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1. 发明授权

US06667044B1 Cosmetic or dermatological gels based on microemulsions 失效
标题翻译：基于微乳液的化妆品或皮肤病学凝胶
公开(公告)号：US06667044B1
公开(公告)日：2003-12-23
申请号：US09269676
申请日：1999-06-18
申请人： Khiet Hien Diec , Wolfgang Meier , Jörg Schreiber
发明人： Khiet Hien Diec , Wolfgang Meier , Jörg Schreiber
IPC分类号： A61K700
CPC分类号： A61K8/894 , A61K8/042 , A61K8/064 , A61K8/068 , A61K8/39 , A61K8/4973 , A61K8/4993 , A61K8/86 , A61Q1/14 , A61Q5/00 , A61Q9/02 , A61Q15/00 , A61Q19/00 , A61Q19/002 , A61Q19/007 , A61Q19/10 , Y10S514/937 , Y10S514/938 , Y10S514/941 , Y10S514/943 , Y10S514/944
摘要： Microemulsion gels a) based on water in oil type microemulsions, comprising an oil phase which is essentially composed of not easily volatile components, an aqueous phase containing one or more polyethoxylated W/O emulsifiers and/or one or more polypropoxylated W/O emulsifiers and/or one or more polyethoxylated and polypropoxylated W/O emulsifiers and/or one or more monoesters, diesters, polyesters of polyols as W/O emulsifiers and/or one or more monoethers, diethers, polyethers of polyols as W/O emulsifiers and/or one or more dimethicone copolyols as W/O emulsifiers and/or one or more fatty alcohols or fatty acids as W/O emulsifiers and/or one or more sorbitan esters as W/O emulsifiers and/or one or more methyl glucose esters as W/O emulsifiers, and also comprising if desired one or more O/W emulsifiers, obtained in such a way that a mixture of basic components comprising an aqueous phase, an oil phase, one or more inventive emulsifiers is produced, being the HLB value of the emulsifier or emulsifier combination located between 2 and 14.
摘要翻译：微乳液凝胶a）基于油型微乳液，其包含基本上由不容易挥发的组分组成的油相，含有一种或多种聚乙氧基化W / O乳化剂的水相和/或一种或多种聚丙氧基化W / O乳化剂， /或一种或多种聚乙氧基化和聚丙氧基化W / O乳化剂和/或一种或多种单酯，二酯，多元醇的聚酯作为W / O乳化剂和/或一种或多种单醚，二醚，多元醇的聚醚作为W / O乳化剂和/ 或作为W / O乳化剂和/或作为W / O乳化剂和/或一种或多种脱水山梨醇酯的W / O乳化剂和/或一种或多种脂肪醇或脂肪酸的一种或多种聚二甲基硅氧烷共聚多元醇作为W / O乳化剂和/或一种或多种甲基葡萄糖酯， W / O乳化剂，并且还包括如果需要的一种或多种O / W乳化剂，其以如下方式获得：使得包含水相，油相，一种或多种本发明的乳化剂的碱性组分的混合物是HLB值的乳化剂呃或乳化剂组合位于2和14之间。

2. 发明授权

US06468551B1 Cosmetic or dermatological preparations based on emulsifiers which are free from ethylene oxide and propylene oxide, for the preparation of microemulsion gels 失效
标题翻译：基于不含环氧乙烷和环氧丙烷的乳化剂的化妆品或皮肤病学制剂，用于制备微乳液凝胶
公开(公告)号：US06468551B1
公开(公告)日：2002-10-22
申请号：US09269778
申请日：1999-06-18
申请人： Khiet Hien Diec , Wolfgang Meier , Jörg Schreiber
发明人： Khiet Hien Diec , Wolfgang Meier , Jörg Schreiber
IPC分类号： A61K700
CPC分类号： A61K8/042 , A61K8/062 , A61K8/068 , A61K9/1075 , A61Q19/00 , Y10S514/844 , Y10S514/846
摘要： Microemulsion gels a) based on oil in water type, comprising an oil phase, substantially consisting of not easily volatile constituents, and an aqueous phase containing one or more O/W emulsifiers free from ethylene oxide and propylene oxide and possibly one or more additional O/W emulsifiers, an emulsifier content which is lower than 20 wt. % related to the full weight of the microemulsion, obtained in such a way that a mixture of basic constituents, consisting of an aqueous phase, an oil phase, one or more O/W emulsifiers, possibly one or more additional O/W emulsifiers, possibly other auxiliary, additional or active agents, is made to react against each other in a mixing ratio so that a microemulsion can be obtained and b) in which droplets of discontinuous oil phase are bound to each other by one or more cross-linking substances, whose molecules are characterized by at least one hydrophylic area having a suitable expansion for bridging of distance between each microemulsion droplet and at least one hydropobic area, which can interact hydrophobically with the microemulsion droplets.
摘要翻译：微乳液凝胶a）基于水中的油，其包含基本上由不容易挥发的组分组成的油相，以及含有一种或多种不含环氧乙烷和环氧丙烷的O / W乳化剂的水相，以及可能的一种或多种另外的O / W乳化剂，乳化剂含量低于20wt。％的微乳液的重量相对于由水相，油相，一种或多种O / W乳化剂，可能一种或多种另外的O / W乳化剂组成的碱性组分的混合物，可能的其他助剂，附加或活性剂以混合比例彼此反应，从而可以获得微乳液，以及b）其中不连续油相的液滴通过一种或多种交联物质彼此结合其分子的特征在于具有至少一个亲水区域，其具有用于桥接每个微乳液液滴与可与微乳液液滴疏水相互作用的至少一个氢氧区域之间的距离的适当膨胀。

3. 发明授权

US06607733B1 Cosmetic or dermatological gels based on microemulsions 失效
标题翻译：基于微乳液的化妆品或皮肤病学凝胶
公开(公告)号：US06607733B1
公开(公告)日：2003-08-19
申请号：US08930404
申请日：1998-01-20
申请人： Khiet Hien Diec , Heinrich Gersbarlag , Manfred Klier , Jörg Schreiber , Florian Wolf
发明人： Khiet Hien Diec , Heinrich Gersbarlag , Manfred Klier , Jörg Schreiber , Florian Wolf
IPC分类号： A61K600
CPC分类号： A61K8/042 , A61K8/062 , A61K8/068 , A61K8/39 , A61K9/1075 , A61Q15/00 , Y10S514/941 , Y10S514/944
摘要： Microemulsion gels based on microemulsions of the oil-in-water type in which the droplets of the discontinuous oily phase are joined to one another by one or more crosslinking substances, the molecules of which are distinguished by at least one hydrophilic region, which has an extension which is capable of bridging the customary distance between the microemulsion droplets, and by at least one hydrophobic region, which is capable of entering into a hydrophobic interaction with the microemulsion droplets.
摘要翻译：基于油包水型的微乳液的微乳液凝胶，其中不连续油相的液滴通过一种或多种交联物质彼此连接，其分子由至少一个亲水区域区分，所述亲水区域具有其能够桥接微乳液液滴之间的常规距离，以及能够与微乳液液滴进行疏水相互作用的至少一个疏水区域。

4. 发明授权

US07811594B2 Crosslinked oil droplet-based cosmetic or pharmaceutical emulsions 有权
标题翻译：交联的油滴型化妆品或药物乳剂
公开(公告)号：US07811594B2
公开(公告)日：2010-10-12
申请号：US10953587
申请日：2004-09-28
申请人： Jörg Schreiber , Khiet Hien Diec
发明人： Jörg Schreiber , Khiet Hien Diec
IPC分类号： A61K8/02
CPC分类号： A61K8/062 , A61K8/06 , A61K8/39 , A61K8/86 , A61Q19/00
摘要： The invention is a crosslinked water-in-oil emulsion that is useful in cosmetic and pharmaceutical applications. The emulsion includes a water phase, oil phase, water-in-oil emulsifier, and one or more crosslinkers. The crosslinkers that are useful in the invention include molecules having at least one hydrophilic region and at least one hydrophobic region. The invention also includes a process for preparing the crosslinked emulsion.
摘要翻译：本发明是可用于化妆品和药物应用的交联油包水乳液。乳液包括水相，油相，油包水乳化剂和一种或多种交联剂。可用于本发明的交联剂包括具有至少一个亲水区和至少一个疏水区的分子。本发明还包括一种制备交联乳液的方法。

5. 发明授权

US06613338B1 Cosmetic and skin care sticks with high water contents 失效
标题翻译：化妆品和护肤品含有高含水量
公开(公告)号：US06613338B1
公开(公告)日：2003-09-02
申请号：US09284369
申请日：1999-04-14
申请人： Jörg Schreiber , Khiet Hien Diec , Florian Wolf , Manfred Klier
发明人： Jörg Schreiber , Khiet Hien Diec , Florian Wolf , Manfred Klier
IPC分类号： A61K600
CPC分类号： A61Q19/00 , A61K8/02 , A61K8/0229 , A61K8/39 , A61K8/86 , A61Q1/06 , A61Q1/10 , A61Q17/04 , Y10S514/938 , Y10S514/941
摘要： Lipsticks, antiacne sticks, sunscreen sticks and eyeshadow sticks, with a high water content, characterized in that they comprise (a) a lipid phase, which comprises (a1) at least one oil component (a2) at least one wax component (a3) optionally other substances soluble or dispersible in the lipid phase, (b) an aqueous phase, which comprises (b1) from 30 to 85% by weight of water, based on the total weight of the stick composition and (b2) if desired, substances soluble or dispersible in water, (c) at least one active ingredient or several chosen from the active ingredients known for lipsticks, antiacne sticks, sunscreen sticks and eyeshadow sticks, (d) a W/O emulsifier or a mixture of two or more W/O emulsifiers, (e) one or more stabilizers, chosen from the group of substances of the general structure A—B—A′, where A and A′ are identical or different hydrophobic organic radicals, and B is a hydrophilic group, (f) if desired, further surface-active substances as coemulsifiers, and also, if desired, stabilizers and further customary cosmetic and/or pharmaceutical auxiliaries, active ingredients and/or additives.
摘要翻译：具有高水分含量的唇膏，抗痤疮棒，防晒霜和眼影棒，其特征在于它们包含（a）脂质相，其包含（a1）至少一种油组分（a2）至少一种蜡组分（a3）任选的其它可溶于或可分散在脂质相中的物质，（b）水相，其包含（b1）30至85重量％的水，基于棒组合物的总重量，和（b2）如果需要，物质（c）至少一种活性成分或几种，其选自已知用于唇膏，抗痤疮棒，防晒霜和眼影棒的活性成分，（d）W / O乳化剂或两种或更多种W的混合物 / O乳化剂，（e）一种或多种选自一般结构AB-A'的物质的稳定剂，其中A和A'是相同或不同的疏水性有机基团，B是亲水基团，（f）如果需要，可以使用作为辅助乳化剂的更多的表面活性物质，以及如果需要的话，稳定剂和进一步的常规化妆品和/或药物助剂，活性成分和/或添加剂。

6. 发明授权

US06773703B1 Protein-containing hydrogels 失效
标题翻译：含蛋白质的水凝胶
公开(公告)号：US06773703B1
公开(公告)日：2004-08-10
申请号：US09493887
申请日：2000-01-28
申请人： Norbert Ettner , Michael Schink , Jörg Schreiber , Wolfgang Meier , Marc Sauer
发明人： Norbert Ettner , Michael Schink , Jörg Schreiber , Wolfgang Meier , Marc Sauer
IPC分类号： A61K3843
CPC分类号： A61K38/44 , A61K38/446 , A61K38/465 , A61K38/47 , A61K38/4826 , A61K38/4886 , A61K2300/00
摘要： Hydrogel comprising at least one protein and/or enzyme and/or SOD/catalase enzyme mimic and PEGs, and parts of proteins and enzymes and/or recombinant proteins and enzymes, the proteins and/or enzymes being connected to the PEGs via urea groups.
摘要翻译：包含至少一种蛋白质和/或酶和/或SOD /过氧化氢酶模拟物和PEG，以及部分蛋白质和酶和/或重组蛋白质和酶的水凝胶，所述蛋白质和/或酶通过尿素基团连接到PEG。

7. 发明授权

US08435546B2 Cosmetic, dermatological or pharmaceutical preparations of lipid/wax mixtures containing gases 有权
标题翻译：包含气体的脂/蜡混合物的化妆品，皮肤病学或药物制剂
公开(公告)号：US08435546B2
公开(公告)日：2013-05-07
申请号：US11335472
申请日：2006-01-20
申请人： Jörg Schreiber , Frank Teuber , Martin Sattler
发明人： Jörg Schreiber , Frank Teuber , Martin Sattler
IPC分类号： A61K8/00
CPC分类号： A61Q19/00 , A61K8/0216 , A61K8/046 , A61K8/19 , A61K8/345 , A61K8/92 , A61K2800/33
摘要： A cosmetic, dermatological or pharmaceutical preparation comprising from 10% to 99% by weight of one or more lipids, from 1% to 90% by weight of one or more waxes and at least 20% by volume of one or more gases.
摘要翻译：一种化妆品，皮肤病学或药物制剂，其包含10重量％至99重量％的一种或多种脂质，1至90重量％的一种或多种蜡和至少20体积％的一种或多种气体。

8. 发明授权

US08329200B2 Cosmetic or dermatological stick 有权
标题翻译：化妆品或皮肤病棒
公开(公告)号：US08329200B2
公开(公告)日：2012-12-11
申请号：US10812469
申请日：2004-03-29
申请人： Anja Bauer , Albrecht Dörschner , Alexander Filbry , Anja Göppel , Ghita Lanzendörfer , Kirsten Schneider , Jens Schulz , Jörg Schreiber , Jessica Stelling , Mirko Tesch
发明人： Anja Bauer , Albrecht Dörschner , Alexander Filbry , Anja Göppel , Ghita Lanzendörfer , Kirsten Schneider , Jens Schulz , Jörg Schreiber , Jessica Stelling , Mirko Tesch
IPC分类号： A61K8/02 , A61K8/00 , A61K8/18 , A61Q17/04 , A61Q1/04 , A61Q1/06
CPC分类号： A61Q19/08 , A61K8/0229 , A61K8/064 , A61K8/345 , A61K8/37 , A61K8/375 , A61K8/86 , A61K8/922 , A61K8/925 , A61K31/00 , A61Q1/02 , A61Q1/06 , A61Q1/10 , A61Q17/04 , A61Q19/00 , A61Q19/001 , A61Q19/004 , A61Q19/02
摘要： The present invention is a water-in-oil emulsion having a high content of water and relatively high amounts of skin-moisturizing agents and a cosmetic or dermatological stick including the water-in-oil emulsion. The present invention also includes methods of moisturizing the skin using the water-in-oil emulsion. The water-in-oil emulsion is solid at room temperature and comprises a fatty phase with at least one oil component and at least one wax component, an aqueous phase with a skin-moisturizing agent in addition to water, a water-in-oil emulsifier having the general structure A-B-A′, where A′ and A′ represent the same or different hydrophobic inorganic groups and B is a hydrophilic group.
摘要翻译：本发明是具有高含量水分和相对高量的皮肤保湿剂的油包水乳液和包含油包水乳液的化妆品或皮肤病学棒。本发明还包括使用油包水乳液来保湿皮肤的方法。油包水乳液在室温下是固体，并且包含具有至少一种油组分和至少一种蜡组分的脂肪相，除了水之外还含有皮肤保湿剂的水相，油包水具有一般结构ABA'的乳化剂，其中A'和A'表示相同或不同的疏水性无机基团，B是亲水基团。

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