专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110188339A1 Rotationally Actuated Magnetic Bead Trap and Mixer 有权
标题翻译：旋转驱动磁珠和混合器
公开(公告)号：US20110188339A1
公开(公告)日：2011-08-04
申请号：US13015731
申请日：2011-01-28
申请人： Peter B. Howell, JR. , Richard Eitel , Joel P. Golden , Frances S. Ligler
发明人： Peter B. Howell, JR. , Richard Eitel , Joel P. Golden , Frances S. Ligler
IPC分类号： B01F13/08
CPC分类号： B01F13/0818 , B01F7/00908
摘要： A magnetic bead trap-and-mixer includes a channel having openings at opposing ends, and a rotor adjacent to the channel and comprising a permanent magnet, wherein the rotor is adapted to apply a magnetic field to the channel of sufficient strength to direct the movement of magnetic beads therein. In aspects, the channel is straight and/or has narrowed end. In further aspects, the rotor generates in the channel areas of areas of strong magnetic fields alternating with areas of very weak magnetic fields and the strong magnetic fields extend entirely across the channel.
摘要翻译：磁珠捕集器和混合器包括在相对端处具有开口的通道和与通道相邻并包括永磁体的转子，其中转子适于向通道施加足够强度的磁场以引导运动的磁珠。在方面，通道是直的和/或具有变窄的端。在另外的方面，转子在与非常弱的磁场的区域交替的强磁场的区域的通道区域中产生，并且强磁场完全延伸穿过通道。

2. 发明授权

US06192168B1 Reflectively coated optical waveguide and fluidics cell integration 有权
标题翻译：反光涂层光波导和流体电池集成
公开(公告)号：US06192168B1
公开(公告)日：2001-02-20
申请号：US09288957
申请日：1999-04-09
申请人： Mark J. Feldstein , Joel P. Golden , Frances S. Ligler , Chris A. Rowe
发明人： Mark J. Feldstein , Joel P. Golden , Frances S. Ligler , Chris A. Rowe
IPC分类号： G02B600
CPC分类号： G01N21/648 , G01N21/552 , G01N21/7703 , G01N33/54373 , G01N33/54393 , G01N2021/7709 , G01N2021/7776 , G01N2021/7786 , G01N2021/7793 , G01N2201/024 , G02B6/10 , G02B6/4206
摘要： A multimode waveguide device for assays includes a multimode waveguide with a patterned, reflective surface coating. The exposed portion or portions of the reflectively coated waveguide surface are for analyte recognition. A fluidics cell is attached to the waveguide so that the channel or channels of the fluidics cell match with the exposed portion or portions of the waveguide surface. The channel or channels direct one or more sample fluids over the exposed portion or portions of the waveguide surface. The reflective coating minimizes loss and scattering of excitation and fluorescence light during a fluorescence assay.
摘要翻译：用于测定的多模波导器件包括具有图案化的反射表面涂层的多模波导。反射涂覆的波导表面的暴露部分或部分用于分析物识别。流体池连接到波导，使得流体池的通道或通道与波导表面的暴露的部分或部分匹配。通道或通道将一个或多个样品流体引导到波导表面的暴露部分或部分上。反射涂层在荧光测定期间使激发和荧光的损耗和散射最小化。

3. 发明申请

US20110301049A1 Fluid Flow Contour Control Using Flow Resistance 审中-公开
标题翻译：使用流动阻力的流体流轮廓控制
公开(公告)号：US20110301049A1
公开(公告)日：2011-12-08
申请号：US12794275
申请日：2010-06-04
申请人： Joel P. Golden , Peter B. Howell, JR.
发明人： Joel P. Golden , Peter B. Howell, JR.
IPC分类号： C40B30/04 , C40B40/08
CPC分类号： B01L3/502746 , B01L3/502784 , B01L2200/0636 , B01L2300/0636 , B01L2300/0877 , B01L2400/086
摘要： A micro-fluidic device and a method of use are disclosed. The device includes a micro-channel with an inlet port at a first end and an outlet port at a second end. A first fluid, such as air or liquid or both, is disposed in the micro-channel. A focusing structure extends into the micro-channel, whereby when a pulse of a second fluid is introduced to the channel, the pulse advances adjacent sides of the micro-channel at a faster rate than would occur without the focusing structure.
摘要翻译：公开了微流体装置和使用方法。该装置包括具有在第一端处的入口端口和在第二端部处的出口端口的微通道。诸如空气或液体或两者的第一流体设置在微通道中。聚焦结构延伸到微通道中，由此当将第二流体的脉冲引入通道时，脉冲以比没有聚焦结构的情况更快的速度使微通道的相邻侧向前进。

4. 发明授权

US08577658B2 Numerical toolbox for design of fluidic components and systems 有权
标题翻译：用于流体组件和系统设计的数值工具箱
公开(公告)号：US08577658B2
公开(公告)日：2013-11-05
申请号：US11682068
申请日：2007-03-05
申请人： Peter B. Howell, Jr. , David Mott , Joel P. Golden
发明人： Peter B. Howell, Jr. , David Mott , Joel P. Golden
IPC分类号： G06G7/50 , G06G7/48 , G06F7/60 , G06F17/10
CPC分类号： G06F17/5018 , B01F5/061 , B01F13/0059 , B01F2005/0623 , B01F2005/0636 , B01J19/0093 , B01J2219/00889 , B01J2219/00995 , G06F2217/16
摘要： A computational “toolbox” can be used for the a priori design of optimized fluidic components. These components include a channel under low-Reynolds number, pressure-driven flow, with an arrangement of grooves cut into the top and/or bottom to generate a tailored cross-channel flow. An advection map for each feature (i.e., groove of a particular shape and orientation) predicts the lateral transport of fluid within the channel due to that feature. Applying the advection maps in sequence generates a representation of the outflow distribution for complex designs that combine one or more features. Therefore, the effect of the complex three-dimensional flow field can be predicted without solving the governing flow equations through the composite geometry, and the resulting distribution of fluids in the channel is used to evaluate how well a component performs a specified task. The toolbox is applied to determine optimal combinations of features for specified mixer sizes and mixing metrics.
摘要翻译：计算“工具箱”可用于优化流体组件的先验设计。这些部件包括低雷诺数下的通道，压力驱动流动，其中沟槽的排列切入顶部和/或底部以产生定制的横流通道。每个特征的对流图（即，特定形状和取向的凹槽）预测由于该特征而在通道内的流体的横向输送。顺序应用平流图生成组合一个或多个特征的复杂设计的流出分布表示。因此，可以预测复合三维流场的影响，而无需通过复合几何来解决控制流方程，并且使用通道中流体的最终分布来评估组件执行指定任务的程度。该工具箱用于确定特定混合器尺寸和混合度量的特征的最佳组合。

5. 发明申请

US20080221844A1 NUMERICAL TOOLBOX FOR DESIGN OF FLUIDIC COMPONENTS AND SYSTEMS 有权
标题翻译：流体组件和系统设计的数值工具箱
公开(公告)号：US20080221844A1
公开(公告)日：2008-09-11
申请号：US11682068
申请日：2007-03-05
申请人： Peter B. Howell , David Mott , Joel P. Golden
发明人： Peter B. Howell , David Mott , Joel P. Golden
IPC分类号： G06F17/10
CPC分类号： G06F17/5018 , B01F5/061 , B01F13/0059 , B01F2005/0623 , B01F2005/0636 , B01J19/0093 , B01J2219/00889 , B01J2219/00995 , G06F2217/16
摘要： A described exemplary embodiment of the present invention includes a computational “toolbox” for the a priori design of optimized fluidic components. These components consist of a channel under low-Reynolds number, pressure-driven flow, with an arrangement of grooves cut into the top and/or bottom to generate a tailored cross-channel flow. An advection map for each feature (i.e., groove of a particular shape and orientation) predicts the lateral transport of fluid within the channel due to that feature. We show that applying these maps in sequence generates an excellent representation of the outflow distribution for complex designs that combine these basic features. The effect of the complex three-dimensional flow field can therefore be predicted without solving the governing flow equations through the composite geometry, and the resulting distribution of fluids in the channel is used to evaluate how well a component performs a specified task. The generation and use of advection maps is described, and the toolbox is applied to determine optimal combinations of features for specified mixer sizes and mixing metrics.
摘要翻译：本发明的描述的示例性实施例包括用于优化的流体组件的先验设计的计算“工具箱”。这些部件由低雷诺数，压力驱动流动下的通道组成，并且沟槽的排列切入顶部和/或底部以产生定制的横流通道。每个特征的对流图（即，特定形状和取向的凹槽）预测由于该特征而在通道内的流体的横向输送。我们表明，按顺序生成这些地图可以显示出组合这些基本特征的复杂设计的流出分布的极好表现。因此，可以预测复杂三维流场的影响，而无需通过复合几何来解决控制流程方程，并且使用通道中流体的最终分布来评估组件执行特定任务的程度。描述对流图的生成和使用，并且应用该工具箱来确定用于指定的混合器大小和混合度量的特征的最佳组合。

6. 发明授权

US5827748A Chemical sensor using two-dimensional lens array 失效
标题翻译：化学传感器采用二维透镜阵列
公开(公告)号：US5827748A
公开(公告)日：1998-10-27
申请号：US787720
申请日：1997-01-24
申请人： Joel P. Golden
发明人： Joel P. Golden
IPC分类号： G01N33/543 , G01N33/552
CPC分类号： G01N33/54373 , Y10S435/968 , Y10S435/97 , Y10S435/973 , Y10S436/806 , Y10S436/807 , Y10S436/809
摘要： A chemical sensor includes a patterned layer having discrete sections, a -dimensional detector array, and a two-dimensional lens array that focuses an optical signal from the patterned layer onto the two dimensional detector array. Typically, the two-dimensional detector array is a charge-coupled device array and the lens array is a graded index of refraction lens array. The chemical sensor maintains good resolution throughout its field of view.
摘要翻译：化学传感器包括具有离散部分的图案化层，二维检测器阵列和将来自图案化层的光学信号聚焦到二维检测器阵列上的二维透镜阵列。通常，二维检测器阵列是电荷耦合器件阵列，透镜阵列是折射透镜阵列的渐变折射率。化学传感器在其整个视野内保持良好的分辨率。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式