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1. 发明授权

US5675031A 4-hydroxy-2-cyclopentenone derivatives and anticancer agent and bone formation accelerator containing the same 失效
标题翻译： 4-羟基-2-环戊烯酮衍生物和抗癌剂及含有它们的骨形成加速剂
公开(公告)号：US5675031A
公开(公告)日：1997-10-07
申请号：US397176
申请日：1995-03-08
申请人： Minoru Furuya , Satoshi Sugiura , Atsuo Hazato
发明人： Minoru Furuya , Satoshi Sugiura , Atsuo Hazato
IPC分类号： C07C45/67 , C07C49/707 , C07C49/723 , C07C49/743 , C07C49/747 , C07C49/753 , C07C69/007 , C07C69/738 , C07C69/76 , C07C69/96 , C07C205/45 , C07C225/22 , C07C405/00 , C07D213/50 , C07D277/16 , C07D309/12 , C07D333/22 , C07F7/18 , C07H13/04 , C07H13/06
CPC分类号： C07H13/04 , C07C205/45 , C07C225/22 , C07C405/00 , C07C45/673 , C07C49/707 , C07C49/723 , C07C49/743 , C07C49/747 , C07C49/753 , C07C69/007 , C07C69/738 , C07C69/76 , C07C69/96 , C07D213/50 , C07D277/16 , C07D309/12 , C07D333/22 , C07F7/1852 , C07F7/1856 , C07H13/06 , C07C2101/10 , C07C2101/14
摘要： Specific optically active 4- hydroxy-2-cyclopentenone derivatives and mixtures thereof having the formula (I): ##STR1## and an anticancer-agent and a bone formation accelerator containing the same as effective active ingredients.
摘要翻译： PCT No.PCT / JP93 / 01266 Sec。 371日期：1995年3月8日 102（e）1995年3月8日PCT PCT 1993年9月7日PCT公布。第WO94 / 05619号公报日期：1994年3月17日具有式（I）的特定光学活性4-羟基-2-环戊烯酮衍生物及其混合物：（I）和抗癌剂和含有与有效活性成分相同的骨形成加速剂。

2. 发明授权

US5116869A 2-substituted-2-cyclopentenones 失效
标题翻译： 2-取代的2-环丙基
公开(公告)号：US5116869A
公开(公告)日：1992-05-26
申请号：US759785
申请日：1991-09-03
申请人： Satoshi Sugiura , Atsuo Hazato , Toru Minoshima , Yoshinori Kato , Yasuko Koshihara , Seizi Kurozumi
发明人： Satoshi Sugiura , Atsuo Hazato , Toru Minoshima , Yoshinori Kato , Yasuko Koshihara , Seizi Kurozumi
IPC分类号： C07C317/24 , C07C323/22 , C07C405/00 , C07D303/32 , C07D303/40
CPC分类号： C07C317/24 , C07C323/22 , C07C405/00 , C07C405/0033 , C07D303/32 , C07D303/40 , C07C2101/10
摘要： 2-Substituted-2-cyclopentenones represented by the formula (I): ##STR1## wherein A is a hydroxyl group or ##STR2## and B is a hydrogen atom or A and B are bonded together to form one bonding arm;R.sup.1 represents a substituted or unsubstituted hydrocarbon group having 1 to 10 carbon atoms;R.sup.2 represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 10 carbon atoms;R.sup.3 represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 10 carbon atoms; wherein,when R.sup.3 is a single bond bonded to the cyclopentene skeleton, X represents a hydrogen atom, a hydroxyl group or a protected hydroxyl group; andwhen R.sup.3 is a double bond bonded to the pentene skeleton, X represents a bonding arm constituting a part of said double bond; andm and n independently represent 0, 1 or 2.

3. 发明授权

US5216183A Cyclopentanone/cyclopentenone derivative 失效
标题翻译：环戊酮/环戊烯酮衍生物
公开(公告)号：US5216183A
公开(公告)日：1993-06-01
申请号：US836562
申请日：1992-02-18
申请人： Satoshi Sugiura , Toru Minoshima , Atsuo Hazato , Yoshinori Kato
发明人： Satoshi Sugiura , Toru Minoshima , Atsuo Hazato , Yoshinori Kato
IPC分类号： C07C45/72 , C07C49/707 , C07C49/753 , C07C317/24 , C07C317/46 , C07C323/22 , C07C323/61 , C07C405/00 , C07D213/70 , C07D233/84 , C07D239/38 , C07D257/04 , C07D263/58 , C07D277/16 , C07D277/74 , C07D303/32 , C07D303/40 , C07D307/38 , C07D307/46 , C07D405/12 , C07D473/38 , C07F7/18 , C07H13/04
CPC分类号： C07D213/70 , C07C317/24 , C07C317/46 , C07C323/22 , C07C323/61 , C07C405/00 , C07C405/0033 , C07C45/72 , C07C49/707 , C07C49/753 , C07D233/84 , C07D239/38 , C07D257/04 , C07D263/58 , C07D277/16 , C07D277/74 , C07D303/32 , C07D303/40 , C07D307/38 , C07D307/46 , C07D405/12 , C07D473/38 , C07F7/1856 , C07F7/1864 , C07H13/04 , C07C2101/10 , C07C2101/14
摘要： A 2,3-epoxycyclopentanone represented by the formula (IV): ##STR1## wherein the variables are as defined in the specification, which is used in the preparation of a 2-substituted-2-cyclopentanone compound suitable for use as an anticancer agent and a bone formation accelerator.
摘要翻译：由式（IV）表示的2,3-环氧环戊酮：其中变量如本说明书中所定义，其用于制备适合用作以下物质的2-取代-2-环戊酮化合物抗癌剂和骨形成促进剂。

4. 发明授权

US5338844A 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient 失效
标题翻译： 2-取代-2-环戊烯酮化合物和抗癌剂以及含有活性成分的骨形成促进剂
公开(公告)号：US5338844A
公开(公告)日：1994-08-16
申请号：US104393
申请日：1993-07-16
申请人： Satoshi Sugiura , Toru Minoshima , Atsuo Hazato , Yoshinori Kato
发明人： Satoshi Sugiura , Toru Minoshima , Atsuo Hazato , Yoshinori Kato
IPC分类号： C07C45/72 , C07C49/707 , C07C49/753 , C07C317/24 , C07C317/46 , C07C323/22 , C07C323/61 , C07C405/00 , C07D213/70 , C07D233/84 , C07D239/38 , C07D257/04 , C07D263/58 , C07D277/16 , C07D277/74 , C07D303/40 , C07D307/38 , C07D307/46 , C07D405/12 , C07D473/38 , C07F7/18 , C07H13/04
CPC分类号： C07D213/70 , C07C317/24 , C07C317/46 , C07C323/22 , C07C323/61 , C07C405/0033 , C07C45/72 , C07C49/707 , C07C49/753 , C07D233/84 , C07D239/38 , C07D257/04 , C07D263/58 , C07D277/16 , C07D277/74 , C07D303/40 , C07D307/38 , C07D307/46 , C07D405/12 , C07D473/38 , C07F7/1856 , C07F7/1864 , C07H13/04 , C07C2101/10 , C07C2101/14
摘要： A 2-substituted-2-cyclopentenone compound represented by the following formula (I) and an anticancer agent and a bone formation accelerator comprising the same as an effective active ingredient: ##STR1##
摘要翻译：由下式（I）表示的2-取代-2-环戊烯酮化合物和抗癌剂以及含有作为有效活性成分的骨形成促进剂：（I）

5. 发明授权

US10295638B2 Image processing apparatus, image diagnostic apparatus and image processing method 有权
公开(公告)号：US10295638B2
公开(公告)日：2019-05-21
申请号：US12145089
申请日：2008-06-24
申请人： Satoshi Sugiura
发明人： Satoshi Sugiura
IPC分类号： A61B5/055 , G01R33/563 , G06T17/00 , G01R33/56 , G16H40/63
摘要： An image processing apparatus includes an image data acquisition unit, a development generating unit and a display unit. The image data acquisition unit acquires slice image data with regard to a heart of an object. The development generating unit obtains blood flow perfusion information with regard to a myocardial thickness direction based on the slice image data and generates development data according to a desired development format for displaying the blood flow perfusion information. The display unit displays the development data.

6. 发明授权

US09629569B2 Magnetic resonance imaging apparatus and image generation method for guidance and positioning 有权
公开(公告)号：US09629569B2
公开(公告)日：2017-04-25
申请号：US12425740
申请日：2009-04-17
申请人： Satoshi Sugiura
发明人： Satoshi Sugiura
IPC分类号： A61B5/055 , A61B6/00 , G01R33/56 , G01R33/561 , G01R33/563 , A61B5/00 , G01R33/54
CPC分类号： A61B5/055 , A61B5/0037 , A61B5/7285 , A61B6/488 , A61B6/541 , G01R33/543 , G01R33/5601 , G01R33/5605 , G01R33/5613 , G01R33/5635
摘要： A medical imaging apparatus includes a positioning image acquisition unit which acquires a positioning image concerning a subject, a unit which sets an region of interest in the positioning image in accordance with specification performed by an operator, a monitoring image acquisition unit which repeatedly acquires a monitoring image concerning the subject at predetermined time intervals, and a generation unit which combines an region-of-interest image representing the region of interest with the monitoring image to generate a display image every time the monitoring image is acquired.

7. 发明授权

US09056497B2 Printing control apparatus and printing control method for interruption printing 有权
标题翻译：打印控制装置和中断打印的打印控制方法
公开(公告)号：US09056497B2
公开(公告)日：2015-06-16
申请号：US13052413
申请日：2011-03-21
申请人： Satoshi Sugiura
发明人： Satoshi Sugiura
IPC分类号： B41J29/38 , B41J13/00 , B41J3/60
CPC分类号： B41J13/0045 , B41J3/60 , B41J29/38
摘要： To execute printing on a continuous sheet by using a printing unit, a printing control apparatus includes a reversal unit, an input unit, and a printing control unit. The reversal unit reverses the continuous sheet to execute printing on a second surface of the continuous sheet after executing printing on a first surface of the continuous sheet. The input unit inputs an instruction for executing an interruption print job while executing printing by the printing unit. If instruction for executing the interruption print job is input while the printing of a two-sided print job on the continuous sheet has been currently executed, the printing control unit suspends the two-sided print job, causes the printing unit to execute the interruption print job, and resumes processing of the two-sided print job on the continuous sheet that has been held by the reversal unit after the interruption print job is completed.
摘要翻译：为了通过使用打印单元在连续片上执行打印，打印控制装置包括反转单元，输入单元和打印控制单元。反转单元在连续片材的第一表面上执行印刷之后，反转连续片材以在连续片材的第二表面上执行印刷。输入单元在执行打印单元的打印时输入用于执行中断打印作业的指令。当打印连续纸张上的双面打印作业当前被执行时，如果输入执行中断打印作业的指令，则打印控制单元挂起双面打印作业，使打印单元执行中断打印作业，并且在中断打印作业完成之后恢复在由反转单元保持的连续纸张上的双面打印作业的处理。

8. 发明授权

US08710838B2 Magnetic resonance imaging apparatus 有权
标题翻译：磁共振成像装置
公开(公告)号：US08710838B2
公开(公告)日：2014-04-29
申请号：US12971517
申请日：2010-12-17
申请人： Mitsue Miyazaki , Satoshi Sugiura
发明人： Mitsue Miyazaki , Satoshi Sugiura
IPC分类号： G01V3/00
CPC分类号： G01R33/5635 , G01R33/482 , G01R33/56316
摘要： A magnetic resonance imaging apparatus includes the data gathering unit gathers magnetic resonance data in a non-contrast manner by applying a first readout gradient pulse having a zero-order moment of 0 and second readout gradient pulse having a zero-order moment of 0 and a first-order moment of a value different from a value of a first-order moment of the first readout gradient pulse to a region of interest including a fluid in motion, and periodically arranging first magnetic resonance data readout with the first readout gradient pulse and second magnetic resonance data read out with the second readout gradient pulse in at least one of a phase encoding direction and a slice encoding direction in a k-space to generate k-space data and reconstructs the k-space data to generate an image in which a fluid image and static part image surrounding the fluid are spatially separated from each other.
摘要翻译：磁共振成像装置包括数据采集单元，通过应用具有零阶矩为0的第一读出梯度脉冲和零阶矩为0的第二读出梯度脉冲以及非零对数方式来收集磁共振数据一阶矩，其值与第一读出梯度脉冲的一阶矩的值不同于包括运动中的流体的感兴趣区域，并且周期性地布置具有第一读出梯度脉冲和第二读出梯度脉冲的第一磁共振数据读出在k空间中的相位编码方向和切片编码方向中的至少一个中用第二读出梯度脉冲读出磁共振数据，以产生k空间数据，并且重建k空间数据以产生其中流体图像和围绕流体的静态部分图像在空间上彼此分离。

9. 发明授权

US08515526B2 Magnetic resonance imaging apparatus and magnetic resonance imaging method 有权
标题翻译：磁共振成像装置和磁共振成像方法
公开(公告)号：US08515526B2
公开(公告)日：2013-08-20
申请号：US12694610
申请日：2010-01-27
申请人： Mitsue Miyazaki , Satoshi Sugiura
发明人： Mitsue Miyazaki , Satoshi Sugiura
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , G01R33/5602 , G01R33/5614 , G01R33/56333 , G01R33/5635 , G01R33/56366
摘要： A magnetic resonance imaging apparatus includes a first blood flow image acquisition unit and a second blood flow image acquisition unit. The first blood flow image acquisition unit acquires a first blood flow image of a breast of an object without contrast medium. The second blood flow image acquisition unit acquires a second blood flow image without contrast medium with applying a spin labeling pulse by which a region to be tagged is set based on the first blood flow image as a reference image so as to distinguish blood flowing into a desired region.
摘要翻译：磁共振成像装置包括第一血流图像获取单元和第二血流图像获取单元。第一血流图像获取单元获取没有造影剂的物体的乳房的第一血流图像。第二血流图像获取单元获取没有造影剂的第二血流图像，其中应用基于第一血流图像作为参考图像设置要标记的区域的自旋标记脉冲，以便区分流入所需区域。

10. 发明申请

US20120041299A1 MR IMAGING PROVIDING TISSUE/BLOOD CONTRAST IMAGE 有权
标题翻译：成像提供组织/血液对比图像
公开(公告)号：US20120041299A1
公开(公告)日：2012-02-16
申请号：US13283948
申请日：2011-10-28
申请人： YOSHIMORI KASSAI , Mitsue Miyazaki , Satoshi Sugiura
发明人： YOSHIMORI KASSAI , Mitsue Miyazaki , Satoshi Sugiura
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/0456 , A61B5/7207 , A61B5/7257 , A61B5/7285 , G01R33/4828 , G01R33/5605 , G01R33/5607 , G01R33/5615 , G01R33/5617 , G01R33/5635 , G01R33/5673
摘要： A magnetic resonance imaging (MRI) system obtains an MR image of an object. The system detects an ECG signal and performs a pulse sequence of RF gradient magnetic fields toward the object. Imaging defined by the pulse sequence is longer in temporal length than one heartbeat. The system further acquires an MR signal from the object in response to performance of the pulse sequence and produces the MR image based on the acquired MR signal. Also possible are: a plurality of divided MT pulses instead of the conventional single MT pulse, an SE-system pulse sequence having a shorter echo train spacing, and the generation of sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold.
摘要翻译：磁共振成像（MRI）系统获得物体的MR图像。该系统检测ECG信号，并向对象执行RF梯度磁场的脉冲序列。由脉冲序列定义的成像在时间长度上比一个心跳长。系统还响应于脉冲序列的性能从对象获取MR信号，并且基于所获取的MR信号产生MR图像。还可能的是：多个划分的MT脉冲而不是传统的单个MT脉冲，具有较短回波列间隔的SE系统脉冲序列，以及通过应用结合在成像脉冲序列中的梯度脉冲来产生声音，以便自动地指示患者进行间歇性呼吸。

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