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    • 6. 发明申请
    • MULTI-CULTURE BIOREACTOR SYSTEM
    • 多文化生物反应器系统
    • US20110207175A1
    • 2011-08-25
    • US13122933
    • 2009-10-02
    • Marwan El-SabbanSteen Sindet-Pedersen
    • Marwan El-SabbanSteen Sindet-Pedersen
    • C12P21/00
    • C12M35/08C12M23/34C12M23/44C12M29/04
    • There is provided co-culture bioreactor systems that can maintain stem cells and differentiated cell types in physically isolated environments but can allow biochemical communication between these cells. For instance, a co-culture bioreactor system of the present invention can include a first culture chamber that defines a first inlet and a first outlet such that fluid can flow through the culture chamber. The system can also include a second culture chamber defining a second inlet and a second outlet allowing a second fluid flow through this second chamber. The system can also include a semi-permeable membrane. The semi-permeable membrane can be located between the first culture chamber and the second culture chamber.
    • 提供共培养生物反应器系统,其可以在物理隔离的环境中维持干细胞和分化的细胞类型,但可以允许这些细胞之间的生物化学通信。 例如,本发明的共培养生物反应器系统可以包括限定第一入口和第一出口的第一培养室,使得流体可以流过培养室。 该系统还可以包括限定第二入口的第二培养室和允许第二流体流过该第二室的第二出口。 该系统还可以包括半透膜。 半透膜可位于第一培养室和第二培养室之间。