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1. 发明申请

US20070008289A1 Computer Keyboard 失效
标题翻译：电脑键盘
公开(公告)号：US20070008289A1
公开(公告)日：2007-01-11
申请号：US11382703
申请日：2006-05-10
申请人： Michael Franks , Daniel O'Neil , David Lane
发明人： Michael Franks , Daniel O'Neil , David Lane
IPC分类号： G09G5/00
CPC分类号： G06F3/0231 , G06F3/0219
摘要： A keyboard has a middle region that has upward longitudinal slopes rising to upper planes on both sides of the middle region. An alphanumeric section disposed in the keyboard housing generally in the middle region. The keyboard includes a first wing section and the second wing section in which each can be disposed at height of the keyboard housing at the upper plane. In one aspect, the alphanumeric section may be disposed below the height of the first and second wing section, and the alphanumeric section is laterally disposed between the first medial section and the second media section.
摘要翻译：键盘具有中间区域，该中间区域具有上升到中间区域两侧的上平面的纵向斜面。位于键盘外壳中的大致在中间区域的字母数字部分。键盘包括第一翼部分和第二翼部分，其中每个翼部分可以在键盘壳体的高度处设置在上平面处。在一个方面，字母数字部分可以设置在第一和第二翼部分的高度的下方，并且字母数字部分横向设置在第一中间部分和第二媒体部分之间。

2. 发明申请

US20060088160A1 Method and apparatus for generating and printing a security stamp with custom logo on an electrophotographic printer 审中-公开
标题翻译：用于在电子照相打印机上产生和打印带有自定义徽标的安全印章的方法和装置
公开(公告)号：US20060088160A1
公开(公告)日：2006-04-27
申请号：US10976293
申请日：2004-10-27
申请人： Rickey Brown , Kevin Eby , Cuong Hoang , David Lane , Richard Russell
发明人： Rickey Brown , Kevin Eby , Cuong Hoang , David Lane , Richard Russell
IPC分类号： G09C3/08
CPC分类号： H04N1/32144 , H04N1/32203 , H04N2201/3201 , H04N2201/3271
摘要： An improved electrophotographic printer is provided for generating a security stamp in firmware, and printing that security stamp to create documents that have a visible and tactile logo that is automatically printed on each page of a print job. The firmware will automatically create the proper bitmap of the security logo for a page's print resolution and bit depth. Using a color laser printer, the security stamp can be printed using all of the process colors, such as CMYK, which would be rendered and printed at 400% toner coverage. This gives the security stamp a very dark visible appearance and a thick tactile texture. The security stamp can include an area for printing a serial number of the printer, and for printing a time and date stamp.
摘要翻译：提供了一种改进的电子照相打印机，用于在固件中生成安全印章，并打印该安全印章以创建具有自动打印在打印作业的每一页上的可见和触觉标志的文档。固件将自动为页面的打印分辨率和位深度创建安全徽标的正确位图。使用彩色激光打印机，可以使用所有处理颜色打印安全印章，如CMYK，将以400％的墨粉覆盖率进行渲染和打印。这给安全印章一个非常暗的可见外观和厚厚的触觉纹理。安全印章可以包括用于打印打印机的序列号的区域，以及打印时间和日期戳。

3. 发明申请

US20140045262A1 CONSTRUCTS AND METHOD FOR REGULATING GENE EXPRESSION OR FOR DETECTING AND CONTROLLING A DNA LOCUS IN EUKARYOTES 有权
标题翻译：用于调节基因表达或用于检测和控制DNA位置的构建体和方法
公开(公告)号：US20140045262A1
公开(公告)日：2014-02-13
申请号：US14006743
申请日：2012-03-23
申请人： Kerstin Bystricky , Franck Gallardo , David Lane , Nelly Dubarry
发明人： Kerstin Bystricky , Franck Gallardo , David Lane , Nelly Dubarry
IPC分类号： C12N15/85 , C12N15/81
CPC分类号： C12N15/85 , C07K14/21 , C07K2319/80 , C12N15/81 , C12N15/8212 , C12N15/8216
摘要： The present invention concerns constructs based on sequences derived from the partitioning system of plasmid and chromosomal DNA of bacteria, such as eukaryotic expression vectors, fusion proteins and polynucleotides encoding the same and also eukaryotic cells transformed with or expressing such constructs. The present invention also concerns the use thereof in the regulation of gene expression and/or in the detection and control of the dynamics, localization or metabolism of genomic DNA loci of interest in eukaryotic cells.
摘要翻译：本发明涉及基于衍生自细菌的分化系统和染色体DNA的序列的构建体，例如真核表达载体，融合蛋白和编码它们的多核苷酸以及用这些构建体转化或表达的真核细胞。本发明还涉及其在调节基因表达和/或在真核细胞中检测和控制感兴趣的基因组DNA位点的动力学，定位或代谢的用途。

4. 发明申请

US20070070425A1 Object-based sharpening for an image forming device 审中-公开
标题翻译：用于图像形成装置的基于对象的锐化
公开(公告)号：US20070070425A1
公开(公告)日：2007-03-29
申请号：US11239277
申请日：2005-09-29
申请人： David Lane
发明人： David Lane
IPC分类号： H04N1/405
CPC分类号： H04N1/405 , G06K15/02
摘要： A method and apparatus for sharpening objects formed by an image forming unit. Page objects in print requests may be identified as being one of several different types. Boundaries of the page objects may be eroded according to the type of the page objects, thus defining an eroded boundary. Rectangular objects may be identified by height and width, the boundary eroded by reducing the height and/or width. Character objects may be identified and eroded by performing an AND operation between the original character and a shifted character. Irregular objects may be identified from one or more edge lists and boundaries may be eroded by increasing or decreasing the edge list values. Different halftone screen frequencies may be applied when rendering areas divided by the eroded boundaries. The edges of the objects may be rendered using a higher screen frequency.
摘要翻译：一种用于磨削由图像形成单元形成的物体的方法和装置。打印请求中的页面对象可以被识别为几种不同类型之一。页面对象的边界可能会根据页面对象的类型进行侵蚀，从而定义了一个侵蚀的边界。矩形物体可以通过高度和宽度来识别，边界通过降低高度和/或宽度而被侵蚀。字符对象可以通过执行原始字符和移位字符之间的“与”运算来识别和侵蚀。可以从一个或多个边缘列表识别不规则对象，并且可以通过增加或减少边缘列表值来侵蚀边界。当渲染区域被侵蚀的边界划分时，可以应用不同的半色调屏幕频率。可以使用更高的屏幕频率渲染对象的边缘。

5. 发明申请

US20060291946A1 Ergonomic apparatus for keyboard 审中-公开
标题翻译：符合人体工学的键盘设备
公开(公告)号：US20060291946A1
公开(公告)日：2006-12-28
申请号：US11165715
申请日：2005-06-24
申请人： Daniel Odell , David Lane
发明人： Daniel Odell , David Lane
IPC分类号： G06F3/023
CPC分类号： G06F3/0208
摘要： A plurality of embodiments of ergonomic apparatus for keyboards are provided for interfacing with a user's arms, wrists, hands and fingers in a more natural way, i.e., in ways that are optimally suited to human typing. The ergonomic apparatus for a keyboard includes structures that reduce extension of human hands while typing on the keyboard. An attachable frame component may be provided which, when attached to a keyboard near its front (the front being closest to the user), the frame component elevates the front of the keyboard thereby achieving a reverse slope of an upper surface of the keyboard.
摘要翻译：提供了用于键盘的人体工程学设备的多个实施例，用于以更自然的方式即以最适合于人类打字的方式与用户的手臂，手腕，手和手指进行接口。用于键盘的符合人体工程学的设备包括在键盘上打字时减少人手伸展的结构。可以提供一种可附接的框架部件，当其靠近其前部（前部最靠近使用者）附近的键盘时，框架部件升高键盘的前部，从而实现键盘的上表面的相反斜率。

6. 发明申请

US20050137137A1 Inhibitors of the Interaction between p53 and MDM2 审中-公开
标题翻译： p53和MDM2之间相互作用的抑制剂
公开(公告)号：US20050137137A1
公开(公告)日：2005-06-23
申请号：US10927262
申请日：2004-08-25
申请人： David Lane , Volker Bottger , Angelika Bottger , Steven Picksley , Heinz-Kurt Hochkeppel , Carlos Garcia-Echeverria , Patrick Chene , Pascal Furet
发明人： David Lane , Volker Bottger , Angelika Bottger , Steven Picksley , Heinz-Kurt Hochkeppel , Carlos Garcia-Echeverria , Patrick Chene , Pascal Furet
IPC分类号： G01N33/53 , A61K38/00 , A61K45/00 , A61P35/00 , C07K7/04 , C07K7/06 , C07K7/08 , C07K14/82 , C12N15/09 , C12Q1/68 , A61K38/08
CPC分类号： C07K7/04 , A61K38/00 , C07K2319/00
摘要： The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounds, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild type p53 suppressor by interfering with the interaction between human p53 and human MDM2.
摘要翻译：本发明涉及能够结合致癌基因蛋白MDM2的化合物，制备这些化合物的方法，包含这些化合物的药物制剂，以及所述化合物的用途，例如，在动物或特别是人体的治疗（包括预防性）治疗中。本发明还涉及通过干扰人p53与人MDM2之间的相互作用来抑制包含野生型p53抑制因子的肿瘤细胞生长的方法和化合物。

7. 发明授权

US4946406A Electrical connector which requires no application tool 失效
标题翻译：不需要应用工具的电气连接器
公开(公告)号：US4946406A
公开(公告)日：1990-08-07
申请号：US354177
申请日：1989-05-19
申请人： David Lane , Richard A. Nelson
发明人： David Lane , Richard A. Nelson
IPC分类号： H01R4/24 , H01R4/48
CPC分类号： H01R4/2433
摘要： Preloaded electrical connector comprises a housing having a terminal therein which is partially inserted into a terminal-receiving cavity. The terminal has a wire contacting lancet thereon and the housing cavity has camming wall portions which are effective, during movement of the terminal to its fully inserted position, to move the contacting lancet into engagement with a wire. Installation is carried out by inserting a wire into the partially inserted terminal and then moving the terminal from its partially inserted position to its fully inserted position. No specialized tooling is required for the installation process.

8. 发明授权

US4883433A Electrical connector for data distribution panel 失效
标题翻译：数据配电面板电气连接器
公开(公告)号：US4883433A
公开(公告)日：1989-11-28
申请号：US136090
申请日：1987-12-21
申请人： David Lane
发明人： David Lane
IPC分类号： H01R13/518 , H01R13/639
CPC分类号： H01R13/518 , H01R13/639 , H01R2201/04 , Y10S439/939
摘要： An electrical connector is disclosed which is for use with a patch cable on a data distribution panel. Connectors are placed at each end of the cable and can be latchably interconnected to the panel to interconnect shielded subassemblies together. A data distribution panel includes a conductive panel having openings for the receipt of shielded electrical data connectors from the rear thereof and are electrically commoned to the panel. The electrical connectors are in the form of shielded subassemblies which, when interconnected to the panel, are commoned by a finger which extends from the panel thereby contacting the subassemblies.
摘要翻译：公开了一种电连接器，其用于数据配线面板上的贴片电缆。连接器放置在电缆的每个端部，并且可以可闩锁地连接到面板以将屏蔽的子组件互连在一起。数据分配面板包括具有用于从其后部接收屏蔽电气数据连接器的开口的导电板，并且与面板电气共用。电连接器是屏蔽子组件的形式，当与面板相互连接时，其通过从面板延伸的手指通常接触，从而接触子组件。

9. 发明授权

US4372637A Bond shield terminal 失效
标题翻译：债券盾牌终端
公开(公告)号：US4372637A
公开(公告)日：1983-02-08
申请号：US252769
申请日：1981-04-10
申请人： David Lane , Mervin Woodward , Jerry B. Kilpatrick
发明人： David Lane , Mervin Woodward , Jerry B. Kilpatrick
IPC分类号： H01R4/48 , H01R4/64
CPC分类号： H01R4/48 , H01R4/64 , Y10T24/44034
摘要： A bond shield terminal formed of two hermaphroditic elements of substantially identical shape, each element being lockable in the other and providing a force on a shield of a pair of wires positioned therebetween. Each of the hermaphroditic elements includes a base and a pair of latching arms depending from one adjacent pair of corners of the base, each of the latching arms having a pair of spaced apertures therein and a pair of legs depending from the other two corners of the base, each of the legs having a latching finger formed therein for locking into the apertures of the mating element. A pair of spring arms is formed in the base and depends therefrom in the same direction as the arms and legs, each of the spring arms having extensions for applying a force to wires between a pair of elements to provide a compressive force against the wires and maintain the metal shields thereof in compression against each other to provide good electrical contact.
摘要翻译：由两个基本相同形状的同构元件形成的键合屏蔽端子，每个元件可锁定在另一个中并且在位于它们之间的一对电线的屏蔽上提供力。每个雌雄同体元件包括基部和一对闩锁臂，其从基部的相邻的一对拐角悬垂，每个锁定臂在其中具有一对间隔开的孔，并且一对支腿从其中的另一个两个角落下每个腿具有形成在其中的锁定指状件，用于锁定到配合元件的孔中。一对弹簧臂形成在基座中并且与臂和腿沿着相同的方向从其中延伸，每个弹簧臂具有用于对一对元件之间的线施加力的延伸部，以提供抵抗电线的压缩力，保持其金属屏蔽彼此压缩以提供良好的电接触。

10. 发明授权

US09611486B2 Constructs and method for regulating gene expression or for detecting and controlling a DNA locus in eukaryotes 有权
公开(公告)号：US09611486B2
公开(公告)日：2017-04-04
申请号：US14006743
申请日：2012-03-23
申请人： Kerstin Bystricky , Franck Gallardo , David Lane , Nelly Dubarry
发明人： Kerstin Bystricky , Franck Gallardo , David Lane , Nelly Dubarry
IPC分类号： C12N15/63 , C12N15/82 , C12N15/85 , C07K14/21 , C12N15/81 , C12N5/07 , C12N5/071 , C12N5/10
CPC分类号： C12N15/85 , C07K14/21 , C07K2319/80 , C12N15/81 , C12N15/8212 , C12N15/8216
摘要： The present invention concerns constructs based on sequences derived from the partitioning system of plasmid and chromosomal DNA of bacteria, such as eukaryotic expression vectors, fusion proteins and polynucleotides encoding the same and also eukaryotic cells transformed with or expressing such constructs. The present invention also concerns the use thereof in the regulation of gene expression and/or in the detection and control of the dynamics, localization or metabolism of genomic DNA loci of interest in eukaryotic cells.

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