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    • 6. 发明授权
    • Process for adding pharmaceutically active compounds to substrates
    • 向基质中加入药物活性化合物的方法
    • US06316019B1
    • 2001-11-13
    • US09449132
    • 1999-11-24
    • Ching-Yun Morris Yang
    • Ching-Yun Morris Yang
    • A61F1302
    • A61L15/46A61K9/0036A61K47/10A61L15/20A61L2300/216A61L2300/22
    • The present invention relates to a low temperature process for adding pharmaceutically active compounds to substrates. The substrates are preferably those used in the manufacture of disposable absorbent articles, or are the articles themselves. The pharmaceutically active compound is selected from the group consisting of: monoesters of a polyhydric aliphatic alcohol and a fatty acid containing from eight to eighteen carbon atoms and wherein said monoester has at least one hydroxyl group associated with its aliphatic alcohol residue; diesters of a polyhydric aliphatic alcohol and a fatty acid containing from eight to eighteen carbon atoms and wherein said diester has at least one hydroxyl group associated with its aliphatic alcohol residue; and mixtures of said monoesters and diesters.
    • 本发明涉及向基质中加入药物活性化合物的低温方法。 基材优选用于一次性吸收制品的制造中,或者是制品本身。 药物活性化合物选自:多元脂肪醇的单酯和含有8至18个碳原子的脂肪酸,其中所述单酯具有与其脂族醇残基相关的至少一个羟基; 多元脂肪醇的二酯和含有8至18个碳原子的脂肪酸,并且其中所述二酯具有与其脂族醇残基相关的至少一个羟基; 以及所述单酯和二酯的混合物。