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    • 1. 发明授权
    • X-ray, neutron or electron diffraction method using an imaging plate and
apparatus therefor
    • 使用成像板的X射线,中子或电子衍射方法及其装置
    • US5936255A
    • 1999-08-10
    • US890623
    • 1997-07-09
    • Kenji NakanishiAkira TsukamotoKeiichi Tanabe
    • Kenji NakanishiAkira TsukamotoKeiichi Tanabe
    • G01N23/20G01N23/205G01N23/223G21K1/06G21K4/00G01N23/207
    • G21K1/06G21K2201/068
    • An X-ray, neutron or electron diffraction method, which is devoid of the defects of conventional diffraction apparatus using an imaging plate, which can analyzing a sample, in a non-destructive mode without contact and with a good S/N ratio, even when the sample significantly generates fluorescence or scattered X-rays. The method includes the steps of irradiating a predetermined area of the sample with an X-ray, neutron or electron beam whose axis is oriented at a fixed direction to obtain a diffraction ray, rotating the sample while maintaining the irradiated predetermined area substantially unchanged and while maintaining the angle between the axis of the X-ray, neutron or electron beam relative to the tangential plane of the predetermined area substantially unchanged, forming an image of the diffraction ray from the sample during the rotation of the sample through every predetermined angle using an imaging plate, reading a data of the image formed on the imaging plate to obtain an output data for each rotation of the sample through the predetermined angle, and processing the output data to obtain desired analysis information.
    • 一种X射线,中子或电子衍射方法,其不含常规的使用成像板的衍射装置的缺陷,该成像板能够以非破坏性的方式分析样品,无接触和良好的S / N比,甚至 当样品显着产生荧光或散射的X射线。 该方法包括以下步骤:用X轴,中子或电子束照射样品的预定区域,该X射线,中子或电子束的轴线沿固定方向取向以获得衍射光线,使样品旋转,同时保持照射的预定面积基本上不变,同时 保持X射线,中子或电子束相对于预定面积的切向面之间的角度基本上不变,在样品旋转期间通过每个预定角度形成来自样品的衍射光线的图像,使用 读取形成在成像板上的图像的数据,以获得用于样品的每次旋转的预定角度的输出数据,并处理输出数据以获得期望的分析信息。
    • 5. 发明授权
    • Magnetic immunoassay system
    • 磁免疫测定系统
    • US08945469B2
    • 2015-02-03
    • US11715916
    • 2007-03-09
    • Akira TsukamotoKazuo Saitoh
    • Akira TsukamotoKazuo Saitoh
    • G01N33/543
    • G01N33/54326
    • A magnetic immunoassay system with a mechanism for compensating the direct current residual magnetic field in the vicinity of the specimen measurement position, in a direction perpendicular to the magnetic marker direction of magnetization for the measurement target. This invention reduces the effects of the magnetic field emitted from the unbound magnetic marker due to the residual magnetic field in the specimen solution and detects with high sensitivity the signal of the bound target magnetic marker. The magnetic field at the measurement position is regulated so as to intersect the direction of magnetization of the magnetic marker for the measurement target, in order to make the magnetization direction of the magnetic marker that is unbound due to residual magnetism or remanence in the sample solution, intersect the magnetization direction of the magnetic marker for the measurement target. The signal of the bound target magnetic marker can be therefore measured with high sensitivity since it is isolated from the unbound magnetic marker signal.
    • 一种磁性免疫测定系统,其具有用于在垂直于测量对象的磁标记磁化方向的方向上补偿样本测量位置附近的直流残余磁场的机构。 本发明减少了由于样品溶液中的残留磁场而导致的未结合磁性标记物发射的磁场的影响,并以高灵敏度检测结合的目标磁性标记的信号。 调整测量位置处的磁场,以便与测量对象的磁性标记的磁化方向相交,以使磁性标记的磁化方向由于样品溶液中的剩余磁性或剩磁而未结合 与测量对象的磁性标记的磁化方向相交。 因此,可以高灵敏度地测量结合目标磁标记的信号,因为它与未结合的磁标记信号隔离。
    • 6. 发明授权
    • Immunoassay system and immunoassay method
    • 免疫测定系统和免疫测定法
    • US07993581B2
    • 2011-08-09
    • US11006757
    • 2004-12-08
    • Yusuke SekiAkira TsukamotoDaisuke SuzukiMasahiro YamaokaNami SugitaAkihiko KandoriKazuo Saitoh
    • Yusuke SekiAkira TsukamotoDaisuke SuzukiMasahiro YamaokaNami SugitaAkihiko KandoriKazuo Saitoh
    • G01N1/36G01N33/553
    • G01N33/54373G01N27/745
    • The present invention provides an immunoassay technique which enables efficient detection of antigen-antibody reaction with high sensitivity by a magnetic method using magnetic particles and a SQUID magnetic sensor or sensors. A system based on the technique includes a disk-shaped sample holder which holds on a circle a plurality of sample containers for accommodating marked samples, resulting from marking of samples with magnetic particles by antigen-antibody reaction; rotating means for rotating the holder around its central shaft; magnetizing means for magnetizing the marked samples outside a magnetic shield; and a magnetic sensor for detecting, within the magnetic shield, magnetic fields generated from the marked samples which have been magnetized. By rotation of the holder, areas fixing and holding different ones of the sample containers are successively inserted into the magnetic shield, and the magnetization of the marked samples accommodated in first ones of the sample containers and the detection of magnetic fields generated from the marked samples accommodated in second ones of the sample containers are executed in parallel.
    • 本发明提供了一种免疫测定技术,其能够通过使用磁性颗粒和SQUID磁性传感器的磁性方法高灵敏度地高效检测抗原 - 抗体反应。 基于该技术的系统包括:盘形样品保持器,其保持圆圈上的多个样品容器,用于容纳标记的样品,通过抗原 - 抗体反应用磁性颗粒标记样品; 用于使支架围绕其中心轴旋转的旋转装置; 用于将标记样品磁化在磁屏蔽外的磁化装置; 以及磁传感器,用于在磁屏蔽内检测从已经被磁化的标记样品产生的磁场。 通过保持器的旋转,将固定和保持不同样本容器的区域依次插入到磁屏蔽中,并且标记的样品的磁化容纳在第一个样品容器中,并且检测从标记的样品产生的磁场 容纳在第二个样品容器中并行执行。
    • 7. 发明授权
    • Manufacturing method of solid-state imaging device
    • 固态成像装置的制造方法
    • US07585694B2
    • 2009-09-08
    • US11884017
    • 2006-03-22
    • Akira Tsukamoto
    • Akira Tsukamoto
    • H01L21/00
    • H01L29/66946H01L27/14806H01L27/14831
    • Provided is a manufacturing method of a CCD solid-state imaging device having such an impurity concentration distribution with which shading is reduced and formation of a buried channel endowed with a large saturation signal charge amount is made possible. The manufacturing method includes: an oxide layer forming step of forming an oxide layer (12) on a semiconductor substrate (11); an ion implantation step of performing ion implantation through the oxide layer (12) to the semiconductor substrate (11) thereby forming a well in a position corresponding to a charge transfer portion; and an insulation layer forming step of performing insulation layer forming processing to the oxide layer (12) having undergone the ion implantation step, at least in a position corresponding to the well.
    • 提供了具有这样的杂质浓度分布的CCD固态成像装置的制造方法,阴影减少,并且形成具有大的饱和信号电荷量的掩埋通道成为可能。 制造方法包括:在半导体基板(11)上形成氧化物层(12)的氧化物层形成工序; 离子注入步骤,通过氧化物层(12)进行到半导体衬底(11)的离子注入,从而在对应于电荷转移部分的位置形成阱; 以及绝缘层形成步骤,至少在对应于所述阱的位置中,对经过离子注入步骤的氧化物层(12)进行绝缘层形成处理。
    • 8. 发明申请
    • Manufacturing Method of Solid-State Imaging Device
    • 固态成像装置的制造方法
    • US20080213935A1
    • 2008-09-04
    • US11884017
    • 2006-03-22
    • Akira Tsukamoto
    • Akira Tsukamoto
    • H01L21/8234
    • H01L29/66946H01L27/14806H01L27/14831
    • Provided is a manufacturing method of a CCD solid-state imaging device having such an impurity concentration distribution with which shading is reduced and formation of a buried channel endowed with a large saturation signal charge amount is made possible. The manufacturing method includes: an oxide layer forming step of forming an oxide layer (12) on a semiconductor substrate (11); an ion implantation step of performing ion implantation through the oxide layer (12) to the semiconductor substrate (11) thereby forming a well in a position corresponding to a charge transfer portion; and an insulation layer forming step of performing insulation layer forming processing to the oxide layer (12) having undergone the ion implantation step, at least in a position corresponding to the well.
    • 提供了具有这样的杂质浓度分布的CCD固态成像装置的制造方法,阴影减少,并且形成具有大的饱和信号电荷量的埋入通道成为可能。 制造方法包括:在半导体基板(11)上形成氧化物层(12)的氧化物层形成工序; 离子注入步骤,通过氧化物层(12)进行到半导体衬底(11)的离子注入,从而在对应于电荷转移部分的位置形成阱; 以及绝缘层形成步骤,至少在对应于所述阱的位置中,对经过离子注入步骤的氧化物层(12)进行绝缘层形成处理。
    • 9. 发明申请
    • Advertisement search agent
    • 广告搜索代理
    • US20070206596A1
    • 2007-09-06
    • US11705105
    • 2007-02-12
    • Yuichi IshikawaAkira Tsukamoto
    • Yuichi IshikawaAkira Tsukamoto
    • H04L12/56
    • H04L67/22H04L12/1863
    • An advertisement search agent detects a service that is provided by a node or a service that can be used by a node immediately after the node is newly connected to a domain. A message acquisition unit acquires an advertisement search message broadcast or multicast by a node connected to either one of a plurality of domains. A message database stores advertisement search messages acquired by the message acquisition unit. A node connection monitoring unit detects the connection of a node to either one of a plurality of domains. When the connection of a node is detected by the node connection monitoring unit, a delivery message extractor extracts an advertisement search message stored in the message database. A message delivery unit delivers the advertisement search message extracted by the delivery message extractor.
    • 广告搜索代理检测在节点被新连接到域之后立即被节点使用的节点或服务提供的服务。 消息获取单元通过连接到多个域中的任一个的节点获取广播或多播的广告搜索消息。 消息数据库存储由消息获取单元获取的广告搜索消息。 节点连接监视单元检测节点与多个域中的任一个的连接。 当节点连接监视单元检测到节点的连接时,传送消息提取器提取存储在消息数据库中的广告搜索消息。 消息传送单元传送由传递消息提取器提取的广告搜索消息。
    • 10. 发明申请
    • Immunoassay system and immunoassay method
    • 免疫测定系统和免疫测定法
    • US20050202572A1
    • 2005-09-15
    • US11006757
    • 2004-12-08
    • Yasuke SekiAkira TsukamotoDaisuke SuzukiMasahiro YamaokaNami SugitaAkihiko KandoriKazuo Saitoh
    • Yasuke SekiAkira TsukamotoDaisuke SuzukiMasahiro YamaokaNami SugitaAkihiko KandoriKazuo Saitoh
    • G01N33/53G01N27/72G01N33/542G01N33/553
    • G01N33/54373G01N27/745
    • The present invention provides an immunoassay technique which enables efficient detection of antigen-antibody reaction with high sensitivity by a magnetic method using magnetic particles and a SQUID magnetic sensor or sensors. A system based on the technique includes a disk-shaped sample holder which holds on a circle a plurality of sample containers for accommodating marked samples, resulting from marking of samples with magnetic particles by antigen-antibody reaction; rotating means for rotating the holder around its central shaft; magnetizing means for magnetizing the marked samples outside a magnetic shield; and a magnetic sensor for detecting, within the magnetic shield, magnetic fields generated from the marked samples which have been magnetized. By rotation of the holder, areas fixing and holding different ones of the sample containers are successively inserted into the magnetic shield, and the magnetization of the marked samples accommodated in first ones of the sample containers and the detection of magnetic fields generated from the marked samples accommodated in second ones of the sample containers are executed in parallel.
    • 本发明提供了一种免疫测定技术,其能够通过使用磁性颗粒和SQUID磁性传感器的磁性方法高灵敏度地高效检测抗原 - 抗体反应。 基于该技术的系统包括:盘形样品保持器,其保持圆圈上的多个样品容器,用于容纳标记的样品,通过抗原 - 抗体反应用磁性颗粒标记样品; 用于使支架围绕其中心轴旋转的旋转装置; 用于将标记样品磁化在磁屏蔽外的磁化装置; 以及磁传感器,用于在磁屏蔽内检测从已经被磁化的标记样品产生的磁场。 通过保持器的旋转,将固定和保持不同样本容器的区域依次插入到磁屏蔽中,并且标记的样品的磁化容纳在第一个样品容器中,并且检测从标记的样品产生的磁场 容纳在第二个样品容器中并行执行。