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1. 发明申请

US20050002946A1 Vaccines and agents for inducing immunity in fish against rickettsial diseases, and associated preventative therapy 审中-公开
标题翻译：用于诱导鱼类抗立克次体疾病免疫的疫苗和药剂，以及相关的预防性治疗
公开(公告)号：US20050002946A1
公开(公告)日：2005-01-06
申请号：US10782234
申请日：2004-02-18
申请人： Michael Kuzyk , Jan Burian , William Kay , Julian Thornton
发明人： Michael Kuzyk , Jan Burian , William Kay , Julian Thornton
IPC分类号： A61K39/00 , C07K14/29 , A61K39/38 , A61K39/02
CPC分类号： C07K14/29 , A61K39/00 , A61K2039/53 , C07K2319/00 , Y02A50/403
摘要： The use of the 17 kDa outer surface lipoprotein (OspA) of Piscirickettsia salmonis, or its homologues, as the basis of, or part thereof, a recombinant vaccine for salmonid rickettsial septicaemia and other rickettsial diseases is disclosed. Surface antigens of the bacterial pathogen P. salmonis are characterized and an immunoreactive antigen, namely the 17 kDa outer surface lipoprotein OspA of P. salmonis, as well as the nucleic acid segment that encodes the OspA immunoreactive antigen, is identified and characterized. Diagnostic techniques including the use of hybridization probes and primers as well as the production of specific antigens and antibodies that may be used in immunization techniques for inducing immunity against P. salmonis and other rickettsial diseases are disclosed, as are the development of recombinant vaccines for SRS and other rickettsial diseases based on the 17 kDa lipoprotein OspA. Augmentation of protective immunity by the inclusion of promiscuous T lymphocyte epitopes (TCE's) in fusion protein constructs in salmonids and to the use of bacterial protein inclusion bodies as a source of the protective immunogen is also disclosed.
摘要翻译：公开了使用沙门氏菌属的17kDa外表面脂蛋白（OspA）或其同系物作为鲑鱼样立克次体败血症和其他立克次体疾病的基础或其一部分的重组疫苗。表征细菌病原体沙门氏菌的表面抗原，并鉴定和表征免疫反应性抗原，即沙门氏菌的17kDa外表面脂蛋白OspA以及编码OspA免疫反应性抗原的核酸片段。公开了包括使用杂交探针和引物的诊断技术以及可用于诱导针对鲑鱼和其他立克次体疾病的免疫的免疫技术中的特异性抗原和抗体的产生，以及用于SRS的重组疫苗的开发和基于17kDa脂蛋白OspA的其他立克次体疾病。还公开了通过在混合型T淋巴细胞表位（TCE）中包含鲑鱼中的融合蛋白构建体和使用细菌蛋白包涵体作为保护性免疫原来源来增强保护性免疫。

2. 外观设计

USD989566S1 Rectangular cake cover 有权
公开(公告)号：USD989566S1
公开(公告)日：2023-06-20
申请号：US29780059
申请日：2021-04-22
申请人： William Kay
设计人： William Kay
摘要： FIG. 1 is a perspective view of a rectangular cake cover, showing my new design;
FIG. 2 is a front elevational view of the rectangular cake cover thereof;
FIG. 3 is a rear elevational view of the rectangular cake cover thereof;
FIG. 4 is a left side elevational view of the rectangular cake cover thereof;
FIG. 5 is a right side elevational view of the rectangular cake cover thereof;
FIG. 6 is a top plan view of the rectangular cake cover thereof; and,
FIG. 7 is a bottom plan view of the rectangular cake cover thereof.
The broken lines in the drawings illustrate environmental subject matter and form no part of the claimed design.

3. 外观设计

USD937042S1 Cake slice cover 有权
公开(公告)号：USD937042S1
公开(公告)日：2021-11-30
申请号：US29745376
申请日：2020-08-05
申请人： William Kay
设计人： William Kay

4. 发明授权

US12059086B2 Cake shield 有权
公开(公告)号：US12059086B2
公开(公告)日：2024-08-13
申请号：US16990652
申请日：2020-08-11
申请人： William Kay
发明人： William Kay
IPC分类号： A47G19/26
CPC分类号： A47G19/26
摘要： A cake shield with a top cover and side wall dimensioned to enclose a cake to prevent contamination during celebration is disclosed. Recesses in the top cover may include a recessed track dimensioned to hold multiple candles, a deeper cylindrical or conical recess, or a recess dimensioned for a candle with a rectangular footprint. Use of transparent material allows the cake to be viewed under the shield. The cake shield may comprise a base wall that supports the side wall of the top cover, and two or more pieces may interlock to form the base wall. A kit may also include a base plate for supporting both the cake and the side wall, as well as decorations for the top cover that may include candles and other materials.

5. 发明申请

US20210369024A1 CAKE SHIELD 有权
公开(公告)号：US20210369024A1
公开(公告)日：2021-12-02
申请号：US16990652
申请日：2020-08-11
申请人： William Kay
发明人： William Kay
IPC分类号： A47G19/26
摘要： A cake shield with a top cover and side wall dimensioned to enclose a cake to prevent contamination during celebration is disclosed. Recesses in the top cover may include a recessed track dimensioned to hold multiple candles, a deeper cylindrical or conical recess, or a recess dimensioned for a candle with a rectangular footprint. Use of transparent material allows the cake to be viewed under the shield. The cake shield may comprise a base wall that supports the side wall of the top cover, and two or more pieces may interlock to form the base wall. A kit may also include a base plate for supporting both the cake and the side wall, as well as decorations for the top cover that may include candles and other materials.

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