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1. 发明授权

US07276251B2 Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid 有权
标题翻译：包封在透明质酸微粒中的药物的缓释组合物
公开(公告)号：US07276251B2
公开(公告)日：2007-10-02
申请号：US10205954
申请日：2002-07-26
申请人： Myung-Jin Kim , Sun-Jin Kim , Oh-Ryong Kwon
发明人： Myung-Jin Kim , Sun-Jin Kim , Oh-Ryong Kwon
IPC分类号： A61K9/19 , A61K9/22
CPC分类号： A61K9/1652 , Y10S514/951
摘要： A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased in said microparticles, wherein the average size of said microparticles ranges from 0.1 to 40 μm.
摘要翻译：一种基本上由具有高分子量的透明质酸微粒或其无机盐组成的缓释药物组合物和包在所述微粒中的蛋白质或肽药物，其中所述微粒的平均尺寸为0.1-40μm。

2. 发明申请

US20080063727A1 Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid 审中-公开
标题翻译：包封在透明质酸微粒中的药物的缓释组合物
公开(公告)号：US20080063727A1
公开(公告)日：2008-03-13
申请号：US11979148
申请日：2007-10-31
申请人： Myung-Jin Kim , Sun-Jin Kim , Oh-Ryong Kwon
发明人： Myung-Jin Kim , Sun-Jin Kim , Oh-Ryong Kwon
IPC分类号： A61K38/22 , A61K38/02 , A61K38/27 , A61K38/30 , A61K9/14 , A61K38/49 , A61K38/28 , A61K38/21
CPC分类号： A61K9/14 , A61K9/0024 , A61K9/1652 , A61K38/00
摘要： A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased in said microparticles, wherein the average size of said microparticles ranges from 0.1 to 40 μm.
摘要翻译：一种基本上由具有高分子量的透明质酸微粒或其无机盐组成的缓释药物组合物和包在所述微粒中的蛋白质或肽药物，其中所述微粒的平均尺寸为0.1-40μm。

3. 发明申请

US20050100605A1 Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid 审中-公开
标题翻译：包封在透明质酸微粒中的药物的缓释组合物
公开(公告)号：US20050100605A1
公开(公告)日：2005-05-12
申请号：US11013354
申请日：2004-12-17
申请人： Myung-Jin Kim , Sun-Jin Kim , Oh-Ryong Kwon
发明人： Myung-Jin Kim , Sun-Jin Kim , Oh-Ryong Kwon
IPC分类号： A61K9/16 , A61K38/48 , A61K39/395 , A61K9/22 , A61K9/14 , A61K38/19 , A61K38/22 , A61K38/21
CPC分类号： A61K9/1652 , Y10S514/951
摘要： A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased in said microparticles, wherein the average size of said microparticles ranges from 0.1 to 40 μm.
摘要翻译：一种基本上由具有高分子量的透明质酸微粒或其无机盐组成的缓释药物组合物和包在所述微粒中的蛋白质或肽药物，其中所述微粒的平均尺寸为0.1-40μm。

4. 发明授权

US07785625B2 Lipophilic-coated microparticle containing a protein drug and formulation comprising same 有权
标题翻译：含有蛋白质药物的亲油性包衣微粒和包含其的制剂
公开(公告)号：US07785625B2
公开(公告)日：2010-08-31
申请号：US11024362
申请日：2004-12-28
申请人： Myung-Jin Kim , Sun-Jin Kim , Kyu-Chan Kwon , Joon Kim
发明人： Myung-Jin Kim , Sun-Jin Kim , Kyu-Chan Kwon , Joon Kim
IPC分类号： A61K9/19 , A61K9/22
CPC分类号： A61K9/167 , A61K9/1617 , A61K9/1652 , C08L5/08 , C08L2666/02
摘要： A solid lipophilic microparticle having an average particle size ranging from 0.1 to 200 μm, comprising a lipophilic substance, hyaluronic acid or an inorganic salt thereof and an active ingredient selected from the group consisting of a protein or peptide drug, retains the full activity of the active ingredient, and when formulated in the form of an oil dispersion or oil-in-water emulsion, it releases in an in vivo environment the active ingredient in a controlled manner over a long period.
摘要翻译：平均粒度为0.1〜200μm的固体亲脂性微粒，其包含亲脂性物质，透明质酸或其无机盐，以及选自蛋白质或肽类药物的活性成分，保留了全部活性活性成分，当以油分散体或水包油乳剂的形式配制时，其在长时间内以有控制的方式在体内环境中释放活性成分。

5. 发明申请

US20050158392A1 Lipophilic-coated microparticle containing a protein drug and formulation comprising same 有权
标题翻译：含有蛋白质药物的亲油性包衣微粒和包含其的制剂
公开(公告)号：US20050158392A1
公开(公告)日：2005-07-21
申请号：US11024362
申请日：2004-12-28
申请人： Myung-Jin Kim , Sun-Jin Kim , Kyu-Chan Kwon , Joon Kim
发明人： Myung-Jin Kim , Sun-Jin Kim , Kyu-Chan Kwon , Joon Kim
IPC分类号： A61K9/16 , C08L5/08 , A61K38/48 , A61K9/14 , A61K31/728 , A61K38/18 , A61K38/22
CPC分类号： A61K9/167 , A61K9/1617 , A61K9/1652 , C08L5/08 , C08L2666/02
摘要： A solid lipophilic microparticle having an average particle size ranging from 0.1 to 200 μm, comprising a lipophilic substance, hyaluronic acid or an inorganic salt thereof and an active ingredient selected from the group consisting of a protein or peptide drug, retains the full activity of the active ingredient, and when formulated in the form of an oil dispersion or oil-in-water emulsion, it releases in an in vivo environment the active ingredient in a controlled manner over a long period.
摘要翻译：平均粒度为0.1〜200μm的固体亲脂性微粒，其包含亲脂性物质，透明质酸或其无机盐，以及选自蛋白质或肽类药物的活性成分，保留了全部活性活性成分，当以油分散体或水包油乳剂的形式配制时，其在长时间内以有控制的方式在体内环境中释放活性成分。

6. 发明授权

US09388377B2 Regenerative cell extraction unit and regenerative cell extraction system 有权
标题翻译：再生细胞提取单元和再生细胞提取系统
公开(公告)号：US09388377B2
公开(公告)日：2016-07-12
申请号：US13504586
申请日：2010-10-25
申请人： Byung-Rok Do , Jung-Kyu Lee , Ji-Hyang Kim , Sung-Guu Kang , Seung-Hoon Pak , Myung-Jin Kim , Kyu-Chul Shin , Chul-Geun Kim , Yung-Dal Yoon
发明人： Byung-Rok Do , Jung-Kyu Lee , Ji-Hyang Kim , Sung-Guu Kang , Seung-Hoon Pak , Myung-Jin Kim , Kyu-Chul Shin , Chul-Geun Kim , Yung-Dal Yoon
IPC分类号： B04B5/04 , C12M1/00
CPC分类号： C12M47/04 , B04B5/0442 , B04B11/02 , C12M45/05
摘要： Provided is a regenerative cell extraction system. The regenerative cell extraction system includes: a regenerative cell separation unit which separates fat tissue; and a regenerative cell extraction unit. The regenerative cell separation unit includes: a sub container which is rotated by a torque applied from an external source and includes a space in which fat tissue is housed; a hollow main pipe which is inserted into the sub container; and a pump which is connected to the main pipe. In addition, the regenerative cell extraction unit receives a regenerative cell-containing substance, which is obtained after the fat tissue is centrifuged by the regenerative cell separation unit, from the regenerative cell separation unit, and extracts regenerative cells from the substance by centrifuging the substance. The regenerative cell extraction unit includes: a main container which is rotated by a torque applied from an external source; a hollow first discharge pipe which is inserted into the main container; and a suction device which is connected to the first discharge pipe; and a plurality of protruding housing portions which bulge outwards along a radius direction with respect to a center of rotation of the main container to accommodate relatively heavy components among components separated from the substance.
摘要翻译：提供一种再生细胞提取系统。再生细胞提取系统包括：再生细胞分离单元，其分离脂肪组织; 和再生细胞提取单元。再生细胞分离单元包括：副容器，其由外部源施加的扭矩旋转，并且包括容纳脂肪组织的空间; 插入子容器中的中空主管; 以及与主管连接的泵。此外，再生细胞提取单元接收在再生细胞分离单元将脂肪组织离心后获得的再生细胞含有物质从再生细胞分离单元接收，并通过离心物质从物质中提取再生细胞。再生细胞提取单元包括：通过从外部源施加的转矩旋转的主容器; 插入主容器的中空的第一排出管; 以及连接到第一排出管的抽吸装置; 以及多个突出的壳体部分，其相对于主容器的旋转中心沿径向向外凸出，以容纳与物质分离的部件中相对较重的部件。

7. 发明授权

US07782120B2 Internal voltage generating circuit 失效
标题翻译：内部电压发生电路
公开(公告)号：US07782120B2
公开(公告)日：2010-08-24
申请号：US12051748
申请日：2008-03-19
申请人： Myung-Jin Kim , Dong-Hwee Kim
发明人： Myung-Jin Kim , Dong-Hwee Kim
IPC分类号： G05F3/02
CPC分类号： G11C29/12 , G11C5/145 , G11C29/12005
摘要： Disclosed is an internal voltage generating circuit that pumps charge to generate an internal driving voltage. The internal voltage generating circuit includes: a first oscillation signal generating unit that provides a first oscillation signal in response to a detected internal voltage and a predetermined test mode signal; a second oscillation signal generating unit that divides an external clock to provide a second oscillation signal having a variable oscillation period; and a switching unit that selects the first oscillation signal or the second oscillation signal in response to the predetermined test mode signal and provides the selected signal as a pumping period signal.
摘要翻译：公开了一种内部电压产生电路，其泵送电荷以产生内部驱动电压。内部电压产生电路包括：第一振荡信号产生单元，响应于检测到的内部电压和预定的测试模式信号而提供第一振荡信号; 第二振荡信号产生单元，其分割外部时钟以提供具有可变振荡周期的第二振荡信号; 以及切换单元，其响应于预定测试模式信号选择第一振荡信号或第二振荡信号，并将所选择的信号提供为泵浦周期信号。

8. 发明授权

US07573318B2 Internal voltage generating circuit 有权
标题翻译：内部电压发生电路
公开(公告)号：US07573318B2
公开(公告)日：2009-08-11
申请号：US11826501
申请日：2007-07-16
申请人： Myung-Jin Kim
发明人： Myung-Jin Kim
IPC分类号： G05F1/575 , H03B1/00
CPC分类号： H02M3/07
摘要： An internal voltage generating circuit includes a first detector that compares an internal voltage and a first reference voltage to output a first detection signal. A second detector compares a supply voltage and a second reference voltage to output a second detection signal. A loop selection oscillator performs an oscillation operation in response to the first detection signal, selects a first loop or a second loop for performing the oscillation operation in response to the second detection signal, and outputs an oscillation signal. A charge pump performs a pumping operation according to the output of the loop selection oscillator and generates the internal voltage.
摘要翻译：内部电压产生电路包括第一检测器，其比较内部电压和第一参考电压以输出第一检测信号。第二检测器比较电源电压和第二参考电压以输出第二检测信号。环路选择振荡器响应于第一检测信号执行振荡操作，响应于第二检测信号选择用于执行振荡操作的第一回路或第二回路，并输出振荡信号。电荷泵根据环路选择振荡器的输出进行泵浦操作，并产生内部电压。

9. 发明申请

US20090116303A1 Semiconductor memory device 失效
标题翻译：半导体存储器件
公开(公告)号：US20090116303A1
公开(公告)日：2009-05-07
申请号：US12217048
申请日：2008-06-30
申请人： Myung-Jin Kim
发明人： Myung-Jin Kim
IPC分类号： G11C7/00 , G11C8/00 , G11C5/14
CPC分类号： G11C11/4074 , G11C5/14
摘要： A semiconductor memory device can generate an under_drive voltage that maintains a predetermined level stably even in case of a change in the operation mode of the semiconductor memory device or the level of an external power supply voltage. The semiconductor memory device, which includes an external power supply voltage detector configured to detect a level of an external power supply voltage to generate the external voltage detection signal, an under_drive voltage detector configured to detect a voltage level of an under_drive voltage to generate the under_drive voltage detection signal, and an under_drive voltage generator configured to generate the under_drive voltage in response to the under_drive voltage detection signal with a variable driving force in response to the external voltage detection signal.
摘要翻译：半导体存储器件即使在半导体存储器件的操作模式改变或者外部电源电压的电平变化的情况下也能够产生保持预定电平的欠驱动电压。该半导体存储器件包括：外部电源电压检测器，被配置为检测外部电源电压的电平以产生外部电压检测信号;欠驱动电压检测器，被配置为检测欠驱动电压的电压电平以产生欠驱动电压检测信号和欠驱动电压发生器，其被配置为响应于外部电压检测信号以可变驱动力响应于欠驱动电压检测信号而产生欠驱动电压。

10. 发明申请

US20120214659A1 REGENERATIVE CELL EXTRACTION UNIT AND REGENERATIVE CELL EXTRACTION SYSTEM 有权
标题翻译：再生细胞提取单元和再生细胞提取系统
公开(公告)号：US20120214659A1
公开(公告)日：2012-08-23
申请号：US13504586
申请日：2010-10-25
申请人： Byung-Rok Do , Jung-Kyu Lee , Ji-Hyang Kim , Sung-Guu Kang , Seung-Hoon Pak , Myung-Jin Kim , Kyu-Chul Shin , Chul-Geun Kim , Yung-Dal Yoon
发明人： Byung-Rok Do , Jung-Kyu Lee , Ji-Hyang Kim , Sung-Guu Kang , Seung-Hoon Pak , Myung-Jin Kim , Kyu-Chul Shin , Chul-Geun Kim , Yung-Dal Yoon
IPC分类号： B04B7/00
CPC分类号： C12M47/04 , B04B5/0442 , B04B11/02 , C12M45/05
摘要： Provided is a regenerative cell extraction system. The regenerative cell extraction system includes: a regenerative cell separation unit which separates fat tissue; and a regenerative cell extraction unit. The regenerative cell separation unit includes: a sub container which is rotated by a torque applied from an external source and includes a space in which fat tissue is housed; a hollow main pipe which is inserted into the sub container; and a pump which is connected to the main pipe. In addition, the regenerative cell extraction unit receives a regenerative cell-containing substance, which is obtained after the fat tissue is centrifuged by the regenerative cell separation unit, from the regenerative cell separation unit, and extracts regenerative cells from the substance by centrifuging the substance. The regenerative cell extraction unit includes: a main container which is rotated by a torque applied from an external source; a hollow first discharge pipe which is inserted into the main container; and a suction device which is connected to the first discharge pipe; and a plurality of protruding housing portions which bulge outwards along a radius direction with respect to a center of rotation of the main container to accommodate relatively heavy components among components separated from the substance.
摘要翻译：提供一种再生细胞提取系统。再生细胞提取系统包括：再生细胞分离单元，其分离脂肪组织; 和再生细胞提取单元。再生细胞分离单元包括：副容器，其由外部源施加的扭矩旋转，并且包括容纳脂肪组织的空间; 插入子容器中的中空主管; 以及与主管连接的泵。此外，再生细胞提取单元接收在再生细胞分离单元将脂肪组织离心后获得的再生细胞含有物质从再生细胞分离单元接收，并通过离心物质从物质中提取再生细胞。再生细胞提取单元包括：通过从外部源施加的转矩旋转的主容器; 插入主容器的中空的第一排出管; 以及连接到第一排出管的抽吸装置; 以及多个突出的壳体部分，其相对于主容器的旋转中心沿径向向外凸出，以容纳与物质分离的部件中相对较重的部件。

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