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    • 1. 发明申请
    • Method of Calibrating a System for Measuring the Concentration of Substances in Body and an Apparatus for Exercising the Method
    • 校准体内物质浓度测定系统的方法及其运用方法
    • US20080312859A1
    • 2008-12-18
    • US11661866
    • 2005-09-05
    • Ole SkyggebjergArne Stjernholm MadsenMichael Gerstenberg
    • Ole SkyggebjergArne Stjernholm MadsenMichael Gerstenberg
    • G06F19/00G01N33/48
    • A61B5/1495A61B5/14532A61B2562/0295
    • This invention relates to procedures for the calibration of systems for continuously measuring the concentration of substances in a body fluid. The system comprises first and second sensors adapted for subcutaneous insertion and an electronic calculator unit adapted for measuring signals from the two sensors. The system is calibrated following the steps of: a) introducing the first sensor subcutaneously, b) calibrating the first sensor, c) obtaining sensor data S1(t) provided by the first sensor, d) introducing the second sensor subcutaneously, e) obtaining sensor data S2(t) provided by the second sensor, f) determining the rate of change over time δR(t)/δt, R(t) being a signal which correlates to sensor data S2(t) over time, and g) performing a calibration of the second sensor when δR(t)/δt is less than a predetermined value, said calibration of the second sensor being performed using sensor data S1(t) obtained by the first sensor.
    • 本发明涉及用于校准连续测量体液中物质浓度的系统的方法。 该系统包括适于皮下插入的第一和第二传感器以及适于测量来自两个传感器的信号的电子计算器单元。 按照以下步骤校准系统:a)皮下引入第一传感器,b)校准第一传感器,c)获得由第一传感器提供的传感器数据S1(t),d)皮下引入第二传感器,e)获得 由第二传感器提供的传感器数据S2(t),f)确定随时间的变化率ΔR(t)/ deltat,R(t)是与传感器数据S2(t)随时间相关联的信号,g) 当deltaR(t)/ deltat小于预定值时,执行第二传感器的校准,使用由第一传感器获得的传感器数据S1(t)来执行第二传感器的校准。