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1. 发明申请

US20060079500A1 Medicament and method for reducing alcohol and/or tobacco consumption 审中-公开
标题翻译：用于减少酒精和/或烟草消费的药物和方法
公开(公告)号：US20060079500A1
公开(公告)日：2006-04-13
申请号：US10523012
申请日：2003-07-25
申请人： Joachim Moormann , Klaus Opitz , Hermann Mucke
发明人： Joachim Moormann , Klaus Opitz , Hermann Mucke
IPC分类号： A61K31/55 , A61K31/4439
CPC分类号： A61K31/5513 , A61K31/465 , A61K31/55
摘要： The present invention relates to a medicament for treating addiction craving which is characterized in that the medicament consists of a combination of two administration forms, one of the administration forms continuously releasing at least one modulator of nicotinic receptors and the other administration form enabling a rapid entry of galanthamine into the central nervous system, as well as a two-stage method for the therapy of substance craving through modulation of neuronal nicotinic receptors, wherein a permanent treatment with a pharmaceutical administration form which continuously delivers a modulator of nicotinic receptors is supplemented upon the appearance of a strong craving for a substance by administering galanthamine or a pharmacologically acceptable salt thereof by means of an administration form which enables rapid entry of this modulator into the central nervous system.
摘要翻译：本发明涉及一种用于治疗成瘾渴求的药物，其特征在于药物由两种给药形式的组合组成，其中一种施用形式连续释放至少一种烟碱样受体调节剂，另一种施用形式能够快速进入加兰他敏加入中枢神经系统，以及通过调节神经元烟碱受体来治疗物质渴求的两阶段方法，其中使用药物施用形式的永久性治疗，其连续递送烟碱样受体的调节剂在通过施用加兰他敏或其药理学上可接受的盐通过能够将该调节剂快速进入中枢神经系统的给药形式来强烈渴望物质的出现。

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