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    • 1. 发明授权
    • Polyamine derivatives
    • 多胺衍生物
    • US08779195B2
    • 2014-07-15
    • US12514540
    • 2007-11-12
    • Muneharu MiyakeTadashi KusamaTakashi Masuko
    • Muneharu MiyakeTadashi KusamaTakashi Masuko
    • C07C303/00C07C307/00C07C309/00C07C311/00
    • C07C311/18C07C311/05
    • A compound having the general formula (I) or a pharmacologically acceptable salt thereof: X—NH—Y—NH—R1  (I) [wherein X represents R2—SO2— in which R2 represents an optionally substituted lower alkyl group or phenyl group; Y represents a group selected from the group consisting of —R3—NH—R4—, —R5—NH—R6—NH—R7—, —R8—NH—R9—NH—R10—NH—R11—and —R12—NH—R13—NH—R14—NH—R15— in which R3 to R15 each independently represent a C3 to C5 alkylene group; and R1 represents hydrogen or an optionally substituted lower alkyl group, with the proviso that the case where X represents a tosyl group, Y represents —(CH2)3—NH—(CH2)4—NH—(CH2)3—and R1 represents hydrogen is excepted].
    • 具有通式(I)的化合物或其药学上可接受的盐:X-NH-Y-NH-R1(I)[其中X表示R2-SO2-,其中R2表示任选取代的低级烷基或苯基; Y表示选自-R 3 -NH-R 4 - ,-R 5-NH-R 6 -NH-R 7 - , - R 8 -NH-R 9 -NH-R 10 -NH-R 11 - 和-R 12-NH -R13-NH-R14-NH-R15-,其中R3至R15各自独立地表示C3至C5亚烷基; 并且R 1表示氢或任选取代的低级烷基,条件是X表示甲苯磺酰基,Y表示 - (CH 2)3 -NH-(CH 2)4 -NH-(CH 2)3 - 并且R 1表示 氢除外]。
    • 2. 发明申请
    • NOVEL POLYAMINE DERIVATIVES
    • 新型聚氨酯衍生物
    • US20100063322A1
    • 2010-03-11
    • US12514540
    • 2007-11-12
    • Muneharu MiyakeTadashi KusamaTakashi Masuko
    • Muneharu MiyakeTadashi KusamaTakashi Masuko
    • C07C311/16C07C311/03
    • C07C311/18C07C311/05
    • A compound having the general formula (I) or a pharmacologically acceptable salt thereof: X—NH—Y—NH—R1  (I) [wherein X represents R2—SO2— in which R2 represents an optionally substituted lower alkyl group or phenyl group; Y represents a group selected from the group consisting of —R3—NH—R4—, —R5—NH—R6—NH—R7—, —R8—NH—R9—NH—R10—NH—R11— and —R12—NH—R13—NH—R14—NH—R15— in which R3 to R15 each independently represent a C3 to C5 alkylene group; and R1 represents hydrogen or an optionally substituted lower alkyl group, with the proviso that the case where X represents a tosyl group, Y represents —(CH2)3—NH—(CH2)4—NH—(CH2)3— and R1 represents hydrogen is excepted].
    • 具有通式(I)的化合物或其药学上可接受的盐:X-NH-Y-NH-R1(I)[其中X表示R2-SO2-,其中R2表示任选取代的低级烷基或苯基; Y表示选自-R 3 -NH-R 4 - ,-R 5-NH-R 6 -NH-R 7 - , - R 8 -NH-R 9 -NH-R 10 -NH-R 11 - 和-R 12-NH -R13-NH-R14-NH-R15-,其中R3至R15各自独立地表示C3至C5亚烷基; 并且R 1表示氢或任选取代的低级烷基,条件是其中X表示甲苯磺酰基,Y表示 - (CH2)3-NH-(CH2)4-NH-(CH2)3-,R1表示 氢除外]。
    • 10. 发明申请
    • Thermostat for two-system cooling device
    • 双系统冷却装置恒温器
    • US20050001044A1
    • 2005-01-06
    • US10494047
    • 2003-06-18
    • Takashi MasukoAkira MoriToru Yoshihara
    • Takashi MasukoAkira MoriToru Yoshihara
    • F01P7/16F16K31/68G05D23/13G05D23/02
    • F16K11/02F01P7/16F01P2003/027F01P2037/02G05D23/134
    • A thermostat independently controlling cooling water passages of two circuits, including a first valve body having first and second passages in constant communication. A third passage is selectively connected to those passages. Communication of the third passage is disconnected when the cooling water temperature is below a prescribed temperature, and the valve is opened when the cooling water temperature is equal to or higher than the prescribed temperature. A second valve body, having fourth and fifth passages selectively in communication, closes the valve to disconnect those passages when the cooling water temperature is below the prescribed temperature, and opens the valve by operating the first valve body to link the passages when the cooling water temperature is equal to or higher than the prescribed temperature. A tubular sleeve prevents first and second control chambers, respectively including the first and second valve bodies, from communicating with each other.
    • 一种独立控制两个电路的冷却水通道的恒温器,包括具有恒定连通的第一和第二通道的第一阀体。 选择性地连接到第三通道。 当冷却水温度低于规定温度时,第三通道的通信断开,当冷却水温度等于或高于规定温度时,阀门打开。 具有选择性连通的第四和第五通道的第二阀体在冷却水温度低于规定温度时关闭阀门以断开这些通道,并且当冷却水通过操作第一阀体连接通道而打开阀门 温度等于或高于规定温度。 管状套筒防止分别包括第一和第二阀体的第一和第二控制室彼此连通。