scott J. Wolf , Greg R. Furnish , Todd A. Hall , David Y. Phelps , Peter J. Wilk , Nancy C. Briefs , William Santamore , Daniel Burkhoff
发明人： Scott J. Wolf , Greg R. Furnish , Todd A. Hall , David Y. Phelps , Peter J. Wilk , Nancy C. Briefs , William Santamore , Daniel Burkhoff
IPC分类号： A61F206
CPC分类号： A61F2/94 , A61F2/06 , A61F2/2493 , A61F2/848 , A61F2/958 , A61F2002/821 , A61F2230/0067 , A61F2230/0078 , A61F2230/008 , A61M39/24
摘要： Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉狭窄或闭塞提供旁路。导管适于定位在心肌中以提供血液从冠状动脉血管流过冠状动脉的阻塞或狭窄位置的通道。导管具有定位在其中的单向阀，以防止血液从冠状动脉回流进心室。

2. 发明授权

US06261304B1 Delivery methods for left ventricular conduit 失效
公开(公告)号：US06261304B1
公开(公告)日：2001-07-17
申请号：US09368868
申请日：1999-08-04
申请人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps
发明人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps
IPC分类号： A61M2900
CPC分类号： A61M25/0147 , A61B2017/00247 , A61B2017/00252 , A61B2017/22071 , A61B2017/22095 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61F2/95 , A61F2/958 , A61M25/0152 , A61M25/0155 , A61M25/0194 , A61M25/10 , A61M25/1006 , A61M25/1011 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , A61M2025/1097 , A61M2210/125
摘要： Described herein are various methods and apparatuses for delivering stents or conduits and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.

3. 发明授权

US06196230B1 Stent delivery system and method of use 失效
标题翻译：支架输送系统及使用方法
公开(公告)号：US06196230B1
公开(公告)日：2001-03-06
申请号：US09150181
申请日：1998-09-10
申请人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps , Vincent Pompili
发明人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps , Vincent Pompili
IPC分类号： A61B1900
CPC分类号： A61F2/958 , A61B2017/00247 , A61B2017/00252 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61M25/10 , A61M25/1006 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , Y10S623/903
摘要： Described herein are various methods and apparatuses for delivering stents and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.
摘要翻译：这里描述了用于将支架和其他装置输送到患者的心肌中的各种方法和装置。一个优选的支架递送系统通过使输送导管通过冠状动脉阻塞或通过冠状静脉或通过在阻塞周围形成的通道或隧道周围的阻塞来推进进入心肌中的插入部位。在一个实施例中，一旦输送导管的远端与心肌相邻，则通过致动安装到导管的可扩展转向引导件，在导管中产生成角度的弯曲部，其与血管的壁配合以使导管转动。然后，导丝通过输送导管进入心肌。在另一个实施例中，尖端偏转拉线从输送导管的远端延伸，可以被致动以转向然后插入心肌。在另一个实施例中，面向插入部位的出口端设置在导管内或安装在导管上的球囊上，使得导丝可以被引导通过内腔并离开出口进入心肌。一旦导丝穿刺入心肌，就使用倒刺，气球或其他可致动部件来固定导丝，以将导丝固定到心肌。随后，使用推拉机构，支架和其他医疗装置可以在导丝上前进进入心肌。

4. 发明申请

US20080262602A1 Methods and conduits for flowing blood from a heart chamber to a blood vessel 有权
标题翻译：将血液从心脏腔室流动到血管的方法和管道
公开(公告)号：US20080262602A1
公开(公告)日：2008-10-23
申请号：US12149901
申请日：2008-05-09
申请人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
发明人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
IPC分类号： A61F2/24
CPC分类号： A61F2/82 , A61F2/2493 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/94 , A61F2/958 , A61F2/962 , A61M27/002 , A61M2210/125
摘要： Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉闭塞或狭窄提供旁路。导管是适于定位在心脏壁中的管，以在远离闭塞或狭窄的部位提供血液在心脏室和冠状动脉之间流动的通道。导管具有连接到其内腔的血管部分，其优选地包括位于其中的至少一个天然存在的单向阀。该阀阻止血液从冠状动脉回流进心室。

5. 发明授权

US06254564B1 Left ventricular conduit with blood vessel graft 有权
标题翻译：导管带有血管移植血管
公开(公告)号：US06254564B1
公开(公告)日：2001-07-03
申请号：US09369061
申请日：1999-08-04
申请人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
发明人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
IPC分类号： A61M500
CPC分类号： A61F2/82 , A61F2/2493 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/94 , A61F2/958 , A61F2/962 , A61M27/002 , A61M2210/125
摘要： Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉闭塞或狭窄提供旁路。导管是适于定位在心脏壁中的管，以在远离闭塞或狭窄的部位提供血液在心脏室和冠状动脉之间流动的通道。导管具有连接到其内腔的血管部分，其优选地包括位于其中的至少一个天然存在的单向阀。该阀阻止血液从冠状动脉回流进心室。

6. 发明授权

US07736327B2 Methods and conduits for flowing blood from a heart chamber to a blood vessel 有权
标题翻译：将血液从心脏腔室流动到血管的方法和管道
公开(公告)号：US07736327B2
公开(公告)日：2010-06-15
申请号：US12149901
申请日：2008-05-09
申请人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
发明人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
IPC分类号： A61M5/00 , A61B17/08 , A61F2/06 , A61F2/04
CPC分类号： A61F2/82 , A61F2/2493 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/94 , A61F2/958 , A61F2/962 , A61M27/002 , A61M2210/125
摘要： Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉闭塞或狭窄提供旁路。导管是适于定位在心脏壁中的管，以在远离闭塞或狭窄的部位提供血液在心脏室和冠状动脉之间流动的通道。导管具有连接到其内腔的血管部分，其优选地包括位于其中的至少一个天然存在的单向阀。该阀阻止血液从冠状动脉回流进心室。

7. 发明授权

US06881199B2 Left ventricular conduit with blood vessel graft 有权
标题翻译：左心室导管与血管移植
公开(公告)号：US06881199B2
公开(公告)日：2005-04-19
申请号：US09828794
申请日：2001-04-10
申请人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
发明人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
IPC分类号： A61B17/00 , A61F2/02 , A61F2/24 , A61F2/90 , A61F2/94 , A61M5/00 , A61B17/08 , A61F2/04 , A61F2/06
CPC分类号： A61F2/82 , A61F2/2493 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/94 , A61F2/958 , A61F2/962 , A61M27/002 , A61M2210/125
摘要： A method of flowing blood from a heart chamber to a coronary vessel includes providing a conduit with a first end and second end, providing the conduit within a heart wall such that the first end of the conduit is open towards the heart chamber and the second end is open towards the blood vessel, and during diastole, restricting a flow of blood from the coronary vessel to the heart chamber via the natural valve.
摘要翻译：将血液从心脏腔室流动到冠状动脉血管的方法包括提供具有第一端和第二端的导管，将导管提供在心脏壁内，使得导管的第一端朝向心室敞开，第二端向血管开放，并且在舒张期间，通过自然阀将血液从冠状血管限制到心室。

8. 发明授权

US06409751B1 Stent delivery system and method of use 失效
标题翻译：支架输送系统及使用方法
公开(公告)号：US06409751B1
公开(公告)日：2002-06-25
申请号：US09710884
申请日：2000-11-14
申请人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps , Vincent Pompili
发明人： Todd A. Hall , Greg R. Furnish , Simon M. Furnish , Scott J. Wolf , Peter J. Wilk , David Y. Phelps , Vincent Pompili
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61B2017/00247 , A61B2017/00252 , A61B2018/00392 , A61F2/2493 , A61F2/86 , A61M25/10 , A61M25/1006 , A61M2025/0096 , A61M2025/0197 , A61M2025/1095 , Y10S623/903
摘要： Described herein are various methods and apparatuses for delivering stents and other devices into the myocardium of a patient. One preferred stent delivery system provides access to the insertion site in the myocardium by advancing a delivery catheter through a blockage in a coronary artery, or around the blockage through a coronary vein or through a channel or tunnel formed around the blockage. In one embodiment, once the distal end of the delivery catheter is adjacent the myocardium, an angled bend is created in the catheter by actuating expandable steering guides mounted to the catheter which cooperate with the walls of the blood vessel to cause the catheter to turn. Then, a guidewire is advanced through the delivery catheter and into the myocardium. In another embodiment, a tip-deflecting pull wire extends from the distal end of the delivery catheter which may be actuated to turn towards and then inserted into the myocardium. In another embodiment, an exit port facing the insertion site is provided within the catheter or a balloon mounted on the catheter so that a guidewire may be directed through a lumen and out the exit port into the myocardium. Once the guidewire punctures into the myocardium, the guidewire is anchored using barbs, balloons or other actuatable members to secure the guidewire to the myocardium. Subsequently, using a push-pull mechanism, stents and other medical devices can be advanced over the guidewire into the myocardium.
摘要翻译：这里描述了用于将支架和其他装置输送到患者的心肌中的各种方法和装置。一个优选的支架递送系统通过使输送导管通过冠状动脉阻塞或通过冠状静脉或通过在阻塞周围形成的通道或隧道周围的阻塞来推进进入心肌中的插入部位。在一个实施例中，一旦输送导管的远端与心肌相邻，则通过致动安装到导管的可扩展转向引导件，在导管中产生成角度的弯曲部，其与血管的壁配合以使导管转动。然后，导丝通过输送导管进入心肌。在另一个实施例中，尖端偏转拉线从输送导管的远端延伸，可以被致动以转向然后插入心肌。在另一个实施例中，面向插入部位的出口端设置在导管内或安装在导管上的球囊上，使得导丝可以被引导通过内腔并离开出口进入心肌。一旦导丝穿刺入心肌，就使用倒刺，气球或其他可致动部件来固定导丝，以将导丝固定到心肌。随后，使用推拉机构，支架和其他医疗装置可以在导丝上前进进入心肌。

9. 发明授权

US08597226B2 Methods and conduits for flowing blood from a heart chamber to a blood vessel 有权
标题翻译：将血液从心脏腔室流动到血管的方法和管道
公开(公告)号：US08597226B2
公开(公告)日：2013-12-03
申请号：US13494589
申请日：2012-06-12
申请人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
发明人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
IPC分类号： A61M5/00 , A61B17/08 , A61F2/06 , A61F2/04
CPC分类号： A61F2/82 , A61F2/2493 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/94 , A61F2/958 , A61F2/962 , A61M27/002 , A61M2210/125
摘要： Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉闭塞或狭窄提供旁路。导管是适于定位在心脏壁中的管，以在远离闭塞或狭窄的部位提供血液在心脏室和冠状动脉之间流动的通道。导管具有连接到其内腔的血管部分，其优选地包括位于其中的至少一个天然存在的单向阀。该阀阻止血液从冠状动脉回流进心室。

10. 发明授权

US08216174B2 Methods and conduits for flowing blood from a heart chamber to a blood vessel 有权
标题翻译：将血液从心脏腔室流动到血管的方法和管道
公开(公告)号：US08216174B2
公开(公告)日：2012-07-10
申请号：US12771546
申请日：2010-04-30
申请人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
发明人： Peter J. Wilk , David Y. Phelps , Scott J. Wolf
IPC分类号： A61M5/00 , A61B17/08 , A61F2/06 , A61F2/04
CPC分类号： A61F2/82 , A61F2/2493 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/94 , A61F2/958 , A61F2/962 , A61M27/002 , A61M2210/125
摘要： Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.
摘要翻译：公开了一种导管，其围绕冠状动脉闭塞或狭窄提供旁路。导管是适于定位在心脏壁中的管，以在远离闭塞或狭窄的部位提供血液在心脏室和冠状动脉之间流动的通道。导管具有连接到其内腔的血管部分，其优选地包括位于其中的至少一个天然存在的单向阀。该阀阻止血液从冠状动脉回流进心室。

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