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    • 3. 发明授权
    • Detachable transfer conduit
    • 可拆卸输送导管
    • US08505586B2
    • 2013-08-13
    • US13054749
    • 2008-07-18
    • Michael A. Zumbrum
    • Michael A. Zumbrum
    • F16L55/16
    • A61M39/08A61M39/146B21D41/045B29C57/10B29C67/0014B29C2793/009Y10T156/1054
    • A disconnect transfer conduit comprising flexible tubing; a deformable sleeve surrounding a portion of the flexible tubing; wherein the sleeve is attached to the flexible tubing and is formed of a material having plasticity such that pressure applied to the sleeve causes the sleeve to deform about and seal the flexible tubing and upon continued application of pressure to the sleeve, the sleeve and flexible tubing are cut and the sleeve retains a deformed shape substantially sealing the tubing. Also provided is a method of sealing flexible tubing comprising applying pressure to a sleeve attached to flexible tubing to deform the sleeve and seal the tubing; wherein, applying further pressure to the sleeve to cut the sleeve and tubing, thereby leaving the tubing substantially sealed where cut.
    • 一种断开传输导管,包括柔性管; 围绕柔性管道的一部分的可变形套管; 其中所述套筒附接到所述柔性管道并且由具有可塑性的材料形成,使得施加到所述套筒的压力导致所述套筒围绕所述柔性管道变形并且密封所述柔性管道,并且在持续对所述套筒施加压力时,所述套筒和柔性管 被切割并且套筒保持基本上密封管道的变形形状。 还提供了一种密封柔性管的方法,包括向连接到柔性管的套筒施加压力以使套管变形并密封管; 其中,向套筒施加进一步的压力以切割套筒和管道,从而使管道在切割时基本上被密封。
    • 5. 发明申请
    • DETACHABLE TRANSFER CONDUIT
    • 可拆卸传输线
    • US20110155274A1
    • 2011-06-30
    • US13054749
    • 2008-07-18
    • Michael A. Zumbrum
    • Michael A. Zumbrum
    • F16L11/00B32B37/00
    • A61M39/08A61M39/146B21D41/045B29C57/10B29C67/0014B29C2793/009Y10T156/1054
    • A disconnect transfer conduit comprising flexible tubing; a deformable sleeve surrounding a portion of the flexible tubing; wherein the sleeve is attached to the flexible tubing and is formed of a material having plasticity such that pressure applied to the sleeve causes the sleeve to deform about and seal the flexible tubing and upon continued application of pressure to the sleeve, the sleeve and flexible tubing are cut and the sleeve retains a deformed shape substantially sealing the tubing. Also provided is a method of sealing flexible tubing comprising applying pressure to a sleeve attached to flexible tubing to deform the sleeve and seal the tubing; wherein, applying further pressure to the sleeve to cut the sleeve and tubing, thereby leaving the tubing substantially sealed where cut.
    • 一种断开传输导管,包括柔性管; 围绕柔性管道的一部分的可变形套管; 其中所述套筒附接到所述柔性管道并且由具有可塑性的材料形成,使得施加到所述套筒的压力导致所述套筒围绕所述柔性管道变形并且密封所述柔性管道,并且在持续对所述套筒施加压力时,所述套筒和柔性管 被切割并且套筒保持基本上密封管道的变形形状。 还提供了一种密封柔性管的方法,包括向连接到柔性管的套筒施加压力以使套管变形并密封管; 其中,向套筒施加进一步的压力以切割套筒和管道,从而使管道在切割时基本上被密封。
    • 6. 发明授权
    • Fluid transfer device
    • 流体输送装置
    • US08505396B2
    • 2013-08-13
    • US12688654
    • 2010-01-15
    • Michael A. Zumbrum
    • Michael A. Zumbrum
    • G01N1/00
    • A61M39/22A61M5/162A61M39/18A61M2039/226
    • A fluid transfer device for transferring fluid into or out of a fluid vessel, such as a tank, and is particularly useful in transferring fluids with particulates or high viscosity in a substantially aseptic, hygienic, or sterile manner. The device has a body with an elongate passage extending through the body. The body has a proximal end and a distal end. A longitudinally displaceable substantially hollow substantially hollow shaft is disposed in and extends along the passage in the body. A plug sealing the passage is at a first location. A diaphragm sealing the passage is at a second location intermediate the plug and the distal end of the passage. The shaft extends through and is secured to the diaphragm and has a fluid transfer opening between the diaphragm and the plug. Longitudinal displacement of the shaft causes the fluid transfer opening to be in fluid communication with a fluid vessel, the diaphragm stretching to accommodate the displacement of the shaft while maintaining an aseptic seal of the passage.
    • 流体输送装置,用于将流体输送进或流出流体容器,例如罐,并且特别适用于以基本上无菌,卫生或无菌的方式将微粒或高粘度的流体输送。 该装置具有延伸穿过本体的细长通道的主体。 身体具有近端和远端。 纵向位移的基本中空的基本上中空的轴被设置在主体中并沿其中的通道延伸。 密封通道的塞子处于第一位置。 密封通道的隔膜位于塞子和通道的远端之间的第二位置。 轴延伸穿过并固定到隔膜,并且在隔膜和插塞之间具有流体传送开口。 轴的纵向位移导致流体转移开口与流体容器流体连通,隔膜在保持通道的无菌密封的同时延伸以适应轴的位移。
    • 7. 发明申请
    • FLUID TRANSFER DEVICE
    • 流体传输装置
    • US20110155258A1
    • 2011-06-30
    • US13054743
    • 2008-07-18
    • Michael A. Zumbrum
    • Michael A. Zumbrum
    • F16K17/40
    • A61M39/18A61M2039/226B01L3/565B01L2300/0672B01L2400/0683B65B3/045G01N1/18Y10T137/1632
    • A device is provided for transferring fluid into or out of a tank and is particularly useful in transferring fluid in a substantially aseptic, hygienic, or sterile manner. The device has a body with an elongate passage extending through the body. The body has a proximal end and a distal end. A longitudinally displaceable cannula is disposed in and extends along the passage in the body. A septum sealing the passage is at a first location; the septum being pierceable and self-sealing. A diaphragm sealing the passage is at a second location intermediate the septum and the distal end of the passage. The cannula extends through and is secured to the diaphragm and has a sharpened end disposed adjacent to or in the septum. Longitudinal displacement of the cannula causes its sharpened end to pierce and project through the septum, the diaphragm stretching to accommodate the displacement of the cannula while maintaining its aseptic seal of the passage.
    • 提供了用于将流体输送到罐中或从罐中排出的装置,并且特别适用于以基本上无菌,卫生或无菌的方式输送流体。 该装置具有延伸穿过本体的细长通道的主体。 身体具有近端和远端。 纵向可移位的套管设置在身体内的通道中并沿其中延伸。 密封通道的隔膜位于第一位置; 隔膜是可刺破和自密封的。 密封通道的隔膜位于隔膜和通道的远端之间的第二位置。 套管延伸通过并固定到隔膜上,并且具有邻近隔膜或隔膜设置的尖端。 插管的纵向位移导致其尖锐的端部刺穿并突出通过隔膜,隔膜拉伸以适应插管的位移,同时保持其通道的无菌密封。
    • 9. 发明申请
    • FLUID TRANSFER DEVICE
    • 流体传输装置
    • US20100133459A1
    • 2010-06-03
    • US12688654
    • 2010-01-15
    • Michael A. Zumbrum
    • Michael A. Zumbrum
    • F16K1/00
    • A61M39/22A61M5/162A61M39/18A61M2039/226
    • A fluid transfer device for transferring fluid into or out of a fluid vessel, such as a tank, and is particularly useful in transferring fluids with particulates or high viscosity in a substantially aseptic, hygienic, or sterile manner. The device has a body with an elongate passage extending through the body. The body has a proximal end and a distal end. A longitudinally displaceable substantially hollow substantially hollow shaft is disposed in and extends along the passage in the body. A plug sealing the passage is at a first location. A diaphragm sealing the passage is at a second location intermediate the plug and the distal end of the passage. The shaft extends through and is secured to the diaphragm and has a fluid transfer opening between the diaphragm and the plug. Longitudinal displacement of the shaft causes the fluid transfer opening to be in fluid communication with a fluid vessel, the diaphragm stretching to accommodate the displacement of the shaft while maintaining an aseptic seal of the passage.
    • 流体输送装置,用于将流体输送进或流出流体容器,例如罐,并且特别适用于以基本上无菌,卫生或无菌的方式将微粒或高粘度的流体输送。 该装置具有延伸穿过本体的细长通道的主体。 身体具有近端和远端。 纵向位移的基本中空的基本上中空的轴被设置在主体中并沿其中的通道延伸。 密封通道的塞子处于第一位置。 密封通道的隔膜位于塞子和通道的远端之间的第二位置。 轴延伸穿过并固定到隔膜,并且在隔膜和插塞之间具有流体传送开口。 轴的纵向位移导致流体转移开口与流体容器流体连通,隔膜在保持通道的无菌密封的同时延伸以适应轴的位移。
    • 10. 发明授权
    • Fluid transfer device
    • 流体输送装置
    • US08613422B2
    • 2013-12-24
    • US13054743
    • 2008-07-18
    • Michael A. Zumbrum
    • Michael A. Zumbrum
    • F16L29/00G01N1/10
    • A61M39/18A61M2039/226B01L3/565B01L2300/0672B01L2400/0683B65B3/045G01N1/18Y10T137/1632
    • A device is provided for transferring fluid into or out of a tank and is particularly useful in transferring fluid in a substantially aseptic, hygienic, or sterile manner. The device has a body with an elongate passage extending through the body. The body has a proximal end and a distal end. A longitudinally displaceable cannula is disposed in and extends along the passage in the body. A septum sealing the passage is at a first location; the septum being pierceable and self-sealing. A diaphragm sealing the passage is at a second location intermediate the septum and the distal end of the passage. The cannula extends through and is secured to the diaphragm and has a sharpened end disposed adjacent to or in the septum. Longitudinal displacement of the cannula causes its sharpened end to pierce and project through the septum, the diaphragm stretching to accommodate the displacement of the cannula while maintaining its aseptic seal of the passage.
    • 提供了用于将流体输送到罐中或从罐中排出的装置,并且特别适用于以基本上无菌,卫生或无菌的方式输送流体。 该装置具有延伸穿过本体的细长通道的主体。 身体具有近端和远端。 纵向可移位的套管设置在身体内的通道中并沿其中延伸。 密封通道的隔膜位于第一位置; 隔膜是可刺破和自密封的。 密封通道的隔膜位于隔膜和通道的远端之间的第二位置。 套管延伸通过并固定到隔膜上,并且具有邻近隔膜或隔膜设置的尖端。 插管的纵向位移导致其尖锐的端部刺穿并突出通过隔膜,隔膜拉伸以适应插管的位移,同时保持其通道的无菌密封。