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1. 发明授权

US08039262B2 Method for controlling a tissue processor and tissue processor 有权
标题翻译：用于控制组织处理器和组织处理器的方法
公开(公告)号：US08039262B2
公开(公告)日：2011-10-18
申请号：US12545586
申请日：2009-08-21
申请人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
发明人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
IPC分类号： C12Q3/00 , C12M1/36 , C12M3/00 , G01N33/48
CPC分类号： G01N35/00623 , Y10T436/11 , Y10T436/115831 , Y10T436/12
摘要： A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided including a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented.
摘要翻译：描述了一种用于控制组织处理器和用于处理组织样本的组织处理器的方法。提供了一种蒸煮器，其包括可由操作者打开和关闭的盖子。在组织处理之前关闭蒸煮盖。可以确定第一和第二操作元件的致动状态。提示操作者通过致动第二操作元件来确认关闭的蒸煮盖的解锁。当确定第二操作元件的致动并且关闭的蒸煮盖被解锁并在蒸煮盖再次被锁定之后继续时，纸巾处理被中断。在完成纸巾处理后，解冻盖子。通过所描述的方法和组织处理器，防止在持续的组织处理期间不适当的干预。

2. 发明申请

US20100055663A1 METHOD FOR CONTROLLING A TISSUE PROCESSOR AND TISSUE PROCESSOR 有权
标题翻译：用于控制组织处理器和组织处理器的方法
公开(公告)号：US20100055663A1
公开(公告)日：2010-03-04
申请号：US12545586
申请日：2009-08-21
申请人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
发明人： Marc Konrad , Holger Metzner , Udo Hermann , Frank Meder , Hermann Ulbrich , Markus Dobusch , Stefan Künkel
IPC分类号： C12M1/00 , C12Q3/00
CPC分类号： G01N35/00623 , Y10T436/11 , Y10T436/115831 , Y10T436/12
摘要： A method for controlling a tissue processor and a tissue processor for processing tissue samples is described. A retort is provided comprising a cover that can be opened and closed by an operator. The retort cover is closed prior to tissue processing. The actuation state of a first and a second operating element can be determined. An operator is prompted to confirm unlocking of the closed retort cover by actuating a second operating element. The tissue processing is interrupted when an actuation of the second operating element is determined and the closed retort cover is unlocked and is continued after the retort cover is once again locked. After having completed tissue processing the retort cover is unlocked. By means of the described method and tissue processor improper intervention during ongoing tissue processing is prevented.
摘要翻译：描述了一种用于控制组织处理器和用于处理组织样本的组织处理器的方法。提供了一种蒸煮器，其包括可由操作者打开和关闭的盖子。在组织处理之前关闭蒸煮盖。可以确定第一和第二操作元件的致动状态。提示操作者通过致动第二操作元件来确认关闭的蒸煮盖的解锁。当确定第二操作元件的致动并且关闭的蒸煮盖被解锁并在蒸煮盖再次被锁定之后继续时，纸巾处理被中断。在完成纸巾处理后，解冻盖子。通过所描述的方法和组织处理器，防止在持续的组织处理期间不适当的干预。

3. 发明授权

US07722811B2 Tissue processor 有权
标题翻译：组织处理器
公开(公告)号：US07722811B2
公开(公告)日：2010-05-25
申请号：US11562710
申请日：2006-11-22
申请人： Marc Konrad , Stefan Künkel , Holger Metzner , Eberhard Sendobry , Markus Dobusch
发明人： Marc Konrad , Stefan Künkel , Holger Metzner , Eberhard Sendobry , Markus Dobusch
IPC分类号： G01N21/00
CPC分类号： G01N1/31 , B01L3/16 , G01N35/1067 , G01N35/1072 , Y10T436/113332
摘要： A tissue processor (1) is described, having a retort (2) for processing histological samples with different reagents, having multiple reagent reservoir vessels (3), and having a conduit system and a control device (5) for delivering reagents out of the reagent reservoir vessels (3) into the retort (2). A suction conduit (11) projects into each reagent reservoir vessel (3) through the vessel opening (7) for reagent withdrawal. A closure system (12) having an externally tapered and internally hollow closure plug (13) is provided for closing off the vessel opening (7). The suction conduit (11) is guided through a cavity (14) of the closure plug (13) for reagent withdrawal.
摘要翻译：描述了一种组织处理器（1），其具有用于用不同试剂处理组织学样品的蒸馏器（2），具有多个试剂储存容器（3），并具有导管系统和控制装置（5），用于将试剂输出试剂库容器（3）进入蒸馏器（2）。抽吸管道（11）通过容器开口（7）突出到每个试剂储存容器（3）中以用于试剂取出。提供具有外锥形和内部中空的封闭塞（13）的封闭系统（12），用于封闭容器开口（7）。吸入管道（11）被引导通过封闭塞（13）的空腔（14）以用于试剂取出。

4. 发明申请

US20130141246A1 Display Of A System State Of A Treatment Device For Microscopic Samples 有权
标题翻译：显微镜样品处理装置的系统状态
公开(公告)号：US20130141246A1
公开(公告)日：2013-06-06
申请号：US13509421
申请日：2010-11-15
申请人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
发明人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
IPC分类号： G08B5/36
CPC分类号： G08B5/36 , G01N1/36 , G01N2035/00891
摘要： The invention relates to a method of displaying a system state of an automatic treatment device, a corresponding display system which is configured for carrying out the method, and a treatment device equipped with the display system. At least one system parameter (121, 122, 123) is determined, the at least one determined (120) system parameter (121, 122, 123) is evaluated on the basis of evaluation criteria, the system state is evaluated on the basis of the at least one evaluated (130) system parameter (121, 122, 123), and the evaluated (140) system state is displayed by a traffic light function (175).
摘要翻译：本发明涉及一种显示自动处理装置的系统状态的方法，配置为执行该方法的相应显示系统以及配备有显示系统的处理装置。确定至少一个系统参数（121,122,123），基于评估标准来评估至少一个确定的（120）系统参数（121,122,123），系统状态基于通过交通灯功能（175）显示所述至少一个评估系统参数（121,122,123）和所述评估（140）系统状态。

5. 发明申请

US20120052526A1 Tissue Infiltration Method 有权
标题翻译：组织浸润法
公开(公告)号：US20120052526A1
公开(公告)日：2012-03-01
申请号：US13271953
申请日：2011-10-12
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet I. Minshew
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet I. Minshew
IPC分类号： C12Q1/02
CPC分类号： G01N1/31 , Y10T436/2575
摘要： A tissue infiltration apparatus (1) for specimens present in cassettes (5) comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to, and/or movable away from, a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) is definable. To enable accelerated or preferred processing of a transport basket (4) with the tissue infiltration apparatus (1), at least one means (8) is provided with which the order of two transport baskets (4) is definably modifiable.
摘要翻译：用于盒（5）中的样本的组织浸渗装置（1）包括至少两个液体容器（7,11,13,15）和输送装置（6）。多个盒（5）可接收在运输篮（4）中。输送装置（6）构造成使得至少两个输送筐（4）能够在组织浸渗装置（1）中运输。运输篮（4）可与运输设备（6）一起运送到和/或移动离开液体容器（7,11,13,15）。运输篮（4）通过液体容器（7,11,13,15）的执行顺序（21）是可定义的。为了能够利用组织渗透装置（1）加速或优选地加工运输篮（4），提供至少一个装置（8），两个运输篮（4）的顺序是可定义地可修改的。

6. 发明授权

US08431091B2 Tissue embedding apparatus, and method for operating a tissue embedding apparatus 有权
标题翻译：组织嵌入装置和组织嵌入装置的操作方法
公开(公告)号：US08431091B2
公开(公告)日：2013-04-30
申请号：US12599050
申请日：2008-04-23
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel
IPC分类号： A61B10/00
CPC分类号： G01N1/31 , G01N1/36
摘要： The invention relates to a tissue embedding apparatus (1) for automatic embedding at least one tissue sample (8). Said tissue embedding device (1) comprises an input unit (2), an image recording unit (3), an embedding unit (4), at least one output unit (5, 6), and a control unit (7). A cassette (9) containing at least one tissue sample (8) can be transferred to the input unit (2) of the tissue embedding device (1). The embedding unit (4) allows the tissue sample (8) to be embedded in an embedding medium, while the at least one output unit (5) allows the embedded tissue sample to be output. The image recording unit (3) makes it possible to record at least one image of the tissue sample (8). In order to be able to embed tissue in an automated manner also when different cassettes are used, a tissue embedding device (1) according to the invention is characterized in that the recorded image of the tissue sample (8) can be evaluated while further processing of the tissue sample (8) in the tissue embedding device (1) can be predefined in accordance with the evaluation of the image.
摘要翻译：本发明涉及一种用于自动包埋至少一个组织样品（8）的组织包埋装置（1）。所述组织嵌入装置（1）包括输入单元（2），图像记录单元（3），嵌入单元（4），至少一个输出单元（5,6）和控制单元（7）。包含至少一个组织样本（8）的盒（9）可以被传送到组织嵌入装置（1）的输入单元（2）。嵌入单元（4）允许组织样本（8）嵌入到嵌入介质中，而至少一个输出单元（5）允许输出嵌入的组织样本。图像记录单元（3）使得可以记录组织样本（8）的至少一个图像。为了能够在使用不同的盒子时能够以自动方式嵌入组织，根据本发明的组织包埋装置（1）的特征在于可以进一步处理组织样本（8）的记录图像，可以根据图像的评估来预先确定组织包埋装置（1）中的组织样本（8）。

7. 发明授权

US08890709B2 Display of a system state of a treatment device for microscopic samples 有权
标题翻译：显示微观样品处理装置的系统状态
公开(公告)号：US08890709B2
公开(公告)日：2014-11-18
申请号：US13509421
申请日：2010-11-15
申请人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
发明人： Michael Thiel , Hermann Ulbrich , Martin Zwicklowsky , Michael Erben , Michael Rapp , Stefan Künkel , Udo Herrmann
IPC分类号： G08B5/36 , G01N1/36 , G01N35/00
CPC分类号： G08B5/36 , G01N1/36 , G01N2035/00891
摘要： The invention relates to a method of displaying a system state of an automatic treatment device, a corresponding display system which is configured for carrying out the method, and a treatment device equipped with the display system. At least one system parameter (121, 122, 123) is determined, the at least one determined (120) system parameter (121, 122, 123) is evaluated on the basis of evaluation criteria, the system state is evaluated on the basis of the at least one evaluated (130) system parameter (121, 122, 123), and the evaluated (140) system state is displayed by a traffic light function (175).
摘要翻译：本发明涉及一种显示自动处理装置的系统状态的方法，配置为执行该方法的相应显示系统以及配备有显示系统的处理装置。确定至少一个系统参数（121,122,123），基于评估标准来评估至少一个确定的（120）系统参数（121,122,123），系统状态基于通过交通灯功能（175）显示所述至少一个评估系统参数（121,122,123）和所述评估（140）系统状态。

8. 发明授权

US08277730B2 Tissue infiltration method 有权
标题翻译：组织浸润法
公开(公告)号：US08277730B2
公开(公告)日：2012-10-02
申请号：US13271953
申请日：2011-10-12
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet Minshew
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet Minshew
IPC分类号： G01N21/00
CPC分类号： G01N1/31 , Y10T436/2575
摘要： A tissue infiltration apparatus (1) for specimens present in cassettes (5) comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to, and/or movable away from, a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) is definable. To enable accelerated or preferred processing of a transport basket (4) with the tissue infiltration apparatus (1), at least one means (8) is provided with which the order of two transport baskets (4) is definably modifiable.
摘要翻译：用于盒（5）中的样本的组织浸渗装置（1）包括至少两个液体容器（7,11,13,15）和输送装置（6）。多个盒（5）可接收在运输篮（4）中。输送装置（6）构造成使得至少两个输送筐（4）能够在组织浸渗装置（1）中运输。运输篮（4）可与运输设备（6）一起运送到和/或移动离开液体容器（7,11,13,15）。运输篮（4）通过液体容器（7,11,13,15）的执行顺序（21）是可定义的。为了能够利用组织渗透装置（1）加速或优选地加工运输篮（4），提供至少一个装置（8），两个运输篮（4）的顺序是可定义地可修改的。

9. 发明授权

US08052928B2 Tissue infiltration apparatus 有权
标题翻译：组织浸润装置
公开(公告)号：US08052928B2
公开(公告)日：2011-11-08
申请号：US12031800
申请日：2008-02-15
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet I. Minshew
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel , Janet I. Minshew
IPC分类号： G01N21/00
CPC分类号： G01N1/31 , Y10T436/2575
摘要： A tissue infiltration apparatus (1) for specimens present in cassettes (5). comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). A liquid having a definable property is introducible into a liquid container (7, 11, 13, 15). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that with it, at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to a liquid container (7, 11, 13, 15) and/or movable away from a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) of the tissue infiltration apparatus (1) is definable. To enable accelerated or preferred processing of a transport basket (4) with the tissue infiltration apparatus (1), but without using an additional liquid container provided only for that purpose, at least one means (8) is provided with which the order of two transport baskets (4) is definably modifiable.
摘要翻译：用于盒（5）中存在的标本的组织浸润装置（1）。包括至少两个液体容器（7,11,13,15）和输送装置（6）。具有可定义特性的液体可引入液体容器（7,11,13,15）。多个盒（5）可接收在运输篮（4）中。输送装置（6）以这样的方式配置：至少两个输送篮（4）可在组织浸渗装置（1）中运输。运输篮（4）可输送到液体容器（7,11,13,15）和/或可与运输设备（6）一起离开液体容器（7,11,13,15）移动。输送筐（4）通过组织浸渗装置（1）的液体容器（7,11,13,15）的执行顺序（21）是可定义的。为了能够利用组织浸渗装置（1）加速或优选地处理运输篮（4），但是不使用仅为此目的提供的另外的液体容器，提供至少一个装置（8），其具有两个运输篮（4）是可定义的。

10. 发明申请

US20100248301A1 Tissue Embedding Apparatus, And Method For Operating A Tissue Embedding Apparatus 有权
标题翻译：组织嵌入装置及操作组织嵌入装置的方法
公开(公告)号：US20100248301A1
公开(公告)日：2010-09-30
申请号：US12599050
申请日：2008-04-23
申请人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel
发明人： Hermann Ulbrich , Karl-Heinz Westerhoff , Stefan Künkel
IPC分类号： G01N1/30 , G01N1/31
CPC分类号： G01N1/31 , G01N1/36
摘要： The present invention relates to a tissue embedding apparatus (1) for automatic embedding of at least one tissue sample (8). The tissue embedding apparatus (1) encompasses an input unit (2), an image acquisition unit (3), an embedding unit (4), at least one output unit (5, 6), and a control unit (7). A cassette (9) containing at least one tissue sample (8) is transferable to the input unit (2) of the tissue embedding apparatus (1). The tissue sample (8) is embeddable in an embedding medium by means of the embedding unit (4). The embedded tissue sample is outputtable with the at least one output unit (5). At least one image of the tissue sample (8) is acquirable with the image acquisition unit (3). In order for automated tissue embedding to be achievable even with the use of different cassettes, a tissue embedding apparatus (1) according to the present invention is characterized in that the image acquired of the tissue sample (8) is evaluatable, and the further processing of the tissue sample (8) in the tissue embedding apparatus (1) is definable as a function of the image evaluation.
摘要翻译：本发明涉及一种用于自动嵌入至少一个组织样品（8）的组织包埋装置（1）。组织嵌入装置（1）包括输入单元（2），图像获取单元（3），嵌入单元（4），至少一个输出单元（5,6）和控制单元（7）。包含至少一个组织样本（8）的盒（9）可转移到组织嵌入装置（1）的输入单元（2）。组织样品（8）可以通过嵌入单元（4）嵌入嵌入介质中。所述嵌入的组织样本可与所述至少一个输出单元（5）一起输出。所述组织样本（8）的至少一个图像可与所述图像获取单元（3）进行获取。为了即使使用不同的盒也能够实现自动组织包埋，根据本发明的组织包埋装置（1）的特征在于，可以评估获取的组织样品（8）的图像，并且进一步处理作为图像评价的函数来定义组织嵌入装置（1）中的组织样本（8）。

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