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1. 发明授权

US08970858B2 Operator guidance system and image forming apparatus incorporating same 有权
标题翻译：操作者引导系统和包含其的图像形成装置
公开(公告)号：US08970858B2
公开(公告)日：2015-03-03
申请号：US13678671
申请日：2012-11-16
申请人： Mami Akiyama , Yasuhiro Sagawa , Masaharu Furuya , Manabu Izumikawa , Mikio Ishibashi , Yoshio Hattori , So Ohta , Ryo Takenaka , Hiroaki Murakami
发明人： Mami Akiyama , Yasuhiro Sagawa , Masaharu Furuya , Manabu Izumikawa , Mikio Ishibashi , Yoshio Hattori , So Ohta , Ryo Takenaka , Hiroaki Murakami
IPC分类号： G06F3/12 , G03G15/00
CPC分类号： G06F3/12 , G03G15/502 , G03G15/70
摘要： An operator guidance system includes a detection unit, a control unit, and an operation indicator. The detection unit is disposed in an image forming apparatus to output a combination of detection signals, and includes one or more media sensors, and one or more opening sensors. The one or more media sensors are disposed along a media conveyance path to output a media detection signal. The one or more opening sensors are disposed adjacent to an openable structure to output an opening detection signal. The control unit is connected to the detection unit to determine guidance to be provided to an operator based on the combination of detection signals, and includes a memory and a controller. The operation indicator is connected to the control unit to indicate the identified operation to the operator.
摘要翻译：操作者引导系统包括检测单元，控制单元和操作指示器。检测单元设置在图像形成装置中以输出检测信号的组合，并且包括一个或多个介质传感器和一个或多个打开传感器。一个或多个介质传感器沿着介质传送路径布置以输出介质检测信号。一个或多个打开传感器被布置成与可打开的结构相邻以输出打开检测信号。控制单元连接到检测单元，以基于检测信号的组合确定要提供给操作者的指导，并且包括存储器和控制器。操作指示器连接到控制单元以向操作者指示所识别的操作。

2. 发明授权

US06638509B1 Toxin conjugates 失效
标题翻译：毒素结合物
公开(公告)号：US06638509B1
公开(公告)日：2003-10-28
申请号：US09500243
申请日：2000-02-08
申请人： Toshiyuki Suzawa , Motoo Yamasaki , Satoru Nagamura , Hiromitsu Saito , So Ohta , Nobuo Hanai
发明人： Toshiyuki Suzawa , Motoo Yamasaki , Satoru Nagamura , Hiromitsu Saito , So Ohta , Nobuo Hanai
IPC分类号： A61K3940
CPC分类号： A61K39/44 , A61K47/6809 , A61K47/6817 , A61K47/6889 , C07K17/06
摘要： The present invention relates to a toxin conjugate in which a residue derived from a compound having an affinity for a target cell is bound to a toxin through a spacer comprising polyalkylene glycol and dipeptide.
摘要翻译：本发明涉及一种毒素结合物，其中衍生自对靶细胞具有亲和力的化合物的残基通过包含聚亚烷基二醇和二肽的间隔物与毒素结合。

3. 发明申请

US20070138416A1 Sheet detector, sheet detector mechanism and image forming apparatus 失效
标题翻译：片材检测器，片材检测器机构和成像设备
公开(公告)号：US20070138416A1
公开(公告)日：2007-06-21
申请号：US11642709
申请日：2006-12-21
申请人： So Ohta , Masataka Shimoohsako , Noriaki Fukube , Tetsuya Ohfuchi
发明人： So Ohta , Masataka Shimoohsako , Noriaki Fukube , Tetsuya Ohfuchi
IPC分类号： G01N21/86
CPC分类号： B65H7/14 , B65H2511/416 , B65H2511/51 , B65H2515/60 , B65H2515/702 , B65H2553/412 , B65H2553/416 , B65H2557/64 , B65H2220/02 , B65H2220/04 , B65H2220/03 , B65H2220/01
摘要： A sheet detector, a sheet detector mechanism and an image forming apparatus. An image forming apparatus may include an image forming mechanism, a sheet conveyance mechanism, and a sheet detector. The image forming mechanism may form an image and transfer the image onto the sheet conveyed by the sheet conveyance mechanism. The sheet detector may be arranged upstream from an image transfer region and configured to detect the sheet. The sheet detector may include a light source emitting light, a plurality of photoreceptors, and a controller. The plurality of photoreceptors may be arranged in a line in a main-scanning direction and may include a first photoreceptor group and a second photoreceptor group. The first photoreceptor group may change output voltages when overridden by the side edge of the sheet. The second photoreceptor group may include an opposite end of the plurality of photoreceptors being out of the side edge of the sheet. The controller, which may be part of the sheet detector mechanism, may be configured to adjust a light emission amount of the light source in accordance with characteristics of the sheet.
摘要翻译：片材检测器，片材检测器机构和图像形成装置。图像形成装置可以包括图像形成机构，片材输送机构和片材检测器。图像形成机构可以形成图像并将图像转印到由片材输送机构输送的片材上。片材检测器可以布置在图像转印区域的上游并且被配置为检测片材。片材检测器可以包括发射光的光源，多个光感受器和控制器。多个感光体可以沿主扫描方向排列成一行，并且可以包括第一感光体组和第二感光体组。当被片材的侧边缘覆盖时，第一感光体组可以改变输出电压。第二感光体组可以包括多个感光体的相对端在片材的侧边缘之外。可以是片材检测器机构的一部分的控制器可以被配置为根据片材的特性调节光源的发光量。

4. 发明授权

US08093361B2 Anti-perp antibody 有权
标题翻译：抗perp抗体
公开(公告)号：US08093361B2
公开(公告)日：2012-01-10
申请号：US11628745
申请日：2005-06-07
申请人： Atsushi Ochiai , Norihiko Shiraishi , Yoko Kato , Toshio Ota , Susume Sekine , Kenya Shitara , Akiko Furuya , So Ohta , Emi Hosaka , Yuka Sasaki
发明人： Atsushi Ochiai , Norihiko Shiraishi , Yoko Kato , Toshio Ota , Susume Sekine , Kenya Shitara , Akiko Furuya , So Ohta , Emi Hosaka , Yuka Sasaki
IPC分类号： C07K16/00 , C12P21/08 , A61K39/395 , A61K39/00 , C12P21/04 , G01N33/53 , G01N33/574
CPC分类号： G01N33/57492 , C07K16/28 , C07K2317/732 , C07K2317/734
摘要： The present invention provides an antibody which specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by PERP (p53 apoptosis effector related to PMP-22) gene and binds to the extracellular region. The antibody of the present invention is useful for treatment of various diseases which highly expresses a polypeptide encoded by the PERP gene. Also, a polypeptide encoded by the PERP gene or a cell expressing the polypeptide can be specifically detected by an immunological method using the antibody, so that the antibody is useful for diagnosis of various diseases related to PERP.
摘要翻译：本发明提供一种特异性识别由PERP编码的多肽的细胞外区域的三维结构的抗体（与PMP-22相关的p53凋亡效应）并结合到细胞外区域。本发明的抗体可用于治疗高表达由PERP基因编码的多肽的各种疾病。此外，可以通过使用抗体的免疫学方法来特异性检测由PERP基因编码的多肽或表达多肽的细胞，使得该抗体可用于诊断与PERP相关的各种疾病。

5. 发明申请

US20080118978A1 Anti-tumor agent 审中-公开
标题翻译：抗肿瘤剂
公开(公告)号：US20080118978A1
公开(公告)日：2008-05-22
申请号：US11730194
申请日：2007-03-29
申请人： Takashi Sato , Hiroyuki Ishida , Masao Asada , Takaaki Uochi , So Ohta
发明人： Takashi Sato , Hiroyuki Ishida , Masao Asada , Takaaki Uochi , So Ohta
IPC分类号： C12N5/06
CPC分类号： C07K16/40 , C07K16/2887 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/732 , C07K2317/734
摘要： The present invention provides an agent which is effective to a patient who is administered by an agent comprising anti-CD20 antibody as an active ingredient.
摘要翻译：本发明提供一种对于由包含抗CD20抗体作为活性成分的药剂施用的患者有效的药剂。

6. 发明授权

US08491902B2 Medicament comprising recombinant antibody against chemokine receptor CCR4 有权
标题翻译：包含针对趋化因子受体CCR4的重组抗体的药物
公开(公告)号：US08491902B2
公开(公告)日：2013-07-23
申请号：US10581413
申请日：2004-12-03
申请人： Kenya Shitara , Rinpei Niwa , So Ohta , Yuka Sasaki , Junji Kanazawa , Toshihiko Ishii , Shiro Akinaga
发明人： Kenya Shitara , Rinpei Niwa , So Ohta , Yuka Sasaki , Junji Kanazawa , Toshihiko Ishii , Shiro Akinaga
IPC分类号： A61K39/395
CPC分类号： A61K31/675 , A61K31/437 , A61K31/475 , A61K31/519 , A61K31/704 , A61K31/7048 , A61K38/193 , A61K38/2013 , A61K38/2086 , A61K38/212 , A61K39/395 , A61K39/39558 , A61K45/06 , C07K16/2866 , A61K2300/00
摘要： A medicament having a higher therapeutic effect than that provided by administration of a recombinant antibody against human CC chemokine receptor 4 or an antibody fragment thereof or an agent alone is provided.
摘要翻译：提供了具有比通过施用针对人CC趋化因子受体4或其抗体片段或单独的试剂的重组抗体提供的治疗效果更高的治疗效果的药物。

7. 发明授权

US07691367B2 Branched polyalkylene glycols 失效
标题翻译：支链聚亚烷基二醇
公开(公告)号：US07691367B2
公开(公告)日：2010-04-06
申请号：US10168956
申请日：2000-12-22
申请人： Motoo Yamasaki , Toshiyuki Suzuwa , Tatsuya Murakami , Noriko Sakurai , Kinya Yamashita , Mayumi Mukai , Takashi Kuwabara , So Ohta , Ichiro Miki
发明人： Motoo Yamasaki , Toshiyuki Suzuwa , Tatsuya Murakami , Noriko Sakurai , Kinya Yamashita , Mayumi Mukai , Takashi Kuwabara , So Ohta , Ichiro Miki
IPC分类号： A81K38/21
CPC分类号： C08G65/329 , A61K38/215 , A61K47/60 , A61K47/65 , A61K47/6889 , C08L2203/02
摘要： The present invention provides branched polyalkylene glycols useful as a chemically modifying agent for physiologically active polypeptides, wherein two single-chain polyalkylene glycols are linked to a group having a cyclic structure other than a plane structure, and wherein a group having reactivity with an amino acid side chain, an N-terminal amino group or a C-terminal carboxyl group in a polypeptide or a group convertible into the group having reactivity is linked to the group having a structure other than a plane structure.
摘要翻译：本发明提供可用作生理活性多肽的化学改性剂的支链聚亚烷基二醇，其中两个单链聚亚烷基二醇与除平面结构以外的环状结构的基团连接，并且其中与氨基酸具有反应性的基团侧链，多肽中的N-末端氨基或C-末端羧基或可转化成具有反应性的基团的基团与具有除了平面结构以外的结构的基团连接。

8. 发明申请

US20070020263A1 Medicine containing genetically modified antibody against chemokine receptor ccr4 有权
标题翻译：含有针对趋化因子受体ccr4的转基因抗体的药物
公开(公告)号：US20070020263A1
公开(公告)日：2007-01-25
申请号：US10581413
申请日：2004-12-03
申请人： Kenya Shitara , Rinpei Niwa , So Ohta , Yuka Sasaki , Junji Kanazawa , Toshihiko Ishii , Shiro Akinaga
发明人： Kenya Shitara , Rinpei Niwa , So Ohta , Yuka Sasaki , Junji Kanazawa , Toshihiko Ishii , Shiro Akinaga
IPC分类号： A61K39/395
CPC分类号： A61K31/675 , A61K31/437 , A61K31/475 , A61K31/519 , A61K31/704 , A61K31/7048 , A61K38/193 , A61K38/2013 , A61K38/2086 , A61K38/212 , A61K39/395 , A61K39/39558 , A61K45/06 , C07K16/2866 , A61K2300/00
摘要： A medicament having a higher therapeutic effect than that provided by administration of a recombinant antibody against human CC chemokine receptor 4 or an antibody fragment thereof or an agent alone is provided.
摘要翻译：提供了具有比通过施用针对人CC趋化因子受体4或其抗体片段或单独的试剂的重组抗体提供的治疗效果更高的治疗效果的药物。

9. 发明授权

US06996349B2 Image forming apparatus capable of determining type of recording sheet to prevent sheet jam 失效
公开(公告)号：US06996349B2
公开(公告)日：2006-02-07
申请号：US10757408
申请日：2004-01-15
申请人： So Ohta , Masataka Shimoohsako
发明人： So Ohta , Masataka Shimoohsako
IPC分类号： G03G15/00
CPC分类号： G03G15/5029 , G03G2215/00616 , G03G2215/00751
摘要： An image forming apparatus includes a recording sheet type detection device to automatically detect a type of a recording sheet. A setting device sets an image forming condition by an operator. The image forming condition includes the type of the recording sheet. An image forming device forms a visible image on the recording sheet. A sheet feeding device feeds the recording sheet to the image forming device. A controller controls the image forming apparatus not to form an image on the recording sheet when the image forming condition with regard to the type of the recording sheet set by the operator does not match the type of the recording sheet detected by the recording sheet type detection device.

10. 发明授权

US6103236A Toxin conjugates 失效
标题翻译：毒素结合物
公开(公告)号：US6103236A
公开(公告)日：2000-08-15
申请号：US981416
申请日：1997-11-10
申请人： Toshiyuki Suzawa , Motoo Yamasaki , Satoru Nagamura , Hiromitsu Saito , So Ohta , Nobuo Hanai
发明人： Toshiyuki Suzawa , Motoo Yamasaki , Satoru Nagamura , Hiromitsu Saito , So Ohta , Nobuo Hanai
IPC分类号： A61K39/44 , A61K47/48 , C07K17/06 , A61K39/395 , C07K16/00
CPC分类号： A61K47/48438 , A61K39/44 , A61K47/48407 , A61K47/48715 , C07K17/06
摘要： The present invention relates to a toxin conjugate in which a residue derived from a compound having an affinity for a target cell is bound to a toxin through a spacer comprising polyalkylene glycol and dipeptide.
摘要翻译： PCT No.PCT / JP96 / 01241 Sec。 371日期：1997年11月10日 102（e）1997年11月10日PCT PCT 1996年5月10日PCT公布。公开号WO96 / 35451 日本1996年11月14日本发明涉及一种毒素结合物，其中衍生自对靶细胞具有亲和力的化合物的残基通过包含聚亚烷基二醇和二肽的间隔物与毒素结合。

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